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Xiaojuan Yang,Qing-Ping Wu,Ju-Mei Zhang,Weipeng Guo,Shuping Mo,Sheng-Rong Liu 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.4
This study aimed to classify a collection of Enterobacter sakazakii (E. sakazakii) strainspreviously identified from powdered infant formula (PIF) to species level by recN gene sequencing andbiochemical testing to determine the distribution of Cronobacter species in China and investigate thestrain diversity by cellular fatty acid (CFA) analysis. Of 24 E. sakazakii isolates, 23 were identified as C. sakazakii and one was C. malonaticus. The 23 C. sakazakii isolates showed the same CFA profiles. TheC. malonaticus isolate was discriminated from the C. sakazakii isolates by the significant difference inthe amounts of C12:0, C14:0, and C17:0 cyclo acids. These results showed that C. sakazakii and C. malonaticuswere the common Cronobacter species distributed in PIF in China and that the isolates of the twospecies exhibited different CFA profiles. These findings are of value for epidemiological investigationsand provide an alternative method for confirming various Cronobacter spp.
Wu, Shuping,Dai, Xiangzi,Shilong, Fangdi,Zhu, Maiyong,Shen, Xiaojuan,Zhang, Kan,Li, Songjun 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.1
Coordination compounds play an important role in the life process, and have been widely used in food, cosmetics and pharmaceutical industry. Herein, we have developed a novel kind of glucosamine-zinc(II) complex (GlcN-ZC) for food additive using non-enzymatic browning reaction. The GlcN-ZC was characterized by FTIR and XRD. Moreover, UV absorbance changes, browning intensity, fluorescence changes, antioxidant activity and antimicrobial assessment of GlcN-ZC were also evaluated. Results showed the GlcN-ZC intermediate compounds were accumulated in non-enzymatic browning while prolonging heating time and melanoidins were produced in the final stage. The fluorescence changes confirmed that fluorophores were formed during the non-enzymatic reaction and fluorescence intensity reached a maximun at 60 min. The highest radical scavenging activity of GlcN-ZC formed after 180 min of heating was 79.2%. Furthermore, GlcN-ZC exhibited excellent antibacterial activity against E. coli and S. aureus. Therefore, GlcN-ZC can be used as a novel promising additive in the food industry.
Shuping Wu,Xiangzi Dai,Fangdi Shilong,Maiyong Zhu,Xiaojuan Shen,Kan Zhang,Songjun Li 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.1
Coordination compounds play an important role in the life process, and have been widely used in food, cosmetics and pharmaceutical industry. Herein, we have developed a novel kind of glucosamine-zinc(II) complex (GlcN-ZC) for food additive using non-enzymatic browning reaction. The GlcN-ZC was characterized by FTIR and XRD. Moreover, UV absorbance changes, browning intensity, fluorescence changes, antioxidant activity and antimicrobial assessment of GlcN-ZC were also evaluated. Results showed the GlcN-ZC intermediate compounds were accumulated in non-enzymatic browning while prolonging heating time and melanoidins were produced in the final stage. The fluorescence changes confirmed that fluorophores were formed during the non-enzymatic reaction and fluorescence intensity reached a maximun at 60 min. The highest radical scavenging activity of GlcN-ZC formed after 180 min of heating was 79.2%. Furthermore, GlcN-ZC exhibited excellent antibacterial activity against E. coli and S. aureus. Therefore, GlcN-ZC can be used as a novel promising additive in the food industry.
Xiaoning Wu,Xiaoqian Xu,Jialing Zhou,Yameng Sun,Huiguo Ding,Wen Xie,Guofeng Chen,Anlin Ma,Hongxin Piao,Bingqiong Wang,Shuyan Chen,Tongtong Meng,Xiaojuan Ou,Hwai-I Yang,Jidong Jia,Yuanyuan Kong,Hong Yo 대한간학회 2023 Clinical and Molecular Hepatology(대한간학회지) Vol.29 No.3
Background/Aims: Existing hepatocellular carcinoma (HCC) prediction models are derived mainly from pretreatment or early on-treatment parameters. We reassessed the dynamic changes in the performance of 17 HCC models in patients with chronic hepatitis B (CHB) during long-term antiviral therapy (AVT). Methods: Among 987 CHB patients administered long-term entecavir therapy, 660 patients had 8 years of follow-up data. Model scores were calculated using on-treatment values at 2.5, 3, 3.5, 4, 4.5, and 5 years of AVT to predict threeyear HCC occurrence. Model performance was assessed with the area under the receiver operating curve (AUROC). The original model cutoffs to distinguish different levels of HCC risk were evaluated by the log-rank test. Results: The AUROCs of the 17 HCC models varied from 0.51 to 0.78 when using on-treatment scores from years 2.5 to 5. Models with a cirrhosis variable showed numerically higher AUROCs (pooled at 0.65–0.73 for treated, untreated, or mixed treatment models) than models without (treated or mixed models: 0.61–0.68; untreated models: 0.51–0.59). Stratification into low, intermediate, and high-risk levels using the original cutoff values could no longer reflect the true HCC incidence using scores after 3.5 years of AVT for models without cirrhosis and after 4 years of AVT for models with cirrhosis. Conclusions: The performance of existing HCC prediction models, especially models without the cirrhosis variable, decreased in CHB patients on long-term AVT. The optimization of existing models or the development of novel models for better HCC prediction during long-term AVT is warranted.
