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Preparation and antimicrobial assay of ceramic brackets coated with TiO₂ thin films
Shuai Cao,Ye Wang,Lin Cao,Yu Wang,Bingpeng Lin,Wei Lan,Baocheng Cao 대한치과교정학회 2016 대한치과교정학회지 Vol.46 No.3
Objective: Different methods have been utilized to prevent enamel demineralization and other complications during orthodontic treatment. However, none of these methods can offer long-lasting and effective prevention of orthodontic complications or interventions after complications occur. Considering the photocatalytic effect of TiO₂ on organic compounds, we hoped to synthesize a novel bracket with a TiO₂ thin film to develop a photocatalytic antimicrobial effect. Methods: The sol-gel dip coating method was used to prepare TiO₂ thin films on ceramic bracket surfaces. Twenty groups of samples were composed according to the experimental parameters. Crystalline structure and surface morphology were characterized by X-ray diffraction and scanning electron microscopy, respectively; film thickness was examined with a surface ellipsometer. The photocatalytic properties under ultraviolet (UV) light irradiation were analyzed by evaluating the degradation ratio of methylene blue (MB) at a certain time. Antibacterial activities of selected thin films were also tested against Lactobacillus acidophilus and Candida albicans . Results: Films with 5 coating layers annealed at 700°C showed the greatest photocatalytic activity in terms of MB decomposition under UV light irradiation. TiO₂ thin films with 5 coating layers annealed at 700°C exhibited the greatest antimicrobial activity under UV-A light irradiation. Conclusions: These results provide promising guidance in prevention of demineralization by increasing antimicrobial activities of film coated brackets.
Ye Guiwen,Li Jinteng,Yu Wenhui,Xie Zhongyu,Zheng Guan,Liu Wenjie,Wang Shan,Cao Qian,Lin Jiajie,Su Zepeng,Li Dateng,Che Yunshu,Fan Shuai,Wang Peng,Wu Yanfeng,Shen Huiyong 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Improving health and delaying aging is the focus of medical research. Previous studies have shown that mesenchymal stem cell (MSC) senescence is closely related to organic aging and the development of aging-related diseases such as osteoarthritis (OA). m6A is a common RNA modification that plays an important role in regulating cell biological functions, and ALKBH5 is one of the key m6A demethylases. However, the role of m6A and ALKBH5 in MSC senescence is still unclear. Here, we found that the m6A level was enhanced and ALKBH5 expression was decreased in aging MSCs induced by multiple replications, H2O2 stimulation or UV irradiation. Downregulation of ALKBH5 expression facilitated MSC senescence by enhancing the stability of CYP1B1 mRNA and inducing mitochondrial dysfunction. In addition, IGF2BP1 was identified as the m6A reader restraining the degradation of m6A-modified CYP1B1 mRNA. Furthermore, Alkbh5 knockout in MSCs aggravated spontaneous OA in mice, and overexpression of Alkbh5 improved the efficacy of MSCs in OA. Overall, this study revealed a novel mechanism of m6A in MSC senescence and identified promising targets to protect against aging and OA.
An immunoassay using biotinylated single-walled carbon nanotubes as Raman biomarkers
Cao, Chengfan,Kim, Jung Heon,Kwon, Ye-Jin,Kim, Young-Jin,Hwang, Eung-Soo,Baik, Seunghyun Royal Society of Chemistry 2009 The Analyst Vol.134 No.7
<P>A new immunoassay with biotinylated single-walled carbon nanotubes as persistent, non-photobleaching Raman biomarkers demonstrated excellent sensitivity and specificity.</P> <P>Graphic Abstract</P><P>A new immunoassay with biotinylated single-walled carbon nanotubes as persistent, non-photobleaching Raman biomarkers demonstrated excellent sensitivity and specificity. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b900501n'> </P>
Functional Roles of Long Non-coding RNA in Human Breast Cancer
Ye, Ni,Wang, Bin,Quan, Zi-Fang,Cao, San-Jie,Wen, Xin-Tian,Huang, Yong,Huang, Xiao-Bo,Wu, Rui,Ma, Xiao-Ping,Yan, Qi-Gui Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15
The discovery of long noncoding RNA (LncRNA) changes our view of transcriptional and posttranscriptional regulation of gene expression. With application of new research techniques such as high-throughput sequencing, the biological functions of LncRNAs are gradually becoming to be understood. Multiple studies have shown that LncRNAs serve as carcinogenic factors or tumor suppressors in breast cancer with abnormal expression, prompts the question of whether they have potential value in predicting the stages and survival rate of breast cancer patients, and also as therapeutic targets. Focusing on the latest research data, this review mainly summarizes the tumorigenic mechanisms of certain LncRNAs in breast cancer, in order to provide a theoretical basis for finding safer, more effective treatment of breast cancer at the LncRNA molecular level.
