Encapsulation of Hepatocytes for Bioartificial Liver System

Xing Lin Cuo,Kyung Su Yang,Chong Su Cho,Inn Kyu Kang 한국고분자학회 2001 한국고분자학회 학술대회 연구논문 초록집 Vol.2001 No.10

Recognition and Identification of College Students' Classroom Behaviors through Deep Learning

Xing Su,Wei Wang 대한전자공학회 2023 IEIE Transactions on Smart Processing & Computing Vol.12 No.5

Recognizing and managing college students' classroom behavior in a timely manner is of great help in improving teaching quality and strengthening classroom management. This paper builds a model based on the You Only Look Once Version 5 Small (YOLO v5s) algorithm using deep learning to detect and identify college students' classroom behaviors. The LabelImg annotation tool was used to process the dataset images, and the labeled dataset was the input for the object detection model to recognize college students' classroom behaviors. Although the precision, recall, mean average precision (mAP), and detection speed of the YOLO v5s model were slightly lower with large classroom densities, compared to medium classroom densities, the difference was negligible. At the same time, the mAP values of the proposed model under three different intersection-over-union thresholds were higher than the single shot multibox detector and region-based convolutional neural network models, reaching 95.8, 94.3, and 92.9. This paper proves that YOLO v5s can effectively and accurately recognize classroom behavior in real time.

Composite action of concrete-filled double circular steel tubular stub columns

Liping Wang,Xing-xing Cao,Fa-Xing Ding,Liang Luo,Yi Sun,Xue-mei Liu,Hui-lin Su 국제구조공학회 2018 Steel and Composite Structures, An International J Vol.29 No.1

This paper presents a combined numerical, experimental, and theoretical study on the behavior of the concrete-filled double circular steel tubular (CFDT) stub columns under axial compressive loading. Four groups of stub column specimens were tested in this study to find out the effects of the concrete strength, steel ratio and diameter ratio on the mechanical behavior of CFDT stub columns. Nonlinear finite element (FE) models were also established to study the stresses of different components in the CFDT stub columns. The change of axial and transverse stresses in the internal and external steel tubes, as well as the change of axial stress in the concrete sandwich and concrete core, respectively, was thoroughly investigated for different CFDT stub columns with the same steel ratio. The influence of inner-to-outer diameter ratio and steel ratio on the ultimate bearing capacity of CFDT stub columns was identified, and a reasonable section configuration with proper inner-to-outer diameter ratio and steel ratio was proposed. Furthermore, a practical formula for predicting the ultimate bearing capacity was proposed based on the ultimate equilibrium principle. The predicted results showed satisfactory agreement with both experimental and numerical results, indicating that the proposed formula is applicable for design purposes.

QTL analyses for 8 agronomic characters in two populations of rice derived from wide compatibility line

Jeonghwan Seo,Huang Xing,Su Jang,Sunghan Kim,Hee-Jong Koh 한국육종학회 2013 한국육종학회 심포지엄 Vol.2013 No.07

Hybrid sterility is a critical barrier of inter-subspecific crosses in rice. However, hybrid sterility can be overcome by wide compatibility variety. The HWC-line of rice had slender grain shape, tall culm length, wide compatibility with both indica and japonica cultivars. For QTL analysis of HWC-line, two F2 populations were derived from the crosses between the HWC-line and each of two Korean variety, Dasan (Korean Tongil-type cultivar) and Hwacheong (temperate japonica cultivar). In the cross between HWC-line/Dasan (HD), 93 STS markers and 13 SSR markers were mapped on 12 chromosomes. In the population from HWC-line/Hwacheong (HH) cross, 28 STS markers, 29 SSR markers and 1 FNP marker were mapped on 11 chromosomes. Eight agronomic characters were evaluated for QTL analysis in two F2 populations and parents. The F2 population from HD cross revealed 21 M-QTLs and 3 E-QTL for culm length, spikelet per panicle, spikelet fertility, grain length, grain width, grain shape and 100 grains weight. 8 QTLs of culm length, grain length, grain width and grain shape were newly detected in this study. In the F2 population from HH cross, 17 M-QTLs were detected for culm length, panicle length, spikelet fertility, grain length, grain width, grain shape and 100 grains weight. 6 QTLs of culm length, grain length, grain width and grain shape were newly found in this study. These QTLs will be able to provide basic information on putative functional genes related with agronomic characters and promote breeding new rice cultivar. HWC-line could be used as bridge for inter-subspecies crosses and in hybrid breeding.

