CONTRIBUTIONS OF OVERSEAS R&D SUBSIDIARIES TO HEADQUARTER INNOVATION PERFORMANCE: THE MODERATING ROLE OF THE EXTERNAL EMBEDDEDNESS AND ABSORPTIVE CAPACITY

Yura Jung,Chul Lee,Jina Kang 글로벌지식마케팅경영학회 2017 Global Fashion Management Conference Vol.2017 No.07

Overseas R&D subsidiaries contribute to the cross -border knowledge sourcing of MNC headquarter by providing tacit and context specific knowledge and reducing the searching cost of the headquarter

Contributions of Overseas R&D Subsidiaries on Headquarters Innovation Performance: The Moderating Roles of Social Embeddedness and Knowledge Digestibility

Yura Jung(정유라),Chul Lee(이철),Jina Kang(강진아) 연세대학교 경영연구소 2020 연세경영연구 Vol.57 No.2

다국적 기업의 해외 연구개발 지사는 본사에 암묵지적이고 사회적 맥락에 대한 이해에 기반한 지식을 제공함으로써 본사의 효율적인 현지국 지식 습득과 학습에 기여한다. 본 연구는 어떻게 해외 연구개발 지사가 본사로 하여금 해당국의 지역적인 지식을 효율적으로 소싱하고 그로부터 학습하게 도와주는지를 밝히고자 한다. 연구는 또한 현지국의 기업들과 제휴를 맺음으로써 형성되는 해외 연구개발지사의 외부적 배태성이 이후에 본사의 해외지식 습득과 활용에 미치는 영향에 미치는 효과를 규명한다. 뿐만 아니라, 다국적 기업본사가 해외 연구개발지사에 비하여 지식 소화성을 갖추고 있는 것이 본사의 해당국 지식습득과 학습을 용이하게 하는 해외 연구개발 지사의 역할을 더욱 증폭시켜주는 조건임을 제시한다. 본 연구는 2008년 Fortune 500 기업 리스트에 속하는 162개의 다국적 기업들의 해외 연구개발 지사의 지리적 분포에 관한 데이터와 각각의 다국적 기업의 특허 데이터, 제휴 데이터 및 재무 데이터에 기반하여 정립한 가설을 검증하였다. 결과를 통해 다국적 기업의 본사가 해외 연구개발 지사가 지식이 풍부한 해당국에 존재함으로써 이후의 해당국 지식 습득과 학습에 관련한 일련의 활동에 있어 혜택을 볼 수 있음을 확인하였다. 또한, 결과는 본사가 지식 소화성을 갖추는 것이 이후 본사의 이후 혁신 성과에 해당국가의 연구개발지사가 기여하게 되는 바를 더욱 증폭시킴을 확인하였다. Overseas R&D subsidiaries contribute to the cross-border knowledge sourcing of multinational corporation (MNC) headquarters by providing tacit and context-specific knowledge and reducing the search costs borne by the headquarters. This study examines how overseas R&D subsidiaries allow their headquarters to source local knowledge from the host country in an efficient way. The study also investigates the effect on overseas knowledge sourcing which derives from the external embeddedness of an overseas R&D subsidiary in the local network of the host country upon experiencing the alliance with local entities. In addition, the degree of knowledge digestibility that each headquarters retains as a condition by which host country knowledge sourcing of headquarters can be effectively facilitated by the host country R&D subsidiary is also investigated. The study tests the hypotheses established with the data of geographical distribution of overseas R&D subsidiaries of 162 multinationals which were included on the Fortune 500 MNC list in the year 2008 and the patent data of each firm along with the alliance and financial data. The study provides empirical evidence that the headquarters can benefit from the existence of a R&D subsidiary when it exists in a host country with abundant knowledge. Moreover, the findings suggest that the headquarters having a degree of knowledge digestibility will reinforce the role of host country R&D subsidiary on host country knowledge acquisition, learning, and innovation of the headquarters.

