The prediction of the tooth size in the mixed dentition for Korean

Moon, Sung-Hwan,Kim, Seong-Oh,Yu, Hyung-Seong,Choi, Byung-Jai,Choi, Hyung-Jun,Lee, Jae-Ho 大韓小兒齒科學會 2006 大韓小兒齒科學會誌 Vol.33 No.2

이번 연구의 목적은 혼합치열기 아동에서 미맹출된 견치와 소구치의 크기를 예측하는데 있어서 한국인에 맞는 방정식을 만들기 위함이다. 미맹출 치아의 크기를 예측하는 것은 혼합치열기 교정 진단과 치료계획 수립에 있어서 매우 중요하다. 미맹출된 견치와 소구치 크기를 예측하는 방법은 몇가지가 있지만 그중에서도 가장 흔하게 쓰이는 것이 모이어의 예측표와 다나카와 존스턴의 방정식이 있다. 하지만 그것들은 백인을 위해서 제작된 것이고 치아 크기는 인종에 따라서 다르다고 알려져 있다. 이번 연구에서는 치아크기를 측정하여 하악 영구 절치의 크기 합과 견치 및 소구치의 크기 합 사이의 상관관계를 구하고 회귀방정식을 이용해서 한국인에 맞는 예측표를 만들었다. 연세대학교 치과대학에 재학중인 178명의 한국 학생(남 108명, 여 70명, 평균연령 21.63)을 대상으로 실험하였다. 영구치의 근원심 폭경을 석고모형상에서 calipers를 이용해서 측정하였다. 성별간의 치아 크기는 차이가 있었다(p<0.05). Correlation coefficient는 0.57에서 0.64의 범위였고, standard errors of the estimates 는 여성에서 0.6으로써 남성보다 우수하였다. r^(2)값은 0.27에서 0.41의 범위를 나타내었다. Estimating the size of unerupted teeth is an essential aspect of orthodontic diagnosis and treatment planning in the mixed dentition. Several methods were introduced and used for the prediction. The most common methods among these would be Moyers probability chart and Tanaka and Johnston equations. These are currently used widely, but they were developed for Caucasians. Because there are clear racial differences in teeth size, the objectives of this study were to produce correlation coefficients between the combined mesiodistal widths of the permanent mandibular incisors and those of the canines and premolars for each quadrant, and prediction tables with regression equations, specifically for Korean. 178 young adults (70 women, 108 men, mean age 21.63 years) were selected from the College of Dentistry, Yonsei University, Seoul, Korea. The mesiodistal crown diameters of the permanent teeth were measured with calipers. Significant sexual dimorphism was found in tooth sizes. The correlation coefficients between the total mesiodistal width of the mandibular permanent incisors and those of the maxillary and mandibular canines and premolars were found to be between 0.52 and 0.64. The standard error of the estimatation was better (0.60) for women and the r^(2) values ranged from 0.27 to 0.41 for both sexes, Prediction tables were prepared for Korean. This study showed larger canine and premolar diameters than Tanaka and Johnston's and Moyers' studies which might be due to the racial differences. Further investigations with a larger sample size will be needed for more representative data on the Korean population.

Recurrence of Small Cerebral Aneurysms (< 4 mm) Treated Endovascularly Using Target® NanoTM Coils

Sung Min Kim,Hyun Gon Lee,Byung Sam Choi,Jung Soo Kim,Sungjoon Lee,Hae Yu Kim,Sung Tae Kim,Young-Gyun Jeong,Jin Wook Baek,Hae Woong Jeong,Sung-Chul Jin 대한뇌혈관외과학회 2018 Journal of Cerebrovascular and Endovascular Neuros Vol.20 No.2