Effect of Low-fat Diet on Breast Cancer Survival: a Meta-analysis

Xing, Mei-Yuan,Xu, Su-Zhen,Shen, Peng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.3

Background: Even though many studies have examined the possible effect of low-fat diet on breast cancer survival, the relationship remains unclear. Objectives: To summarize the current evidence about the effect of post-diagnostic low-fat diet on recurrence and all-cause mortality of breast cancer. Methods: We conducted a search of Pubmed, Embase, Web of Science, and Cochrane Library and as a result two randomized controlled trials (RCT) and one large multi-center prospective cohort study with 9,966 breast cancer patients were included in this report. Results: Post-diagnostic low-fat diet reduced risk of recurrence of breast cancer by 23% (HR=0.77, 95%CI 0.63 to 0.94, P=0.009) and all cause mortality of breast cancer by 17% (HR=0.83, 95%CI 0.69 to 1.00, P=0.05). Conclusions: This meta-analysis suggested the post-diagnostic low-fat diet can improve breast cancer survival by reducing risk of recurrence. However, more trials of the relationship between low-fat diet and allcause mortality of breast cancer are still needed.

On the hydraulic axial thrust of Francis hydro-turbine

Xing-Ying Ji,Xiao-Bin Li,Wen-Tao Su,Xu Lai,Tian-Xiao Zhao 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.5

We present a new method for the computation of hydraulic axial thrust of Francis hydro-turbine. This approach combines the computation of axial thrust on the crown, band and blade by using the numerical simulation and calculation of the pressure distribution outside the crown and band based on the theory of fluid mechanics. The axial thrusts are calculated for different flow conditions with various suction head and flow rate. The calculated results are consistent with that of experimental test on the prototype hydro-turbine, and this combination is proven to be an effective way to assess the magnitude of hydraulic axial thrust for hydro-turbine. Also, the suction head of the turbine is shown to have significant influence on the hydraulic axial thrust.

Molecular characterization of a delta class glutathione S-transferase gene from the black cutworm Agrotis ipsilon

Su Liu,Ye Cao,Yu-Xing Zhang,Yue-Min Pan,Shi-Guang Li 한국응용곤충학회 2017 Journal of Asia-Pacific Entomology Vol.20 No.4

In insects, glutathione S-transferases (GSTs) play essential roles in the detoxification of xenobiotic toxins and elimination of oxidative stress induced by toxic compounds. In the present study, a delta class GST gene (AiGSTd) was identified and characterized in the black cutworm, Agrotis ipsilon (Lepidoptera: Noctuidae). The deduced protein sequence of AiGSTd contained highly conserved features of GST enzymes and shared high identities with its orthologs from other lepidopteran species. Recombinant AiGSTD protein was expressed in Escherichia coli and purified. The protein displayed the GSH-dependent conjugating activity toward the substrate 1-chloro-2,4-dinitrobenzene (CDNB). Moreover, AiGSTD had the ability to protect DNA from oxidative damage, and the E. coli cells overexpressing AiGSTD showed long-term resistance to oxidative stress. The AiGSTd transcripts were most abundant in the larval midgut. Exposure to chlorpyrifos and lambda-cyhalothrin increased lipid peroxidation in larvae and significantly upregulated AiGSTd expression levels. This study is the first report of molecular characterization of a GST in A. ipsilon, and the present study suggest that AiGSTD might be involved in protecting against the oxidative stress induced by insecticides.

