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Jeong, Seungwon,Lee, Ye-Ryoung,Choi, Wonjun,Kang, Sungsam,Hong, Jin Hee,Park, Jin-Sung,Lim, Yong-Sik,Park, Hong-Gyu,Choi, Wonshik Nature Publishing Group UK 2018 Nature photonics Vol.12 No.5
<P>The efficient delivery of light energy is a prerequisite for the non-invasive imaging and stimulating of target objects embedded deep within a scattering medium. However, the injected waves experience random diffusion by multiple light scattering, and only a small fraction reaches the target object. Here, we present a method to counteract wave diffusion and to focus multiple-scattered waves at the deeply embedded target. To realize this, we experimentally inject light into the reflection eigenchannels of a specific flight time to preferably enhance the intensity of those multiple-scattered waves that have interacted with the target object. For targets that are too deep to be visible by optical imaging, we demonstrate a more than tenfold enhancement in light energy delivery in comparison with ordinary wave diffusion cases. This work will lay a foundation to enhance the working depth of imaging, sensing and light stimulation.</P>
Polyhedral Au Nanocrystals Exclusively Bound by {110} Facets: The Rhombic Dodecahedron
Jeong, Gyoung Hwa,Kim, Minjung,Lee, Young Wook,Choi, Wonjun,Oh, Won Taek,Park, Q-Han,Han, Sang Woo American Chemical Society 2009 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.131 No.5
<P>The rhombic dodecahedral Au nanocrystals enclosed by 12 {110} facets could be readily prepared without the use of any seeds, surfactants, or foreign metal ions but only with N,N-dimethylformamide as both reductant and solvent.</P>
Jeong Jong Hwan,Kim Jiwon,Choi Chang-Min,Ji Wonjun 대한의학회 2023 Journal of Korean medical science Vol.38 No.32
Background: Although bronchoscopic cryotherapy (BC) is a pragmatic modality for recanalization of central airway obstruction (CAO), the risk of complications, such as bleeding, remains a concern. This study aimed to present the clinical outcomes of BC and evaluate the factors associated with its complications. Methods: In this retrospective study, we reviewed the medical records of patients who underwent BC for CAO at the Asan Medical Center, South Korea. Most sessions were conducted via flexible bronchoscopy under moderate sedation. A multivariate logistic regression analysis was used to identify the factors associated with the success rate and complications. Results: BC was performed in 262 sessions in 208 patients between January 2009 and December 2020. The most common cause of cryotherapy was recanalization of the endobronchial tumor related CAO (233/262, 88.9%). More than partial re-establishment of airway patency was achieved in 211 of 233 (90.6%) sessions. The success rate did not differ significantly in the multivariate logistic regression analysis. The most common complication was intrabronchial bleeding (78/233, 35.5%); however, severe bleeding occurred only in one case (0.4%). Univariate and multivariate logistic regression analyses revealed that diabetes mellitus (odds ratio [OR] = 2.820, P = 0.011), respiratory failure before BC (OR = 3.546, P = 0.028), and presence of distal airway atelectasis (OR = 0.417, P = 0.021) were independently associated with moderate to severe intrabronchial bleeding, while the histologic type of tumor was not related to bleeding. BC for CAO caused by blood clot or foreign body was successful in most cases, and there were no complications. Conclusion: BC is an efficient and relatively safe intervention for patients with CAO. Our findings suggest that diabetes, respiratory failure before BC, and the absence of distal airway atelectasis may be risk factors of moderate to severe intrabronchial bleeding.