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      • KCI등재

        Tensile Properties and Corrosion Behavior of a Dilute Mg–0.5Sn–0.7Al–0.8Zn Alloy Applied for Biomaterials

        Weili Cheng,Yanhui Liu,Yao Zhang,Shuaiju Meng,Srinivasan Arthanari,Hong‑xia Wang,Lifei Wang 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.11

        A novel dilute Mg–0.5Sn–0.7Al–0.8Zn alloy was developed and directly extruded after casting process. The extrudedalloy consisted of fine bimodal grained microstructure, local nano-precipitates micro-region and typical extrusion direction(ED)-tilted texture. A great balance between tensile properties (YS = 262.7 MPa, EL = 26.0%) and corrosion resistance(Pi = 1.57 mm/a) was achieved and discussed in terms of grain size, structure, orientation as well as precipitates and/or corrosionproduct film. As a result, this dilute alloy system shows the great potential to be developed as a biomaterial.

      • KCI등재

        Effects of zinc bearing palygorskite supplementation on the growth performance, hepatic mineral content, and antioxidant status of broilers at early age

        Weili Yang,Yueping Chen,Yefei Cheng,Chao Wen,Yanmin Zhou 아세아·태평양축산학회 2017 Animal Bioscience Vol.30 No.7

        Objective: This study was conducted to investigate effects of zinc (Zn) bearing palygorskite (ZnPal) supplementation on growth performance, hepatic mineral content, and antioxidant status of broilers at early age. Methods: A total of 240 1-day-old Arbor Acres broiler chicks were allocated into 5 treatments with 6 replicates of 8 chicks each. Birds in 5 treatments were fed a basal diet supplemented with 0 (Control group; Analyzed Zn content: 81 mg/kg), 20, 40, 60, and 80 mg/kg Zn as ZnPal for 21 days, respectively. Blood, liver and intestinal mucosa were collected at 21 days of age. Results: Treatments did not affect growth performance of broilers during the 21-day study (p> 0.05). The contents of hepatic Zn and magnesium (Mg) were linearly increased (p<0.001) by ZnPal supplementation. ZnPal inclusion linearly (p = 0.007) reduced malondialdehyde (MDA) concentration in serum. The activity of total superoxide dismutase (T-SOD) in liver increased linearly (p = 0.001) with concentration of ZnPal in diet. ZnPal inclusion linearly (p = 0.036) and quadratically (p = 0.005) increased T-SOD activity, and linearly (p = 0.012) increased copper/zinc superoxide dismutase (Cu/Zn SOD) activity in jejunal mucosa. The maximum responses of hepatic and jejunal antioxidant enzymes activities (T-SOD and Cu/Zn SOD) were found when supplementing the basal diet with 60 mg/kg Zn as ZnPal. Furthermore, ZnPal supplementation quadratically (p = 0.001) increased Cu/Zn SOD activity in ileal mucosa, and its maximum activity was observed in the diet supplemented with 20 mg/kg Zn as ZnPal. Conclusion: ZnPal supplementation did not alter growth performance of broilers. Dietary ZnPal inclusion could increase concentrations of hepatic trace minerals (Zn and Mg) and inhibit lipid peroxidation by reducing serum MDA accumulation, with the optimal dosage of Zn from ZnPal being 80 mg/kg diet (analyzed Zn content in the diet: 165 mg/kg), and 60 mg/kg Zn as ZnPal (analyzed Zn content in the diet: 148 mg/kg) was the optimum dosage for broilers to achieve maximum antioxidant enzyme activities.

      • KCI등재

        Development of Plastic/Gelatin Bilayer Active Packaging Film with Antibacterial and Water-Absorbing Functions for Lamb Preservation

        Shijing Wang,Weili Rao,Chengli Hou,Raheel Suleman,Zhisheng Zhang,Xiaoyu Chai,Hanxue Tian 한국축산식품학회 2023 한국축산식품학회지 Vol.43 No.6

