李建昌의 「李卓吾贊」에 대하여

김용태(Kim Yang-Tae) 동양한문학회(구 부산한문학회) 2008 동양한문학연구 Vol.26 No.-

  본고는 이희목 교수에 의해 십수년 전에 보고되었으나, 그 사이 학계에서 ‘잊혀진’ 자료였던 이건창의 「이탁오찬」이란 글의 존재를 학계에 환기하고, 그 내용과 의의를 검토하여 이건창 문학을 새롭게 이해하는 시각을 제시하려는 목적에서 집필되었다. 「이탁오찬」은 陽明左派의 성립에 중요한 역할을 하였던 李贄를 칭송하는 내용을 담은 글이기에, 최근 들어 그 열기가 더해지고 있는 양명좌파와 公安派의 수용에 대한 연구에 있어 매우 중요한 자료가 아닐 수 없다.<BR>  「이탁오찬」은 이건창이 20대에 지은 글인데, 이 당시 내면적으로 울분상태에 있던 이건창은 양명좌파 및 공안파를 접하면서 많은 위안을 받을 수 있었다. 이후 이건창은 양명좌파 및 공안파와 일정한 거리를 두게 되지만, 양명좌파 및 공안파의 사유를 자신의 문학적 목표와 실천의 자양분으로 적절히 활용하였다. 이러한 점은 이건창 문학을 주로 ‘古文’적 관점에서 접근 하였던 기존의 연구에서 주목하지 못했던 부분이라 할 수 있는데, 실상 이건창 문학이 위대한 까닭은 양명좌파, 공안파, 동성파 등등의 외부적 요인을 주체적으로 활용하여 자신만의 독특한 색깔로 재창조했다는 점에서 찾아져야 할 것이다. 그리고 이러한 점은 양명좌파와 공안파의 수용에 있어 ‘주체’의 측면을 제대로 고려하지 않는 최근의 연구경향에 대해서도 시사하는 바가 적지 않다고 할 수 있다.   The material, 「lee tak oh chan(李卓吾贊)」, was reported approximately a dozen years ago by a Professor Lee, Hee-mok. But this material has been "forgotten" in the academic society. This abstract has been created with an aim to propose a new point of view to understand the literature of Lee, Kun-chang(李建昌) by reviewing the 「lee tak oh chan」. 「lee tak oh chan」 contains materials that look up to Li zh? who had played an important role in establishing a Radical Yang-ming school, which cannot be a crucial material in the sense that recently its academic heat has been increasing toward Radical Yang-ming school and Gong-an School.<BR>  「Lee tak oh chan」 was made by Lee, Kun-chang in his twenties. At the time, Lee, Kun-chang who was in depression of his days had been consoled much by Radical Yang-ming school and Gong-an School. Since then, he placed a certain distance to Radical Yang-ming school and Gong-an School, however he applied appropriately Radical Yang-ming school and Gong-an School to sources of nutrition of literary object and performance. These points were something that at-the-time research hardly took notice of having the viewpoint to access to Lee, Kun-chang literature based upon "Guwen(Classical literary Style 古文)". In fact, the reason, we have to understand, that the greatness of Lee, Kun-chang literature is that it recreated outer factors of Radical Yang-ming school, Gong-an School, Dong-sung School, etc subjectively in its unique color.<BR>  And, in this respect, it suggests us a lot in the sense that even recent research trend tends to hardly focus upon "subjectivity" in the absorbtion of Radical Yang-ming school and Gong-an School.

腹部疼痛에 應用되는 經?에 對한 文?的 調査

金良奎,崔容泰 慶熙大學校韓醫科大學韓醫學硏究所 1981 慶熙韓醫大論文集 Vol.4 No.-

Identification of Redox Sensitive Proteins in Prdx II Deficient Red Blood Cells

Tae‐Hoon Lee,Hee‐Young Yang,Hoon‐In Choi,Gia‐Buu Tran,Ung Yang 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

Red blood cells (RBCs) have been studied as models for infectious diseases, various symptoms of anemia, hemolysis, and erythrocyte aging. Although do not directly affect RBCs, other diseases may cause RBC physiological alterations that could be advanced for diagnostic aim or to convince better understanding of a certain pathological pattern. In this study, comparative RBC proteomics between healthy and abnormal conditions involve to promote aging related‐biomarker discovery. Peroxiredoxin II (Prdx II; a typical 2‐Cys Prdx) has been originally isolated from erythrocytes, and its structure and peroxidase activity have been adequately studied. Mice absent to Prdx II proteins had heinz bodies in their peripheral blood, and morphologically aged cells were detected in the dense RBC fractions, which contained markedly higher levels of reactive oxygen species (ROS). In addition, a labeling experiment with the thiol‐modifying reagent biotinylated iodoacetamide (BIAM) in Prdx II‒/‒ mice revealed that a variety of RBC proteins were highly oxidized. To identify oxidation‐sensitive proteins in Prdx II‒/‒ mice, we performed RBC comparative proteome analysis by nano‐UPLC‐MSE shotgun proteomics with relative protein quantitative analysis. We found oxidation‐sensitive 18 membrane and 41 cytosol proteins from 32 and 85 peptides containing cysteine oxidation, and analyzed comparative expression pattern in healthy RBCs of Prdx II+/+ mice (W1), healthy RBCs of Prdx II‒/‒ mice (K1), and abnormal RBCs of Prdx II‒/‒ mice (K2). These proteins belonged to cellular functions related with RBC lifespan maintain, such as cytoskeleton, stress‐induced proteins, amino acid/nucleic acid metabolic enzymes, signal transduction, and molecular transporters. Furthermore, protein networks among identified oxidation sensitive proteins were analyzed to associate with aging consequence. Consequently, we expected that RBC proteome may provide clues to understand redox‐imbalanced diseases.

