Clinicodermoscopic features of atypical dermatofibroma compared with typical type

( Haneul Oh ),( Tae Jun Park ),( Bo Young Kim ),( Chang Min Kim ),( Hwa Jung Ryu ),( Hye Rim Moon ),( Il-hwan Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Dermatofibroma is a common benign skin neoplasm that is usually easy to recognize, but in some cases its differentiation from atypical dermatofibroma may be difficult. Objectives: To describe the clinical and dermoscopic features of atypical dermatofibromas and to differentiate from typical type according to the above features. Methods: We retrospectively searched the database of patients from Korea University Ansan Hospital from January 2010 to July 2018, who had skin biopsy or excision operation with the resulting pathology report of typical and atypical dermatofibroma. Analysis of the clinical demographics (age, gender, anatomical site etc.) and dermoscopic features was done. Results: Of the 240 patients diagnosed with dermatofibroma, 19 (7.9%) were identified as atypical deramtofibroma. In comparison of clinical features, the atypical type was not significantly different from the typical type. However, dermoscopy findings of four patients with atypical dermatofibroma were analyzed, and These dermoscopic findings are patterns that appear below 6% in typical types. Conclusion: Atypical dermatofibroma is clinically difficult to distinguish from the typical counterpart and biopsy is essential for diagnosis. If dermatofibroma is suspected and exhibits rare dermoscopy findings, it may be an atypical type and should be treated with caution when treating because of the tendency to recur and metastasis.

비정형 치통 및 삼차 신경통 환자의 임상 특징과 치료 반응의 관계

최서영,정성희,주혜민,옥수민,안용우 대한노년치의학회 2022 대한노년치의학회지 Vol.18 No.1

Unexplained toothache is likely to be neuralgia that appears in the teeth. Atypical odontalgia(AO) and trigeminal neuralgia(TN), which are commonly seen in types of neuralgia, can be distinguished by identifying their clinical characteristics. The purpose of this study is to provide information for differential diagnosis by analyzing clinical features of patients suffering from these two diseases. From 2013 to 2022, medical records of 124 patients diagnosed with AO or TN who visited the Department of Oral Medicine at Pusan National University Dental Hospital were analyzed. Analysis was performed on 12 factors related to the patient’s clinical features. Patients with AO are generally younger than those with TN, and few patients show complete improvement (p<0.05). Compared to TN patients who showed sharp pain, AO patients mainly complained of dull pain, which lasted all day (p<0.05). In both diseases, unilateral pain predominantly appeared and the appearance of increased pain during contact stimulation was higher in patients with TN (p<0.05).Patients with AO often developed symptoms after dental treatment and responded relatively well to antidepressants. In contrast, TN patients were less associated with dental treatment, and antiepileptic drugs could reduce pain. In conclusion, the age of patients, pain duration, increased pain to stimulation, pain related to dental treatment, and type of medication indicating the therapeutic effect are important factors that differentiate between AO and TN.

[P046] Erythema multiforme with atypical clinical features

( Jeong Won Jo ),( Young Bin Shin ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Erythema multiforme (EM) is a hypersensitivity reaction characterized by targetoid skin lesions with or without erosions of mucosal surfaces. An acute, self-limiting or episodic course and the presence of targetoid lesions, raised atypical papules or mucosal involvement, are the important clues to diagnose with EM. Laboratory studies and skin biopsies are not required in all cases of EM. EM has been classified into a number of variants, mainly minor and major forms. In the case of general EM major, the mucosal lesions as well as the cutaneous lesions are also more severe and cover a wide range of skin surface. However, we examined a case of EM with atypical clinical features. Unlike general EM major, the cutaneous lesions of our patient were mild and limited to hands and feet that uncommonly involved, although the erosive lesions of oral and genital mucosa were severe. This atypical feature caused misdiagnosis to hand, foot and mouth disease and led to delay proper treatment. In conclusion, we should be recognized that there is a case of EM with atypical clinical features and refer to it when diagnosing.

