Comprehensive In-Service Training Program to Enhance Informatics Competency for Nurses in Taiwan

Chu Li Tseng,Zu Chun Lin,Yu Chin Lee,Huea Hwa Jiang,Li Li Li,Yu Lin Han 한국간호과학회 2011 한국간호과학회 학술대회 Vol.2011 No.10

THE EVALUATION OF DECISION FACTORS IN LOGISTICS OUTSOURCING

Tseng-Cheng Lin,Wu-Yen Wen,Yu-Ling Ting 인하대학교 정석물류통상연구원 2007 인하대학교 정석물류통상연구원 학술대회 Vol.2007 No.3

Nowadays under globalize and highly sensitive market, enterprise has to clarify overall operation objective and core value in order to approach management and carve out profit opportunity. And then while appropriate logistics outsourcing method is constructed and let enterprise operation can be assisted by professional and advanced logistics service, enterprise can focus on core business more and have the best use of operation cost. This research takes Logistics Service Provider (LSP), 3rd Party Logistics (3PL) and Logistics Service Demander (LSD) as subjects. We pick 28 logistics companies among them to proceed questionnaire analysis twice. The questionnaire A uses “Likert Analysis” to find the gap on “Expectation” and “Cognitive Satisfaction” of enterprise logistics outsourcing. And then we choose the outsourcing factors under which enterprise evaluates outsourcing. The factors include four phases which are LSD, LSP, innovative technology and contract. Focusing on the enterprise outsource factors from previous questionnaire, the questionnaire B uses Analytic Hierarchy Process (AHP) to analyze the priority of each evaluation factors. And then go deep into the process of enterprise evaluating logistics outsourcing to understand how to establish reasonable and fair contract relationship and review the reason of malfunction on self-connatural core operation. According to the result of questionnaire A in our research, logistics outsourcing shows obvious differentiation between logistics practice and expectation on the items of “Improve Logistics Operation Capability”, “Enhance Logistics Performance” and “Reduce Logistics Risk Assumption”. It shows the basic outcome of logistics outsourcing still not achieve the expectation in the domain of logistics. The second, the logistics outsourcing success factors were placed according to weighting through questionnaire B. The result shows the interviewed subjects consider the top three factors that a successful logistics outsourcing has to achieve are “Assist the Growth on Enterprise Achievement”, “Enhance Logistics Performance” and “Reduce Logistics Risk Assumption”. Therefore, in order to help LSP to provide more efficient and convenient service and promote the competitiveness of native LSP, the logistics outsourcing success indication factors from this research should be improved aggressively.

Regulatory Role of cAMP Receptor Protein over Escherichia coli Fumarase Genes

Yu-Pei Chen,Hsiao-Hsien Lin,Chi-Dung Yang,Shin-Hong Huang,Ching-Ping Tseng 한국미생물학회 2012 The journal of microbiology Vol.50 No.3

Escherichia coli expresses three fumarase genes, namely, fumA, fumB, and fumC. In the present study, catabolite repression was observed in the fumA-lacZ and fumC-lacZ fusion strains, but not in the fumB-lacZ fusion strain. The Crp-binding sites in fumA and fumC were identified using an electrophoretic mobility shift assay and footprint analysis. However, the electrophoretic mobility shift assay did not detect band shifts in fumB. Fnr and ArcA serve as transcription regulators of fumarase gene expression. In relation to this, different mutants, including Δcya, Δcrp, Δfnr, and ΔarcA, were used to explore the regulatory role of Crp over fumA and fumC. The results show that Crp is an activator of fumA and fumC gene expression under various oxygen conditions and growth rates. ArcA was identified as the dominant repressor, with the major repression occurring at 0–4% oxygen. In addition, Fnr was confirmed as a repressor of fumC for the first time. This study elucidates the effects of Crp on fumarase gene expression.