Objective : In our series, endovascular coiling with Target® NanoTM coils (Stryker Neurovascular, Fremont, CA, USA) with diameters of 1 or 1.5 mm exhibited favorable technical feasibility in the treatment of small cerebral aneurysms (< 4 mm). However, little is known about the recurrence of small cerebral aneurysms treated using Target® NanoTM coils. We investigated recurrence following the treatment of small cerebral aneurysms using Target® NanoTM coils. Materials and Methods : Between January 2012 and November 2013, 143 patients with 148 small cerebral aneurysms (< 4 mm) were included our study. A total of 135 cerebral aneurysms (91.2%) were unruptured; 45 cerebral aneurysms (30.4%) were treated by endovascular coiling using Target® NanoTM coils. Follow-up radiological images were obtained for 132 cerebral aneurysms (89.2%) over a range of 3 to 58 months (mean, 34.3 months; standard deviation, 14.2). Results : In the group treated with Target® NanoTM coils, radiological outcomes revealed complete occlusion in 33 (73.3%), residual necks in eight (17.8%), and residual sacs in four (8.9%) cases. Follow-up radiological outcomes revealed complete occlusion in 35 (77.8%) and residual necks in four (8.9%) cases that exhibited stable coil masses. In the group that was not treated with Target® NanoTM coils, radiological outcomes revealed complete occlusion in 69 (67%), residual necks in 18 (17.5%), and residual sacs in 16 (15.5%) cases. Follow-up radiological outcomes revealed complete occlusion in 87 (84.5%) and residual necks (5.8%) in six cases that exhibited stable coil masses. No significant differences were observed in the radiological outcomes or follow-up radiological outcomes between the two groups. No recurrences or retreatments occurred in our series. Conclusion : Endovascular treatment using Target® NanoTM coils may be a robust treatment option for small cerebral aneurysms (< 4 mm).

Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II

Choi, Min Hee,Lee, In Kyung,Kim, Gyung Whan,Kim, Bang Ul,Han, Ying-Hao,Yu, Dae-Yeul,Park, Hye Sun,Kim, Kyung Yong,Lee, Jong Seo,Choi, Chulhee,Bae, Yun Soo,Lee, Byung In,Rhee, Sue Goo,Kang, Sang Won Nature Publishing Group 2005 Nature Vol.435 No.7040

Platelet-derived growth factor (PDGF) is a potent mitogenic and migratory factor that regulates the tyrosine phosphorylation of a variety of signalling proteins via intracellular production of H<SUB>2</SUB>O<SUB>2</SUB> (refs 1, 2–3). Mammalian 2-Cys peroxiredoxin type II (Prx II; gene symbol Prdx2) is a cellular peroxidase that eliminates endogenous H<SUB>2</SUB>O<SUB>2</SUB> produced in response to growth factors such as PDGF and epidermal growth factor; however, its involvement in growth factor signalling is largely unknown. Here we show that Prx II is a negative regulator of PDGF signalling. Prx II deficiency results in increased production of H<SUB>2</SUB>O<SUB>2</SUB>, enhanced activation of PDGF receptor (PDGFR) and phospholipase Cγ1, and subsequently increased cell proliferation and migration in response to PDGF. These responses are suppressed by expression of wild-type Prx II, but not an inactive mutant. Notably, Prx II is recruited to PDGFR upon PDGF stimulation, and suppresses protein tyrosine phosphatase inactivation. Prx II also leads to the suppression of PDGFR activation in primary culture and a murine restenosis model, including PDGF-dependent neointimal thickening of vascular smooth muscle cells. These results demonstrate a localized role for endogenous H<SUB>2</SUB>O<SUB>2</SUB> in PDGF signalling, and indicate a biological function of Prx II in cardiovascular disease.

