Association between the TGFBR2 G-875A Polymorphism and Cancer Risk: Evidence from a Meta-analysis

Huang, Yong-Sheng,Zhong, Yu,Yu, Long,Wang, Lin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

Disrupted transforming growth factor-${\beta}$ (TGF-${\beta}$) signaling is involved in the development of various types of cancer and the TGF-${\beta}$ receptor II (TGFBR2) is a key mediator of TGF-${\beta}$ growth inhibitory signals. It is reported that the G-875A polymorphism in TGFBR2 is implicated in risk of various cancers. However, results for the association between this polymorphism and cancer remain conflicting. To derive a more precise estimation, a meta-analysis of 3,808 cases and 4,489 controls from nine published case-control studies was performed. Our analysis indicated that G-875A is associated with a trend of decreased cancer risk for allele A versus(vs.) allele G [odds ratio (OR) =0.64, 95% confidence intervals (CI): 0.55-0.74], as well as for both dominant model [(A/A+G/A) vs. G/G, OR=0.76, 95% CI: 0.64-0.90] and recessive model [A/A vs. (G/G+G/A), OR=0.74, 95% CI: 0.59-0.93). However, larger scale primary studies are required to further evaluate the interaction of TGFBR2 G-875A polymorphism and cancer risk in specific cancer subtypes.

Synthesis and field emission of patterned ZnO nanorods

Yong Huang,Ke Yu,Ziqiang Zhu 한국물리학회 2007 Current Applied Physics Vol.7 No.6

a low temperature of 500.C. The patterned ZnO nanorod arrays, a unit area is of. 400 · 100 l m2, are synthesized via vapor phase trans-port method. The surface morphology and composition of the as-synthesized ZnO nanorods are characterized by means of scanningelectron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). The mechanism of formation of ZnO nanorods is alsol m at the current density of 0.1l A/cm2 and a low threshold eld of 6.2 V/l m at the current density of 1 mA/cm2. So this approach musthave a potential application of fabricating micropatterned oxide thin lms used in FE-based at panel displays.

Hybrid adaptive neuro fuzzy inference system for optimization mechanical behaviors of nanocomposite reinforced concrete

Huang, Yong,Wu, Shengbin Techno-Press 2022 Advances in nano research Vol.12 No.5

The application of fibers in concrete obviously enhances the properties of concrete, also the application of natural fibers in concrete is raising due to the availability, low cost and environmentally friendly. Besides, predicting the mechanical properties of concrete in general and shear strength in particular is highly significant in concrete mixture with fiber nanocomposite reinforced concrete (FRC) in construction projects. Despite numerous studies in shear strength, determining this strength still needs more investigations. In this research, Adaptive Neuro-Fuzzy Inference System (ANFIS) have been employed to determine the strength of reinforced concrete with fiber. 180 empirical data were gathered from reliable literature to develop the methods. Models were developed, validated and their statistical results were compared through the root mean squared error (RMSE), determination coefficient (R²), mean absolute error (MAE) and Pearson correlation coefficient (r). Comparing the RMSE of PSO (0.8859) and ANFIS (0.6047) have emphasized the significant role of structural parameters on the shear strength of concrete, also effective depth, web width, and a clear depth rate are essential parameters in modeling the shear capacity of FRC. Considering the accuracy of our models in determining the shear strength of FRC, the outcomes have shown that the R² values of PSO (0.7487) was better than ANFIS (2.4048). Thus, in this research, PSO has demonstrated better performance than ANFIS in predicting the shear strength of FRC in case of accuracy and the least error ratio. Thus, PSO could be applied as a proper tool to maximum accuracy predict the shear strength of FRC.

“Medicine of the Grassroots”: Korean Herbal Medicine Industry and Consumption during the Japanese Colonial Period

HUANG Yong-yuan 대한의사학회 2020 醫史學 Vol.29 No.1

One Atomic Beam as a Detector of Classical Harmonic Vibrations with Micro Amplitudes and Low Frequencies

Yong-Yi Huang 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.64 No.6

We propose a simplest detector of harmonic vibrations with micro amplitudes and low frequencies,i.e. a detector consisting of one atomic beam. Here, the atomic beam is induced by a plane harmonicwave and has classical collective harmonic vibrations, whose vibrant directions are perpendicularto the wave vectors of the atomic beam. Compared with a detector consisting of an atomic Mach-Zehnder interferometer, the new detector has two advantages: (1) it is suitable for the detection ofharmonic vibrations induced either by a longitudinal plane harmonic wave or by using a transverseplane harmonic wave: (2) the quantum noise fluctuation of the atomic beam is exactly zero. Wepresent the principle for detecting classical harmonic vibrations with micro amplitudes and lowfrequencies by using the new detector. The frequency of a classical harmonic vibration with a microamplitude can be evaluated by measuring the variations in the mean numbers of atoms arriving atthe atomic detector.

