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Comparisons of Effects of Biman-tang according to Administration Period in Childhood Obesity
임영권,민서림,김희만,허광욱,이훈,이진수,김호철,박재우,박히준,Lim, Youngkwern,Min, Seorim,Kim, Heeman,Hur, Kwang-Wook,Lee, Hoon,Lee, Jinsoo,Kim, Hocheol,Park, Jae-Woo,Park, Hi-Joon The Association of Korean Oriental Pediatrics 2013 대한한방소아과학회지 Vol.27 No.4
Objectives The purpose of this study is to investigate the safety and effect of Biman-tang (BMT) on two different administration periods in the treatment of childhood overweight and obesity. Methods In retrospective study, 39 overweight and obese ($85^{th}$ percentile ${\leq}$ Body Mass Index (BMI)) children were treated with BMT from January 2006 to April 2013 at Korean Medical Clinic in Suwon, Korea. The primary outcomes were the changes in BMI and Obesity Index (OI) from baseline to the treatment groups. Secondary outcomes included the changes in height, weight and safety of the medicine. Comparisons of BMI, OI, height and weight between the short-period (SP) treatment group and the long-period (LP) treatment group were done by using ANCOVA. Results The change of the mean of BMI ($-0.5{\pm}0.6kg/m^2$ vs $-1.4{\pm}0.8kg/m^2$, respectively; p=0.003) and OI ($-3.6{\pm}3.9%$ vs $-9.7{\pm}4.7%$, respectively; p<0.001) showed significant reduction both in SP (n=16) and LP treatment group (n=23). The mean height showed no significant difference in both groups. The mean weight of LP treatment group showed significant reduction compared to SP treatment group ($-0.2{\pm}1.3kg$ vs $-1.6{\pm}1.6kg$, respectively; p=0.006). Most of the children were compliant to the medication and no serious adverse events were found in two groups. Conclusions These findings emphasize that BMT is effective in the treatment of childhood obesity and it requires at least 45 days of treatment for the best result.
성조숙증으로 진단된 여자 환아에서 호르몬 수치가 개선된 치험 1례
임영권,허광욱,박송이,서경석,천상렬,이석진,이훈,김호철,Lim, Youngkwern,Hur, Kwang-Wook,Park, Song Yi,Suh, Kyeung Suk,Chun, Sang Yeol,Lee, Suk Jin,Lee, Hoon,Kim, Hocheol 대한한방소아과학회 2014 대한한방소아과학회지 Vol.28 No.4
Objectives The purpose of this study is to find out how taking oriental herbal medicine may affect the sex hormone levels in a patient who was diagnosed with prematurity. Methods We prescribed 120 cc of oriental herbal medicine twice daily for a month to a patient suspected of the precocious puberty due to 11 pg/ml of the estradiol level. Upon finishing the course of oriental herbal medicine, the patient was retested for the follicular stimulating hormone, luteinizng hormone and estradiol levels. Results After administration, all levels of luteininzing hormone, follicular stimulating hormone and estradiol were decreased. There was no diagnosable evidence for the idiopathic central precocious puberty in the gonadotropin releasing hormone stimulation. Conclusions Oriental herbal medicine is a good alternative treatment of choice for the precocious puberty. However, more in-depth studies are to be followed.