Radiological gastrostomy: A comparative analysis of different image-guided methods

Hong-Tao Hu,Hang Yuan,Chen-Yang Guo,Quan-Jun Yao,Xiang Geng,Hong-Tao Cheng,Jun-Li Ma,Yan Zhao,Li Jiang,Yu-Qing Zhao,Hai-Liang Li 소화기인터벤션의학회 2021 Gastrointestinal Intervention Vol.10 No.2

Background: Radiographic guided percutaneous gastrostomy has become a safe and effective enteral nutrition method for patients who can not eat by mouth. Fluoroscopy, computed tomography (CT) and cone-beam CT have been routinely used clinically. The aim of this study was to compare the advantages and disadvantages of percutaneous gastrostomy using different radiographic guided methods. Methods: We retrospectively analyzed the clinical data of 538 patients undergoing percutaneous gastrostomy in our department. According to the image guidance method used in gastrostomy, the patients were divided into groups A by fluoroscopy guidance, group B by fluoroscopy combined with C-arm CT guidance, and group C with the whole process CT guidance. The gastrostomy success rate, complication rate, procedure time, and patient radiation dose were analyzed in the three groups. Results: Among 538 patients, 534 were successful and the success rates are 94.3%, 99.3%, and 100% in group A, B, and C, respectively (P > 0.05). There were 3 cases occurred postoperative bleeding as serious adverse events and transferred to surgical gastrostomy. The minor complications include local infection, hyperplasia of granulation tissue, tube obstruction or prolapse, and local pain of the ostomy. The minor complication rates were 10.5%, 10.4%, and 7.7% in group A, B, and C, respectively (P > 0.05). The average procedure time was 25.57 ± 5.99 minutes, 29.01 ± 6.63 minutes, and 45.47 ± 8.98 minutes, respectively (χ2 = 87.98, P < 0.001). The average radiation dosage was 27.30 ± 19.27 mGy, 145.07 ± 106.08 mGy, and 2,590.26 ± 1,088.22 mGy, respectively (χ2 = 204.44, P < 0.001). Conclusion: There were no significant differences in the success rates and complication rates of gastrostomy under the three guiding methods. For difficult cases, CT-guided gastrostomy may be a very useful supplemental method.

Radiological gastrostomy: A comparative analysis of different image-guided methods

Hong-Tao Hu,Hang Yuan,Chen-Yang Guo,Quan-Jun Yao,Xiang Geng,Hong-Tao Cheng,Jun-Li Ma,Yan Zhao,Li Jiang,Yu-Qing Zhao,Hai-Liang Li 소화기인터벤션의학회 2021 International journal of gastrointestinal interven Vol.10 No.2

Background: Radiographic guided percutaneous gastrostomy has become a safe and effective enteral nutrition method for patients who can not eat by mouth. Fluoroscopy, computed tomography (CT) and cone-beam CT have been routinely used clinically. The aim of this study was to compare the advantages and disadvantages of percutaneous gastrostomy using different radiographic guided methods. Methods: We retrospectively analyzed the clinical data of 538 patients undergoing percutaneous gastrostomy in our department. According to the image guidance method used in gastrostomy, the patients were divided into groups A by fluoroscopy guidance, group B by fluoroscopy combined with C-arm CT guidance, and group C with the whole process CT guidance. The gastrostomy success rate, complication rate, procedure time, and patient radiation dose were analyzed in the three groups. Results: Among 538 patients, 534 were successful and the success rates are 94.3%, 99.3%, and 100% in group A, B, and C, respectively (P > 0.05). There were 3 cases occurred postoperative bleeding as serious adverse events and transferred to surgical gastrostomy. The minor complications include local infection, hyperplasia of granulation tissue, tube obstruction or prolapse, and local pain of the ostomy. The minor complication rates were 10.5%, 10.4%, and 7.7% in group A, B, and C, respectively (P > 0.05). The average procedure time was 25.57 ± 5.99 minutes, 29.01 ± 6.63 minutes, and 45.47 ± 8.98 minutes, respectively (χ2 = 87.98, P < 0.001). The average radiation dosage was 27.30 ± 19.27 mGy, 145.07 ± 106.08 mGy, and 2,590.26 ± 1,088.22 mGy, respectively (χ2 = 204.44, P < 0.001). Conclusion: There were no significant differences in the success rates and complication rates of gastrostomy under the three guiding methods. For difficult cases, CT-guided gastrostomy may be a very useful supplemental method.

