A Study on the Element of Total Tour Experience from UX Perspective

Zhou Xiong Jin,Young Hwan Pan 대한인간공학회 2016 대한인간공학회 학술대회논문집 Vol.2016 No.06

Objective: In order to design a new service for the traveler, all the cases that without any missing cases must to be considered. In this study, we starting from the traveler point of view and try to make the classification for the type of traveler’s activities that include all cases. Background: Unlike the past, we live in an age of information, and our travel behavior becomes more diverse. Diversification and spread of smart devices and more travel-related services made these images more obviously. According to this rapidly changing form of travel, to give travelers a better travel experience, some research is needed on travel behavior of the traveler’s point of view. Method: Through an analysis of the existing research, discovered the problems and improved the problems on the basis of the actual situation. Conclusion: Through this study, we are able to take a partial approach on design of travel. And allows the missing phenomenon does not occur. Application: The travel behavior models may help to discover new opportunities and insights on travel development.

Acoustic emission characterization of the fracture process in steel fiber reinforced concrete

Xiong Zhou,Yuyou Yang,Xiangqian Li,Guoqing Zhao 사단법인 한국계산역학회 2016 Computers and Concrete, An International Journal Vol.18 No.4

The correlation between the characteristics of acoustic emission signals and the strength parameters of concretes is investigated by combining the acoustic emission (AE) technique and steel fiber reinforced concrete (SFRC). By means of AE detection system, three kinds of steel fibers of varying content were used as reinforcement in concrete and their influence on the fracture process and the acoustic activity was considered in this paper. Analysis of the AE test results revealed that for different steel fiber contents, the role of steel fiber is different. Concave-convex steel fiber has an inhibitory effect on the control of crack expansion. Bow steel fiber has a better effect on the control of crack propagation when the fiber content is lower. The compressive strength of SFRC decrease when bow steel fiber content rises. Ultra-short can prevent early cracks of concrete.

Establishing a Nomogram for Stage IA-IIB Cervical Cancer Patients after Complete Resection

Zhou, Hang,Li, Xiong,Zhang, Yuan,Jia, Yao,Hu, Ting,Yang, Ru,Huang, Ke-Cheng,Chen, Zhi-Lan,Wang, Shao-Shuai,Tang, Fang-Xu,Zhou, Jin,Chen, Yi-Le,Wu, Li,Han, Xiao-Bing,Lin, Zhong-Qiu,Lu, Xiao-Mei,Xing, H Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

Background: This study aimed to establish a nomogram by combining clinicopathologic factors with overall survival of stage IA-IIB cervical cancer patients after complete resection with pelvic lymphadenectomy. Materials and Methods: This nomogram was based on a retrospective study on 1,563 stage IA-IIB cervical cancer patients who underwent complete resection and lymphadenectomy from 2002 to 2008. The nomogram was constructed based on multivariate analysis using Cox proportional hazard regression. The accuracy and discriminative ability of the nomogram were measured by concordance index (C-index) and calibration curve. Results: Multivariate analysis identified lymph node metastasis (LNM), lymph-vascular space invasion (LVSI), stromal invasion, parametrial invasion, tumor diameter and histology as independent prognostic factors associated with cervical cancer survival. These factors were selected for construction of the nomogram. The C-index of the nomogram was 0.71 (95% CI, 0.65 to 0.77), and calibration of the nomogram showed good agreement between the 5-year predicted survival and the actual observation. Conclusions: We developed a nomogram predicting 5-year overall survival of surgically treated stage IA-IIB cervical cancer patients. More comprehensive information that is provided by this nomogram could provide further insight into personalized therapy selection.

Crystallization, Rheology and Foam Morphology of Branched PLA Prepared by Novel Type of Chain Extender

Mi Zhou,Ping Zhou,Ping Xiong,Xin Qian,Haha Zheng 한국고분자학회 2015 Macromolecular Research Vol.23 No.3

Improving the melt strength of polylactide (PLA) is of continuing strategic research highlight, since thisproperty affects the foaming processability. Using a novel type chain extender, namely polystyrene/poly(glycidylmethacrylate) random copolymer, PLA is branched through melt compounding. Comparing to the neat PLA, the newbranched products characterize significantly improved complex viscosity as well as elongational viscosity shownfrom rheological experiments. Furthermore, differential scanning calorimetry analysis (DSC) indicates the branchedstructure could also hinder cold crystallization. Owing to the improved viscous and elastic properties, the foams ofbranched PLA exhibits smaller cell size and higher density, when we use supercritical carbon dioxide (Sc-CO2) asthe physical foaming agent.

