Prediction of canine ovulation using serum estradiol concentration

Zhao Minghui,Lee Seunghoon,No Jingu,Nam Yoonseok,Jeong Hae-yun,Ock Sun A,Yun JeongHee,Kim Dong-Hoon,Tai-Young 한국수정란이식학회 2017 한국수정란이식학회 학술대회 Vol.2017 No.05

Canine cloning have been succeeded for a decade. To obtain in vivo matured dog oocytes, Serum progesterone (P4) level were employed for ovulate determination. However, accuracy of P4 methods is not satisfied. The aim of this study was to compare both methods of serum estradiol (E2) and P4 on the accuracy of canine ovulation determination. Canine serum P4 and E2 concentration during both proestrus and estrus were detected. Correlation between accuracy of each method and environment temperature were analyzed. Following ovulation, oocytes were collected by surgery. As a result, higher percentage of mature oocytes was obtained when using E2 (56.43%) as compared to P4 (39.60%). Accuracy of P4 increased from spring (30.76%) to summer (47.92%) and decreased in autumn (37.50%) and winter (29.16%) gradually. Especially, E2 maintained about 50% to 65% whatever the season and temperature. Correlation analyze showed that dynamic of P4 accuracy highly correlated with environment temperate (Rp4=0.862) but E2 could not be affected by the temperature (RE2=0.199). To determine whether obtained oocytes by E2 method could be used for canine cloning, twenty canines were selected as oocyte donors, and two puppies were produced after somatic cell nuclear transfer(SCNT) and embryo transfer(ET) with the oocytes by E2 method. In conclusion, comparing to the P4 method, the E2 is an accuracy and reliable method for canine cloning.

A Weibo Topic Tracking System based on K-means

Yun Liu,Kun-Peng Xia,Jian-Xun Zhao 보안공학연구지원센터 2014 International Journal of Database Theory and Appli Vol.7 No.6

This article studied weibo text representation. For the weibo features such as short, real-time, colloquialism and originality, in the original vector space model, we propose a suitable method for weibo text representation. Make all the content words as feature words after participation. And we proposed T-TFIDF weight calculation method according to the features of weibo. According to the vector space model, we proposed a weibo adaptive topic tracking methods based on K-means clustering. Simulation analysis shows that, the method can by comparing the similarity micro-blog and sub topic vector set, determine whether weibo belonging to the topic.

Chinese herbal injections in combination with radiotherapy for advanced pancreatic cancer: A systematic review and network meta-analysis

Yun-Ru Chen,Ruo-Tong Zhao,Yi-Fang Xu,Yin-Jie Ma,Shao-Bo Hu,Xue-Hui Wang,Bing-Bing Fan,Yan-Ji Zhou,Yu-Bei Huang,Nicola Robinson,Jian-ping Liu,Zhao-Lan Liu 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.4

Background: Advanced pancreatic cancer (APC) is a fatal disease with limited treatment options. This study aims to evaluate the effectiveness and safety of different Chinese herbal injections (CHIs) as adjuvants for radiotherapy (RT) in APC and compare their treatment potentials using network meta-analysis. Methods: We systematically searched three English and four Chinese databases for randomized controlled trials (RCTs) from inception to July 25, 2023. The primary outcome was the objective response rate (ORR). Secondary outcomes included Karnofsky performance status (KPS) score, overall survival (OS), and adverse events (AEs). The treatment potentials of different CHIs were ranked using the surface under the cumulative ranking curve (SUCRA). The Cochrane RoB 2 tool and CINeMA were used for quality assessment and evidence grading. Results: Eighteen RCTs involving 1199 patients were included. Five CHIs were evaluated. Compound Kushen injection (CKI) combined with RT significantly improved ORR compared to RT alone (RR 1.49, 95 % CrI 1.21–1.86). Kanglaite (KLT) plus RT (RR 1.58, 95 % CrI 1.20–2.16) and CKI plus RT (RR 1.49, 95 % CrI 1.16–1.95) were associated with improved KPS score compared to radiation monotherapy, with KLT+RT being the highest rank (SUCRA 72.28 %). Regarding AEs, CKI plus RT was the most favorable in reducing the incidence of leukopenia (SUCRA 90.37 %) and nausea/vomiting (SUCRA 85.79 %). Conclusions: CKI may be the optimal choice of CHIs to combine with RT for APC as it may improve clinical response, quality of life, and reduce AEs. High-quality trials are necessary to establish a robust body of evidence. Protocol registration: PROSPERO, CRD42023396828.

