An Optimization Method for Designing LDPC Analog Decoders Based on Frequent Subgraph Mining Algorithm

Yuan Gao,Yujie Lin,Jibo Dai 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.10

To lower the mapping complexity of designing analog decoders, a method to optimize the design of low-density parity-check (LDPC) analog decoders is proposed in this paper. Based on factor graphs and the sum-product algorithm, the LDPC decoding process on the factor graph and the construction of analog decoders are exploited. Then the frequent subgraph mining algorithm is introduced to search the isomorphic subgraphs in factor graphs. According to the output of the frequent subgraph mining algorithm which enumerates all the subgraphs in factor graphs, the mapping complexity of a LDPC analog decoder can be significantly reduced. Finally, a (40, 16) LDPC analog decoder is constructed using the proposed method. Simulation results show that the need to place gates and connections can be reduced 90% and 23%, respectively, and the ideal performance is obtained by carefully choosing unit currents and decoding time.

Characterization of Extracellular Polysaccharides from Nostoc flagelliforme Cells in Liquid Suspension Culture

Jia, Shiru,Yu, Haifeng,Lin, Yongxian,Dai, Yujie Korean Society for Biotechnology and Bioengineerin 2007 Biotechnology and Bioprocess Engineering Vol.12 No.3

Nostoc flagelliforme cells were studied with regard to the physico-chemical characterization of the extracellular polysaccharides (EPS) secreted in a liquid suspension culture. The hydrolyzed EPS were determined to be composed of four neutral sugars, which were glucose (43.2%), xylose (20.6%), galactose (29.9%), and mannose (6.3%). The glucuronic acid was the only uronic acid identified in the residue. The apparent molecular weight was estimated at $2.79{\times}10^5$. The Fourier transform infrared spectra showed that the EPS evidenced characteristics typical of non-sulfated polysaccharides. The UV spectrum and Bradford reaction indicated that there were no nucleic acids and proteins in them. The thermal analysis showed a decomposition peak at $245^{\circ}C$ on the thermogravimetric (TG) curves. The scanning electron microscope (SEM) analysis indicated that the EPS possessed a porous structure. The observed microstructural irregularities indicated that the polysaccharide was a type of amorphous solid. These results showed that the EPS of N. flagelliforme cells might be employed as a substitute for those normally derived from field colonies. The results of this study may prove to be beneficial to the protection of the natural resource represented by N. flagelliforme.

Characterization of Extracellular Polysaccharides from Nostoc flagelliforme Cells in Liquid Suspension Culture

Shiru Jia,Haifeng Yu,Yongxian Lin,Yujie Dai 한국생물공학회 2007 Biotechnology and Bioprocess Engineering Vol.12 No.3

Nostoc flagelliforme cells were studied with regard to the physico-chemical characterization of the extracellular polysaccharides (EPS) secreted in a liquid suspension culture. The hydrolyzed EPS were determined to be composed of four neutral sugars, which were glucose (43.2%), xylose (20.6%), galactose (29.9%), and mannose (6.3%). The glucuronic acid was the only uronic acid identified in the residue. The apparent molecular weight was estimated at 2.79 × 105. The Fourier transform infrared spectra showed that the EPS evidenced characteristics typical of non-sulfated polysaccharides. The UV spectrum and Bradford reaction indicated that there were no nucleic acids and proteins in them. The thermal analysis showed a decomposition peak at 245oC on the thermogravimetric (TG) curves. The scanning electron microscope (SEM) analysis indicated that the EPS possessed a porous structure. The observed microstructural irregularities indicated that the polysaccharide was a type of amorphous solid. These results showed that the EPS of N. flagelliforme cells might be employed as a substitute for those normally derived from field colonies. The results of this study may prove to be beneficial to the protection of the natural resource represented by N. flagelliforme.

