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Theresia Santi 대한백신학회 2023 Clinical and Experimental Vaccine Research Vol.12 No.3
Purpose: We reported a survey-based study assessing the parental intention to vaccinate children of 5 to 7 years old against coronavirus disease 2019 (COVID-19). The aim of this study is to assess factors influencing the parental intention to vaccinate their children against COVID-19. Materials and Methods: This study adopted a cross-sectional design, held at the public health center of Senen district, Jakarta, Indonesia from November 1–30, 2022. The off-line questionnaires were distributed via the school administrator to all eligible parents. Factors associated with intention to vaccinate were analyzed with the regression logistic models. Results: Of the 435 parents in this study, 215 had already vaccinated their children against COVID-19 (49.4%), and the overall intention of the participants to vaccinate was 69.7%. Factors associated with intention to vaccinate the children against COVID-19 were parental employment status, parental COVID-19 vaccine status and concern of contracting COVID-19. Parents who are employed, had completed vaccines with COVID-19 booster vaccine, and had concern of their children contracting COVID-19 were more likely to vaccinate their children (odds ratio [OR], 2.10; 95% confidence interval [CI], 1.22–3.69; p=0.011; OR, 2.15; 95% CI, 1.21–3.83; p=0.013; OR, 2.40; 95% CI, 1.34–4.30; p=0.004, respectively). Concern on the vaccine’s side effects was negatively associated with the willingness to vaccinate. Conclusion: This study showed that childhood COVID-19 vaccine only covered half of the population, with parental intentions for childhood COVID-19 vaccination being high, reaching almost two-thirds of the study participants. Factors influencing parental intentions were employment status, parental COVID-19 vaccine status, concerns about COVID-19 and concerns about vaccine side effects.
Theresia Santi,Veli Sungono,Lina Kamarga,Baringin De Samakto,Ferry Hidayat,Feronica Kusuma Hidayat,Magy Satolom,Anita Permana,Irawan Yusuf,Ivet Marita Suriapranata,Juandy Jo 대한백신학회 2022 Clinical and Experimental Vaccine Research Vol.11 No.2
Purpose: This study was performed to investigate humoral immune response and adverse events upon the heterologous prime-boost with a single dose of the mRNA-1273 vaccine among fully CoronaVac-vaccinated, infection-naïve healthcare workers in Indonesia. Materials and Methods: One hundred twenty-five eligible healthcare workers were recruited from one hospital for this prospective cohort study. Blood collection was conducted twice, i.e., on 7 days before and 28 days after the booster vaccination. The titer of anti-SARS-CoV-2 receptor-binding domain (RBD) antibodies was quantified accordingly. The post-vaccination adverse event was recorded for both CoronaVac and mRNA-1273 vaccinations. Any breakthrough infection was monitored during the follow-up period. Wilcoxon matched-pairs signed rank test was used to test differences between groups. Results: A significant increase was observed in the titer of anti-SARS-CoV-2 RBD antibodies upon receiving the mRNA-1273 booster (geometric mean titers of 65.57 and 47,445 U/mL in pre- and post-booster, respectively), supporting the argument to use heterologous prime-boost vaccination to improve the protection against COVID-19 in a high-risk population. The mRNA-1273 vaccine, however, caused a higher frequency of adverse events than the CoronaVac vaccine. Nonetheless, the adverse events were considered minor medical events and temporary as all subjects were not hospitalized and fully recovered. Of note, no breakthrough infection was observed during the follow-up to 12 weeks post-booster. Conclusion: The heterologous prime-boost vaccination of healthcare workers with a single dose of the mRNA-1273 vaccine generated a significant elevation in humoral immune response towards RBD of SARS-CoV-2 and was associated with a higher frequency, but minor and transient, adverse events.
Effects of Sleep Deprivation on Vigilance, Attention, and Performance During Simulated Train Driving
Clara Theresia,Hardianto Iridiastadi,Gradiyan Budi Pratama 대한산업공학회 2021 Industrial Engineeering & Management Systems Vol.20 No.1
Sleep deprivation has been cited as a major factor that plays an important role in many incidents in the transportation sector. Sleep-deprived train drivers is a fairly common phenomenon in Indonesia, with local reports indicating a good percentage of train drivers who are sleep deprived prior to work. The present study was aimed at quantifying the effects of sleep deprivation on alertness and performance during prolonged simulated train driving. A total of 12 subjects participated in this study and were asked to sleep for approximately 2 h (sleep deprived) and 8 h (normal sleep) the night before the experimental day. The experiment consisted of driving a train simulator for 4 h on a monotonous route. Fatigue and sleepiness were assessed using Psychomotor Vigilance Task (PVT) and Sustained Attention Test (SAT), conducted before and after the driving simulation. Subjective levels of fatigue and sleepiness were determined using questionnaires, while driving performance was measured based on the number of speed-limit violations. Results of this study showed that two hours of sleep was characterized with an initial subjective fatigue and sleepiness measures that were up to two to three times greater than the normal sleep condition. This condition also resulted in poorer driving performance (75% increase in the number of speeding error). While the effects of sleep deprivations on the performance of train driving is probably obvious, the quantitative effects have not been addressed extensively in the literature. It is concluded in this study that the effects of excessive sleep deprivation on fatigue and sleepiness varies, depending on the measures used.