Apoptotic effects of 1,5-bis-(5-nitro-2-furanyl)-1,4-pentadien-3- one on Drosophila SL2 cells

Yuan-Hang Ren,Hong Jin,Ke Tao,Tai-Ping Hou 대한독성 유전단백체 학회 2015 Molecular & cellular toxicology Vol.11 No.2

n recent years, concerns over the potential impact of synthetic pesticides on the environment have promoted the research and development of environmentally friendly “green” pesticides. In the current study, we utilized a green biomimetic insecticide, 1,5-bis- (5-nitro-2-furanyl)-1,4-pentadien-3-one (compound C), to examine its cytotoxicity on an insect cell line, Drosophila melanogaster (SL2). Results from MTT assay showed cells treated with 100 μM of compound C for 48 h significantly inhibited the growth of SL2 cells by 87.71±0.96%. We subsequently attempted to illustrate the act on mechanism of compound C at the cellular level and found that it initiated apoptosis through a mitochondrial-dependent mechanism that increased the activity of caspase-3 and altered the cell cycle. These results suggest that the green biomimetic insecticide, compound C, is a novel and potent inducer of insect cell apoptosis.

Enhancing mucosal immunity in mice by recombinant adenovirus expressing major epitopes of porcine circovirus-2 capsid protein delivered with cytosine-phosphate-guanosine oligodeoxynucleotides

Hong-tao Chang,Xiu-yuan He,Yu-Feng Liu,Lu Chen,Quan-hai Guo,Qiu-ying Yu,Jun Zhao,Xin-wei Wang,Xia Yang,Chuan-qing Wang 대한수의학회 2014 Journal of Veterinary Science Vol.15 No.3

A recombinant replication-defective adenovirus expressingthe major epitopes of porcine circovirus-2 (PCV-2) capsidprotein (rAd/Cap/518) was previously constructed and shownto induce mucosal immunity in mice following intranasaldelivery. In the present study, immune responses induced byintranasal immunization with a combination of rAd/Cap/518and cytosine-phosphate-guanosine oligodeoxynucleotides(CpG ODN) were evaluated in mice. The levels ofPCV-2-specific IgG in serum and IgA in saliva, lung, andintestinal fluids were significantly higher in the groupimmunized with rAd/Cap/518 and CpG ODN than animalsimmunized with rAd/Cap/518 alone. The frequencies ofIL-2-secreting CD4+ T cells and IFN-γ-producing CD8+ T cellswere significantly higher in the combined immunizationgroup than mice immunized with rAd/Cap/518 alone. Thefrequencies of CD3+, CD3+CD4+CD8−, and CD3+CD4−CD8+T cells in the combined immunization group were similar tothat treated with CpG ODN alone, but significantly higherthan mice that did not receive CpG ODN. PCV-2 load afterchallenge in the combined immunization group wassignificantly lower than that in the phosphate-buffered salineplacebo group and approximately 7-fold lower in the grouptreated with CpG ODN alone. These results indicate thatrAd/Cap/518 combined with CpG ODN can enhance systemicand local mucosal immunity in mice, and represent apromising synergetic mucosal vaccine against PCV-2.

Crack Resistance and Strength Properties of Red Clay Modified with Lignocellulose and Guar gum

Hong-Yuan Fu,Guang-Tao Yu,Qian-Feng Gao,Ling Zeng,Shuo-Peng Cao 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.10

Desiccation cracking is a common problem of red clay under wet and dry conditions. The presence of cracks could reduce soil strength properties, which is the major reason for shallow failure of red clay slopes. This study aims to propose some additives to improve the crack resistance as well as the strength of red clay. To this end, three natural fibers and three natural gels were primarily selected to modify red clay. Desiccation crack tests were conducted to identify the best fiber and gel in terms of crack resistance. Then, direct shear tests and uniaxial tensile tests were performed on the soil specimens modified by the best fiber and gel to determine the optimal dosages regarding strength improvements. The results demonstrated that natural gels reduced the crack resistance of red clay, while natural fibers could enhance the crack resistance. Lignocellulose was the best additive in improving the crack resistance of red clay, and the modified effect was positively correlated with the fiber dosage. Adding 1.5% lignocellulose into red clay could reduce the crack rate from 2.19% to 0.30%, with a reduction of 0.86 times. The tensile strength, shear strength and its parameters of lignocellulose-modified red clay showed a trend of increasing first and then decreasing with increasing lignocellulose dosage. At the optimal lignocellulose dosage of 0.75%, the shear strength and tensile strength were increased by 44.63% and 18.21%, respectively. The strength of red clay modified by both lignocellulose and guar gum was positively correlated with the dosage of guar gum, and the desirable dosage of guar gum was 1.0%. In engineering practice, the wet red clay mixed with 0.75% lignocellulose and grass seeds can be employed as planting soil and is sprayed uniformly onto the slope surface after excavation using a spraying planting machine. To further improve the strength of the planting soil, 1.0% guar gum solution can be sprayed on the soil surface. The findings could provide useful guidance for the protection of red clay slopes.