Intravasacular papillary endothelial hyperplasia within sinusoidal hemangioma arsing in the abdomen (초)

( Yu Ri Choi ),( Tae Won Kang ),( Sang Eun Lee ) 대한피부과학회 2011 초록집 Vol.49 No.10

Cone-beam computed tomography for the assessment of root–crown ratios of the maxillary and mandibular incisors in a Korean population

Sung-Hwan Choi,Jung-Suk Kim,Cheol-Soon Kim,Hyung-Seog Yu,Chung-Ju Hwang 대한치과교정학회 2017 대한치과교정학회지 Vol.47 No.1

Objective: This retrospective, cross-sectional study aimed to establish reference data for normal crown and root lengths and the root–crown ratios (R/C ratios) for the mature maxillary and mandibular incisors in a Korean population by using cone-beam computed tomography (CBCT). Methods: We included 672 Korean patients (141 men and 531 women; mean age, 27.2 ± 7.7 years) who underwent CBCT examinations during various dental treatments. Crown and root lengths and the R/C ratios of the maxillary and mandibular incisors were measured using CBCT data, which were analyzed to detect significant differences between demographic factors as well as sagittal and vertical skeletal or occlusal relationships. Results: Teeth of the same type in each half-arch were symmetrical. The mean R/C ratios varied from 1.1 to 1.2 for the maxillary incisors and from 1.3 to 1.4 for the mandibular incisors. Crown and root lengths were greater in men than in women, regardless of tooth type. Root lengths and R/C ratios for the mandibular incisors were significantly greater in patients with skeletal Class II malocclusion or an excessive overjet than in the other patients. The R/C ratios for the mandibular incisors were lower in patients with an open bite than in those with a normal or deep bite. Moreover, the R/C ratios for the mandibular incisors increased with age. Conclusions: The data obtained in our study can serve as reference values for crown and root lengths and the R/C ratios for the maxillary and mandibular incisors in the Korean population.

Influence of crude glycerol on the biomass and lipid content of microalgae

Choi, Hee-Jeong,Yu, Sung-Whan Informa UK (Taylor Francis) 2015 Biotechnology, biotechnological equipment Vol.29 No.3

Cephalometric predictors of future need for orthognathic surgery in Korean patients with unilateral cleft lip and palate despite long-term use of facemask with miniplate

Yu, Sang-Hun,Baek, Seung-Hak,Choi, Jin-Young,Lee, Jong-Ho,Kim, Sukwha,On, Sung-Woon The Korean Association Of Orthodontists 2021 대한치과교정학회지 Vol.51 No.1

Objective: To investigate the cephalometric predictors of the future need for orthognathic surgery in Korean patients with unilateral cleft lip and palate (UCLP) despite long-term use of facemask with miniplate (FMMP). Methods: The sample consisted of 53 UCLP patients treated by a single orthodontist using an identical protocol. Lateral cephalograms were taken before commencement of FMMP therapy (T0; mean age, 10.45 years), after FMMP therapy (T1; mean age, 14.72 years), and at follow-up (T2; mean age, 18.68 years). Twenty-eight cephalometric variables were measured. At T2 stage, the subjects were divided into FMMP-Nonsurgery (n = 33, 62.3%) and FMMP-Surgery (n = 20, 37.7%) groups according to cephalometric criteria (point A-nasion-point B [ANB] < -3°; Wits-appraisal < -5 mm; and Harvold unit difference [HUD] > 34 mm for FMMP-Surgery group). Statistical analyses including discrimination analysis were performed. Results: In FMMP-Surgery group, the forward position of the mandible at T0 stage was maintained throughout the whole stages and Class III relationship worsened with significant growth of the mandibular body and ramus and counterclockwise rotation of the maxilla and mandible at the T1 and T2 stages. Six cephalometric variables at T0 stage including ANB, anteroposterior dysplasia indicator, Wits-appraisal, mandibular body length, HUD, and overjet were selected as effective predictors of the future need for surgical intervention to correct sagittal skeletal discrepancies. Conclusions: Despite long-term use of FMMP therapy, 37.7% of UCLP patients became candidates for orthognathic surgery. Therefore, differential diagnosis is necessary to predict the future need for orthognathic surgery at early age.