Causes, Features, and Outcomes of Drug-Induced Liver Injury in 69 Children from China

( Yun Zhu ),( Yong Gang Li ),( Jia Bo Wang ),( Shu Hong Liu ),( Li Fu Wang ),( Yan Ling Zhao ),( Yun Feng Bai ),( Zhong Xia Wang ),( Jian Yu Li ),( Xiao He Xiao ) 대한소화기학회 2015 Gut and Liver Vol.9 No.4

Background/Aims: Drug-induced liver injury (DILI) is a frequent cause of pediatric liver disease; however, the data on DILI are remarkably limited. Methods: All 69 children hospitalized with DILI between January 2009 and December 2011 were retrospectively studied. Results: A total of 37.7% of the children had medical histories of respiratory infection. The clinical injury patterns were as follows: hepatocellular 89.9%, cholestatic 2.9%, and mixed 7.2%. Liver biopsies from 55 children most frequently demonstrated chronic (47.3%) and acute (27.3%) hepatitis. Hypersensitivity features, namely, fever (31.9%), rash (21.7%), and eosinophilia (1.4%), were found. Twenty-four children (34.8%) developed chronic DILI. Antibiotics (26.1%) were the most common Western medicines (WMs) causing DILI, and the major implicated herbs were Ephedra sinica and Polygonum multiflorum. Compared with WM, the children whose injuries were caused by Chinese herbal medicine (CHM) showed a higher level of total bilirubin (1.4 mg/dL vs 16.6 mg/dL, p=0.004) and a longer prothrombin time (11.8 seconds vs 17.3 seconds, p=0.012), but they exhibited less chronic DILI (2/15 vs 18/39, p=0.031). Conclusions: Most cases of DILI in children are caused by antibiotics or CHM used to treat respiratory infection and present with hepatocellular injury. Compared with WM, CHM is more likely to cause severe liver injury, but liver injury caused by CHM is curable. (Gut Liver 2015;9:525-533)

A Multi-center Survey of HPV Knowledge and Attitudes Toward HPV Vaccination among Women, Government Officials, and Medical Personnel in China

Zhao, Fang-Hui,Tiggelaar, Sarah M.,Hu, Shang-Ying,Zhao, Na,Hong, Ying,Niyazi, Mayinuer,Gao, Xiao-Hong,Ju, Li-Rong,Zhang, Li-Qin,Feng, Xiang-Xian,Duan, Xian-Zhi,Song, Xiu-Ling,Wang, Jing,Yang, Yun,Li, Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

Objectives: To assess knowledge of HPV and attitudes towards HPV vaccination among the general female population, government officials, and healthcare providers in China to assist the development of an effective national HPV vaccination program. Methods: A cross-sectional epidemiologic survey was conducted across 21 urban and rural sites in China using a short questionnaire. 763 government officials, 760 healthcare providers, and 11,681 women aged 15-59 years were included in the final analysis. Data were analyzed using standard descriptive statistics and logistic regression. Results: Knowledge of HPV among the general female population was low; only 24% had heard of HPV. Less than 20% of healthcare providers recognized sexually na$\ddot{i}$ve women as the most appropriate population for HPV vaccination. There was high acceptance of the HPV vaccine for all categories of respondents. Only 6% of women were willing to pay more than US $300 for the vaccine. Conclusions: Aggressive education is necessary to increase knowledge of HPV and its vaccine. Further proof of vaccine safety and efficacy and government subsidies combined with increased awareness could facilitate development and implementation of HPV vaccination in China.