University Students' Perceptions about NESPs and NNESPs in EMCs

Yang Tae-sun 한국사회언어학회 2012 사회언어학 Vol.20 No.2

Yang Tae-sun. 2012. University Students' Perceptions about NESPs and NNESPs in EMCs. The Sociolinguistic Journal of Korea 20(2). pp. 291-312. The purpose of this study was to investigate Korean university students' perceptions about NESPs (Native English Speaking Professor) and NNESPs (Non-native English Speaking Professor) in EMCs (English Medium Course) to suggest better ways to implement EMCs in university settings. 100 university students who had an experience in taking EMCs with both NESPs and NNESPs answered the questionnaire and 30 students out of them were also interviewed to consolidate the data. Students expressed that they could benefit from NESPs in the area of language. On the other hand, they thought that they could have more chances to broaden content knowledge with the help of NNESPs. Based on the results of the study, the following suggestions were made for NESPs and NNESPs to implement EMCs in a successful way: NESPs should deepen their knowledge of content areas. NNESPs should use a monitoring service at the university to get comments on their teaching, participate in one-on-one tutoring sessions to practice English with NESPs, participate in meetings to get effective teaching tips from experts, and the university should regularly conduct needs surveys and do ongoing analyses of students' and professors' needs to provide more customized EMCs.

Targeting Multiple Myeloma Cell Death with Polyphenol EGCG

Tae‐Hoon Lee,Hee‐Young Yang,Hoon‐In Choi,Ung Yang,Kyoung‐Jin Chung,Lina Ren 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

(‐)‐Epigallocatechin 3‐gallate (EGCG) is a potent antioxidant polyphenol in green tea that acts as an anticancer agent via both direct and indirect pathways. Although the relationship between EGCG’s anticancer effects and its antioxidant activity is not fully understood, it is known that EGCG stimulates production of reactive oxygen species (ROS), which induce oxidative stress leading to cell death. In IM9 multiple myeloma cells, EGCG acted in a dose‐ and time‐dependent manner to induce apoptotic cell death. Among the antioxidant enzymes expressed in IM9 cells, levels of peroxiredoxin (Prdx) V were selectively and significantly reduced by EGCG. Moreover, the ROS scavenger NAC completely inhibited EGCG‐induced apoptosis and PrdxV reduction, while overexpression of PrdxV, but not a PrdxVC48S mutant, protected IM9 cells from EGCG‐induced apoptosis. EGCG‐induced reductions in cell viability and PrdxV levels were also observed in primary CD138+ multiple myeloma cells from patients. These results suggest that PrdxV is a key target via which EGCG mediates its anticancer effects.

A Study on the Functionality of Halophytes from Coast area of Jeollanam-do

Tae-Man Ha,Yang-Joon An,Mi-Yeong Shin,Sook Park,Hak-Jae Park,Hyo-Jeong Kang,Su-Jeong Choi,Jae-Yeong Yu,Ji-Yun Jeon,Gyu-Yeon Oh 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

This study was undertaken to improve the perceived value of halophytes and contribute to the activity of the local economy by analyzing the antioxidant activity and mineral content of Suaeda japonica, Tetragonia tetragonoides, and Spergularia marina that grow wild on the mud flats and coastal areas. The total phenolic compound content found in each order is as follows: Suaeda japonica (3.674∼5.989 mg TAE/g dry wt.), Tetragonia tetragonoides (2.515∼4.471 mg TAE/g dry wt.), and Spergularia marina (2.450∼4.067 mg TAE/g dry wt.); DPPH radical scavenging and ABTS cation radical scavenging activities were also recorded in the same order. In the case of minerals, Iron(Fe) was relatively high in Suaeda japonica (960.1∼1,346.7 mg/kg), Manganese(Mn) in Tetragonia tetragonoides (197.1∼574.8 mg/kg), and Zinc(Zn) was relatively high in Spergularia marina (63.19∼216.56 mg/kg). It was confirmed that the mineral content of Suaeda japonica, Tetragonia tetragonoides, and Spergularia marina was significantly higher than that of Chinese cabbage, lettuce, leek, and spinach.