Separation Technology, Thermodynamics : Study of adsorption behavior using activated carbon for removal of colored impurities from 30% caprolactam solution produced by means of SNIA-toluene-technology

( Hong Tao Zhang ),( Ping Yu ),( Zhen Yuan ),( Yun Bai Luo ) 한국화학공학회 2006 Korean Journal of Chemical Engineering Vol.23 No.3

Peniciside, a New Triterpenoid Glycoside, from the Fungus Penicillium sp. 169

Xiao-Hong Yuan,Guo-You Li,Guo-Bo Xu,Wei-Lin Wu,Tao Yang 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.2

Peniciside, a new fernene triterpenoid glycoside, was isolated from the EtOAc extract of the solid-state fermented rice culture of the fungus Penicillium sp. 169. Its structure was elucidated on the basis of spectroscopic analysis, and the absolute configuration was determined by X-ray crystallographic analysis and chemical methods. Peniciside is the first example of a fernene triterpenoid glycoside with two hydroxyls at C-19 and C-20.

Acetylcholinesterase Inhibitive Activity-Guided Isolation of Two New Alkaloids from Seeds of Peganum Nigellastrum Bunge by an In Vitro TLC- Bioautographic Assay

Xi-yuan Zheng,Chang-hong Wang,Zi-jia Zhang,Gui-xin Chou,Tao Wu,Xue-mei Cheng,Zheng-tao Wang 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.9

Acetylcholinesterase inhibitors (AChEIs) currently form the basis of the newest drugs available for the treatment of Alzheimer's disease. For the aim of screening effective AChEIs, the methanol extracts of the seeds of genus Peganum were found to show significant inhibitory activity of acetylcholinesterase enzyme (AChE) using an in vitro TLC-bioautographic assay. In further studies to seed of P. nigellastrum Bunge, activity-guided fractionation led to the isolation of two new alkaloids nigellastrine Ⅰ (9) and nigellastrine Ⅱ (10), and along with eight known alkaloids, vasicinone (1), vasicine (2), harmine (3), deoxyvasicinone (4), deoxyvasicine (5), harmaline (6), harmol (7), harman (8), in which harmol and harman were first isolated from species P. nigellastrum Bunge. As active constituents, all compounds showed good inhibitory activities against AChE. The results of in vitro semi-quality TLC-bioautographic assay showed that harmine, harmaline and harmol displayed a similar AChE inhibitive activities comparing to galanthamine. These results indicated that these alkaloids in P. nigellastrum Bunge could be a potent class of AChEIs.

Expanded Android Application for Openflow-based Visual Interface in Software-Defined Network

Xuejun Tao,Xueguang Yuan,Yan Hong,Yang’ An Zhang 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.6

In the past year, the northbound interface application has become a hot topic in the Software-Defined Network technology. It offers an opening method and makes people able to develop own business application upper the SDN. In this paper, we propose and evaluate a visual plane based on android phone application to present an explicit watch of the state and working performance of the Openflow-based underlying network topology in Software-Defined Network. The impacts of the designing architecture are evaluated in the form of software simulation and actual operating effects of the android application that we have designed. Through the interface opened by the floodlight controller to the upper business application, we are aimed at making it able to call the underlying network resources and inquiry its status information conveniently. So this paper wants to achieve the unified dispatching by elaborated methods and transplants the idea to the android application. By the way of the software programming, we could make the android phone to probe the southbound network resources through the northbound interface whose connotation we will expand. Between the northbound interface and the android application, we introduce a data center and select the mysql database to implement its function. Through the technology framework we built, we are able to use an android phone to access the status of the underlying devices and monitor the software defined network better aiming at providing better service. And we judge its function from the perspective of overall feasibility and stability not only through the system performance but also sound experiment effects. Finally, we can use any android phone to view about the topology of the network effectively and simply.

Isolation and Cloning of Porcine SLC27A2 Gene and Detection of Its Polymorphism Associated with Growth and Carcass Traits

Wang, Tao,Liu, Chang,Xiong, Yuan-Zhu,Deng, Chang-Yan,Zuo, Bo,Xie, Hong-Tao,Xu, De-Quan Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.8

The protein encoded by SLC27A2 gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family, and it converts free long-chain fatty acids into fatty acyl-CoA esters, and thereby plays a key role in lipid biosynthesis and fatty acid degradation. In the present study, SLC27A2 located on human chromosome 15 was selected as candidate gene and we isolated and cloned partial fragments of mRNA sequence and genomic fragments of porcine SLC27A2 gene. The coding region of the gene as determined by alignments shared 90% and 82% identity with human and mouse cDNAs, respectively. Detection in LargeWhite and Meishan breeds showed that a single nucleotide polymorphism (SNP) ($A{\rightarrow}G$) existed in exon 7, which caused corresponding amino acid changed for encoding. In LargeWhite pigs it encoded for Val while in Meishan pigs it encoded for Ile, so we developed the PCR-RFLP genotype method for detection of this polymorphism. Association study in 135 $F_2$ reference family indicated that significant correlation existed between the polymorphism and growth and carcass traits.