A carbon-coated Li3V2(PO4)3 cathode material with an enhanced high-rate capability and long lifespan for lithium-ion batteries

Su, Jing,Wu, Xing-Long,Lee, Jong-Sook,Kim, Jaekook,Guo, Yu-Guo The Royal Society of Chemistry 2013 Journal of materials chemistry. A, Materials for e Vol.1 No.7

Applying the OMOP Common Data Model to Facilitate Benefit-Risk Assessments of Medicinal Products Using Real-World Data from Singapore and South Korea

Hui Xing Tan,Desmond Chun Hwee Teo,이동윤,김청수,Jing Wei Neo,Cynthia Sung,Haroun Chahed,Pei San Ang,Doreen Su Yin Tan,박래웅,Sreemanee Raaj Dorajoo 대한의료정보학회 2022 Healthcare Informatics Research Vol.28 No.2

Objectives: The aim of this study was to characterize the benefits of converting Electronic Medical Records (EMRs) to acommon data model (CDM) and to assess the potential of CDM-converted data to rapidly generate insights for benefitriskassessments in post-market regulatory evaluation and decisions. Methods: EMRs from January 2013 to December 2016were mapped onto the Observational Medical Outcomes Partnership-CDM (OMOP-CDM) schema. Vocabulary mappingswere applied to convert source data values into OMOP-CDM-endorsed terminologies. Existing analytic codes used in a priorOMOP-CDM drug utilization study were modified to conduct an illustrative analysis of oral anticoagulants used for atrialfibrillation in Singapore and South Korea, resembling a typical benefit-risk assessment. A novel visualization is proposed torepresent the comparative effectiveness, safety and utilization of the drugs. Results: Over 90% of records were mapped ontothe OMOP-CDM. The CDM data structures and analytic code templates simplified the querying of data for the analysis. Intotal, 2,419 patients from Singapore and South Korea fulfilled the study criteria, the majority of whom were warfarin users. After 3 months of follow-up, differences in cumulative incidence of bleeding and thromboembolic events were observable viathe proposed visualization, surfacing insights as to the agent of preference in a given clinical setting, which may meaningfullyinform regulatory decision-making. Conclusions: While the structure of the OMOP-CDM and its accessory tools facilitatereal-world data analysis, extending them to fulfil regulatory analytic purposes in the post-market setting, such as benefit-riskassessments, may require layering on additional analytic tools and visualization techniques.

Identification of putative carboxylesterase and aldehyde oxidase genes from the antennae of the rice leaffolder, Cnaphalocrocis medinalis (Lepidoptera: Pyralidae)

Yu-Xing Zhang,Wen-Long Wang,Mao-Ye Li,Shi-Guang Li,Su Liu 한국응용곤충학회 2017 Journal of Asia-Pacific Entomology Vol.20 No.3

In insects, odorant-degrading enzymes (ODEs) play essential roles in the degradation of volatile odorants and maintenance of olfactory sensitivity. ODEs include several enzyme families with detoxification functions, such as carboxylesterases (CXEs) and aldehyde oxidases (AOXs). The rice leaffolder, Cnaphalocrocis medinalis (Lepidoptera: Pyralidae), is a serious rice insect pest in Asia. In this study, 18 putative CXE genes and four AOX genes were identified from the antennae of C. medinalis by retrieving a previously released transcriptome dataset. BLASTX searching and phylogenetic analyses showed that these genes are closely related to their respective orthologs in other lepidopteran species. Expression patterns of these genes were determined by reverse transcription- quantitative PCR (RT-qPCR). Four candidate genes, including three CmedCXEs (CmedCXE17, CmedCXE20 and CmedCXE24) and one CmedAOX (CmedAOX2) were antenna-enriched and considered potentially involved in odorant degradation. Our findings provide a comprehensive sequence resource and expression profiles of CXE and AOX genes in C. medinalis antennae, which may facilitate further studies of the odorant degradation mechanisms in this insect species.