Determination of Thiamine in Pharmaceutical Preparations by Reverse Phase Liquid Chromatography Without Use of Organic Solvent

서준혁,Jung-Hyun Kim,Juhee Jung,Kyunghyun Kim,Seul Gi Lee,Hyun-Deok Cho,Yura Jung,한상범 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.6

A novel green aqueous mobile phase modified with room temperature ionic liquids (RTILs) was employed in the absence of volatile organic solvents or ion-pairing reagents to analyze thiamine, a very polar compound, by reverse phase high performance liquid chromatography (RP-HPLC). Due to its strongly hydrophilic nature, thiamine was eluted near the column dead time (t0) using a mobile phase without adding RTILs or ion-pairing reagents, even if a 100% aqueous mobile phase, which has weak elution power under reverse phase conditions, was used. Thus, 1-ethyl-3-methyl-imidazolium hexafluorophosphate ([EMIM][PF6]), which has the strongest chaotropic effect, was selected as a mobile phase additive to improve retention and avoid baseline disturbances at t0. Various mobile phase parameters such as cation moiety, chaotropic anion moiety, pH and concentration of RTILs were optimized to determine thiamine at the proper retention time. Method validation was performed to assess linearity, intra- and inter-day accuracy and precision, recovery and repeatability; all results were found to be satisfactory. The developed method was also compared to the current official United States Pharmacopoeia (USP) and Korean Pharmacopoeia (KP) methods using an organic mobile phase containing an ionpairing reagent by means of evaluating various chromatographic parameters such as the capacity factor, theoretical plate number, peak asymmetry and tailing factor. The results indicated that the proposed method exhibited better efficiency of thiamine analysis than the official methods, and it was successfully applied to quantify thiamine in pharmaceutical preparations.

Prognostic Implication of Right Ventricle Parameters Measured on Preoperative Cardiac MRI in Patients with Functional Tricuspid Regurgitation

Ahn Yura,Koo Hyun Jung,Kang Joon-Won,Choi Won Jin,Kim Dae-Hee,Song Jong-Min,Kang Duk-Hyun,Song Jae-Kwan,Kim Joon Bum,Jung Sung-Ho,Choo Suk Jung,Chung Cheol Hyun,Lee Jae Won,Yang Dong Hyun 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.8

Objective: To investigate the prognostic value of preoperative cardiac magnetic resonance imaging (MRI) for long-term major adverse cardiac and cerebrovascular events (MACCEs) in patients undergoing tricuspid valve (TV) surgery for functional tricuspid regurgitation (TR). Materials and Methods: The preoperative cardiac MR images, New York Heart Association functional class, comorbidities, and clinical events of 78 patients (median [interquartile range], 59 [51–66.3] years, 28.2% male) who underwent TV surgery for functional TR were comprehensively reviewed. Cox proportional hazards analyses were performed to assess the associations of clinical and imaging parameters with MACCEs and all-cause mortality. Results: For the median follow-up duration of 5.4 years (interquartile range, 1.2–6.6), MACCEs and all-cause mortality were 51.3% and 23.1%, respectively. The right ventricular (RV) end-systolic volume index (ESVI) and the systolic RV mass index (RVMI) were higher in patients with MACCEs than those without them (77 vs. 68 mL/m2, p = 0.048; 23.5 vs. 18.0%, p = 0.011, respectively). A high RV ESVI was associated with all-cause mortality (hazard ratio [HR] per value of 10 higher ESVI = 1.10, p = 0.03). A high RVMI was also associated with all-cause mortality (HR per increase of 5 mL/m2 RVMI = 1.75, p < 0.001). After adjusting for age and sex, only RVMI remained a significant predictor of MACCEs and all-cause mortality (p < 0.05 for both). After adjusting for multiple clinical variables, RVMI remained significantly associated with all-cause mortality (p = 0.005). Conclusion: RVMI measured on preoperative cardiac MRI was an independent predictor of long-term outcomes in patients who underwent TV surgery for functional TR.