Oncocytic Lipoadenoma: A Rare Case of Parotid Gland Tumor and Review of the Literature

Chen-lin Chi,Li-yu Lee,Tseng-tong Kuo 대한병리학회 2015 Journal of Pathology and Translational Medicine Vol.49 No.2

Oncocytic lipoadenoma is a rare tumor, with only 18 cases having been reported since the first in 1998. We encountered a case of oncocytic lipoadenoma presenting as a slowly growing parotid mass in a 71-year-old man. This tumor is characteristically comprised of a mixture of oncocytes and adipocytes. The present case is one of five reported cases of oncocytic lipoadenoma showing sebaceous differentiation. The results of immunohistochemical study with DOG1 antibody supported the origination of this tumor in the striated duct.

DEVELOPMENT OF AN AUXILIARY MODE POWERTRAIN FOR HYBRID ELECTRIC SCOOTER

C. Y. TSENG,C. H. YU,Y. T. LIN 한국자동차공학회 2014 International journal of automotive technology Vol.15 No.5

This paper proposes a design and implementation of an auxiliary mode, hybrid electric scooter (HES) by meansof more cost-effective way for improving scooter’s performance and efficiency. The HES is built in a parallel hybridconfiguration with a 24V 370W auxiliary power electric motor, a 24V 20AH battery, and an electronically controlled fuelinjection internal combustion engine (ICE) scooter. In contrast to hybrid electric vehicles (HEVs), the issues concerning cost,volume, and reliability are even more rigorous when developing hybrid electric scooters (HESs). Therefore, the drive topologyand control strategy used in HEV cannot be applied to HES directly. In order to hasten the developing phase and achieve theparametric tune-up of the HES component, a dynamic simulation model for the HES is developed here. Because thepowertrain system is complex and nonlinear in nature, the simulation model utilizes mathematical models in tandem withaccumulated experimental data. The method about the mathematical model construction, analysis and simulation of the hybridpowertrain used in a scooter are fully described. The efficacy of the model was verified experimentally on a scooter chassisdynamometer and the performance of the proposed hybrid powertrain is studied using the developed model under arepresentative urban driving cycle. Finally, Simulation and experimental results confirm the feasibility and prosperity of theproposed hybrid HES and indicate that the designed hybrid system can improve the fuel consumption rate up to 15%compared with the original scooter.

A Neurofeedback Protocol for Executive Function to Reduce Depression and Rumination: A Controlled Study

Sheng-Hsiang Yu,Chao-Yuan Tseng,Wei-Lun Lin 대한정신약물학회 2020 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.18 No.3

Objective: Rumination is a maladaptive emotional-regulation strategy that is strongly associated with depression. Impaired executive function can lead to difficulties in disengaging from rumination, thus exacerbating depression. In this study, we inspect an electroencephalograph neurofeedback protocol that enhance the target peak alpha frequency (PAF) activation in the prefrontal region. We examine the protocol’s effects on depression and rumination. Methods: We randomly assigned 30 dysphoric participants into either the neurofeedback training group or the control group. We then evaluated their depression, rumination, and executive function at pre- and posttraining so as to examine the effects of the neurofeedback. Results: The results show that this neurofeedback protocol can specifically enhance participants’ target PAF. The participants’ executive function performances significantly improved after undergoing 20 neurofeedback sessions. Compared with those in the control group, those in the neurofeedback group had significantly fewer depressive symptoms and significantly reduced rumination. Moreover, as target PAF and executive function improved, depression and rumination both declined. Conclusion: Our data are in line with those of previous studies that indicated a relationship between upper-band alpha activity and executive function. This PAF neurofeedback can effectively enhance participants’ executive function, which can reduce rumination and ameliorate depression. This neurofeedback training is based on basic cognitive neuroscience, so it sheds light on depression’s pathological factors and etiology

Adiabatic runaway studies for methyl ethyl ketone peroxide with inorganic acids by vent sizing package 2

Yan-Fu Lin,Jiann-Rong Chen,Jo-Ming Tseng,Shu-Yu S. Wang,Chi-Min Shu 한국화학공학회 2008 Korean Journal of Chemical Engineering Vol.25 No.3

Methyl ethyl ketone peroxide (MEKPO) is an unstable material that is classified as an explosive substance. We evaluated MEKPO 10 mass% under mixing with three inorganic acids (6 N HNO3, 6 N H3PO4, and 6 N H2SO4) by adiabatic system of vent sizing package 2 (VSP2). Results from evaluation and testing indicated that these three inorganic acids could increase the degree of hazard while combined with pure MEKPO. Therefore, information on the hazards and phenomena of runaway reaction should be provided in order to lessen the degree of hazard.