A 2.4 /5.2-㎓ Dual Band CMOS VCO using Balanced Frequency Doubler with Gate Bias Matching Network

Sung-Sun Choi,Han-Yeol Yu,Yong-Hoon Kim 대한전자공학회 2009 Journal of semiconductor technology and science Vol.9 No.4

This paper presents the design and measurement of a 2.4/5.2-㎓ dual band VCO with a balanced frequency doubler in 0.18 ㎛ CMOS process. The topology of a 2.4 ㎓ VCO is a cross-coupled VCO with a LC tank and the frequency of the VCO is doubled by a frequency balanced doubler for a 5.2 ㎓ VCO. The gate bias matching network for class B operation in the balanced doubler is adopted to obtain as much power at 2nd harmonic output as possible. The average output powers of the 2.4 ㎓ and 5.2 ㎓ VCOs are -12 ㏈m and -13 ㏈m, respectively, the doubled VCO has fundamental harmonic suppression of -25 ㏈. The measured phase noises at 5 ㎒ frequency offset are -123 ㏈c /㎐ from 2.6 ㎓ and -118 ㏈c /㎐ from 5.1 ㎓. The total size of the dual band VCO is 1.0 ㎜×0.9 ㎜ including pads.

Engineering the xylose‐catabolizing Dahms pathway for production of poly( <small>D</small> ‐lactate‐ <i>co</i> ‐glycolate) and poly( <small>D</small> ‐lactate‐ <i>co</i> ‐glycolate‐ <i>co</i> ȁ

Choi, So Young,Kim, Won Jun,Yu, Seung Jung,Park, Si Jae,Im, Sung Gap,Lee, Sang Yup John Wiley and Sons Inc. 2017 Microbial biotechnology Vol.10 No.6

<P><B>Summary</B></P><P>Poly(lactate‐<I>co</I>‐glycolate), PLGA, is a representative synthetic biopolymer widely used in medical applications. Recently, we reported one‐step direct fermentative production of PLGA and its copolymers by metabolically engineered <I>Escherichia coli</I> from xylose and glucose. In this study, we report development of metabolically engineered <I>E. coli</I> strains for the production of PLGA and poly(<SMALL>D</SMALL>‐lactate‐<I>co</I>‐glycolate‐<I>co</I>‐<SMALL>D</SMALL>‐2‐hydroxybutyrate) having various monomer compositions from xylose as a sole carbon source. To achieve this, the metabolic flux towards Dahms pathway was modulated using five different synthetic promoters for the expression of <I>Caulobacter crescentus</I> XylBC. Further metabolic engineering to concentrate the metabolic flux towards <SMALL>D</SMALL>‐lactate and glycolate resulted in production of PLGA and poly(<SMALL>D</SMALL>‐lactate‐<I>co</I>‐glycolate‐<I>co</I>‐<SMALL>D</SMALL>‐2‐hydroxybutyrate) with various monomer fractions from xylose. The engineered <I>E. coli</I> strains produced polymers containing 8.8–60.9 mol% of glycolate up to 6.93 g l<SUP>−1</SUP> by fed‐batch cultivation in a chemically defined medium containing xylose. Finally, the biocompatibility of poly(<SMALL>D</SMALL>‐lactate‐<I>co</I>‐glycolate‐<I>co</I>‐<SMALL>D</SMALL>‐2‐hydroxybutyrate) was confirmed by live/dead assay using human mesenchymal stem cells.</P>

Plasma cell vulvitis

( Sung Soo Han ),( Hyun Seok Choi ),( Jae Min Shin ),( Young Gyun Kim ),( Joung Soo Kim ),( Hee Joon Yu ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1

Plasma cell vulvitis is a chronic inflammatory disease of vulva characterized by plasma cell infiltration during the lifetime of a woman. It can be seen especially during the climacterium. The most common symptoms associated with plasma cell vulvitis are pruritus, pain, burning sensation and dyspareunia. The specific cause of this condition is unknown and suggested predisposing factors include warmth, friction, poor hygiene, herpes simplex infection and other chronic infections. A 53-year-old woman presented with erythematous to whitish patch and plaque with severe itching on vulva for several years. Histopathological examination revealed perivascular infiltration of inflammatory cells mainly with plasma cells in superficial dermis.