구조 관계 중심의 디지인 모델링 언어 시스템

김주웅(Zhou-Xiong Jin),반영환(Young-Hwan Pan) 한국디지털콘텐츠학회 2020 한국디지털콘텐츠학회논문지 Vol.21 No.5

디지털 환경에서의 회전인터렉션 분류체계에 관한 연구

김주웅(Jin, Zhou Xiong),반영환(Pan, Young Hwan) 한국IT서비스학회 2015 한국IT서비스학회 학술대회 논문집 Vol.2015 No.추계

모든 산업 기술들이 그러하듯이 대중화라는 보급단계에 들어서면서 새로운 인터랙션방식이 필요하게 된다. 3D프린터의 보급과 VR기기의 보급을 예상했을 때 점차 많은 편집인터랙션이 적용된 사용자 맞춤형 소프트웨어들이 필요하게 될 것이다. 본 연구에서는 이러한 편집 인터랙션중 가장 사용이 빈번할 것으로 예상되는 회전인터랙션에 주목하여 연구를 진행하였다. 회전의 개념을 현실세계와 디지털환경을 비교하면서 대상을 기준으로 정의를 진행 했고 회전을 실현함에 있어서 필요한 요소들을 도출 하였다. 회전인터랙션의 사례분석을 통하여 디지털 환경에서의 회전 인터랙션 분류 프레임워크를 구성하였다. 본 연구에 서의 분류체계는 인터랙션 디자이너로 하여금 더 좋은 회전경험을 사용자들한테 제공할 수

Identification of Cisplatin-Resistance Associated Genes through Proteomic Analysis of Human Ovarian Cancer Cells and a Cisplatin-resistant Subline

Zhou, Jing,Wei, Yue-Hua,Liao, Mei-Yan,Xiong, Yan,Li, Jie-Lan,Cai, Hong-Bing Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12

Chemoresistance to cancer therapy is a major obstacle to the effective treatment of human cancers with cisplatin (DDP), but the mechanisms of cisplatin-resistance are not clear. In this study, we established a cisplatin-resistant human ovarian cancer cell line (COC1/DDP) and identified differentially expressed proteins related to cisplatin resistance. The proteomic expression profiles in COC1 before and after DDP treatment were examined using 2-dimensional electrophoresis technology. Differentially expressed proteins were identified using matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and high performance liquid chromatography-electrospray tandem MS (NanoUPLC-ESI-MS/MS). 5 protein spots, for cytokeratin 9, keratin 1, deoxyuridine triphosphatase (dUTPase), aarF domain containing kinase 4 (ADCK 4) and cofilin1, were identified to be significantly changed in COC1/DDP compared with its parental cells. The expression of these five proteins was further validated by quantitative PCR and Western blotting, confirming the results of proteomic analysis. Further research on these proteins may help to identify novel resistant biomarkers or reveal the mechanism of cisplatin-resistance in human ovarian cancers.

Effect of Vehicle-Bridge Interaction Vibration on Young Concrete

Xiong Zhang,Ming Zhao,Yong-juan Zhang,Zhou Lei,Yue-ran Zhang 대한토목학회 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.1

The purpose of this investigation was to study the effect of vehicle-bridge interaction vibration on repairing concrete. A newlydeveloped systematic test was used to simulate the vibration and evaluate its effect. The results indicated that both external damageand internal damage were serious when the simulated vibration test was conducted during a special time period. And this special timeperiod was defined as the concrete disturbance sensitive period when the penetration resistance ranged from 3.5 MPa to 28 MPa. Anti-cracking fiber and self-healing admixture improved the vibration resistance of young concrete. When the dosage of anticrackingfiber came to 800 g/m3 by volume of concrete, the 3-day crack area on the concrete surface decreased over 50%. When 9%self-healing admixture was added to the concrete, the ultrasonic pulse velocity of concrete subjected to vibration was higher all thetime than without the admixture added. And the ultrasonic pulse velocity at the age of 28 days reached 95% of the control concretewhich suffered no vibration. Sand percentage and maximum aggregate size were found to significantly influence the vibrationresistance of concrete.