Santi Theresia,Kamarga Lina,De Samakto Baringin,Jo Juandy 대한감염학회 2022 Infection and Chemotherapy Vol.54 No.4
It remains unknown whether the Indonesian healthcare workers (HCWs) who had received two doses of CoronaVac vaccine and one dose of mRNA-1273 booster could be protected during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron wave. In total, 125 infection-naïve and 10 previously infected HCWs were recruited. The mRNA-1273 booster substantially increased titer of anti-SARS-CoV-2 spike protein receptor-binding domain antibodies. However, the monitoring revealed that 34 out of 125 infection-naïve (27.2%) and 3 out of 10 previously infected HCWs (30.0%) were infected during the Omicron wave. All infected HCWs were either asymptomatic or having mild coronavirus disease 2019 (COVID-19) and subsequently fully recovered, supporting the heterologous prime-boost strategy against COVID-19.
정철의 「훈민가」와 라자 알리 하지의 「12장 구린담」비교 연구
테레시아 마가렛(Theresia Margareth) 한국시조학회 2017 시조학논총 Vol.46 No.-
본 논문의 주제는 정철의 「훈민가」와 라자 알리 하지의 「12장 구린담」의 작품 비교이다. 정철의 「훈민가」는 16세기 시조이다. 백성들을 교육하기 위한 교훈시조이다. 유교 사상을 바탕으로 조선의 생활 방식과 언어를 가지고 만든 시조이다. 한편 라자 알리 하지의 「12장 구린담」은 19세기 구린담이다. 인도네시아 고전 시가를 가지고 백성들을 교육하기 위한 교훈 구린담이다. 네덜란드 식민지를 당한 인도네시아 백성들을 위해 이슬람교 사상을 바탕으로 만든 교훈 구린담이다. 한국과 인도네시아의 교훈 시가를 가지고 비슷한 점을 비교하였다. II장에서 시조와 구린담 두 시가의 개념과 특징 그리고 정철과 라자 알리 하지의 생애를 알아보았다. III장에서는 두 작품의 내용을 전체 구성에 따라 세 부분으로 나누어 비교 분석하였고, IV장은 결론이다. 서로 다른 문화권의 두 작품을 비교하고 비슷한 점을 찾아서 연구하였다는 점에서 비교문학의 가능성을 열어보았다. This paper theme is poem’s comparative view of 「Huminga」from Jeongcheol and 「12 Gurindam」from Raja Ali Haji. <Hunminga> was written by Jeongcheol in 16 centuries. This is an education poem that was made to educate the Joseon people. The sijo was made based on Confucianism and the people’s daily life thus use daily language which make the people easy to understand. In another hand, 「12 Gurindam」was written by Raja Ali Haji in 19 centuries. He used the old Indonesian poetry style for educating the people. He used literature and daily language so that the people can understand Islam easily. I would like to compare these two education poems because they have similar purpose, educating the people. In the part II, I would like to explain about the concept and characteristic of sijo as well as the Jeongcheol’s short biography. And I would like to explain about the concept and characteristic of gurindam as well as the Raja Ali Haji’s short biography. I would like to compare the poems in part III and make the conclusion in part IV.
동물의 혈액으로부터 정제된 아미노산 사료첨가제가 이유자돈의 성장과 면역 반응에 미치는 효과
Najuma Joshi,Theresia Galuh Wandita,남인식,박해성,황성구 강원대학교 동물자원공동연구소 2017 동물자원연구 Vol.28 No.4
The present study investigated the effects of dietary supplementation of purified amino acid (PAA) isolated and purified from animal slaughter house blood on growth performance and immune response of weanling piglets. A total of fifteen, 28 days old, weaned pigs were randomly distributed into three treatment groups, 5 pens per treatment (one head per pen). Each experimental diet was provided to five piglets per group (T0, 0% PAA; T1, 0.1% PAA; T2, 0.5% PAA). The feed consumption was calculated daily and body weight on a weekly basis. The blood samples were analyzed for plasma concentration of biochemical parameters and cytokines using ELISA Kit assay. Pigs fed with the 0.5% PAA have greater average daily weight gain (ADG) and feed efficiency (FE) as compared to those of T0 and T1. However, ADG and FE of T0 and T1 have no remarkable differences. The plasma cytokine levels were lower in T2 as compared to T0 and T1. The blood parameters like total bilirubin, blood urea nitrogen (BUN), glutamate oxalate transaminase (GOT) and glutamate pyruvate transaminase (GPT) were within the normal range in all the treatment groups. The study indicated that supplementation of 0.5% PAA have positive effect on the growth performance of the weanling pigs. Moreover, supplementation of the amino acid isolated and purified from animal slaughter house blood has no adverse effect on palatability of the feed and health of the animals.