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放射線 治療의 迅速正確을 위한 低溫熔融 遮蔽物의 製作과 應用
秋成實,李道行,朴昌潤 대한방사선방어학회 1979 방사선방어학회지 Vol.4 No.1
高에너지 放射線 治療에 있어서 正常組織의 完全遮蔽를 위하여 5∼8cm 납두께의 不定形 遮蔽벽돌을 製作해야 하는 難點이 있었다. 著者들은 납 30.0%, 주석 11.5% 비스므스 48.5%, 카드미늄 10.0%를 四種 共晶結合시켜 密度가 9.8g/㎤이고 熔融溫度가 68℃인 低熔融 遮蔽物質을 開發하여 이를 Lead Y라고 名命하였다. 製作된 Lead Y Block을 68℃에서 熔融시켜 保護해야할 重要한 臟器의 形態대로 製作된 styrofoam 陰刑에 부어서 遮蔽效果가 큰 遮蔽벽돌을 쉽고 安全하게 製作할 수 있었고 납보다 더 단단하고 再現性이 크며 低廉한 가격으로 購入이 可能하므로 放射線 治療效果에 큰 도움을 줄 수 있었다. For accurate and easily shielding irregular shaped organ, its minimized penumbra region and a low melting point alloy "Lead Y" and synchronizing instrument have been developed. The "Lead Y" is the quaternary eutectic alloy and it is composed of Lead 30.0% Tin 11.5% Bismuth 48.5% Cadmium 10.0% The density of its at 22℃ is 9.8g/㎤ and the melting temperature has 40℃ to 68℃. The thickness of "Lead Y" for perfect shielding of Co-60 gamma ray and LINAC 10MeV x-ray is 6cm and 7cm respectively. The "Lead Y" shielding block is casted directly on the styrofoam from which is cut with hot wire of synchronizer device. The special features and advantages of the Lead Y shielding block could be summarized as follows: 1. The shielding block for radiotherapy is rapidly processed only with boiling water and styrofoam. 2. It is not injure one's health and not danger of a fire, because of not generating of any metals vapor and evil smelling. 3. It is very effective to minimize secondary penumbra for the protection of healthy tissue from unnecessary ionizing radiation regardless of the magnification source to skin distance. 4. The HVL of the Lead Y is 1.2cm for Co-60 gamma ray and it's shielding effect if almost same as the pure lead block. 5. The hardness of Lead Y is 1.5 times higher than lead block. 6. It's reavailability is higher than lead block and then one block of Lead Y is reavailable about 30 to 40 times. 7. It is useful for shielding of x-ray, gamma ray, beta-ray, electron and neutron radiation. 8. The materials for Lead Y are easy to acquire with reasonable price and tractable.
Chu, X.Z.,Cheng, Z.P.,Xiang, X.X.,Xu, J.M.,Zhao, Y.J.,Zhang, W.G.,Lv, J.S.,Zhou, Y.P.,Zhou, L.,Moon, D.K.,Lee, C.H. Pergamon Press ; Elsevier Science Ltd 2014 International journal of hydrogen energy Vol.39 No.9
The separation of a hydrogen isotope mixture on porous materials was studied using equilibrium and breakthrough experiments. The adsorption equilibria of H<SUB>2</SUB> and D<SUB>2</SUB> on SBA-15 with mesopores and molecular sieves 5A, Y, and 10X with micropores were measured at 77 K using the volumetric method. The breakthrough experiments of a H<SUB>2</SUB> and D<SUB>2</SUB> mixture in each adsorbent bed were carried out at various conditions of flow rate and pressure. The equilibrium ratio of D<SUB>2</SUB> to H<SUB>2</SUB> on mesoporous molecular sieves was larger than the ratio on microporous molecular sieves (SBA-15 > 10X > Y > 5A), but the difference among the adsorbents decreased with increases in pressure. On the other hand, the order of breakthrough separation factor showed the opposite result (SBA-15 < 10X < Y < 5A). The breakthrough separation factors for zeolite 10X was approximately equal to the equilibrium ratio of D<SUB>2</SUB> to H<SUB>2</SUB> at the corresponding partial pressures, whereas zeolites 5A and Y showed higher breakthrough separation factors than their equilibrium ratios. In SBA-15, the separation factors from breakthrough results were even smaller than the corresponding equilibrium ratio. In the microporous adsorbent with a limited pore size (zeolite 5A in the study), the diffusion mechanism contributed to the separation of hydrogen isotope gases as one of key factors.
