http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 주제어 : Poly(ethylene glycol) grafting (검색결과 9 건)
- 무료
- 기관 내 무료
- 유료
-
정용찬,Ji Eun Park,Jae Won Choi,전병철 한국섬유공학회 2020 Fibers and polymers Vol.21 No.2
The poly(ethylene glycol) phenyl ether acrylate (PEPA) monomers are graft-polymerized onto polyurethane (PU), and its impacts on water compatibility, chain packing, tensile stress, and shape recovery capability are evaluated. The grafted poly(PEPA)s slightly increase the degree of cross-linking due to the linking between themselves. The water compatibility (water contact angle, water swelling, and water vapor permeation) are affected slightly by the grafted poly(PEPA). The grafted poly(PEPA) does not notably influence the melting of soft segments, but the crystallization of soft segments is reduced significantly. The grafted poly(PEPA) does not significantly affect the glass transition of soft segments. The grafted poly(PEPA) notably increases the breaking tensile stress with the increase in PEPA content, but the breaking tensile straindecreases slowly with increasing PEPA content. The grafted poly(PEPA) rapidly improves the shape recovery capability of PU and slowly decreases the shape retention capability with the increase in PEPA content. Therefore, the grafted poly(PEPA) slightly modifies the water compatibility but notably enhances the breaking tensile stress and shape recovery capability of PU.
-
Ko, JaeSang,Cho, Kanghee,Han, Sang Won,Sung, Hyung Kyung,Baek, Seung Woon,Koh, Won-Gun,Yoon, Jin Sook Elsevier 2017 Colloids and surfaces Biointerfaces Vol.158 No.-
<P><B>Abstract</B></P> <P>Ocular prostheses are custom-made polymeric inserts that can be placed in anophthalmic sockets for cosmetic rehabilitation. Prosthetic eye wearers have reduced tear amount, and they often experience dry eye symptoms including dryness, irritation, discomfort, and discharge. Most modern ocular prostheses are made of poly(methyl methacrylate) (PMMA), which is highly hydrophobic. Previous research has shown that improving the wettability of contact lens materials decreases its wearers discomfort by increasing lubrication. Therefore, hydrophilic modification of PMMA-based ocular prostheses might also improve patient discomfort by improving lubrication. We modified the surfaces of PMMA-based ocular prostheses using poly(ethylene glycol) (PEG), which is hydrophilic. To do this, we used two strategies. One was a “grafting from” method, whereby PEG was polymerized from the PMMA surface. The other was a “grafting to” method, which involved PEG being covalently bonded to an amine-functionalized PMMA surface. Assessments involving the water contact angle, ellipsometry, and X-ray photoelectron spectroscopy indicated that PEG was successfully introduced to the PMMA surfaces using both strategies. Scanning electron microscopy and atomic force microscopy images revealed that neither strategy caused clinically significant alterations in the PMMA surface morphology. In vitro bacterial adhesion assessments showed that the hydrophilic modifications effectively reduced bacterial adhesion without inducing cytotoxicity. These results imply that hydrophilic surface modifications of conventional ocular prostheses may decrease patient discomfort and ocular prosthesis-related infections.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Surfaces of PMMA-based ocular prosthesis were modified via PEG grafting. </LI> <LI> The hydrophilic surface modifications effectively inhibited bacterial adhesion. </LI> <LI> These modifications of ocular prostheses may decrease discomfort and infections. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
-
고원건,Woojin Lee,Tae Gyu Lee 한국공업화학회 2007 Journal of Industrial and Engineering Chemistry Vol.13 No.7
The modification of the protein-repellent poly(ethylene glycol) (PEG) hydrogel surface was achieved by a two-step process using immobilization of benzophenone on the PEG hydrogel as surface initiator and subsequent surface-initiated graft polymerization of acrylic acid by UV irradiation. Formation of poly(acrylic acid) (PAA) layer on the PEG hydrogel was demonstrated by confirming the presence of carboxyl groups in the poly(acrylic acid) (PAA) with FTIR/ATR spectroscopy and measuring the height of PAA layers with alpha-step surface profiler. In the grafted region, PAA and PEG hydrogel formed an interpenetrating polymer network extending 200 m into PEG hydrogel and homo PAA protruded 14∼17 m above the PEG hydrogel surface. Activation of the carboxyl groups in PAA allowed covalent immobilization of collagen, a cell adhesion protein, on the PAA-grafted PEG hydrogel, which was demonstrated with FTIR/ATR spectroscopy by confirming the formation of a new amide bond. Surface-initiated graft polymerization combined with photolithography produced well-defined PAA micropatterns on the PEG hydrogels and collagen was immobilized only on the PAA region due to the lack of adhesion for proteins to PEG, producing protein micropattern on the PEG hydrogel.
