IMPROVED PERTURBATION BOUND FOR ROBUST STABILITY IN LINEAR SYSTEM

Zhang Zhao,Zhao Chan Gan,Hu Heng Zhang 대한전자공학회 1992 대한전자공학회 Conference Vol.1992 No.2

Clinical Reference Strategy for the Selection of Treatment Materials for Maxillofacial Bone Transplantation: A Systematic Review and Network Meta-Analysis

Zhang Shuxin,Zhang Xinyi,Li Yanling,Mao Xuran,Liu Rui,Qi Yanxin,Lee Eui-Seok,Jiang Heng Bo 한국조직공학과 재생의학회 2022 조직공학과 재생의학 Vol.19 No.3

Bone graft materials have mixed effects of bone repair in the field of oral maxillofacial surgery. The qualitative analyses performed by previous studies imply that autogenous odontogenic materials and autogenous bone have similar effects on bone repair in clinical jaw bone transplantation. This retrospective systematic assessment and network meta-analysis aimed to analyze the best effect of clinical application of autogenous odontogenic materials and autogenous, allogeneic, and xenogeneic bone grafts in bone defect repair. A systematic review was performed by searching the PubMed, Cochrane Library, and other journal databases using selected keywords and Medical Subject Headings search terms. 10 Papers (n = 466) that met the inclusion criteria were selected. The assessment of heterogeneity did not reveal any overall statistical difference or heterogeneity (P = 0.051 > 0.05), whereas the comparison between autogenous and allogeneic bone grafts revealed local heterogeneity (P = 0.071 < 0.1). Risk of bias revealed nine unclear studies and one high-risk study. The overall consistency was good (P = 0.065 > 0.05), and the local inconsistency test did not reveal any inconsistency. The publication bias was good. The confidence regarding the ranking of bone graft materials after GRADE classification was moderate. The effects on bone repair in the descending order were as follows: autogenous odontogenic materials, xenogeneic bone, autogenous bone, and allogeneic bone. This result indicates that the autogenous odontogenic materials displayed stronger effects on bone repair compared to other bone graft materials. Autogenous odontogenic materials have broad development prospects in oral maxillofacial surgery.

Amorphous Materials : THE FORMATION ABILITY AND THERMAL PROPERTIES OF Cu - P BASED AMORPHOUS ALLOYS

Zhang Bangwei,Shu Xiaolin,Tan Zhaosheng,Zhang Heng 대한금속재료학회 ( 구 대한금속학회 ) 1995 Advanced Material and Processing Vol.2 No.-

Expression and Clinical Significance of REPS2 in Human Esophageal Squamous Cell Carcinoma

Zhang, Hang,Duan, Chao-Jun,Zhang, Heng,Cheng, Yuan-Da,Zhang, Chun-Fang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

Objective: REPS2 plays important roles in inhibiting cell proliferation, migration and in inducing apoptosis of cancer cells, now being identified as a useful biomarker for favorable prognosis in prostate and breast cancers. The purpose of this study was to assess REPS2 expression and to explore its role in esophageal squamous cell carcinoma (ESCC). Methods: Protein expression of REPS2 in ESCCs and adjacent non-cancerous tissues from 120 patients was analyzed by immunohistochemistry and correlated with clinicopathological parameters and patient outcome. Additionally, thirty paired ESCC tissues and four ESCC cell lines and one normal human esophageal epithelial cell line were evaluated for REPS2 mRNA and protein expression levels by quantitative RT-PCR and Western blotting. Results: REPS2 mRNA and protein expression levels were down-regulated in ESCC tissues and cell lines. Low protein levels were significantly associated with primary tumour, TNM stage, lymph node metastasis and recurrence (all, P < 0.05). Survival analysis demonstrated that decreased REPS2 expression was significantly associated with shorter overall survival and disease-free survival (both, P < 0.001), especially in early stage ESCC patients. When REPS2 expression and lymph node metastasis status were combined, patients with low REPS2 expression/lymph node (+) had both poorer overall and disease-free survival than others (both, P < 0.001). Cox multivariate regression analysis further revealed REPS2 to be an independent prognostic factor for ESCC patients. Conclusions: Our findings demonstrate that downregulation of REPS2 may contribute to malignant progression of ESCC and represent a novel prognostic marker and a potential therapeutic target for ESCC patients.

A Green Deep Eutectic Solvent-Based Ultrasound-Assisted Method to Extract Astaxanthin from Shrimp Byproducts

Zhang, Heng,Tang, Baokun,Row, Kyung Ho Taylor Francis 2014 Analytical letters Vol.47 No.5

An Improved Secure Semi-fragile Watermarking Based on LBP and Arnold Transform

Zhang, Heng,Wang, Chengyou,Zhou, Xiao Korea Information Processing Society 2017 Journal of information processing systems Vol.13 No.5

In this paper, we analyze a recently proposed semi-fragile watermarking scheme based on local binary pattern (LBP) operators, and note that it has a fundamental flaw in the design. In this work, a binary watermark is embedded into image blocks by modifying the neighborhood pixels according to the LBP pattern. However, different image blocks might have the same LBP pattern, which can lead to false detection in watermark extraction process. In other words, one can modify the host image intentionally without affecting its watermark message. In addition, there is no encryption process before watermark embedding, which brings another potential security problem. To illustrate its weakness, two special copy-paste attacks are proposed in this paper, and several experiments are conducted to prove the effectiveness of these attacks. To solve these problems, an improved semi-fragile watermarking based on LBP operators is presented. In watermark embedding process, the central pixel value of each block is taken into account and Arnold transform is adopted to guarantee the security of watermark. Experimental results show that the improved watermarking scheme can overcome the above defects and locate the tampered region effectively.

