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오늘 본 자료
Yun-yun Chen,Fen-ping Cui,Fang Gu,Ying-ying Zhang 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.64 No.11
In this paper, the feasibility of using a one-temperature model to determine plasma’s temperatureby measuring its refractive index is studied based on the consideration that many plasma flow fieldsare not in local thermodynamic equilibrium (LTE). We compare the refractive indices between theone- and the two-temperature models of an arc plasma, in order to discuss the applicability ofthe one-temperature model in optical diagnosis. We found that the applicability is determined bythe pressure, the temperature ratio between electrons and heavy particles, the probe wavelength,and the chosen optical method’s refractive index measurement precision. Consequently, a commonmodel is deduced to describe the refractive index of plasma whether it be in LTE or not. In a word,this study is crucial to better apply optical methods based on measurements of the refractive indexto diagnose plasma flow fields.
Nitric Oxide Synthase 3 Gene Variants and Colorectal Cancer: a Meta-Analysis
Chen, Yang,Li, Jie,Guo, Yun,Guo, Xiao-Yun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8
Background: Colorectal cancer (CRC) is the worldwide disease which causes enormous losses every year. Recent studies suggested that environmental and gene factors might be the etiologies in increasing the risk of morbidity. Nitric oxide synthase 3 (NOS3) gene polymorphisms are said to be associated with CRC risk but the conclusion is still controversial. Materials and Methods: Pubmed and HuGENet databases up to December 2013 were used in this meta-analysis. Three different certain genotypic models were applied, namely dominant (AA+AC versus CC), recessive (AA versus AC+CC), per-allele analysis (A vs C). In addition, information on tumor sites and pathologic stages was collected. The strength of associations was assessed through combining odds ratio (OR) and 95% confidence interval (CI). Results: Finally, five and three studies about the rs1799983 and rs2070744 were covered in the analysis with 2,745 cases and 2,478 controls. Three models were applied, but no significant association was found for NOS3 G894T/rs1799983 (dominant: OR=0.999, 95%CI=0.797-1.253, $I^2$=63.8%; recessive: OR=0.924, 95%CI=0.589-1.450, $I^2$=59.3%; allele analysis: OR=0.979, 95%CI=0.788-1.216, $I^2$=74.9%) and T-786C/rs2070744 (dominant: OR=1.138, 95%CI=0.846-1.530, $I^2$=67.9%; recessive: OR=0.956, 95%CI=0.708-1.291, $I^2$=0.0%; allele analysis: OR=1.110, 95%CI=0.865-1.425, $I^2$=69.4%). The same results were also obtained for tumor sites and pathologic stage subgroups. After further analyzing the NOS3 gene, rs1799983 as the tag- and functional SNP was presented. Conclusions: On the basis of this meta-analysis and the characteristics of the NOS3 gene, we suggested rs1799983 might be a key locus associated with CRC risk. Further prospective studies were needed to make more comprehensive explanation of the associations.
Differentiation and Categorization of Strategies: From Cases in Asia
Yun-Chen Lai 미래사회통합연구센터 2019 Journal of Conflict and Integration Vol.3 No.1
The word ‘strategy’ has been widely used, but poorly defined, in the IR area. Establishing a clear definition of the term is a precondition for effective policy-making and academic research. Hence, this article aims to build a systematic framework for analyzing strategy. Based on different perception of orders, goals, and policy instruments, this paper categorizes IR strategies into five types, including revisionist, engagement, status quo, accommodative and bandwagon, providing a systematic perspective for future studies in analyzing strategy. Examples of strategies taken by actors for dealing with Asian orders are given to elucidate the characteristics of each strategy type. The comparison on various strategies of conflict and cooperation outlines the current Asian order.
[Poster Presentation] NOT ALL PAC IS SUITABLE
Chen Yun-Zhi,Xie Lai-Su 한국펄프·종이공학회 1999 한국펄프종이학회 기타 간행물 Vol.- No.-
In this paper, a series of PAC (polyaluminum chloride) samples were prepared for rosin neutral sizing system. Some characters of PAC were discussed in detail. The experimental results show that it is possible to achieve neutral sizing when PAC is compounded with DRS(dispersed rosin size)instead of alum (aluminum sulfate).
Removal of the Glycosylation of Prion Protein Provokes Apoptosis in SF126
Chen, Lan,Yang, Yang,Han, Jun,Zhang, Bao-Yun,Zhao, Lin,Nie, Kai,Wang, Xiao-Fan,Li, Feng,Gao, Chen,Dong, Xiao-Ping,Xu, Cai-Min Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.5
Although the function of cellular prion protein (PrP$^C$) and the pathogenesis of prion diseases have been widely described, the mechanisms are not fully clarified. In this study, increases of the portion of non-glycosylated prion protein deposited in the hamster brains infected with scrapie strain 263K were described. To elucidate the pathological role of glycosylation profile of PrP, wild type human PrP (HuPrP) and two genetic engineering generated non-glycosylated PrP mutants (N181Q/N197Q and T183A/T199A) were transiently expressed in human astrocytoma cell line SF126. The results revealed that expressions of non-glycosylated PrP induced significantly more apoptosis cells than that of wild type PrP. It illustrated that Bcl-2 proteins might be involved in the apoptosis pathway of non-glycosylated PrPs. Our data highlights that removal of glycosylation of prion protein provokes cells apoptosis.
Chen Yun-ze,Zhang Bo-wen,Yang Jing,Zou Chuan-shan,Li Tao,Zhang Guo-cai,Chen Guang-sheng 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.1
Carvacrol is a terpene compound with various biological activities. However, few studies have specifically focused on its insecticidal activity and mechanism of carvacrol. The larvae of Lymantria dispar are seriously harmful herbivorous insect. This study measured the antifeedant, growth-inhibitory, and toxic effects of carvacrol on L. dispar larvae. To further clarify the insecticidal mechanism of carvacrol, the effects of carvacrol on detoxifying enzymes, antioxidative enzymes, digestive enzyme activities, and the mRNA expression of the abovementioned enzyme genes were investigated. The results of the study showed that the median lethal concentration (LC 50 ) and the sublethal concentration (LC 20 ) of carvacrol were 1.120 mg/mL and 0.297 mg/mL, respectively, at 72 h. After LC 20 treatment of L. dispar larvae for 72 h, food intake and weight gain were significantly lower compared with the control. Enzyme activity assays showed that carvacrol significantly inhibited the activities of carboxylesterase (CarE), glutathione S-transferase (GST), and acetylcholinesterase (AchE), and the inhibition rate of AchE activity was highest (66.51%). Carvacrol also activated the activities of superoxide dismutase (SOD) and catalase (CAT), while it inhibited the activities of lipase (LIP) and amylase (AMS), and first inhibited and then activated protease. In addition, qRT-PCR tests showed that carvacrol affected the mRNA expression levels of CarE, GST, AchE, SOD, CAT, LIP, AMS, and protease. This study helps to clarify the insecticidal mechanism of carvacrol on L. dispar larvae.