HLA–DPB1 and DPB2 are genetic loci for systemic sclerosis: A genome-wide association study in Koreans with replication in North Americans

Zhou, Xiaodong,Lee, Jong Eun,Arnett, Frank C.,Xiong, Momiao,Park, Min Young,Yoo, Yeon Kyeong,Shin, Eun Soon,Reveille, John D.,Mayes, Maureen D.,Kim, Jin Hyun,Song, Ran,Choi, Ji Yong,Park, Ji Ah,Lee, Y Wiley Subscription Services, Inc., A Wiley Company 2009 Vol.60 No.12

<B>Objective</B><P>To identify systemic sclerosis (SSc) susceptibility loci via a genome-wide association study.</P><B>Methods</B><P>A genome-wide association study was performed in 137 patients with SSc and 564 controls from Korea using the Affymetrix Human SNP Array 5.0. After fine-mapping studies, the results were replicated in 1,107 SSc patients and 2,747 controls from a US Caucasian population.</P><B>Results</B><P>The single-nucleotide polymorphisms (SNPs) (rs3128930, rs7763822, rs7764491, rs3117230, and rs3128965) of HLA–DPB1 and DPB2 on chromosome 6 formed a distinctive peak with log P values for association with SSc susceptibility (P = 8.16 × 10<SUP>−13</SUP>). Subtyping analysis of HLA–DPB1 showed that DPB1*1301 (P = 7.61 × 10<SUP>−8</SUP>) and DPB1*0901 (P = 2.55 × 10<SUP>−5</SUP>) were the subtypes most susceptible to SSc in Korean subjects. In US Caucasians, 2 pairs of SNPs, rs7763822/rs7764491 and rs3117230/rs3128965, showed strong association with SSc patients who had either circulating anti–DNA topoisomerase I (P = 7.58 × 10<SUP>−17</SUP>/4.84 × 10<SUP>−16</SUP>) or anticentromere autoantibodies (P = 1.12 × 10<SUP>−3</SUP>/3.2 × 10<SUP>−5</SUP>), respectively.</P><B>Conclusion</B><P>The results of our genome-wide association study in Korean subjects indicate that the region of HLA–DPB1 and DPB2 contains the loci most susceptible to SSc in a Korean population. The confirmatory studies in US Caucasians indicate that specific SNPs of HLA–DPB1 and/or DPB2 are strongly associated with US Caucasian patients with SSc who are positive for anti–DNA topoisomerase I or anticentromere autoantibodies.</P>

Preliminary conceptual design of a small high-flux multi-purpose LBE cooled fast reactor

Xiong Yangbin,Duan Chengjie,Zeng Qin,Ding Peng,Song Juqing,Zhou Junjie,Xu Jinggang,Yang Jingchen,Li Zhifeng 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.8

The design concept of a Small High-flux Multipurpose LBE(Lead Bismuth Eutectic) cooled Fast Reactor (SHMLFR) was proposed in the paper. The primary cooling system of the reactor is forced circulation, and the fuel element form is arc-plate loaded high enrichment MOX fuel. The core is cylindrical with a flux trap set in the center of the core, which can be used as an irradiation channel. According to the requirements of the core physical design, a series of physical design criteria and constraints were given, and the steady and transient parameters of the reactor were calculated and analyzed. Regarding the thermal and hydraulic phenomena of the reactor, a simplified model was used to conduct a preliminary analysis of the fuel plates at special positions, and the temperature field distribution of the fuel plate with the highest power density under different coolant flow rates was simulated. The results show that the various parameters of SHMLFR meet the requirements and design criteria of the physical design of the core and the thermal design of the reactor. This implies that the conceptual design of SHMLFR is feasible