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Deterministic Secure Quantum Communication Without Maximally Entangled States
Xi-Han Li,Fu-Guo Deng,Chun-Yan Li,Hong-Yu Zhou,Ping Zhou,Yu-Jie Liang 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.4
Two deterministic secure quantum communication schemes are proposed, one based on pure entangled states and the other on d-dimensional single-photon states. In these two schemes, only single-photon measurements are required for the two authorized users, which makes the schemes more convenient than others in practical applications. Although each qubit can be read out after a transmission of additional classical bit, it is unnecessary for the users to transmit qubits double the distance between the sender and the receiver, which will increase their bit rate and their security. The parties use decoy photons to check eavesdropping efficiently. The obvious advantage in the first scheme is that the pure entangled source is feasible with present techniques.
HOCl Oxidation-modified CT26 Cell Vaccine Inhibits Colon Tumor Growth in a Mouse Model
Zhou, Rui,Huang, Wen-Jun,Ma, Cong,Zhou, Yan,Yao, Yu-Qin,Wang, Yu-Xi,Gou, Lan-Tu,Yi, Chen,Yang, Jin-Liang Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8
Despite progress in elucidating mechanisms associated with colorectal cancer and improvement of treatment methods, it remains a frequent cause of death worldwide. New and more effective therapies are therefore urgently needed. Recent studies have shown that immunogenicity of whole ovarian tumor cells and subsequent T cell response were potentiated by oxidation modification with hypochlorous acid (HOCl) in vitro and ex vivo. These results prompted us to investigate the protective antitumor response with an HOCl treated CT26 colorectal cancer cell vaccine in an in vivo mouse model. Administration of HOCl modified vaccine triggered robust antitumor immunity to autologous tumor cells in mice and prolonged survival period significantly. In addition, increased necrosis and apoptosis were found in tumor tissue from the oxidation group. Interestingly, ELISPOT assays showed that specific T cell responses were not elicited in response to the immunizing cellular antigen, in contrast to raising sera antibody titer and antibody binding activity shown by ELISA assay and flow cytometry. Further evaluation of the mechanisms underlying HOCl modified vaccine mediated humoral immunity highlighted the role of antibody-dependent cell-mediated cytotoxicity. These results combined with previous studies suggest that HOCl oxidation modified whole cell vaccine has wide applicability as a cancer vaccine because it can target both T cell- and B cell-specific responses. It may thus represent a promising approach for the immunotherapy of colorectal cancer.
Wang, Xian-Yu,Wang, Songhu,Hinse, Tobias C.,Li, Kai,Wang, Yong-Hao,Laughlin, Gregory,Liu, Hui-Gen,Zhang, Hui,Wu, Zhen-Yu,Zhou, Xu,Zhou, Ji-Lin,Hu, Shao-Ming,Wu, Dong-Hong,Peng, Xi-Yan,Chen, Yuan-Yuan Astronomical Society of the Pacific 2018 Publications of the Astronomical Society of the Pa Vol.130 No.988
서비스디자인에 기초한 외국 유학생의 대학 생활 실태 사례 연구 -"K"대학을 중심으로-
신계옥(주저자) ( Qing Zhou ),주경(공동저자) ( Qing Zhou ),주우(공동저자) ( Yu Zhou ),녕미형 ( Mei Ying Ning ),무문일 ( Wen Yi Wu ),서신희 ( Chen Xi Xu ) 커뮤니케이션디자인학회 2015 커뮤니케이션 디자인학연구 Vol.52 No.-
본 연구는 서비스 디자인 관점에서 ``K``대학에서 공부하고 있는 외국인 34명의 유학생을 대상으로 서비스디자인의 사고방식과 도구 활용 및 프로세스와 방법을 적용하여 대학 생활에서의 불편 요인을 파악하고 문제점을 도출하고자 하였다. 그 결과 대학 생활에서의 유형, 무형의 불편 요인의 실체를 파악할 수 있었다. 즉, 식당 및 기숙사, 강의실에서의 문제들과 교내외 교통 및 이동 수단, 외국인들을 위한 안내책자의 부재로 인한 대학생활의 불편한 사항들이 파악되었다. 이러한 문제들이 개선되고 해결되어야 ``K`` 대학에서 일정기간동안 유학하는 외국 유학생들이 불편한 점이 없이 교육적 목적을 달성할 수 있으며, 이후에도 미래의 친한인재로 교류의 기틀이 되어 바람직한 미래의 가치가 창출될 수 있다고 생각한다. This paper, from the point of view of the design of services, take advantage of the service design concepts and tools to target foreigners 34 international students who are studying at the University of "K", to apply the process and methods of college life grasps the inconvenience factors in the medium, it is attempted to derive a problem. As a result, it was able to grasp the tangible, intangible of failure factor entities in college life. In other words, transportation and means of transportation outside the school, inconveniences of college life by the absence of a brochure for foreigners and restaurant, dormitory, is a problem in the classroom has been grasped. Basis of these issues are improved at the University of "K" should be resolved foreign students is inconvenient point without having a certain period of time studying abroad, it is possible to achieve the educational purposes, after also exchanges in the future of the close human resources I think that the value of the desired future is created to become.
