Research on User-personalized Image Retrieval Method

Yu Song,Jing-fei Ren,Mao-Zhu Jin,Pei-Yu Ren 보안공학연구지원센터 2014 International Journal of Multimedia and Ubiquitous Vol.9 No.6

Polyvinylidene Fluoride Electrospun Fibers Loaded TiO2 for Photocatalytic Degradation and Oil/Water Separation

Fei Sun,Hai-Tao Ren,Shih-Yu Huang,Ting-Ting Li,Hao-Kai Peng,Qi Lin,Ching-Wen Lou,Jia-Horng Lin 한국섬유공학회 2020 Fibers and polymers Vol.21 No.7

In this study, electrospun polyvinylidene fluoride (PVDF)-based nanofibrous membranes embedding TiO2 wereprepared and used for photocatalytic degradation and oil/water separation. The nanofibrous membranes were characterizedby scanning electron microscopy (SEM), transmission electronic microscope (TEM), X-ray diffraction (XRD), Fouriertransform infrared spectroscopy (FTIR) spectroscopy, thermal performance analysis, and oil/water separation analysis. Andthe degradation of rhodamine B dye was also investigated. Results showed that the fiber diameter and thermal stability of themembranes decreased with the increasing of TiO2. Meanwhile, the fiber surface roughness and specific surface areaincreased. The analysis of TEM, XRD and FTIR indicated that TiO2 existed in the PVDF membranes. When the TiO2 contentwas 12 %, the fiber diameter of the membranes was about 110 nm, and the photocatalytic degradation of rhodamine B dyeefficiency was up to 97 %. The reaction rate constant was 0.02057 min-1. At 0.01 MPa vacuum, oil separated from watereffectively, which proves that separation can be easily conducted with a low energy cost. Thus, the prepared membranes havea very high application prospect in the purification of reclaimed water and separation of oil and water.

The Modeling Methods of Heavy NC Machine Tool Bolt Joint Based on Virtual Media

Ren Sheng-Le,Gao Fei,Dai Ye,Wang Peng,Cheng Tian-Yu 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.9

The Department of Heavy NC machine tool has a great influence on the performance of machine tools. The 30%-50% static stiffness, more than 50% of the dynamic stiffness depends on the combining part, and the influence on damping reached 90%.Machine tool with the Department of static and dynamic performance directly determines the accuracy and reliability of Heavy NC machine tool. Therefore, in conjunction with the Department of research and design of Heavy NC machine tool is very important. In this paper, based on Hertz contact theory, the contact at the micro level, considering the combination form of machine tool, and the machine joints as a virtual media simulation, a combination of virtual media framework, and calculation of characteristic parameters of the virtual material, then use the ANSYS Workbench to solve the combination of the natural frequency of the whole, the first five order modal extraction. Using modal test technology, get the specimens of natural frequency and damping of the true value, natural frequency are compared with theory, prove the formula of virtual media is reliable, can be used in the modeling of heavy machine tool.

Protocadherin alpha 3 inhibits lung squamous cell carcinoma metastasis and epithelial-mesenchymal transition

Tao Yu,Fei Liu,Chang Liu,Yongyu Liu,Jianhui Jia,Yanan Liu,Yi Ren 한국유전학회 2022 Genes & Genomics Vol.44 No.2

Background: Lung squamous cell carcinoma (LUSC) is associated with poor clinical prognosis and lacks available targeted therapy. Given that the major threat of cancer is metastasis, delineation of the molecular mechanism underlying it would help devise therapeutic strategies. Objective: To investigate the functional role of protocadherin alpha 3 (PCDHA3) in LUSC, as well as investigate the underlying molecular mechanism. Methods: Data for PCDHA3 expression and clinical information in The Cancer Genome Atlas (TCGA) were extracted and analyzed in the UALCAN platform. Expression levels of PCDHA3 in LUSC cell lines were analyzed via RT-PCR and western blot. Overexpression of PCDHA3 was conducted via plasmid transfection. CCK-8 and cell cycle assays were utilized to investigate effect of PCDHA3 on cell proliferation. Transwell assay was used to detect migration and invasion. The underlying mechanism was demonstrated via western blot analysis. Results: Our data indicate that PCDHA3 was low expressed in three kinds of LUSC cell lines and best in H520 cells. Furthermore, overexpression of PCDHA3 could significantly impair LUSC cells proliferation, invasion and migration. Moreover, PCHDA3 repressed the biomarkers of mesenchymal (N-cadherin, fibronectin and vimentin) and increased expression of epithelial markers (E-cadherin and α-catenin). On the other hand, PCDHA3 overexpression partially blocked epithelial-mesenchymal transition. Conclusions: PCDHA3 suppressed the LUSC cells proliferation, invasion and migration via inhibiting the expression of EMT signatures, suggesting that PCDHA3 could serve as a valuable therapeutic target for LUSC therapy.