Magnetic Resonance Image Manifestations of the Atypical Meningioma

Wu, Qing-Wu,Yan, Rui-Fang,Li, Qiang,Hu, Ying,Zhou, Feng-Mei,Ren, Ji-Peng,Yang, Rui-Min,Zhang, Yan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

Through retrospective analysis of 13 cases of magnetic resonance image (MRI) manifestations of atypical meningiomas confirmed by operation and pathology in the First Affiliated Hospital of Xinxiang Medical University, the objective of this study was to evaluate the diagnostic value of MRI in order to improve the accuracy rate of preoperative diagnosis. In this retrospective analysis of MRI findings for atypical meningiomas in First Affiliated Hospital of Xinxiang Medical University from January to July in 2012, the location, morphology and tumor signals and other tumor imaging characteristics were covered. In 13 cases of atypical meningioma patients of this group, most tumors were located at typical sites (10/13), mainly the falx cerebri, parasagittal, convexity, saddle area. Only two cases were at atypical locations, 1 in the cerebellar hemisphere and 1 in a lateral ventricle. Most of the tumors showed T1 and T2 isointensity signals, and necrosis, calcification, and peritumoral edema were always featured. DWI showed isointensity in 11 cases (11/13), and hyperintensity in 2. Some 9 cases had dural tail signs, 12 had accurate positioning (12/13), and 2 were postoperative recurrences. MRI has high value in the diagnosis of atypical meningiomas, with important roles in early clinical diagnosis, treatment and prognosis evaluation.

비전형적 대퇴골 골절의 역학 및 임상적 특성

이영균(Young-Kyun Lee),윤병호(Byung-Ho Yoon),구경회(Kyung-Hoi Koo) 대한정형외과학회 2013 대한정형외과학회지 Vol.48 No.3

비전형적 대퇴골 골절은 전형적 대퇴골 골절과 달리 전자 하부나 간부에 발생하는 골절로, 소전자 직하부에서부터 과상부 직상부까지 부위에 외상이 없거나 경미한 외상으로 수평 혹은 짧은 사선 골절의 형태로 분쇄 골편 없이 완전 또는 불완전 골절(외측 피질골만 침범)을 특징으로 한다. 여러 연구들이 장기간 비스포스포네이트 사용과 비전형적 대퇴골 골절의 연관성을 보고하고 있으나 비전형적 대퇴골 골절의 발생 빈도가 매우 낮아 아직까지 직접적인 연관성에 대해서는 논란의 여지가 많은 상태이다. 본 연구에서는 비전형적 대퇴골 골절에 대한 역학과 장기간 비스포스포네이트의 사용과 관련한 고찰, 그리고 비전형적 대퇴골 골절의 임상적 특징에 대해 살펴보고자 한다. Atypical femoral fractures occur at the subtrochanteric or diaphyseal area, unlike typical hip fractures. Characteristics of atypical femoral fractures include their location in the subtrochanteric region and the femoral shaft, transverse or short oblique orientation, minimal or no associated trauma, a medial spike when the fracture is complete, and absence of comminution. The incidence of atypical femoral fracture is very low, and several studies have reported statistically significant association of long-term bisphosphonate therapy with atypical femoral shaft fractures; however, this has not been proven. We review the epidemiology and clinical features of atypical femoral fracture in the literature, and also discuss the association between atypical femoral fracture and long-term use of bisphosphonate.

한국인 성인 급성 A형 간염의 임상 양상

이상구 ( Sang goo Lee ),이준혁 ( Joon Hyoek Lee ),백승운 ( Seung Woon Paik ),고광철 ( Kwang Cheul Koh ),최문석 ( Moon seok Choi ),이풍렬 ( Poong Lyul Rhee ),김재준 ( Jae Jun Kim ),이종철 ( Jong Chul Rhee ),최규완 ( Kyoo Wan Cho 대한내과학회 1999 대한내과학회지 Vol.56 No.6

Objective : This study was aimed to characterize the clinical features and course of acute hepatitis A in Korean adults. Methods : One-hundred and thirteen cases of acute hepatitis A, diagnosed between Jan. 1995 to July 1998 at 6 medical centers in Korea, were reviewed retrospectively. The clinical course of 94 cases with follow-up duration longer than 3 months were analyzed. Results : The median age was 26 (16-65) years and 97.3% of the patients were under 40 years. The presumed sources of infection were identifed in 62 cases (54.9%). Among those, the leading source was ingestion of raw food. All patients showed normalization of bilirubin level within 8 weeks. The ALT levels normalized within 8 weeks in all patients except three patients (3.2%). Three patients with prolonged elevation of ALT showed second rise of ALT, suggesting a possibility of relapsing hepatitis. Prolonged fever (>38℃) more than 10 days was observed in 3 patients (3.2%). One case showed prolonged elevation of alkaline phosphatase (> x3 upper normal limit). No case of fulminant hepatic failure or death was observed. Conclusion : The majority of cases with acute hepatitis A in Korean adults showed self-limited course with full recovery.