취약성 자기애가 자기침묵에 미치는 영향: 실제-이상 자기불일치와 수치심의 매개효과

정유라 ( Yura Jung ) 한국심리유형학회 2019 심리유형과 인간발달 Vol.20 No.1

본 연구는 취약성 자기애와 자기침묵의 관계에서 실제-이상 자기불일치와 수치심의 매개 역할을 검증하고자 하였다. 이를 위해 성인 451명을 대상으로 병리적 자기애 척도, 자기 질문지, 수치심 경험 척도, 자기침묵 척도를 실시하여 자료를 수집하였으며, 이들 변인 간의 관계에 대한 가설적인 구조방정식모형을 설정하고 검증하였다. 이에 대한 결과는 다음과 같다. 첫째, 취약성 자기애가 자기침묵에 미치는 영향을 실제-이상 자기불일치가 부분적으로 매개하였다. 둘째, 취약성 자기애가 자기침묵에 미치는 영향을 수치심이 부분적으로 매개하였다. 셋째, 취약성 자기애가 자기침묵에 미치는 영향을 실제-이상자기불일치와 수치심이 순차적으로 부분매개하였다. 이러한 연구결과는 취약성 자기애를 지닌 개인이 대인관계에서 이상과 괴리된 실제 자신의 모습을 감추고, 수치심으로부터 자기(self)를 보호하기 위하여 자신의 생각과 감정을 감추는 방식으로 행동하는 자기침묵 경향이 있음을 보여준다. 본 연구의 의의 및 제한점, 후속 연구를 위한 제언을 논의에 포함하였다. The purpose of this study is to examine the mediating roles of actual-ideal self discrepancy and shame in relationship between vulnerable narcissism and self-silencing. 451 undergraduate students responded to the scales of pathological narcissism(Pathological Narcissism Inventory; PNI), self-silencing(Silencing The Self Scale; STSS), actual-ideal self discrepancy(Self Questionnaire), and shame(Korean Version of Experience of Shame Scale; K-ESS), and the data were analyzed by structural equation. The results of the study are as follows. First, the effect of narcissistic vulnerability on self-silencing was partially mediated by self-discrepancy. Second, the effect of narcissistic vulnerability on self-silencing was also partially mediated by shame. Third, the effect of narcissistic vulnerability on self-silencing was progressively mediated by self discrepancy and shame. These findings suggest that narcissistic vulnerability tends to actively conceal more negative or imperfect self-aspect and tends to present perfect or more ideal self-aspect in order to protect the unstable self-esteem and actual-ideal self discrepancy and to defend against vulnerability for shame. The implications, limitations and suggestions for future researches were discussed.

Medicinal Herbs Inhibit Proinflammatory Mediators through the Suppression of JNK and p38 Activation in LPS-Stimulated Raw 264.7 Macrophages

Yura Choi,Seung Tack Oh,Seongmi Lee,Quan Feng Liu,Ha Jin Jung,Songhee Jeon 한국식품영양과학회 2015 한국식품영양과학회 학술대회발표집 Vol.2015 No.8

Analysis of Chain Branch of Polyolefins by a New Proton NMR Approach

Jung, Minhwan,Lee, Yura,Kwak, Sooyoung,Park, Heeyong,Kim, Byoungsoo,Kim, Sulhee,Lee, Kwang Hwan,Cho, Hye Sung,Hwang, Kwang Yeon American Chemical Society 2016 ANALYTICAL CHEMISTRY - Vol.88 No.3

<P>The crystallinity of polyethylene, which significantly affects the properties of the polymer, is quite sensitive to the concentration of its branches. Thus, it is necessary to estimate branch concentration with reasonable accuracy. Currently, C-13 NMR and gel permeation chromatography Fourier transform infrared spectroscopy are widely-used analysis methods for the analysis of branch concentration. Despite several advantages, these methods sometimes have limitations. For instance, the preparation of samples for C-13-NMR is tedious because high-concentration samples are required and the time for analysis is greater than 12 h. To more efficiently estimate the branch concentration of polyethylene, we developed a new high field H-1 NMR method with an improved peak resolution by employing (1) homonuclear decoupling and (2) 2D heteronuclear correlation. The new method was observed to significantly reduce the experimental time to similar to 30 min; furthermore, sample preparation was relatively simple because the method did not require high-concentration samples.</P>

Deep Learning Algorithm for Automated Segmentation and Volume Measurement of the Liver and Spleen Using Portal Venous Phase Computed Tomography Images