Clinical Study of Thalidomide Combined with Dexamethasone for the Treatment of Elderly Patients with Newly Diagnosed Multiple Myeloma

Chen, Hai-Fei,Li, Zheng-Yang,Tang, Jie-Qing,Shen, Hong-Shi,Cui, Qing-Ya,Ren, Yong-Ya,Qin, Long-Mei,Jin, Ling-Juan,Zhu, Jing-Jing,Wang, Jing,Ding, Jie,Wang, Ke-Yuan,Yu, Zi-Qiang,Wang, Zhao-Yue,Wu, Tian Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

Objective: To investigate the relationship between the efficacy and safety of different doses of thalidomide (Thal) plus dexamethasone (Dex) as the initial therapy in elderly patients with newly diagnosed multiple myeloma (MM). Methods: Clinical data of 28 elderly patients with newly diagnosed MM who underwent the TD regimen as the initial therapy were analyzed retrospectively. The patients were divided into two groups according to the maximal sustained dose of Thal: lower dose (group A) and higher dose (group B). The overall response rate (ORR), progression free survival (PFS), overall survival (OS), and adverse events (AES) were compared between the two groups. Results: A total of 28 patients were followed up with a median of 18 months. The ORR was 60.1%. The median response time and PFS were 2.0 and 17.0 months, respectively. The mean sustained dose of Thal in group B was significantly higher than group A (292.9 mg v 180.4 mg, P=0.01). There was no significantly difference in ORR (57.1% v 64.3%, P=1.00) and PFS (9.63months v 17.66 months, P=0.73) between groups A and B. During the follow up, only five patients died (<40%) and, therefore, median OS values were not available. It is estimated, however, that the mean survival time in the two groups was 35.6 and 33.4 months (P>0.05), respectively. All of the patients tolerated the treatment well. The incidence of AES in patients with a grading above 3 in group B was significantly higher than in group A (P=0.033). Conclusions: The TD regimen results in a high response rate and manageable AES as the initial therapy in elderly patients with MM. TD should be considered as the front line regimen for the treatment of elderly patients with MM in areas with financial constraints. The clinical response can be achieved at a low dose Thal with minimal toxicity.

Security Analysis of Speech Perceptual Hashing Authentication Algorithm

Zhang Qiu-yu,Ren Zhan-wei,Xing Peng-fei,Huang Yi-bo,Yu Shuang 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.1

Speech perceptual hashing authentication algorithm is an efficient method for content integrity authentication and identity authentication. But the algorithm becomes transparent under the principle of Kerckhoffs which makes the algorithm unsafe. In this paper, the algorithm is encrypted under the principle of Kerckhoffs to protect the security of the algorithm. Then the specific link that won’t affect the performance of the algorithm is identified through the experiments. Next, this paper analyzes the security of the encrypted algorithm based on the concept of Shannon unicity distance. The unicity distance is figured out finally based on the experiments. That is to say, the algorithm loses its security even though the algorithm has been encrypted. Under this circumstances, the most important thing is to continue keeping the safety of the algorithm. Therefore, this paper proposed an efficient random secret key method to guarantee the safety of the algorithm after the unicity distance is figured out.