Fragile Watermarking Based on LBP for Blind Tamper Detection in Images

Zhang, Heng,Wang, Chengyou,Zhou, Xiao Korea Information Processing Society 2017 Journal of information processing systems Vol.13 No.2

Nowadays, with the development of signal processing technique, the protection to the integrity and authenticity of images has become a topic of great concern. A blind image authentication technology with high tamper detection accuracy for different common attacks is urgently needed. In this paper, an improved fragile watermarking method based on local binary pattern (LBP) is presented for blind tamper location in images. In this method, a binary watermark is generated by LBP operator which is often utilized in face identification and texture analysis. In order to guarantee the safety of the proposed algorithm, Arnold transform and logistic map are used to scramble the authentication watermark. Then, the least significant bits (LSBs) of original pixels are substituted by the encrypted watermark. Since the authentication data is constructed from the image itself, no original image is needed in tamper detection. The LBP map of watermarked image is compared to the extracted authentication data to determine whether it is tampered or not. In comparison with other state-of-the-art schemes, various experiments prove that the proposed algorithm achieves better performance in forgery detection and location for baleful attacks.

Pragmatic Understanding of Linguistic Landscape: A Relevance-Theoretic Perspective

Heng Zhang,이상철 한국언어연구학회 2019 언어학연구 Vol.24 No.3

This study aims to decipher linguistic landscape from a relevance-theoretic perspective in the hope of further broadening the exploration of linguistic landscape research. Relevance theory (Sperber & Wilson, 1986/1995) is incorporated to answer three questions: (1) Why do viewers focus on linguistic landscape? (2) What is the cognitive mechanism when viewers noticing linguistic landscape? (3) How do viewers identify the intended meanings of linguistic landscape? The analysis uncovers that attention paid to linguistic landscape is on the grounds that it is an input relevant to the mentally represented assumptions of the addressers and exerts a “positive cognitive effect” (Sperber & Wilson 1995, §3.1–2) in a context which may strengthen, revise or yield implications of an existing assumption on one hand. On the other hand, in light of optimal relevance, the relevance-guided comprehension heuristic can be utilized by the viewers as a sound approach to identify the communicator's meaning of linguistic landscape.

Semantic transparency of noun-noun compounds in Chinese and English: A case of ‘ji(机)’ and ‘machine’

ZHANG HENG,이상철 한국언어연구학회 2020 언어학연구 Vol.25 No.2

This case study examined the degree of the perceived semantic transparency of noun-noun compounds with the same word family: Chinese 'ji(机)' and its English equivalence 'machine'. The result indicated that compounds with ’machine‘ right-headed were dominant in number compared with the left-headed ones while compounds with ’ji(机)’ in both positions maintained opacity. It is argued that the naming of the new creations or inventions brought about more semantically transparent noun-noun compounds in English. By contrast, the stability and limitedness of Chinese characters facilitated the meaning extension or shift in compounding, thus making the Chinese noun-noun compounds more semantically opaque via metonymy and metaphor.

GATA2-Mediated Transcriptional Activation of Notch3 Promotes Pancreatic Cancer Liver Metastasis

Heng Lin,Peng Hu,Hongyu Zhang,Yong Deng,Zhiqing Yang,Leida Zhang 한국분자세포생물학회 2022 Molecules and cells Vol.45 No.5

The liver is the predominant metastatic site for pancreatic cancer. However, the factors that determine the liver metastasis and the specific molecular mechanisms are still unclear. In this study, we used human pancreatic cancer cell line Hs766T to establish Hs766T-L3, a subline of Hs766T with stable liver metastatic ability. We performed RNA sequencing of Hs766T-L3 and its parental cell line Hs766T, and revealed huge differences in gene expression patterns and pathway activation between these two cell lines. We correlated the difference in pathway activation with the expression of the four core transcriptional factors including STAT1, NR2F2, GATA2, and SMAD4. Using the TCGA database, we examined the relative expression of these transcription factors (TFs) in pan-cancer and their relationship with the prognosis of the pancreatic cancer. Among these TFs, we considered GATA2 is closely involved in tumor metastasis and may serve as a potential metastatic driver. Further in vitro and in vivo experiments confirmed that GATA2-mediated transcriptional activation of Notch3 promotes the liver metastasis of Hs766T-L3, and knockdown of either GATA2 or Notch3 reduces the metastatic ability of Hs766T-L3. Therefore, we claim that GATA2 may serve as a metastatic driver of pancreatic cancer and a potential therapeutic target to treat liver metastasis of pancreatic cancer.