Proteomic Analysis of Thiol Specific‐Protein Oxidation

Tae‐Hoon Lee,Hee‐Young Yang,Hoon‐In Choi,Gia‐Buu Tran,Ung Yang 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

Peroxiredoxin II (Prdx II; a typical 2‐Cys Prdx) has been originally isolated from erythrocytes, and its structure and peroxidase activity have been adequately studied. Mice absent to Prdx II proteins had heinz bodies in their peripheral blood, and morphologically abnormal cells were detected in the dense red blood cell (RBC) fractions, which contained markedly higher levels of reactive oxygen species (ROS). In this study, a labeling experiment with the thiol‐modifying reagent biotinylated iodoacetamide (BIAM) in Prdx I‒/‒ mice revealed that a variety of RBC proteins were highly oxidized. To identify oxidation‐sensitive proteins in Prdx II‒/‒ mice, we performed RBC comparative proteome analysis in membrane and cytosolic fractions by nano‐UPLC‐MSE shotgun proteomics. We found oxidation‐sensitive 54 proteins from 61 peptides containing cysteine oxidation, and analyzed comparative expression pattern in healthy RBCs of Prdx II+/+ mice, healthy RBCs of Prdx II‒/‒ mice, and abnormal RBCs of Prdx II‒/‒ mice. These proteins belonged to cellular functions related with RBC lifespan maintain, such as cytoskeleton, stress‐induced proteins, metabolic enzymes, signal transduction, and transporters. Furthermore, protein networks among identified oxidation sensitive proteins were analyzed to associate with various diseases. Consequently, we expected that RBC proteome may provide clues to understand redox‐imbalanced diseases.

Peroxiredoxin V Regulates Aco2, Acadm, and Acox1 Activity in Hypoxic Kidney

Tae‐Hoon Lee,Hee‐Young Yang,Joseph Kwon,Hoon‐In Choi,Lina Ren,Ung Yang,Byung‐Ju Park,Zae Young Ryoo 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

Peroxiredoxin V, an atypical thioredoxin peroxidase, is widely expressed in mammalian tissues. In addition, Prdx V is localized in mitochondria, peroxisome, cytosol, and nucleus. Prdx V has been reported to protect a wide range of cellular environments as antioxidant enzyme, and its dysfunctions may be implicated in several diseases, such as cancer, inflammation, and neurodegenerative disease. Identification and relative quantification of proteins affected by Prdx V may help identify novel signaling mechanisms that are important for oxidative stress response. However, the role of Prdx V in the modulation of hypoxia‐related cellular response is not studied yet. In order to examine the function of endogenous Prdx V in hypoxic condition in vivo, we generated a transgenic mouse model with Prdx V siRNA expression controlled by U6 promoter. Of many tissues, the knockdown of Prdx V expression was displayed in kidney, lung, and liver, but not spleen and skin. We conducted on the basis of nano‐UPLC‐MSE proteomic study to identify the Prdx V‐affected protein networks in hypoxic kidneys. In this study, we identified protein networks associated with oxidative stress, fatty acid metabolism, and mitochondrial dysfunction. Our results indicated that Prdx V affected to regulation of kidney homeostasis under hypoxia stress.

國産 羊毛의 物性에 관한 硏究

楊澈坤,金洪均,安泰煥 成均館大學校 1981 論文集 Vol.30 No.-

Physical properties of wool are closely related to species of sheep, locality of production and feeding conditions. This paper describes an basic investigation of physical properties of Korean wool. Specific properties affected by crimp were also investigated. The experiment for physical properties of Korean wool was carried out by the conventional method and its for specific properties was done by load extension test. The results of those were as follows; 1. As for fineness values of wool, the quality numbers of Corriedale wool was 56's and its of Romney marsh wool was 46's-48's. 2. As for fineness, mean length, distribution of fibre length, strength and elongation of Corriedale wool were superior to those of standard wool. 3. It was found that strength per denier and elastic limit strength of both species were sligtly higher than its of standard wool 4. Uncrimping force was 1/15-1/21 of yield stress, Recovering of uncimping force and enegy in Korean wool was also significant. 5. Corriedale wool has good quality of which uncrimping force and energy would be changed by crimp. Characteristics of Corriedale wool; elasticity, softness and bulking capacity of wool itself were slightly higher than its of Romney marsh wool

캠기반 요골동맥 펄스 시뮬레이터 개발

양태헌 韓國交通大學校 2022 한국교통대학교 논문집 Vol.57 No.-

The goal of this study is to develop a small and economical pulsation simulator that can generate various radial artery pressure waveforms. For this, many pulse waveforms were collected from the subjects using a robotic pulse pressure measurement system, and standard pulse waveforms of the subjects were defined from the data collected using a mathematical model. This standard pulse waveform was used to design and fabricate the cam profile. Using the fabricated cam, a pneumatic pulse waveform generating system based on DC motor and cam-follower mechanism was developed. The developed pulsation simulator was developed to include a mechanism to control the magnitude of the pulse pressure and heart rate, and a real-time pulse display. To verify the performance of the developed pulsation simulator, a series of tests were performed on the waveform generated by the pulsation simulator while varying the pressure level and heart rate using a robotic pulse pressure measurement system. As a result of the radial augmentation index (AI) and phase analysis between the human standard pulse waveform and the waveform generated by the simulator, it was confirmed that the error ratio was small enough that the proposed simulator can generate a human pulse waveform.