        In order to extend the shelf life of refrigerating raw lamb by inhibiting the growth of microorganisms, preventing the oxidation of fat and protein, and absorbing the juice outflow of lamb during storage, an active packaging system based on plastic/gelatin bilayer film with essential oil was developed in this study. Three kinds of petroleumderived plastic films, oriented polypropylene (OPP), polyethylene terephthalate, and polyethylene, were coated with gelatin to make bilayer films for lamb preservation. The results showed significant improvement in the mechanical properties, oxygen, moisture, and light barriers of the bilayer films compared to the gelatin film. The OPP/gelatin bilayer film was selected for further experiments because of its highest acceptance by panelists. If the amount of juice outflow was less than 350% of the mass of the gelatin layer, it was difficult for the gelatin film to separate from lamb. With the increase in essential oil concentration, the water absorption capacity decreased. The OPP/gelatin bilayer films with 20% mustard or 10% oregano essential oils inhibited the growth of bacteria in lamb and displayed better mechanical properties. Essential oil decreased the brightness and light transmittance of the bilayer films and made the film yellow. In conclusion, our results suggested that the active packaging system based on OPP/gelatin bilayer film was more suitable for raw lamb preservation than single-layer gelatin film or petroleum-derived plastic film, but need further study, including minimizing the amount of essential oil, enhancing the mechanical strength of the gelatin film after water absorption.

      • KCI등재

        Hepatocyte growth factor (HGF) promotes cardiac stem cell differentiation after myocardial infarction by increasing mTOR activation in p27kip haploinsufficient mice

        Ningtian Zhou,Yunle Wang,Weili Cheng,Zhijian Yang 한국유전학회 2015 Genes & Genomics Vol.37 No.11

        Myocardial infarction (MI) is a major cause of death worldwide. The treatment of MI has improved during the last decade; however, the loss of myocytes remains a problem because the cells cannot be renewed. Cardiac stem cells were recently discovered and were thought to represent a promising treatment for MI. However, the efficiency of cardiac stem cell differentiation into myocyte is not sufficient. Hepatocyte growth factor (HGF) is related to the differentiation and proliferation of cardiac stem cells. p27kip1 is a potent cell cycle inhibitor in most organs, especially the heart. In this study, we investigated the relationship among p27, HGF and cardiac stem cells in post-MI cardiac repair. We found that p27 haploinsufficient mice exhibited preserved cardiac function and improved cardiomyocyte renewal compared with wild-type mice. In addition, p27 haploinsufficiency may not increase cardiac stem cell proliferation but could improve their differentiation by increasing mammalian target of rapamycin expression.

      • KCI등재

        Functional Graphene Derivatives for Chemotherapy-Based Synergistic Tumor Therapy

        Xinyu Cui,Wenlong Cheng,Weili Xu,Wei Mu,XIAOJUN HAN 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.11

        Starting from simplex drug delivery system, the graphene oxide (GO) and reduced GO (rGO) materials have been developed to be "combo" nanoplatforms containing multiple therapeutic modalities, such as the targeted drug delivery, imaging, as well as photothermal therapy (PTT) due to their distinctive physical/chemical and optical properties including excellent biocompatibility, modifiable active groups, ultra-large surface area, and intense photothermal effect. The graphene-based nanoplatforms were used for the stimuli-responsive nanocarriers, showing excellent therapeutic effects activated by endogenous stimuli including low pH, overexpressed enzymes, biomolecules, elevated glutathione, and exogenous stimuli including light, magnetic/electric field, and ultrasound. More importantly, for multimodal synergistic therapy originated from the enhanced collaborative interactions among several monotherapy types, the obtained remarkable super-additive effects were not the results just through single therapy or their theoretical combination. In this review, the recent progresses of smart graphene-based nanoplatforms for integrated cancer therapy and bio-imaging are presented. Current challenges and future perspectives of graphene-based nanoplatforms in the biomedical field are also discussed.

      • Co-precipitation synthesis and characterization of Bi3+, Eu3+ co-doped nanocrystal Gd2WO6 phosphors.

        Tian, Yue,Chen, Baojiu,Hua, Ruinian,Cheng, Lihong,Zhong, Haiyang,Sun, Jiashi,Wang, Bo,Wan, Jing,Lu, Weili,Jang, Kiwan American Scientific Publishers 2010 Journal of Nanoscience and Nanotechnology Vol.10 No.3

        <P>Eu3+ single-doped and Bi3+/Eu3+ co-doped nanocrystal Gd2WO6 phosphors were successfully synthesized via a co-precipitation reaction. The structure and morphology of the phosphors were characterized by using X-ray powder diffraction (XRD) and field emission scanning electron microscopy (FE-SEM). The influence of Bi(3+)-doping concentration on the excitation and emission spectra was studied. It was found that the introduction of Bi3+ can greatly affect the charge transfer band and the luminescence intensity of Eu3+ but does not cause a change in the profile of emission spectra of Eu3+.</P>