Ahn Yura,Yoon Jee Seok,Lee Seung Soo,Suk Heung-Il,Son Jung Hee,Sung Yu Sub,Lee Yedaun,Kang Bo-Kyeong,Kim Ho Sung 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.8

Objective: Measurement of the liver and spleen volumes has clinical implications. Although computed tomography (CT) volumetry is considered to be the most reliable noninvasive method for liver and spleen volume measurement, it has limited application in clinical practice due to its time-consuming segmentation process. We aimed to develop and validate a deep learning algorithm (DLA) for fully automated liver and spleen segmentation using portal venous phase CT images in various liver conditions. Materials and Methods: A DLA for liver and spleen segmentation was trained using a development dataset of portal venous CT images from 813 patients. Performance of the DLA was evaluated in two separate test datasets: dataset-1 which included 150 CT examinations in patients with various liver conditions (i.e., healthy liver, fatty liver, chronic liver disease, cirrhosis, and post-hepatectomy) and dataset-2 which included 50 pairs of CT examinations performed at ours and other institutions. The performance of the DLA was evaluated using the dice similarity score (DSS) for segmentation and Bland-Altman 95% limits of agreement (LOA) for measurement of the volumetric indices, which was compared with that of ground truth manual segmentation. Results: In test dataset-1, the DLA achieved a mean DSS of 0.973 and 0.974 for liver and spleen segmentation, respectively, with no significant difference in DSS across different liver conditions (p = 0.60 and 0.26 for the liver and spleen, respectively). For the measurement of volumetric indices, the Bland-Altman 95% LOA was -0.17 ± 3.07% for liver volume and -0.56 ± 3.78% for spleen volume. In test dataset-2, DLA performance using CT images obtained at outside institutions and our institution was comparable for liver (DSS, 0.982 vs. 0.983; p = 0.28) and spleen (DSS, 0.969 vs. 0.968; p = 0.41) segmentation. Conclusion: The DLA enabled highly accurate segmentation and volume measurement of the liver and spleen using portal venous phase CT images of patients with various liver conditions.

Safety and Usability Guidelines of Clinical Information Systems Integrating Clinical Workflow: A Systematic Review

Lee, Yura,Jung, Min-Young,Shin, Gee Won,Bahn, Sangwoo,Park, Taezoon,Cho, Insook,Lee, Jae-Ho Korean Society of Medical Informatics 2018 Healthcare Informatics Research Vol.24 No.3

<P><B>Objectives</B></P><P>The usability of clinical information systems (CISs) is known to be an essential consideration in ensuring patient safety as well as integrating clinical flow. This study aimed to determine how usability and safety guidelines of CIS consider clinical workflow through a systematic review in terms of the target systems, methodology, and guideline components of relevant articles.</P><P><B>Methods</B></P><P>A literature search was conducted for articles published from 2000 to 2015 in PubMed, Cochrane, EMBASE, Web of Science, and CINAHL. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement method was employed. Articles containing recommendations, principles, and evaluation items for CIS usability and safety were included. The selected articles were classified according to article type, methodology, and target systems. Taking clinical workflow into consideration, the components of guidelines were extracted and classified.</P><P><B>Results</B></P><P>A total of 7,401 articles were identified by keyword search. From the 76 articles remaining after abstract screening, 15 were selected through full-text review. Literature review (n = 7) was the most common methodology, followed by expert opinions (n = 6). Computerized physician order entry (n = 6) was the most frequent system. Four articles considered the entire process of clinical tasks, and two articles considered the principles of the entire process of user interface affecting clinical workflow. Only two articles performed heuristic evaluations of CISs.</P><P><B>Conclusions</B></P><P>The usability and safety guidelines of CISs need improvement in guideline development methodology and with consideration of clinical workflow.</P>

리소그래피 공정을 통한 발수, 친수 패턴을 갖는 알루미늄 표면 제작

김유라(Yura Kim),Sumit Barthwal,정미(Mi Jung),임시형(Si-Hyung Lim) 대한기계학회 2014 대한기계학회 춘추학술대회 Vol.2014 No.11