Optimizing opportunistic preventive maintenance strategy for multi-unit system of CNC lathe
Yue Wu,Zhaojun Yang,Jili Wang,Xiaojuan Chen,Wei Hu 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.1
Due to the many components in the multi-unit system (i.e., CNC machine tools), the existing preventive maintenance (PM) strategies conducting independent PM for every component are time-consuming and waste unnecessary maintenance and downtime costs. Hence, this paper introduces the idea of opportunistic maintenance into the PM and proposes an opportunistic imperfect PM approach, which is a more realistic PM policy for a multi-unit system. In this approach, the effect of PM is assumed to be imperfect to correct the failure rate of each unit. According to the corrected failure rate function, the imperfect PM strategy of a single unit is optimized by minimizing the proposed unit maintenance cost rate under the limitation of minimum reliability. Then, these independent imperfect PM strategies for units are rescheduled by the proposed opportunistic PM strategy under the condition of judging the reliability OM threshold of units. We further optimize the opportunistic PM strategy by minimizing the total maintenance cost. Finally, the advantage of our approach is verified by the case study of 18 CNC lathes.
Yang, Xiaojuan,Wu, Qingping,Zhang, Jumei,Guo, Weipeng,Mo, Shuping,Liu, Shengrong 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.4
This study aimed to classify a collection of Enterobacter sakazakii (E. sakazakii) strains previously identified from powdered infant formula (PIF) to species level by recN gene sequencing and biochemical testing to determine the distribution of Cronobacter species in China and investigate the strain diversity by cellular fatty acid (CFA) analysis. Of 24 E. sakazakii isolates, 23 were identified as C. sakazakii and one was C. malonaticus. The 23 C. sakazakii isolates showed the same CFA profiles. The C. malonaticus isolate was discriminated from the C. sakazakii isolates by the significant difference in the amounts of $C_{12:0}$, $C_{14:0}$, and $C_{17:0\;cyclo}$ acids. These results showed that C. sakazakii and C. malonaticus were the common Cronobacter species distributed in PIF in China and that the isolates of the two species exhibited different CFA profiles. These findings are of value for epidemiological investigations and provide an alternative method for confirming various Cronobacter spp.
Guizhong Xu,Xiaojuan Yu,Fahong Wu,Yong Yin 대한토목학회 2017 KSCE JOURNAL OF CIVIL ENGINEERING Vol.21 No.4
It is suggested to use wheat straw as both vertical and horizontal drainage materials when using vacuum consolidation method to process dredged slurry in this paper. To verify the feasibility of this proposal, compression and hydrulic conductivity test on wheat straw and vacuum consolidation tests on slurry using wheat straw as drainage materials were conducted. The results show that the compression process of wheat straw is composed of instantaneous settlement and creep. The density of wheat straw changes from 20 kg/m3 to 200 kg/m3 as vertical stress varies from 5 kPa to 100 kPa. The creep rate increases to maximum when vertical stress reaches 60 kPa and then decreases with as vertical stress further increases. The hydrulic conductivity coefficient of wheat straw is changed between 104 cm/s and 101 cm/s, which decreases linearly as density increases in semi-logarithmic coordinates (hydraulic conductivity in log scale). In vacuum consolidation tests, the settlement, water content, and undrained shear strength of slurry proceeded by vacuum consolidation with wheat straw as drainage materials are similar to those obtained by using PVD and sand as drainage materials. All the results obtained by this paper show that it is feasibility to use wheat straw as vertical and horizontal drainage materials in vacuum consolidation.
Li Xiying,Li Xiaojuan,Wang Xian,Yin Xuan,Li Shanshan,Wu Junyi,Ren Xiumei,Zhang Wei,Mi Yiqun,Xu Shifen 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.3
Background: We conducted this randomized controlled trial (RCT) to evaluate the effectiveness and safety of moxibustion at Sanyinjiao (SP6) acupoint for treatment of negative mood and sleep quality in healthcare workers during the 2019 coronavirus disease (COVID-19). Methods: A total of 180 participants were divided in a 1:1 ratio into two groups, the treatment group (for moxibustion) and the control group (for no treatment). The treatment group had a 30-minute moxibustion therapy once a day for two weeks, followed by a two-week follow-up. The Hamilton Anxiety Scale (HAMA) was used to assess the degree of the participants' anxiety, and the Patient Health Questionnaire-9 (PHQ-9) was utilized to examine their depressed condition. The Maslach Burnout Inventory-General Survey (MBI-GS) was used to measure the level of burnout among healthcare workers. To determine the severity of insomnia, the Sleep Dysfunction Rating Scale (SDRS) was utilized. At baseline, week 2, and week 4, all scales were evaluated. Results: Compared to the control group, The treatment group improved more significantly in the HAMA at week 2 (MD = -19.01, 95% CI: -21.89 to -16.14; P<0.001) and at week 4 follow-up visits (MD = -8.96, 95% CI: -11.19 to -6.73; P<0.001). A subgroup study of HAMA scores revealed that position and education had significant impact on treatment effectiveness. During the 2-week intervention period, the treatment group showed more significant improvements in depressive symptoms measured by PHQ-9 (13.00±2.41 vs. 15.60±3.65; P<0.001), work burnout symptoms measured by MBI-GS (MD = -11.88, 95% CI, -15.73 to -8.03; P<0.001), and insomnia symptoms measured by SDRS (MD = -2.45, 95% CI, -4.24 to -0.66; P<0.01). There were no significant adverse effects reported. Conclusion: Moxibustion at SP6 may be an effective treatment to improve anxiety, depression, sleep quality, and quality of life for healthcare workers during COVID-19.