Yu Zhang,Songmin Zhou,Xun Li,Xi Wang,Liqi Zhu,Chun Lin 대한전자공학회 2022 Journal of semiconductor technology and science Vol.22 No.2
Unstable pixels directly affect the imaging quality of the long-wavelength infrared (LWIR) mercury cadmium telluride (HgCdTe, MCT) focal-plane-array (FPA) detector. This study investigates the unstable pixels of LWIR HgCdTe linear arrays with different passivation. According to the different fluctuation characteristics, the unstable pixels are classified into four types: trend-clear type (including the rising and declining pixels), fluctuating type, comb type, and telegraph type. The number of unstable pixels under different bias voltage is counted, which indicates that when the bias voltage is large enough, the number of unstable pixels can increase sharply. By comparing the characteristics of the unstable pixels of two linear arrays with different passivation, we find that the unstable pixels are sensitive to the surface passivation. In addition, the dark currents of unstable pixels and that of normal pixels are compared, inferring that there is no apparent connection between the cause of the instability of the pixels and that of the dark current.
Dynamic response analysis of generally damped linear system with repeated eigenvalues
Yu, Rui-Fang,Zhou, Xi-Yuan,Yuan, Mei-Qiao Techno-Press 2012 Structural Engineering and Mechanics, An Int'l Jou Vol.42 No.4
For generally damped linear systems with repeated eigenvalues and defective eigenvectors, this study provides a decomposition method based on residue matrix, which is suitable for engineering applications. Based on this method, a hybrid approach is presented, incorporating the merits of the modal superposition method and the residue matrix decomposition method, which does not need to consider the defective characteristics of the eigenvectors corresponding to repeated eigenvalues. The method derived in this study has clear physical concepts and is easily to be understood and mastered by engineering designers. Furthermore, this study analyzes the applicability of step-by-step methods, including the Newmark beta and Runge-Kutta methods for dynamic response calculation of defective systems. Finally, the implementation procedure of the proposed hybrid approach is illustrated by analyzing numerical examples, and the correctness and the effectiveness of the formula are judged by comparing the results obtained from the different methods.