Predictors of survival for patients with cancer after cryptogenic stroke
Shin, Y. W.,Lee, S. T.,Jung, K. H.,Kim, D. Y.,Park, C. K.,Kim, T. M.,Choi, S. H.,Chu, K.,Lee, S. K. M. Nijhoff 2016 Journal of neuro-oncology Vol.128 No.2
<P>Patients with active cancer experience ischemic stroke via cryptogenic mechanisms, with cancer-associated hypercoagulability being considered a major contributor to such strokes. Despite the remarkably shortened survival of these patients, the clinical predictors of survival are poorly understood. We determined the clinical factors including D-dimer levels serving as the predictors of overall survival in these patients. Retrospective study was conducted on cancer patients who visited our hospital for acute ischemic stroke with cryptogenic mechanisms from April 2012 through November 2014. Demographics, clinical characteristics, imaging and laboratory results including coagulation markers were collected, and overall survival was calculated from the patient medical records and a governmental national database. A high D-dimer level was defined as a D-dimer level exceeding the median value from the study population (> 5.50 mu g/ml). A total of 93 patients were identified, with a median survival of 62 days (interquartile range 32-223 days). A high D-dimer level (p = 0.004; hazard ratio [HR] 2.01, 95 % confidence interval [CI] 1.26-3.21), systemic metastases (p = 0.02; HR 2.08, 95 % CI 1.11-3.90), and diabetes mellitus (p = 0.03; HR 1.78, 95 % CI 1.03-3.10) were identified as independent predictors of poor overall survival using multivariate Cox proportional hazard analysis. Most of the patients (87 %) were primarily treated with low-molecular-weight heparin (dalteparin, n = 49; enoxaparin, n = 32). The type of low-molecular-weight heparin had no association with survival. A high D-dimer level, systemic metastases, and diabetes are independent predictors of poor survival in cancer patients with cryptogenic stroke.</P>
Lia, Y.H.,Chu, H.P.,Jiang, Y.N.,Lin, C.Y.,Li, S.H.,Li, K.T.,Weng, G.J.,Cheng, C.C.,Lu, D.J.,Ju, Y.T. Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.5
The Lanyu is a miniature pig breed indigenous to Lanyu Island, Taiwan. It is distantly related to Asian and European pig breeds. It has been inbred to generate two breeds and crossed with Landrace and Duroc to produce two hybrids for laboratory use. Selecting sets of informative genetic markers to track the genetic qualities of laboratory animals and stud stock is an important function of genetic databases. For more than two decades, Lanyu derived breeds of common ancestry and crossbreeds have been used to examine the effectiveness of genetic marker selection and optimal approaches for individual assignment. In this paper, these pigs and the following breeds: Berkshire, Duroc, Landrace and Yorkshire, Meishan and Taoyuan, TLRI Black Pig No. 1, and Kaohsiung Animal Propagation Station Black pig are studied to build a genetic reference database. Nineteen microsatellite markers (loci) provide information on genetic variation and differentiation among studied breeds. High differentiation index ($F_{ST}$) and Cavalli-Sforza chord distances give genetic differentiation among breeds, including Lanyu's inbred populations. Inbreeding values ($F_{IS}$) show that Lanyu and its derived inbred breeds have significant loss of heterozygosity. Individual assignment testing of 352 animals was done with different numbers of microsatellite markers in this study. The testing assigned 99% of the animals successfully into their correct reference populations based on 9 to 14 markers ranking D-scores, allelic number, expected heterozygosity ($H_E$) or $F_{ST}$, respectively. All miss-assigned individuals came from close lineage Lanyu breeds. To improve individual assignment among close lineage breeds, microsatellite markers selected from Lanyu populations with high polymorphic, heterozygosity, $F_{ST}$ and D-scores were used. Only 6 to 8 markers ranking $H_E$, $F_{ST}$ or allelic number were required to obtain 99% assignment accuracy. This result suggests empirical examination of assignment-error rates is required if discernible levels of co-ancestry exist. In the reference group, optimum assignment accuracy was achievable achieved through a combination of different markers by ranking the heterozygosity, $F_{ST}$ and allelic number of close lineage populations.
추정호,이재용,강대성 東亞大學校 附設 環境問題硏究所 2007 硏究報告 Vol.29 No.1
It prevents the problem beforehand such as second infection by an illegal disposal of the waste which is harmful for people, can solve the real problem caused by management and disposal of the waste, using the RFID that is kernel technology of the next generation in this paper. At first, it is possible to prevent managers' impure intention beforehand, using the authentication card that is storing managers' bio-information who is managing the hazard material. Also it suggests efficient solution that can offer better environment that previous managers' working environment, applying the RFID system to every stage, from the first point of the occurrence time of the waste modeled on general material distribution process to the final processing stage.