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Qiong Luo,Zhuoneng Li,Jun Yan,Fan Zhu,Ruo-Jun Xu,Yi-Zhong Cai1 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.4
Lycium barbarum polysaccharides (LBPs) are important functional constituents in red-colored fruits of L. barbarum (Guo Qi Zi, a well-known traditional Chinese medicinal plant commonly known as Goji berry or wolfberry). The influence of LBP on human prostate cancer cells was systematically investigated in vitro and in vivo. The in vitro effects of LBP on two cell lines (PC-3 and DU-145) were examined by using trypan blue exclusion staining, single-cell gel electrophoresis, flow cytometry, terminal dUTP nick-end labeling assay, and immunohistochemical assay (assessment of Bcl-2 and Bax expression). The in vivo effect of LBP on PC-3 cells was assessed in the nude mouse xenograft tumor model. The in vitro results showed that LBP can dose- and time-dependently inhibit the growth of both PC-3 and DU-145 cells. LBP caused the breakage of DNA strands of PC-3 and DU-145 cells; the tail frequency and tail length were significantly higher than that of control cells. LBP also markedly induced PC-3 and DU-145 cell apoptosis, with the highest apoptosis rates at 41.5% and 35.5%, respectively. The ratio of Bcl-2/Bax protein expression following LBP treatments decreased significantly with a dose–effect relationship, which suggested that LBP can regulate the expression of Bcl-2 and Bax to induce apoptosis of PC-3 and DU-145 cells. The in vivo experimental results indicate that LBP might significantly inhibit PC-3 tumor growth in nude mice. Both the tumor volume and weight of the LBP treatment group were significantly lower than those of the control group.
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Xu Hai-Yan,Yang Yi Cai,Li Dong-Cai,Wu Ran Ran,Wang Ai-Guo,Sun Dao-Sheng,Zhang Feng-Jun,오원춘 한국세라믹학회 2023 한국세라믹학회지 Vol.60 No.3
Heavy metal ion pollution of water resources is becoming increasingly serious, and adsorption is one of the most effective strategies for removing heavy metal ions. In the paper, hydrated hydrogen sodium vanadium oxide (HNaV 6O164H2O) fi lm developed for heavy metal ion adsorption was prepared directly via a low-temperature liquid-phase deposition approach. The prepared film shows an interesting porous flower-like morphology and has large spacing ( d = 10.87 Å). The highest adsorption capacity of the obtained HNaV 6O164H2O fi lm for Pb 2+, Cu 2+, Cd 2+ and Mn 2+ is 513 mg/g (2565 mg/m 2), 430 mg/g (2150 mg/m 2), 134 mg/g (875 mg/m 2) and 175 mg/g (670 mg/m 2), respectively. The adsorption percentage of the sample decreased from 92.2 to 86.3% after 4 cycles. The adsorption process follows the Langmuir adsorption isotherm and the pseudo second-order dynamic model, indicating that heavy metal ion adsorption by the fi lm is a single molecular layer chemical adsorption. In combination with various characterizations and comparison tests of samples after adsorption, the adsorption mechanisms include surface electrostatic attraction, complexation, and cation exchange. The results indicate that the fi lm is a potential material to remove heavy metal ions from the aqueous solution.
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Effect of moisture content on dense-phase conveying of pulverized coal at high pressure
Xu Pan,Chen Xiaoping,Liang Cai,Xu Guiling,Liu Daoyin,Zhao Changsui 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.10
In dense-phase pneumatic conveying, the solid moisture content can significantly influence the conveying process, but there are very few studies in the open literature. In this study, the conveying experiments of two pulverized coals with various moisture contents were carried out at a 4MPa high pressure and dense-phase pneumatic conveying facility. Results show that the whole conveying system can be stably and controllably operated under the condition that moisture content below ~8%. With the increase of moisture content up to ~8%, the mass flow rate of 280 μm pulverized coal increases at first and then decreases, while that of 55 μm pulverized coal decreases continuously. The method of solid friction factor correlation is used to investigate pressure drop of the horizontal pipe, and non-dimensional parameters--Fr number, moisture content M and solid loading ratio μ--are investigated. The pressure drop predictions by this correlation are in good agreement with the experimental data. The solid friction factor correlations indicate that the fine coal is more sensitive to M, and μ plays a more important role for the coarse coal.