Azo-based small molecular hypoxia responsive theranostic for tumor-specific imaging and therapy
Zhou, Ying,Maiti, Mrinmoy,Sharma, Amit,Won, Miae,Yu, Le,Miao, Lan Xi,Shin, Jinwoo,Podder, Arup,Bobba, Kondapa Naidu,Han, Jiyou,Bhuniya, Sankarprasad,Kim, Jong Seung Elsevier 2018 Journal of controlled release Vol.288 No.-
<P><B>Abstract</B></P> <P>We report herein, an azo-derivative (<B>AzP1</B>) of FDA approved antineoplastic drug SN-38 (irinotecan analogue) as a theranostic agent with a potential for both tumor hypoxia-specific activation and therapy. The theranostic <B>AzP1</B> was found to be stable within a biologically relevant pH scale and was chemically inert towards other competitive biological analytes. However, upon treatment with rat-liver microsomes, <B>AzP1</B> showed a self-calibrated fluorescence enhancement at λ<SUB>em</SUB> = 560 nm. The cytotoxicity profile of <B>AzP1</B> was tested in various cancer lines. Under hypoxic conditions, prodrug <B>AzP1</B> exhibited activation to release the parent drug (SN-38) and enhanced cytotoxicity in cancer cells with concomitant fluorescence enhancement at 560 nm, which served to monitor both the drug activation and tracing purposes. The therapeutic potential of <B>AzP1</B> for both tumor-specific activation and suppression of tumor weights was validated in xenograft mouse model. Collectively, the synthetic ease and hypoxia-sensitive activation along with promising therapeutic properties highlight the potential of theranostic <B>AzPI</B> in future cancer treatment programs.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Effects of the Hippo Signaling Pathway in Human Gastric Cancer
Zhou, Guang-Xi,Li, Xiao-Yu,Zhang, Qi,Zhao, Kun,Zhang, Cui-Ping,Xue, Chang-Hu,Yang, Kun,Tian, Zi-Bin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.9
Background/Aim: The Hippo signaling pathway is a newly discovered and conserved signaling cascade, which regulates organ size control by governing cell proliferation and apoptosis. This study aimed to investigate its effects in human gastric cancer. Methods: Tumor tissues (n=60), adjacent non-tumor tissues (n=60) and normal tissues (n=60) were obtained from the same patients with primary gastric cancer (GC). In addition, 70 samples of chronic atrophic gastritis (CAG) tissues were obtained from patients with intestinal metaplasia (IM) by endoscopic biopsy. Hippo signaling molecules, including Mst1, Lats1, YAP1, TAZ, TEAD1, Oct4 and CDX2, were determined by quantitative polymerase chain reaction (qPCR). Protein expression of Mst1, Lats1, YAP1, TEAD1 and CDX2 was assessed by immunohistochemistry and Western blotting. Results: Mst1, Lats1 and Oct4 mRNA expression showed an increasing tendency from GC tissues to normal gastric tissues, while the mRNA expression of YAP1, TAZ and TEAD1 was up-regulated (all P<0.01). Mst1 and Lats1 protein expression presented a similar trend with their mRNA expression. In addition, YAP1 and TEAD1 protein expression in GC was significantly higher than in the other groups (all P<0.01). CDX2 mRNA and protein expression in the CAG group were higher than in the other groups (all P<0.01). In GC, mRNA expression of Mst1, Lats1, Oct4, YAP1, TAZ, TEAD1 and CDX2 had a close correlation with lymphatic metastasis and tumor TNM stage (all P<0.01). Furthermore, protein expression of Mst1, Lats1, YAP1, TAZ, TEAD1 and CDX2 had a close correlation between each other (P<0.05). Conclusion: The Hippo signaling pathway is involved in the development, progression and metastasis of human gastric cancer. Therefore, manipulation of Hippo signaling molecules may be a potential therapeutic strategy for gastric cancer.
Reasoning and fuzzy comprehensive assessment methods based CAD system for boiler intelligent design
Yue-xi Yu,Hong-kai Liao,Yi Zhou,Wei Zhong 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.3
Boilers are key industrial equipment in the field of modern manufacturing. In this study, rule-based reasoning (RBR) and case-basedreasoning (CBR) are applied into the boiler intelligent design. RBR is adopted to perform like a “sieve” for the acquisition of candidatestructure modules. Then, fuzzy comprehensive assessment method is used to select an optimal structure module among the candidates. The optimal structure module is subjected to the CBR process, which includes modification and case retention. It is a minor adjustmentprocess that needs a great amount of prior knowledge. The case retention process gives the system a self-enrich function, which will improvethe design ability of the system with continuous use of the system. A case study is presented to validate the correctness and efficiencyof proposed method.