Fuzzy adaptive PID control method for multi-mecanum-wheeled mobile robot
Guoqiang Cao,Xinyu Zhao,Changlong Ye,Suyang Yu,Bangyu Li,Chunying Jiang 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.4
Mecanum-wheeled mobile robots are widely used because they can easily realize omnidirectional movement and have flexible movement characteristics. However, existing mecanum-wheeled robots generally have problems of low movement accuracy and poor stability. Structural optimization method can improve the movement accuracy and stability of mecanum-wheeled robots, but it cannot solve the problem fundamentally. In this study, the method of geometric modeling is applied to deduce the parameters kinematic error e, slip factor μ, and overturning angle λ, all of which have an effect on the movement accuracy and stability of the robot. Combined with the advantages of PID and fuzzy control, a fuzzy adaptive PID control method is proposed. The experimental prototype of the eight-mecanum-wheeled omnidirectional mobile robot is built to carry out the trajectory tracking control experiment, and the superiority in the fuzzy adaptive PID control method is verified.
Jing Ye,Yasutaka Nakashima,Takao Watanabe,Masatoshi Seki,Bo Zhang,Quanquan Liu,Yuki Yokoo,Yo Kobayashi,Qixin Cao,Masakatsu G. Fujie 제어로봇시스템학회 2013 제어로봇시스템학회 국제학술대회 논문집 Vol.2013 No.10
In consideration of a large proportion of stroke survivors with persistent deficits, current interventions have limited ability to restore normal motor function. We propose a gait training system for gait rehabilitation of hemiplegic patients with convalescent stroke. It consists of a functional electrical stimulation (FES) device which is used to influence the gait pattern instantly to improve the quality of the gait, and a treadmill with two separated belts. The stimulus triggers from the FES could be controlled automatically by the subject`s gait phase determination, including stance phase and swing phase. Gait phase could be estimated and recognized through observing current value variation of the treadmill motor during the subject’s walking on the treadmill belts. In this paper, we have preliminarily tested the feasibility of the proposed method through hemiplegic simulation experiments. Also, Tibialis Anterior (TA) and quadriceps on the hemiplegic side were successfully stimulated by the expected FES stimuli during gait.
Research of Condition Health Sample Model based on Bootstrap Method for Hydropower Unit
Zhou Ye,Tang Shu,Cao Dengfeng,Pan Luoping 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.3
In this paper, long term trend data from condition monitoring systems of hydropower units was used to separate to grid cells based on the water head and active power, and to build the health sample model for abnormal evaluation. For the problem of insufficient monitoring samples on non-rated operating conditions, Bootstrap method is introduced for sample expansion and confidence interval calculation, thereby to achieve limit optimize settings of health sample of hydropower unit condition data, which is more approximate to practical engineering than normal approximation method, and has achieved a good result.
Turbine Efficiency Measurement by Thermodynamic Test Method
Zhou Ye,Pan Luoping,Cao Dengfeng 한국유체기계학회 2019 International journal of fluid machinery and syste Vol.12 No.4
According to the requirement of IEC60041, the paper introduces various turbine efficiency measurement methods, and analyzes their feature and difficulties, then gives a detailed introduction for the principle and requirement of thermodynamic test method. With an example of turbine efficiency test implemented in Costa Rica, the paper gives a complete test procedure and data calculation for thermodynamic method. Finally, a comparison and verification among thermodynamic method, ultrasonic method and Winter-Kennedy method has been made, the result shows that it has great advantage and effectivity for thermodynamic method when using in flow measurement of high water head turbine.
Feng Ye,Yanpeng Cao,Weiwei Han,Yakun Yang,Yuancheng Feng,Peng Liu,Chao Xu,Xiaoze Du,양우철,Liu Guicheng 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.3
A highly active RuO2IrO2 electrocatalyst was developed via dip-coating/calcination method for oxygen evolution reaction (OER). The catalyst on Ti substrate with a 7/3 molar ratio between Ru and Ir showed the highest electrocatalytic activity for OER among composite samples in different molar ratios. Moreover, the properties of RuO2IrO2 grown on carbon paper were evaluated by proton exchange membrane water electrolysis single cell. Compared with the micron-particle structure of RuO2IrO2 catalyst on the Ti substrate, the catalyst grown on the carbon paper showed a novel nano dendrite shape and can be used directly as the gas diffusion electrode. Owing to the large surface area of the catalyst, the nano dendrite-shaped RuO2IrO2 catalyst exhibits excellent OER performance in the single cell. Furthermore, a cell voltage of 2.50 V is achieved under 200mA cm2 at 30 oC by using the optimal composition RuO2IrO2 (Ru : Ir=7/3) and the commercial 20% Pt/C as anode and cathode, respectively.