LA-ICP-MS zircon U-Pb age and Hf isotope data from the granitic rocks in the Iwakuni area, southwest Japan: reevaluation of emplacement order and the source magma

Tayyaba Mateen,Kazuaki Okamoto,Sun-Lin Chung,Kuo-Lung Wang,Hao-Yang Lee,Shuhei Abe,Yuji Mita,Hafiz U. Rehman,Masaru Terabayashi,Hiroshi Yamamoto 한국지질과학협의회 2019 Geosciences Journal Vol.23 No.6

U-Pb-Hf isotopes of zircons from the granitic intrusive rocks in the Iwakuni area of southwest Japan are determined by LA-ICP-MS analysis. The Gamano Granodiorite belonging to the Older Ryoke Granites of the Ryoke Belt yielded U-Pb mean age of 92.3 ± 2.6 Ma (MSWD = 1.8). The Namera Granite belonging to the Younger Ryoke Granites of the Ryoke Belt yielded U-Pb mean age of 106.3 ± 1.6 Ma (MSWD = 2.3). The Shimokuhara Granite belonging to the Hiroshima Granites of the San-yo Belt yielded U-Pb mean age of 103.8 ± 1.5 Ma (MSWD = 0.32). A granite porphyry sample taken from about 15 m thick dike discordantly intruded into pelitic schist of the Ryoke metamorphic rocks yielded U-Pb mean age of 92.5 ± 1.6 Ma (MSWD = 0.63). Hf isotope data, obtained from the same dated zircon grains, show initial 176Hf/177Hf isotopic ratios referred to as “εHf(t)” generally ranging between –4.8 and +1.1 except an anomalously low value (–15.0) from an inherited core. The εHf(t) values, calculated with average crustal 176Lu/177Hf ratio of 0.015, correspond to Hf isotope crustal model ages between 1474 to 1087 Ma (Mesoproterozoic). The Gamano Graodiorite has long been regarded to be a syn-tectonic intrusion, but the zircon ages and εHf(t) values are similar to those of the post-tectonic granite porphyry dike. The results of this study together with available U-Pb zircon ages of granitic rocks in the Iwakuni area reported elsewhere reveal that the order of emplacement indicated by the U-Pb zircon ages are much discrepant with the traditional classification, the Older Ryoke, the Younger Ryoke. It is better to refrain from the use of “Older” and “Younger” for the collective names of the granitic intrusive bodies.

Aging effects on chemical transformation and metal(loid) removal by entrapped nanoscale zero-valent iron for hydraulic fracturing wastewater treatment

Sun, Yuqing,Lei, Cheng,Khan, Eakalak,Chen, Season S.,Tsang, Daniel C.W.,Ok, Yong Sik,Lin, Daohui,Feng, Yujie,Li, Xiang-dong Elsevier 2018 Science of the Total Environment Vol.615 No.-