Evaluation of Microvascular Anastomosis Using Real-Time, Ultra–High-Resolution, Fourier Domain Doppler Optical Coherence Tomography

Huang, Yong,Tong, Dedi,Zhu, Shan,Wu, Lehao,Mao, Qi,Ibrahim, Zuhaib,Lee, W. P. Andrew,Brandacher, Gerald,Kang, Jin U. Williams & Wilkins 2015 Plastic and reconstructive surgery Vol.135 No.4

BACKGROUND:: Evolution in microsurgical techniques and tools has paved the way for supermicrosurgical anastomoses, with vessel diameters often approaching below 0.8 mm in the clinical realm and even smaller (0.2 to 0.3 mm) in murine models. Several imaging and monitoring devices have been introduced for postoperative monitoring, but intraoperative guidance, assessment, and predictability have remained limited to binocular optical microscopy and the surgeon’s experience. The authors present a high-resolution, real-time, three-dimensional imaging modality for intraoperative evaluation of luminal narrowing, thrombus formation, and flow alterations. METHODS:: An imaging modality that provides immediate, in-depth, high-resolution, three-dimensional structure view and flow information of the anastomosed site, called phase-resolved Doppler optical coherence tomography, was developed. Twenty-two mouse femoral artery anastomoses and 17 mouse venous anastomoses were performed and evaluated. Flow status, vessel inner lumen three-dimensional structure, and early thrombus detection were analyzed based on imaging results. Predictions formed correlated with actual long-term surgical outcomes. Eventually, four cases of mouse orthotopic limb transplantation were carried out, and predicted long-term patency based on imaging results was confirmed by actual results. RESULTS:: The assessments based on high-resolution three-dimensional visualization of the vessel flow status and inner lumen provided by phase-resolved Doppler optical coherence tomography show 92 percent sensitivity and 90 percent specificity for arterial anastomoses and 90 percent sensitivity and 86 percent specificity for venous anastomoses. CONCLUSIONS:: Phase-resolved Doppler optical coherence tomography is an effective evaluation tool for microvascular anastomosis. It can predict the long-term vessel patency with high sensitivity and specificity.

Controllable Synthesis and Photocatalytic Properties of C-doped BiVO4 with Self-Heterostructure Under Different Light Sources

Yong Wang,Jianfeng Huang,Guoqiang Tan,Jing Huang,Lili Zhang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.1

C-doped BiVO4 with self-heterostructure were synthesized via a facile one-step microwave-hydrothermal route at different reaction temperatures and reaction times. The crystal structure,morphology and photophysical properties of the samples were characterized by X-ray diffraction (XRD), field-emission scanning electron microscope (FE-SEM) and UV-Vis techniques. The photocatalytic properties of the samples were evaluated by the decolorization of rhodamine B under ultraviolet light or simulated visible light irradiation. It was found that pure BiVO4 polyhedrons had a monoclinic structure while C-doped BiVO4 had self-heterostructure with both monoclinic and tetragonal phase. This mixed-phase structure exhibited higher activity than monoclinic structure under ultraviolet light irradiation while monoclinic C-doped BiVO4 had better photocatalytic property under simulated visible light irradiation. The selectivity of the light source with different C-doped BiVO4 self-heterostructures was also discussed in this work.

Giant Ganglioneuroma of Thoracic Spine : A Case Report and Review of Literature

Huang, Yong,Liu, Lidi,Li, Qiao,Zhang, Shaokun The Korean Neurosurgical Society 2017 Journal of Korean neurosurgical society Vol.60 No.3

Ganglioneuroma (GN) is a rare benign tumor of neural crest origin usually found in the abdomen, but may occasionally present at uncommon sites including the cervical, lumbar, or sacral spine. However, GNs of thoracic spine are extremely rare. In this report, we describe a 12-year-old girl with giant GN in the thoracic spine, who underwent successful resection (T1-4 level) of the tumor. Histopathological examination confirmed the diagnosis. GN should be considered in the differential diagnosis of any paraspinal mass. A high index of suspicion and correlation of clinico-radiological findings is necessary in differentiating a large benign tumor from a malignant growth. Complete surgical excision is the treatment of choice; however tumor size and location need to be considered for the surgical approach (one-step or multiple surgeries). Close follow-up after surgery is mandatory.

Planet Versions of the State of Schr¨odinger’s Cat Prepared by Using Quantum Measurements

Yong-Yi Huang 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.68 No.8

A classical charged particle travels along a circular orbit and interacts with a silver atom in its ground state fixed at the center of the circle through Biot-Savart coupling. We find that if the silver atom initially lies in a spin superposition state of valence electron, in the co-rotating frame of reference the projected measurements of the spin of silver’s valence electron along the z direction determine the rotational direction, and the projected measurements of that spin along the x or the y direction yield planet versions of the state of Schr¨odinger’s cat.

On nonlinear deflection analysis and dynamic response of sandwich plates based on a numerical method

Yong Huang,Zengshui Liu,Shihan Ma,Sining Liu,Rui Yu 국제구조공학회 2023 Steel and Composite Structures, An International J Vol.47 No.1

Nonlinear forced vibration properties of three-layered plates containing graphene platelets (GPL) filled skins and an auxetic core have been inquired within the present paper. Owning reduced weight as well as reduced stiffness, rectangle-shaped auxetic cores have been frequently made from novel techniques such as additive manufacturing. Here, the rectangle shape core is amplified via the graphene-filled layers knowing that the layers possess uniform and linear graphene gradations. The rectangle shape core has the equivalent material specifications pursuant to relative density value. The sandwich plate is formulated pursuant to Kirchhoff plate theory while a numerical trend has been represented to discretize the plate equations. Next, an analytical trend has been performed to establish the deflection-frequency plots. Large deflections, core density and GPL amplification have showed remarkable impacts on dynamic response of three-layered plates.