-
Son, Kyung Jin,Ahn, Sung Hoon,Kim, Jong Hak,Koh, Won-Gun American Chemical Society 2011 ACS APPLIED MATERIALS & INTERFACES Vol.3 No.2
<P>In this study, we describe the use of organized mesoporous titanium oxide (TiO<SUB>2</SUB>) films as three-dimensional templates for protein microarrays with enhanced protein loading capacity and detection sensitivity. Multilayered mesoporous TiO<SUB>2</SUB> films with high porosity and good connectivity were synthesized using a graft copolymer consisting of a poly(vinyl chloride) (PVC) backbone and poly(oxyethylene methacrylate) (POEM) side chains as a structure-directing template. The average pore size and thickness of the TiO<SUB>2</SUB> films were 50-70 nm and 1.5 μm, respectively. Proteins were covalently immobilized onto mesoporous TiO<SUB>2</SUB> film via 3-aminopropyltriethoxysilane (APTES), and protein loading onto TiO<SUB>2</SUB> films was about four times greater than on planar glass substrates, which consequently improved the protein activity. Micropatterned mesoporous TiO<SUB>2</SUB> substrates were prepared by fabricating poly(ethylene glycol) (PEG) hydrogel microstructures on TiO<SUB>2</SUB> films using photolithography. Because of non-adhesiveness of PEG hydrogel towards proteins, proteins were selectively immobilized onto surface-modified mesoporous TiO<SUB>2</SUB> region, creating protein microarray. Specific binding assay between streptavidin/biotin and between PSA/anti-PSA demonstrated that the mesoporous TiO<SUB>2</SUB>-based protein microarrays yielded higher fluorescence signals and were more sensitive with lower detection limits than microarrays based on planar glass slides.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2011/aamick.2011.3.issue-2/am101141z/production/images/medium/am-2010-01141z_0011.gif'></P>
-
감마선 조사를 이용하여 Poly(ethylene glycol) Methacrylate가그래프팅된 케냐프 섬유를 포함하는 시멘트복합재료의 제조
이병민,강필현,전준표 한국방사선산업학회 2014 방사선산업학회지 Vol.8 No.1
Kenaf fibers have excellent properties and possess the potential to be outstandingreinforcing fillers in cement. The grafting of poly(ethylene glycol) methacrylate (PEGMA) to thekenaf fibers is important in improving the compatibility between the fibers and the cement. PEGMA was grafted onto kenaf fibers using gamma-ray radiation. The radiation dose rangedfrom 20 to 60 kGy, and the dose rate was 10 kGy h-1. The degree of grafting increased withincreased radiation doses. FT-IR analysis revealed an increase in PEGMA content after gammarayradiation induced grafting, further evincing the attachment of PEGMA to the kenaf fibers. The mechanical properties of the gamma-ray grafted kenaf fiber/cement composites weresuperior to those of the ungrafted kenaf fiber/cement specimens.
-
-
감마선을 이용한 케나프 펄프 표면의 Poly(ethylene glycol) Methacrylate 그라프트 중합반응
오두리,전준표,강필현 한국방사선산업학회 2012 방사선산업학회지 Vol.6 No.3
Pulp is typically used for paper industry to manufacturing various types of papers. Howeversimply chemical modification makes enable the pulp to a wide range of application in variousindustrial fields. To bring the polymerization the gamma ray irradiated on the mixture of kenafand PEGMA in various dose ranges from 20 to 60 kGy. As a results, the graft degree of 20.0% wasobtained from 475 g of gamma ray irradiated pulp and PEGMA. After the polymerization, the chemicalstructure and morphology of the surfaces were examined by Fourier transform infrared spectroscopy,thermogravimetric analysis, and scanning electron microscope. Chemical structure ofgrafted pulp has significantly growth in carbonyl content with increasing the radiation dose. Alsosurface morphology was distinctly changed with decreased the degree of roughness and increasingthe diameter. These results were explained gamma ray irradiation improve performance of graftpolymerization efficiency.
-
-
Kim, You-Kyoung,Minai-Tehrani, Arash,Lee, Jae-Ho,Cho, Chong-Su,Cho, Myung-Haing,Jiang, Hu-Lin Dove Medical Press 2013 International journal of nanomedicine Vol.8 No.-
<P><B>Background</B></P><P>Chitosan and chitosan derivatives have been proposed as alternative and biocompatible cationic polymers for nonviral gene delivery. However, the low transfection efficiency and low specificity of chitosan is an aspect of this approach that must be addressed prior to any clinical application. In the present study, folated poly(ethylene glycol)-chitosan-graft-polyethylenimine (FPCP) was investigated as a potential folate receptor-overexpressed cancer cell targeting gene carrier.</P><P><B>Methods</B></P><P>The FPCP copolymer was synthesized in two steps. In the first step, folate-PEG was synthesized by an amide formation reaction between the activated carboxyl groups of folic acid and the amine groups of bifunctional poly(ethylene glycol) (PEG). In the second step, FPCP was synthesized by an amide formation reaction between the activated carboxyl groups of folate-PEG and amine groups of CHI-g-polyethyleneimine (PEI). The composition of FPCP was characterized by 1H nuclear magnetic resonance.</P><P><B>Results:</B></P><P>FPCP showed low cytotoxicity in various cell lines, and FPCP-DNA complexes showed good cancer cell specificity as well as good transfection efficiency in the presence of serum. Further, FPCP-<I>Pdcd4</I> complexes reduced tumor numbers and progression more effectively than PEI 25 kDa in H-<I>ras</I>12V liver cancer mice after intravenous administration.</P><P><B>Conclusion</B></P><P>Our data suggest that FPCP, which has improved transfection efficiency and cancer cell specificity, may be useful in gene therapy for liver cancer.</P>
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