<P><B>Abstract</B></P> <P>In this study, alginate and polyvinyl alcohol (PVA)-alginate entrapped nanoscale zero-valent iron (nZVI) was tested for structural evolution, chemical transformation, and metals/metalloids removal (Cu(II), Cr(VI), Zn(II), and As(V)) after 1–2month passivation in model saline wastewaters from hydraulic fracturing. X-ray diffraction analysis confirmed successful prevention of Fe<SUP>0</SUP> corrosion by polymeric entrapment. Increasing ionic strength (<I>I</I>) from 0 to 4.10M (deionized water to Day-90 fracturing wastewater (FWW)) with prolonged aging time induced chemical instability of alginate due to dissociation of carboxyl groups and competition for hydrogen bonding with nZVI, which caused high Na (7.17%) and total organic carbon (24.6%) dissolution from PVA-alginate entrapped nZVI after 2-month immersion in Day-90 FWW. Compared to freshly-made beads, 2-month aging of PVA-alginate entrapped nZVI in Day-90 FWW promoted Cu(II) and Cr(VI) uptake in terms of the highest removal efficiency (84.2% and 70.8%), pseudo-second-order surface area-normalized rate coefficient <I>k</I> <SUB> <I>sa</I> </SUB> (2.09×10<SUP>−1</SUP> Lm<SUP>−2</SUP> h<SUP>−1</SUP> and 1.84×10<SUP>−1</SUP> Lm<SUP>−2</SUP> h<SUP>−1</SUP>), and Fe dissolution after 8-h reaction (13.9% and 8.45%). However, the same conditions inhibited Zn(II) and As(V) sequestration in terms of the lowest removal efficiency (31.2% and 39.8%) by PVA-alginate nZVI and <I>k</I> <SUB> <I>sa</I> </SUB> (4.74×10<SUP>−2</SUP> Lm<SUP>−2</SUP> h<SUP>−1</SUP> and 6.15×10<SUP>−2</SUP> Lm<SUP>−2</SUP> h<SUP>−1</SUP>) by alginate nZVI. The X-ray spectroscopic analysis and chemical speciation modelling demonstrated that the difference in metals/metalloids removal by entrapped nZVI after aging was attributed to distinctive removal mechanisms: (i) enhanced Cu(II) and Cr(VI) removal by nZVI reduction with accelerated electron transfer after pronounced dissolution of non-conductive polymeric immobilization matrix; (ii) suppressed Zn(II) and As(V) removal by nZVI adsorption due to restrained mass transfer after blockage of surface-active micropores. Entrapped nZVI was chemically fragile and should be properly stored and regularly replaced for good performance.</P> <P><B>Highlights</B></P> <P> <UL> <LI> nZVI entrapment successfully prevented Fe<SUP>0</SUP> corrosion in fracturing wastewaters. </LI> <LI> Entrapped nZVI was chemically fragile due to dissolution of Na and TOC. </LI> <LI> nZVI passivation promoted Cu(II) and Cr(VI) but inhibited Zn(II) and As(V) removal. </LI> <LI> Effects of nZVI aging on removal efficiency depended on interaction mechanisms. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Nanoscale zero-valent iron for metal/metalloid removal from model hydraulic fracturing wastewater

Sun, Yuqing,Lei, Cheng,Khan, Eakalak,Chen, Season S.,Tsang, Daniel C.W.,Ok, Yong Sik,Lin, Daohui,Feng, Yujie,Li, Xiang-dong Elsevier 2017 CHEMOSPHERE - Vol.176 No.-

<P><B>Abstract</B></P> <P>Nanoscale zero-valent iron (nZVI) was tested for the removal of Cu(II), Zn(II), Cr(VI), and As(V) in model saline wastewaters from hydraulic fracturing. Increasing ionic strength (<I>I</I>) from 0.35 to 4.10 M (Day-1 to Day-90 wastewaters) increased Cu(II) removal (25.4–80.0%), inhibited Zn(II) removal (58.7–42.9%), slightly increased and then reduced Cr(VI) removal (65.7–44.1%), and almost unaffected As(V) removal (66.7–75.1%) by 8-h reaction with nZVI at 1–2 g L<SUP>−1</SUP>. The removal kinetics conformed to pseudo-second-order model, and increasing <I>I</I> decreased the surface area-normalized rate coefficient (<I>k</I> <SUB> <I>sa</I> </SUB>) of Cu(II) and Cr(VI), probably because agglomeration of nZVI in saline wastewaters restricted diffusion of metal(loid)s to active surface sites. Increasing <I>I</I> induced severe Fe dissolution from 0.37 to 0.77% in DIW to 4.87–13.0% in Day-90 wastewater; and Fe dissolution showed a significant positive correlation with Cu(II) removal. With surface stabilization by alginate and polyvinyl alcohol, the performance of entrapped nZVI in Day-90 wastewater was improved for Zn(II) and Cr(VI), and Fe dissolution was restrained (3.20–7.36%). The X-ray spectroscopic analysis and chemical speciation modelling demonstrated that the difference in removal trends from Day-1 to Day-90 wastewaters was attributed to: (i) distinctive removal mechanisms of Cu(II) and Cr(VI) (adsorption, (co-)precipitation, and reduction), compared to Zn(II) (adsorption) and As(V) (bidentate inner-sphere complexation); and (ii) changes in solution speciation (e.g., from Zn<SUP>2+</SUP> to ZnCl<SUB>3</SUB> <SUP>−</SUP> and ZnCl<SUB>4</SUB> <SUP>2−</SUP>; from CrO<SUB>4</SUB> <SUP>2−</SUP> to CaCrO<SUB>4</SUB> complex). Bare nZVI was susceptible to variations in wastewater chemistry while entrapped nZVI was more stable and environmentally benign, which could be used to remove metals/metalloids before subsequent treatment for reuse/disposal.</P> <P><B>Highlights</B></P> <P> <UL> <LI> nZVI could remove Cu(II), Zn(II), Cr(VI), and As(V) from fracturing wastewaters. </LI> <LI> High salinity enhanced Fe dissolution and reduced removal rates except Cu(II). </LI> <LI> nZVI entrapment mitigated Fe dissolution and improved metal(loid) removal. </LI> <LI> Removal efficiency varied with interaction mechanisms and solution speciation. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

