논 비점오염 저감을 위한 최적관리기법(BMP) 보급 효과 분석

나영광 ( Young Kwang Na ),이수인 ( Su In Lee ),장정렬 ( Jung Ryeol Jang ),주소희 ( So Hee Ju ),최중대 ( Joong Dae Choi ) 한국농공학회 2016 한국농공학회 학술대회초록집 Vol.2016 No.-

본 연구에서는 최적관리기법(BMP)을 실제 영농지역에 보급하여, 광역단위 논에서 발생하는 비점오염물질의 저감효과를 분석하고자 하였다. 현재까지 선행 연구들을 통해 다양한 BMP 효과 검증이 이루어졌으나, 실제 영농지역 농민들에게 BMP를 보급하여 그 효과를 측정한 연구는 부족한 실정이다. 이에 본 연구에서는 광역단위 논 지역을 대상으로 물관리기술(물꼬)과 시비관리기술(완효성 비료)을 보급하고 강우시와 비강우 모니터링을 통해 BMP 효과를 측정하였다. 연구 대상지구는 전라북도 부안군 백산면 용계리 일대로 새만금 지역에 위치하여 있다. BMP 보급 효과를 분석하기 위하여 먼저 참여농민과 농지를 선정하였으며, 관개지역과 배수면적을 구분하여 모니터링 조사 지점을 선정하였다. 연구대상지구는 SO#1(완효성 비료 95%, 비참여 농가 5%), SO#2(완효성 비료2%, 물꼬 8%, 완효성비료 + 물꼬 40%), SO#M(완효성 비료 96%, 비 참여 농가 4%) 총 3개의 배출구로 구분하였다. 각 지구별 오염부하량을 측정한 결과, 대조구 대비 SO#1에서는 수질항목별로 10.6 ∼ 85.5%, SO#2는 8.1 ∼ 45.9%, SO#M은 10.7 ∼ 86.2%의 범위로 저감된 것으로 분석되었다. 특히, SS의 단위면적당 오염부하 저감율이 가장 큰 것으로 나타났으며, TOC의 단위 면적당 오염부하 저감율은 가장 작은 것으로 나타났다. 하지만 본 연구 결과는 7월부터 10월까지 측정한 데이터를 활용하여 산정한 결과로 써레질, 이앙기간에 발생한 단위면적당 오염부하량은 포함되지 않은 결과이다, 따라서 추가적인 연구를 통해 효과를 검증할 필요가 있을 것으로 판단된다.

방향족 수질오염원의 무한희석 활동도 계수의 측정 및 예측

최중소 광운대학교 신기술연구소 1999 신기술연구소논문집 Vol.28 No.-

수질을 오염시키는 방향족 화합물의 열역학적 거동을 설명하기 위하여 gas chromatograph(GC)을 이용하여 solute(1)/water(2)계에 대하여 333.15K~413.15K의 온도범위에서 무한희석 방향족 화합물의 활동도 계수가 측정되었다. 활동도 계수는 온도가 상승함에 따라 감소하는 결과로 나타나 오염성분의 처리가 저온보다는 고온영역에서 잘 이루어질 수 있다는 기준을 제시하였다. 무한희석시 물 속에서 용질의 활동도 계수를 예측하기 위하여 group contribution 모델인 UNIFAC이 적용되었고, 예측 결과는 실험치에 비교하여 10% 미만의 예측 오차범위에서 만족할 만한 결과를 얻었다. Infinite dilution activity coefficients were measured with a gas chromatograph to investigate the thermodynamic behavior of each aromatic compound which polluted the water for solute(1)/water(2) systems within 333.15K to 413.15K. They were decreased according to an increment of temperature and their results proved that the treatment of a pollution component of water get accomplished well in the high temperature region than in the low temperature range. The UNIFAC was applied to predict the infinite dilution activity coefficients of each solute in water. The predicted values were agreed with the experimental data within the 10% error ranges.