Investigating Medical Cost and Mortality Among Psychiatric Patients Involuntary Admissions: A Nationwide Propensity Score-Matched Study

Pei-Ying Tseng,Xin-Yu Xie,Ching-Chi Hsu,Sarina Hui-Lin Chien,Jen-De Chen,Jong-Yi Wang 대한신경정신의학회 2022 PSYCHIATRY INVESTIGATION Vol.19 No.7

Objective Involuntary admission to psychiatric inpatient care can protect both patients with severe mental illnesses and individuals around them. This study analyzed annual healthcare costs per person for involuntary psychiatric admission and examined categories of mental disorders and other factors associated with mortality.Methods This retrospective cohort study collected 1 million randomly sampled beneficiaries from the National Health Insurance Database for 2002–2013. It identified and matched 181 patients with involuntary psychiatric admissions (research group) with 724 patients with voluntary psychiatric admissions (control group) through 1:4 propensity-score matching for sex, age, comorbidities, mental disorder category, and index year of diagnosis.Results Mean life expectancy of patients with involuntary psychiatric admissions was 33.13 years less than the general population. Average annual healthcare costs per person for involuntary psychiatric admissions were 3.94 times higher compared with voluntary admissions. The general linear model demonstrated that average annual medical costs per person per compulsory hospitalization were 5.8 times that of voluntary hospitalization. Survival analysis using the Cox proportional hazards model found no significant association between type of psychiatric admission (involuntary or voluntary) and death.Conclusion This study revealed no significant difference in mortality between involuntary and voluntary psychiatric admissions, indicating involuntary treatment’s effectiveness.

Proton Pump Inhibitor-unresponsive Laryngeal Symptoms Are Associated With Psychological Comorbidities and Sleep Disturbance: A Manometry and Impedance-pH Monitoring Study

Wen-Hsuan Tseng,Wei-Chung Hsu,Tsung-Lin Yang,Tzu-Yu Hsiao,Jia-Feng Wu,Hui-Chuan Lee,Hsiu-Po Wang,Ming-Shiang Wu,Ming-Shiang Wu,Ping-Huei Tseng 대한소화기 기능성질환∙운동학회 2023 Journal of Neurogastroenterology and Motility (JNM Vol.29 No.3

Background/AimsLaryngeal symptoms are largely treated with empiric proton pump inhibitor (PPI) therapy if no apparent pathology shown on ear, nose, and throat evaluation and reflux-related etiologies are suspected. However, treatment response remains unsatisfactory. This study aimed to investigate the clinical and physiological characteristics of patients with PPI-refractory laryngeal symptoms. MethodsPatients with persistent laryngeal symptoms despite PPI treatment for ≥ 8 weeks were recruited. A multidisciplinary evaluation comprising validated questionnaires for laryngeal symptoms (reflux symptom index [RSI]), gastroesophageal reflux disease symptoms, psychological comorbidity (5-item brief symptom rating scale [BSRS-5]) and sleep disturbance (Pittsburgh sleep quality index [PSQI]), esophagogastroduodenoscopy, ambulatory impedance-pH monitoring, and high-resolution impedance manometry were performed. Healthy asymptomatic individuals were also recruited for comparison of psychological morbidity and sleep disturbances. ResultsNinety-seven adult patients and 48 healthy volunteers were analyzed. The patients had markedly higher prevalence of psychological distress (52.6% vs 2.1%, P < 0.001) and sleep disturbance (82.5% vs 37.5%, P < 0.001) than the healthy volunteers. There were significant correlations between RSI and BSRS-5 scores, and between RSI and PSQI scores (r = 0.26, P = 0.010, and r = 0.29, P = 0.004, respectively). Fifty-eight patients had concurrent gastroesophageal reflux disease symptoms. They had more prominent sleep disturbances (89.7% vs 71.8%, P < 0.001) than those with laryngeal symptoms alone but similar reflux profiles and esophageal motility. ConclusionsPPI-refractory laryngeal symptoms are mostly associated with psychological comorbidities and sleep disturbances. Recognition of these psychosocial comorbidities may help optimize management in these patients.