북한 증산-평원지역 화강편마암의 LA-ICP-MS U-Pb 저콘 연대

송용선(Yong-Sun Song),박계헌(Kye-Hun Park),이호선(Ho-Sun Lee),Cao Lin,Orihashi Yuji 한국암석학회 2009 암석학회지 Vol.18 No.2

북한의 평안분지 서부의 증산-평원지역에 분포하는 선캠브리아 기저를 이루는 화강편마암에서 분리한 저콘에 대하여 LA-ICP-MS U-Pb 연대측정을 실시하였다. 그 결과 1,873±19(2σ) Ma의 일치곡선연령을 구하였으며 이는 고원생대의 화강암질 화성활동을 나타낸다. 한반도의 선캠브리아 기저지각 암석들로부터 SHRIMP 및 LA-ICP-MS 등의 방법에 의해 구한 최근의 정밀한 연대자료를 살펴보면 영남육괴, 경기육괴, 낭림육괴 등 한반도 전역에서 이 화강편마암과 마찬가지로 ~1870 Ma의 연령이 가장 빈도 높게 보고되고 있다. 이 시기의 지질사건들은 지역에 따라 화강암질 화성활동뿐만 아니라 고온의 광역변성작용도 함께 나타나는 것으로 해석되고 있다. 인접한 중국의 북중국과 남중국지괴들 역시 유사한 시기의 화성 및 변성활동들이 보고되고 있으며 한반도의 선캠브리아 육괴들이 북중국과 남중국 어느 지괴와 대비되는지는 더 많은 자료와 연구가 필요하다. LA-ICP-MS U-Pb zircon age was determined from the granite gneiss from Jeungsan-Pyeongwon area located to the west of Pyeongan Basin, North Korea, yielding concordant age of 1,873±19(2σ) Ma interpreted as Paleoproterozoic granitic magmatism. Considering relatively precise data reported recently using SHRIMP and LA-ICP-MS, ages around 1,870 Ma have been most frequently reported from Precambrian basement rocks of Korean peninsula, including Yeongnam, Gyeonggi, and Nangnim massifs altogether. Geologic events of this period are interpreted as not only granitic magmatism but also hightemperature regional metamorphism depending on their localities. The magmatic and regional metamorphic events of similar periods have also been reported from neighboring cratons of both North China and South China. Therefore, we need more data and efforts to decipher correlation between Precambrian basements between Korea and China.

Clinical Evidence of Chemotherapy or Endocrine Therapy Maintenance in Patients with Metastatic Breast Cancer: Meta-analysis from Randomized Clinical Trials and Propensity Score Matching of Multicentre Cohort Study

Wei Ren,Yunfang Yu,Huangming Hong,Ying Wang,Quanlong Gao,Yongjian Chen,Peixian Chen,Jianli Zhao,Qiyun Ou,Dagui Lin,Tuping Fu,Yujie Tan,Chenchen Li,Xinxin Xie,Guolin Ye,Jun Tang,Herui Yao 대한암학회 2022 Cancer Research and Treatment Vol.54 No.4