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Xu, Xiao-Hua,Peng, Xue-Hong,Yu, Ping,Xu, Xiao-Yuan,Cai, Er-Hui,Guo, Pi,Li, Ke Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1
Neoadjuvant chemotherapy for resectable esophageal carcinoma has been a focus of study, but no agreement has been reached on clinical randomized controlled trials and relevant systematic evaluation. The purpose of this study was to perform a meta-analysis on published randomized controlled trials (RCTs) that compared neoadjuvant chemotherapy and surgery with surgery alone for resectable esophageal carcinoma. Medline and manual searches was conducted in PubMed, ASCO (American Society of Clinical Oncology) meeting summary, Embase, the Cochrane Library (up to October 2010), Chinese Biomedical Literature Database, China National Knowledge Infrastructure, VIP Database, Wanfang Database. The selection contents were to identify all published and unpublished RCTs that compared neoadjuvant chemotherapy and surgery with surgery alone for resectable esophageal carcinoma. Sixteen RCTs which included 2,594 patients were selected. The risk ratio (RR) (95% confidence interval [CI]; P value), expressed as neoadjuvant chemotherapy and surgery versus surgery alone (treatment versus control), was 1.02 (0.95, 1.10; P=0.54) for 1-year survival, 1.29 (1.13, 1.47; P=0.0001) for 3-year survival, 1.31 (1.13, 1.51; P=0.0003) for 5-year survival, 1.00 (0.95, 1.04; P= 0.85) for rate of resection and 0.89 (0.64, 1.23; P=0.48) for operative mortality. The results showed that neoadjuvant chemotherapy for resectable esophageal carcinoma can raise the overall survival rate of patients with esophageal carcinoma, but it does not affect treatment-related mortality.
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Yuanbo Xu,Zongyan Cai,Xiaoyan Cai,Kai Ding 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.6
Previous research has shown that minimum entropy deconvolution (MED) is an effective technique for detecting impulse-like signals, such as the bearing fault and gear fault signals. However, some problems still exist in this technique. With the aim of overcoming these limitations, in this paper, an enhanced MED called multipoint optimal minimum entropy deconvolution adjusted (MOMEDA) is proposed. MOMEDA can succeed in detecting multiple impulses. Unfortunately, according to some simulations and real tests in this work, the results of applying this technique to the fault signals directly were grudgingly acceptable but not very satisfactory, especially under a harsh working condition. This means that MOMEDA is a little sensitive to intensive background noise and vibration interference. To overcome this drawback, a novel mode decomposition method, named time-varying filtering for empirical mode decomposition (TVFEMD), is applied to adaptively eliminate background noise and vibration interference prior to using MOMEDA. According to this proposed method, the weak bearing fault features can be identified clearly. The proposed approach is utilized in bearing fault detection of a spur gearbox and the results show its superiority and effectiveness.
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Preparation of porous cordierite ceramic with acid-leached coal gangue
Wang Xu-Dong,Xu Hai-Yan,Zhang Feng-Jun,Li Dong-Cai,Wang Ai-Guo,Sun Dao-Sheng,오원춘 한국세라믹학회 2020 한국세라믹학회지 Vol.57 No.4
The eff ect of impurities in coal gangue on the sintering and properties (porosity and compressive strength) of porous cordierite ceramics has been investigated by adjusting the amount of impurities by controlling the acid–gangue ratio during acid leaching. The sintering behavior and microstructure of the porous ceramics have been characterized via X-ray diff ractometry and scanning electron microscopy. The eff ects of both the acid–gangue ratio and sintering temperature on the porosity and compressive strength have been also investigated. The results indicated that both porosity and compressive strength of the porous cordierite ceramics prepared using acid-leached coal gangue were evidently improved. The content of the impurities in coal gangue was adjusted via acid leaching by controlling the acid–gangue ratio. The appropriate content of impurities in coal gangue facilitated the sintering process and improved the porosity and compressive strength of the obtained porous cordierite ceramics.
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Yujing Xu,Chaoli Wang,Gang Wang,Xuan Cai,Luyan Xu,Chonglin Jing 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.12
When the actuator faults and the control directions are unknown, the difficulty of the asymptotically tracking control of the surface vessel will increase. In this paper, for actuator failures and unknown control directions, a distributed adaptive asymptotically synchronous tracking control law for multiple uncertain underactuated surface vessels (USVs) is proposed, which can achieve network connectivity and good tracking performance in a limited communication range. First, a distributed nonlinear error surface is introduced to achieve synchronous tracking between USVs and maintain the initial connectivity patterns. Second, a conditional inequality is proposed to solve the problems of unknown actuator failures and unknown control directions. Then, combined with the derived technical lemmas and Barbalat’s lemma, the stability of the closed loop system is proved by the Lyapunov method. Finally, a simulation example verifies the theoretical results.
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Ming Cai Xu,Zhao Jun Song,Jin Pan 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.4
The fi re accidents casually happen during operation of ship, which would infl uence the load carrying capacity of stiff ened panel of ship structures due to the thermal load. The present paper aims to understand the infl uence of thermal loads on the collapse behaviour of stiff ened panels under longitudinal compressive load. Considering the heating and cooling down processes, the collapse behaviours of the stiff ened panels under combined in-plane displacement and heat loads representative of fi re accident are simulated in the FE (fi nite element) analysis herein. Firstly, the thermal load is considered to investigate the stress state of the stiff ened panels during heating and cooling processes. It is found that the stiff ened panels would collapse during thermal loads for the structure with large heated zone. After that, the longitudinal compression loads are applied to assess the collapse strength of the stiff ened panels. The parametric studies including diff erent geometrical dimensions and areas of heat zone are performed in detail to quantify the eff ects of heat loads on the collapse behaviours of stiff ened panels. It is found that the expansion could produce biaxial stress state that depends on not only in-plane stiff ness but also collapse modes, and for stiff ened panels with various heated area the cooling down to room temperature induce similar ultimate strength to that without considering heat loads.
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