Legal Issues of China's Possible Participation in the International Space Station: Comparing to the Russian Experience

Yun Zhao (사) 이준국제법연구원 2013 Journal of East Asia and International Law Vol.6 No.1

China has made great achievements in space activities in recent years. While emphasizing the principle of self-independence, China also acknowledges the importance of space cooperation. As early as 2001, China indicated its interest in joining the International Space Station. However, no substantive progress has been made concerning China's participation thus far. This may be a result of political and economic, rather than legal and technical, considerations. There is no doubt that China's participation shall contribute to the sustainable development of the ISS. China's participation could also offer an excellent opportunity to reexamine the 1998 framework and clarify or improve certain provisions that exist in the current regime. While technologically ready for participation, China should start considering possible legal issues that may arise from its participation in the ISS project. This article takes up the challenging task of identifying potential legal issues that may arise in the course of China's participation in the ISS and offers suggestions for a future cooperative legal framework regarding the ISS.

Disaster Management and the Tampere Convention

Yun Zhao 이준국제법연구원 2008 Journal of East Asia and International Law Vol.1 No.1

Compensation and Stochastic Modeling of Discrete-Time Networked Control Systems with Data Packet Disorder

Yun-Bo Zhao,Jongrae Kim,Guo-Ping Liu,David Rees 제어·로봇·시스템학회 2012 International Journal of Control, Automation, and Vol.10 No.5

Data packet disorder is inevitable in discrete-time networked control systems, which however has been ignored in most literature to date. This work investigates the cause and the negative effects of data packet disorder in discrete-time networked control systems, and a compensation scheme is proposed to deal with these negative effects. This analysis shows that most existing works in the related areas have assumed unrealistic characteristics of the communication network and thus further improvements within this new framework are necessary. For this purpose the closed-loop system with the use of the proposed compensation scheme is mathematically modeled as a Markov jump systems, and stochastic stability and stabilization results are then obtained. Numerical examples illustrate the negative effects caused by data packet disorder and also the effectiveness of the proposed approach.

Explore China cold regions village residential green technology strategy

ZHAO Yun duo,Wang zi wen 국제온돌학회 2013 International Journal of Ondol Vol.2013 No.-

In 2013, the Chinese government formulated the Action Plan for Green Building , which focuses on the task clearly should actively promote the construction of rural housing. In this paper, for the question about how to promote the cold region of China rural house green, put forward to improve the quality of residential priority, to save energy resources as the most important,and to use pervasive technology-based applications as the main content,which is basic principles.The paper also proposed four technical strategies for a new house on the village is to use local natural resources, to optimize the design to improve the quality of living,to reduce shape coefficient to adjust the layout,to improve the insulation properties of architecture maintenance in structure increases.And with the above principles and technology strategies,I design a green rural house which reflect on the characteristics of cold region.

Prediction of tensile strength degradation of corroded steel based on in-situ pitting evolution

Yun Zhao,Qi Guo,Zizhong Zhao,Xian Wu,Ying Xing 국제구조공학회 2023 Steel and Composite Structures, An International J Vol.46 No.3

Steel is becoming increasingly popular due to its high strength, excellent ductility, great assembly performance, and recyclability. In reality, steel structures serving for a long time in atmospheric, industrial, and marine environments inevitably suffer from corrosion, which significantly decreases the durability and the service life with the exposure time. For the mechanical properties of corroded steel, experimental studies are mainly conducted. The existing numerical analyses only evaluate the mechanical properties based on corroded morphology at the isolated time-in-point, ignoring that this morphology varies continuously with corrosion time. To solve this problem, the relationships between pit depth expectation, standard deviation, and corrosion time are initially constructed based on a large amount of wet-dry cyclic accelerated test data. Successively, based on that, an in-situ pitting evolution method for evaluating the residual tensile strength of corroded steel is proposed. To verify the method, 20 repeated simulations of mass loss rates and mechanical properties are adopted against the test results. Then, numerical analyses are conducted on 135 models of corrosion pits with different aspect ratios and uneven corrosion degree on two corroded surfaces. Results show that the power function with exponents of 1.483 and 1.091 can well describe the increase in pit depth expectation and standard deviation with corrosion time, respectively. The effect of the commonly used pit aspect ratios of 0.10–0.25 on yield strength and ultimate strength is negligible. Besides, pit number ratio α equating to 0.6 is the critical value for the strength degradation. When α is less than 0.6, the pit number increases with α, accelerating the degradation of strength. Otherwise, the strength degradation is weakened. In addition, a power function model is adopted to characterize the degradation of yield strength and ultimate strength with corrosion time, which is revised by initial steel plate thickness.