Bioaugmentation Treatment of Mature Landfill Leachate by New Isolated Ammonia Nitrogen and Humic Acid Resistant Microorganism

( Da Hai Yu ),( Ji Yu Yang ),( Fei Teng ),( Li Li Feng ),( Xue Xun Fang ),( He Jun Ren ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.7

The mature landfill leachate, which is characterized by a high concentration of ammonia nitrogen (NH3-N) and humic acid (HA), poses a challenge to biotreatment methods, due to the constituent toxicity and low biodegradable fraction of the organics. In this study, we applied bioaugmentation technology in landfill leachate degradation by introducing a domesticated NH3-N and HA resistant bacteria strain, which was identified as Bacillus cereus (abbreviated as B. cereus Jlu) and Enterococcus casseliflavus (abbreviated as E. casseliflavus Jlu), respectively. The isolated strains exhibited excellent tolerant ability for NH3-N and HA and they could also greatly improved the COD (chemical oxygen demand), NH3-N and HA removal rate, and efficiency of bioaugmentation degradation of landfill leachate. Only 3 days was required for the domesticated bacteria to remove about 70.0% COD, compared with 9 days`` degradation for the undomesticated (autochthonous) bacteria to obtain a similar removal rate. An orthogonal array was then used to further improve the COD and NH3-N removal rate. Under the optimum condition, the COD removal rate in leachate by using E. casseliflavus Jlu and B. cereus Jlu increased to 86.0% and 90.0%, respectively after, 2 days of degradation. The simultaneous removal of NH3-N and HA with more than 50% and 40% removal rate in leachate by employing the sole screened strain was first observed.

Identification of novel rheumatoid arthritis-associated MiRNA-204-5p from plasma exosomes

Wu Long-Fei,Zhang Qin,Mo Xing-Bo,Lin Jun,Wu Yang-Lin,Lu Xin,He Pei,Wu Jian,Guo Yu-Fan,Wang Ming-Jun,Ren Wen-Yan,Deng Hong-Wen,Lei Shu-Feng,Deng Fei-Yan 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

Rheumatoid arthritis (RA) is an autoimmune disease characterized by infiltration of immune cells in the synovium. However, the crosstalk of immune cells and synovial fibroblasts is still largely unknown. Here, global miRNA screening in plasma exosomes was carried out with a custom microarray (RA patients vs. healthy controls = 9:9). A total of 14 exosomal miRNAs were abnormally expressed in the RA patients. Then, downregulated expression of exosomal miR-204-5p was confirmed in both the replication (RA patients vs. healthy controls = 30:30) and validation groups (RA patients vs. healthy controls = 56:60). Similar to the findings obtained in humans, a decreased abundance of exosomal miR-204-5p was observed in mice with collagen-induced arthritis (CIA). Furthermore, Spearman correlation analysis indicated that plasma exosomal miR-204-5p expression was inversely correlated with disease parameters of RA patients, such as rheumatoid factor, erythrocyte sedimentation rate, and C-reactive protein. In vitro, our data showed that human T lymphocytes released exosomes containing large amounts of miR-204-5p, which can be transferred into synovial fibroblasts, inhibiting cell proliferation. Overexpression of miR-204-5p in synovial fibroblasts suppressed synovial fibroblast activation by targeting genes related to cell proliferation and invasion. In vivo assays found that administration of lentiviruses expressing miR-204-5p markedly alleviated the disease progression of the mice with CIA. Collectively, this study identified a novel RA-associated plasma exosomal miRNA-204-5p that mediates the communication between immune cells and synovial fibroblasts and can be used as a potential biomarker for RA diagnosis and treatment.

New Method to Improve the Secondary Path Modeling Accuracy for Active Noise Control Systems

Shan-zhen Yi,Ren-yuan Fei,Da-sen Zhou,Tai-wen Liu,Jian-ping Yu,Jin-feng Yang,Kui-cheng Gong 한국소음진동공학회 2003 한국소음진동공학회 국제학술대회논문집 Vol.2003 No.8

Ground Motion Frequency Insensitivity of Bearing-Supported Pedestrian Bridge with Viscous Dampers

Qunfeng Liu,Shimin Zhu,Wenshan Yu,Xing Wu,Fei Song,Xiang Ren 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.7

This work studies the dynamic responses of bearing-supported pedestrian bridges with Y-shaped piers and various deck widths under harmonic ground motions. To fulfill the immediate occupancy performance objective, the dynamic responses of bridges with linear or nonlinear viscous dampers are evaluated by performing nonlinear time-history analyses. The results show that the maximum transverse displacements of girder and pier top in original bridges are closely dependent on the characteristic period of ground motion. The installation of linear viscous dampers between steel girder and Y-shaped piers can effectively improve the seismic performance of bridges and hence reduce the corresponding shear demand of bearings. Further parametric studies show that, with optimal damping coefficient and velocity exponent, the seismic performances of bridges with viscous dampers can be insensitive to the characteristic period of ground motion.