키랄 HPLC를 이용한 라세미 케토프로펜의 광학분할

김소영,이중기,서성섭,최민호,박태진,박달근 한국화학공학회 2001 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.39 No.6

케토프로펜은 비스테로이드 계통의 진통 및 소염제로서 류마티즘, 관절염 등을 위한 진통제나 해열제로 널리 사용되고 있다. 그러나 케토프로펜이 치료약으로 사용될 때 S-(+)-Ketoprofen이 주로 약리적 활성을 나타내고 R-(-)-Ketoprofen은 불활성이거나 오히려 부작용을 일으키는 문제점을 나타내고 있다. 본 연구에서는 케토프로펜 대장체(enantiomer)를 다양한 키랄 HPLC 칼럼을 이용하여 광학분할을 수행하면서 적합한 분리조건을 조사하였다. 고정상을 찾는 실험에서는 β-CD(β-cyclodextrin) BR®과 Kromasil® 칼럼을 이용하여 실험을 하였고, 이동상의 최적의 조성비를 찾는 실험도 수행하였다. 이 과정에서 라세미 Ketoprofen의 분리도는 사용된 키랄 고정상과 이동상의 조성비에 크게 영향을 받는다는 것을 알 수 있었다. 따라서 고정상으로는 Kromasil® 칼럼을 선택하고 이동상의 유속, 주입부피 그리고 주입농도가 라세미 Ketoprofen의 분리에 미치는 영향을 조사하였다. 실험결과 주입부피가 증가함에 따라서 분리도는 감소하였으나 이동상 유속이 증가함에 따라서 주입부피의 증가가 분리도에 미치는 영향은 점차 감소하는 것을 알 수 있었다. Ketoprofen, a phenylpropionic acid derivative, is a non-steroidal anti-inflammatory drug(NSAID) that has analgesic, anti-inflammatory and antipyretic properties. Pharmacological activity has been attributed mainly to the S-(+)-enantiomer, while the R-(-)-enantiomer is either inactive or has side effect. The optical separation of Ketoprofen enantiomers was carried out by various chiral HPLC(chiral high-performance liquid chromatography) columns and most compatible separation conditions of Ketoprofen enantiomers were investigated. The resolution and enantio selectivity of Ketoprofen were found to be strongly influenced by the employed chiral stationary phases(CSPs) and composition of eluents. The employed chiral stationary phases(CSPs) in this study were β-CD BR® and Kromasil®. The optimum composition of eluent was obtained differently for stationary material phase. The effects of process variables such as flow rate, injection volume, and concentration of eluent on Ketoprofen enantiomers separation were investigated using Kromasil® columns. The resolution decreased with the increase of injection volume, however, the effect became insignificant at higher flow rate.

Malignant Adenomyoepithelioma of the Breast Presenting as a Large Mass that Grew Slowly without Metastasis

So-young Choi,Joong Suck Kim,Sei Joong Kim,Yun Jeong Kim,Lucia Kim,Young Up Cho 한국유방암학회 2009 Journal of breast cancer Vol.12 No.3

An adenomyoepithelioma (AME) is an uncommon neoplasm characterized by proliferation of both epithelial and myoepithelial cells in the salivary gland, skin, lung and breast. AMEs can recur, progress to malignancy and metastasize. A 68-year-old woman presented a large mass occupying her whole right breast. The mass had grown slowly for about 20 years and the preoperative biopsy of the mass was chondroid syringoma. The mass was completely resected and the postoperative biopsy revealed malignant AME with a negative resection margin. The patient didn’t receive any adjuvant therapy and has been free of recurrence or metastasis up to now. We report herein a case of a malignant AME that was diagnosed in the largest breast mass reported to date. This mass grew slowly and without metastasis. Clinicians should consider this rare disease entity in the differential diagnosis of a breast mass and remember the importance of complete excision of this tumor.