      • KCI등재

        Enhanced Strength-Ductility Synergy in Mg-0.5 wt%Ce Alloy by hot Extrusion

        Hui Yu,Yu Liu,Ya Liu,Dongliang Wang,Yuling Xu,Binan Jiang,Weili Cheng,Lixin Huang,Weineng Tang,Wei Yu 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.7

        The microstructure and mechanical properties of micro-alloyed Mg-0.5 wt%Ce alloys are investigated systemically in this study. It shows that Mg-Ce binary system is very sensitive to extrusion temperature. On the one hand, the high tensile yield strength (TYS) of 343 MPa was obtained by extrusion at 250 °C mainly due to the combined effects of profuse nano-precipitation phase, grain refinement, texture strengthening and high-density dislocation; On the other hand, the excellent elongation of 30% was acquired by extrusion at 300 °C resulting from the elimination of dislocations as well as the modification of texture.

      • KCI등재

        The evolution of permeability and gas composition during remote protective longwall mining and stress-relief gas drainage: a case study of the underground Haishiwan Coal Mine

        Wei Li,Yuan-ping Cheng,Pin-kun Guo,Feng-hua An,Ming-yi Chen 한국지질과학협의회 2014 Geosciences Journal Vol.18 No.4

        The mining of protective coal seams can cause changesin geostress, leading to changes in the permeability of coal rock and creatingfavorable conditions for gas extraction from coal seams. Atthe Haishiwan Coal Mine, field tests using remote protective coalseam mining were performed in the protected layer, which is richin CO2 gas. In remote protective longwall mining, the permeabilityand composition of extracted stress-relief gas can vary. Under theconditions of remote protective longwall mining, the permeabilityof a protected coal seam can be generally described by the Liumodel. During protective layer mining, the permeability of theprotective layer increases rapidly with the release of stress, thendecreases gradually with the recovery of the geostress. However,matrix shrinkage and decreased pore pressure caused by CO2 desorptionfrom coal seams also cannot be ignored when considering thefactors that affect the permeability. Thus, it is necessary to appropriatelyconfigure the cross-measure boreholes in advance to drainthe stress-relief gas during remote protective layer mining. StressreliefCO2 gas extraction presents multiple consecutive peaks. TheNo. 2 coal seam has different trap pressure systems as CO2 migratesinto the coal seam. The protected seam experiences different effectivestresses during protective layer mining, and the permeabilitiesappear to periodically increase due to differences in the originalpermeability. The various permeability and diffusion coefficientsfor CO2 and CH4 in coal induce CO2 and CH4 fractionation in theroof and floor of the No. 2 coal seam.

      • KCI등재

        Paste Stability and Desizability of Poly(Sodium Allyl Sulfonate)-g-Starch-g-Poly(Ethyl Acrylate) Used as Warp Sizing Agent

        Wei Li,Qian Liu,Guoyu Zhang,Xuedong Cheng,Yingfeng Wang,Zhenzhen Xu 한국섬유공학회 2022 Fibers and polymers Vol.23 No.8

        This work aimed to evaluate the paste stability and desizability of new starch grafted copolymer [poly(sodium allylsulfonate)-g-starch-g-poly(ethyl acrylate)] (PSAS-g-starch-g-PEA) for providing an important supporting role in sizingapplication. The PSAS-g-starch-g-PEA samples were prepared by grafting reaction of acid-thinned starch (AHS) with SASand subsequent with EA in water phase. The PSAS-g-starch-g-PEA granules were characterized by Fourier transforminfrared spectroscopy and scanning electron microscopy. Also, paste stability was assessed and desizability was investigatedin terms of desizing efficiency, swelling ability of the film and time interval for the break of starch film in water. Comparedwith control AHS, the PSAS-g-starch-g-PEA had higher paste stability, desizing efficiency and swelling ability, and lowertime interval required, concluding that the PSAS and PEA branches could promote the paste stability and desizability ofstarch. Increasing the number of both branches facilitated the paste stability and desizability. PSAS-g-starch-g-PEA displayedpotential value in textile sizing field.

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