Purpose This study aims to comprehensively evaluate the clinical efficacy of chemotherapy or endocrine therapy maintenance in metastatic breast cancer (MBC) patients. Materials and Methods The meta-analysis of randomized clinical trials (RCTs) and propensity score matching of multicenter cohort study evaluated MBC patients who underwent first-line chemotherapy or endocrine therapy maintenance. This study is registered with PROSPERO: CRD42017071858 and ClinicalTrials.gov: NCT04258163. Results A total of 2,867 patients from 15 RCTs and 760 patients from multicenter cohort were included. The results from meta-analysis showed that chemotherapy maintenance improved progression-free survival (PFS) (hazard ratio [HR], 0.63; 95% confidence interval [CI], 0.54 to 0.73; p < 0.001; moderate-quality evidence) and overall survival (OS) (HR, 0.87; 95% CI, 0.78 to 0.97; p=0.016; high-quality evidence) than observation. In the cohort study, for hormone receptor–positive MBC patients, chemotherapy maintenance improved PFS (HR, 0.67; 95% CI, 0.52 to 0.85; p < 0.001) and OS (HR, 0.55; 95% CI, 0.42 to 0.73; p < 0.001) compared with observation, and endocrine therapy maintenance also improved PFS (HR, 0.65; 95% CI, 0.53 to 0.80; p < 0.001) and OS (HR, 0.55; 95% CI, 0.44 to 0.69; p < 0.001). There were no differences between chemotherapy and endocrine therapy maintenance in PFS and OS (all p > 0.05). Regardless of the continuum or switch maintenance therapy, showed prolonged survival in MBC patients who were response to first-line treatment. Conclusion This study provided evidences for survival benefits of chemotherapy and endocrine therapy maintenance in MBC patients, and there was no difference efficacy between chemotherapy and endocrine therapy maintenance for hormone receptor–positive patients.

Removal of chlorinated organic solvents from hydraulic fracturing wastewater by bare and entrapped nanoscale zero-valent iron

Lei, Cheng,Sun, Yuqing,Khan, Eakalak,Chen, Season S.,Tsang, Daniel C.W.,Graham, Nigel J.D.,Ok, Yong Sik,Yang, Xin,Lin, Daohui,Feng, Yujie,Li, Xiang-Dong Elsevier 2018 CHEMOSPHERE - Vol.196 No.-

<P><B>Abstract</B></P> <P>With the increasing application of hydraulic fracturing, it is urgent to develop an effective and economically feasible method to treat the large volumes of fracturing wastewater. In this study, bare and entrapped nanoscale zero-valent iron (nZVI) were introduced for the removal of carbon tetrachloride (CT) and 1,1,2-trichloroethane (TCA) in model high-salinity fracturing wastewater. With increasing ionic strength (<I>I</I>) from Day-1 (<I>I</I> = 0.35 M) to Day-90 (<I>I</I> = 4.10 M) wastewaters, bare nZVI presented significantly lower removal efficiency of CT (from 53.5% to 38.7%) and 1,1,2-TCA (from 71.1% to 21.7%) and underwent more serious Fe dissolution from 1.31 ± 1.19% in Day-1 to 5.79 ± 0.32% in Day-90 wastewater. Particle aggregation induced by high ionic strength was primarily responsible for the lowered performance of nZVI due to less available reactive sites on nZVI surface. The immobilization of nZVI in alginate with/without polyvinyl alcohol provided resistance to particle aggregation and contributed to the superior performance of entrapped nZVI in Day-90 wastewater for 1,1,2-TCA removal (62.6–72.3%), which also mitigated Fe dissolution (4.00–4.69%). Both adsorption (by polymer matrix) and reduction (by immobilized nZVI) were involved in the 1,1,2-TCA removal by entrapped nZVI. However, after 1-month immersion in synthetic fracturing wastewater, a marked drop in the reactivity of entrapped nZVI for 1,1,2-TCA removal from Day-90 wastewater was observed with significant release of Na and total organic carbon. In summary, bare nZVI was sensitive to the nature of the fracturing wastewater, while the use of environmentally benign entrapped nZVI was more promising for wastewater treatment.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Increasing ionic strength decreased nZVI reactivity and increased Fe dissolution. </LI> <LI> Entrapping nZVI in polymer matrix improved reactivity and limited Fe dissolution. </LI> <LI> Entrapped nZVI removed model chlorinated organic via both adsorption and reduction. </LI> <LI> Aging process was mitigated by polymer matrix but still inhibited nZVI reactivity. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>