Sofosbuvir/Ledipasvir in the Treatment of Chronic Hepatitis C - A Subgroup Analysis from A Nationwide Real-World HCV Registry Program (TACR) in Taiwan

( Ming-Lung Yu ),( Chi-Yi Chen ),( Kuo-Chih Tseng ),( Ching-Chu Lo ),( Pin-Nan Cheng ),( Cheng-Yuan Peng ),( Ming-Jong Bair ),( Chih-Lang Lin ),( Chi-Ming Tai ),( Chi-Chieh Yang ),( Chih-Wen Lin ),( C 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

Aims: TASL HCV Registry (TACR) is a nationwide registry program organized and supervised by Taiwan Association for the Study of the Liver (TASL), which aims to setup the database and biobank of patients with chronic hepatitis C (CHC) in Taiwan. The present study aimed to evaluate the treatment outcome of sofosbuvir (SOF)/ledipasvir (LDV) in Taiwanese CHC patients in TACR. Methods: By May 2020, 19 tertiary hospitals, 23 community hospitals and one primary care clinic join the TACR program. The baseline characteristics, prior liver and non-liver related medical history, DAA regimens, laboratory results, treatment course and outcome were recorded. The primary objective was sustained virological response, defined as undetectable HCV RNA 3 months after end-of-treatment (SVR12). Results: A total of 4742 SOF/LDV+ ribavirin treated CHC patients with available SVR12 data from 39 sites were enrolled in the current analysis. The mean age was 61.3 years, and female accounted for 54.8% of the population. The dominant viral genotypes were GT1b (52.6%) and GT2 (35.6%). 1354 (28.6%) patients had liver cirrhosis, including 156 (3.3%) with liver decompensation, 552 (11.6%) had preexisting hepatocellular carcinoma (HCC) before DAAs treatment and 413 (8.7%) had hepatitis B virus dual infections. The overall SVR12 rate was 98.5%, with 98.5%, 98.2%, 99.7% and 98.6% in treatment- naïve non-cirrhotics, treatment-naïve cirrhotics, treatment- experienced non-cirrhotics and treatment-experienced cirrhotics patients, respectively. While patients were stratified by HCV genotype, the SVR12 was 98.5%, 98.4% and 98.5% among those with GT1, GT2 and GT6 infection, respectively. The strongest factor independent associated with treatment failure was DAA adherence < 60% (odds ratio [OR]/95% confidence intervals [CI]: 125.4/25.7-612.4, P<0.0001), followed by active HCC (OR/CI: 6.20/2.57-14.97, P<0.0001), HIV co-infection (OR/CI: 3.01/1.14-7.92, P=0.026), and male gender (OR/ CI: 1.85/1.09-3.13, P=0.023). The eGFR decreased significantly at the end of treatment (EOT) (89.3 ml/min/1.73㎡ vs. 93.2 ml/min/1.73㎡, P< 0.001) and remained stable 3 months after EOT (89.3 ml/min/1.73㎡). However, the decreased eGFR was observed only in patients whose baseline eGFR > 90 ml/ min/1.73㎡. Instead, patients with chronic kidney diseases whose pretreatment eGFR < 60 ml/min/1.73㎡ had improved eGFR after SOF/LDV. Conclusions: SOF/LDV is highly effective in treating CHC patients in real-world setting of Taiwan. The satisfactory result could be explicitly generalized to patients with different viral genotypes and liver disease severities.