Mini Review : Shedding; towards a new paradigm of syndecan function in cancer

( So Joong Choi ),( Ha Won Lee ),( Jung Ran Choi ),( Eok Soo Oh ) 생화학분자생물학회 (구 한국생화학분자생물학회) 2010 BMB Reports Vol.43 No.5

Syndecans, cell surface heparansulfate proteoglycans, have been proposed to act as cell surface receptors and/or coreceptors to play critical roles in multiple cellular functions. However, recent reports suggest that the function of syndecans can be further extended through shedding, a cleavage of extracellular domain. Shedding constitutes an additional level for controlling the function of syndecans, providing a means to attenuate and/or regulate amplitude and duration of syndecan signals by modulating the activity of syndecans as cell surface receptors. Whether these remaining cleavage products are still capable of functioning as cell surface receptors to efficiently transduce signals inside of cells is not clear. However, shedding transforms cell surface receptor syndecans into soluble forms, which, like growth factors, may act as novel ligands to induce cellular responses by association with other cell surface receptors. It is becoming interestingly evident that shed syndecans also contribute significantly to syndecan functions in cancer biology. This review presents current knowledge about syndecan shedding and its functional significance, particularly in the context of cancer. [BMB reports 2010; 43(5): 305-310]

Novel Antimicrobial Peptides Identified from Screening of Random Peptide Library by Yeast Two Hybrid Assay

Joong-Kook Choi, In-sook Jeon, So-Hee Jeong, Kang-Duk Choi, Sung Hoon Kim, Hak-Kyo Lee, Seung-Ryul Kim 충북대학교 동물의학연구소 2011 Journal of Biomedical and Translational Research Vol.12 No.4

Antimicrobial peptides are widely found in living organisms and are known to play a critical role in innate immunity. Numerous antimicrobial peptides from diverse species appear to be effective against pathogenic microorganisms of bacteria, fungi, protozoa, and viruses. Because antibiotic resistance is a global health issue in the fight against pathogenic microorganisms, there has been an urgent need for development of new antibiotic substances. In the current study, we performed yeast two hybrid screening using Beclin1 bait in order to find new peptide antibiotics from a random peptide library. Two candidate peptides from the screening were expressed in a yeast secretory system of Pichia pastoris and tested for any antimicrobial activity against Staphylococcus aureus, MRSA, MRSA2242, MRSA2250, Lactobacillus casei, and Lactobacillus acidophilus. Disc clear zone assay and spectrophotometric analysis revealed that the two peptides exert a decent activity against the pathogenic bacteria, in contrast to minimal effect on the commensal Lactobacillus strains. Taken together, this study presents novel peptides with antibacterial activity against the pathogenic forms of Staphylococcus aureus and suggests the possibility that these peptides, upon further characterization, may be developed as clinically useful antibiotics.

Vapor-Liquid Equilibrium Calculation of Four Binary Systems Containing Environmentally Acceptable Refrigerants

Joong So Choi,Myoung Hun Lee,Sang Soon Park,Jung Ho Cho 한국공업화학회 2003 Journal of Industrial and Engineering Chemistry Vol.9 No.2

Poster Session : Cancer Biology ; MMP-7 regulates syndecan-2 shedding in colon cancer cell

( So Joong Choi ),( Eok Soo Oh ) 한국생화학분자생물학회 (구 한국생화학회) 2007 생화학분자생물학회 춘계학술발표논문집 Vol.2007 No.-

Application of NRTL and UNIQUAC Models to Liquid - Liquid Systems with Halogen Salts (Part Ⅰ)

Choi, Joong So,Park, Dong Won,Rhim, Jin Nam 한국화학공학회 1988 NICE Vol.6 No.1

Binodal curves, tie lines, and plait points for benzenehalogen salt solutions-n-propanol systems were determined, and Othmer-Tobias equation was employed for a system without salt and Eisen-Joffe equation for systems with salt to test consistency. Halogen salt solutions were prepared with aqueous solution of 5% KF, 5% NaCl, 5% NaBr and 5% NaI, respectively. Compositions of two splitting phases on liquid-liquid equilibria(L-L-E) condition were calculated and the parameters were estimated by correlating experimental tie lines with the NRTL and the UNIQUAC (or modified UNIQUAC) models. The effects of addition of four halogen salts (KF, NaCl, NaBr, NaI) to benzene-water-n-propanol system were considered.

APPLICATION OF NRTL AND UNIQUAC MODELS TO LIQUID - LIQUID SYSTEMS WITH HALOGEN SALTS(Part Ⅰ)

Choi, Joong So,Park, Dong Won,Rhim, Jin Nam 한국화학공학회 1987 Korean Journal of Chemical Engineering Vol.4 No.2