http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
가정의학과 외래 우울증환자에서 moclobemide의 안전성 및 유효성 평가를 위한 시판후조사
김영식,이근미,김병성,신호철,성은주,이상엽,문유선,송상욱,김철환,선우성,Kim, Young-Sik,Lee, Keun-Mi,Kim, Byung-Sung,Shin, Ho-Cheol,Sung, Eun-Ju,Lee, Sang-Yeoup,Moon, Yoo-Sun,Song, Sang-Wook,Kim, Cheol-Hwan,Sunwoo, Sung 대한임상약리학회 2002 臨床藥理學會誌 Vol.10 No.1
Background : Depression is quite a common disease in primary care however, studies for the safety and effectiveness of antidepressants in primary care setting are rare in Korea. Objectives : This multi-centered post-marketing study was performed to evaluate the safety and effectiveness of Moclobemide and to find out the factors related to the adherence among patients with depression in family practice. Methods : A total of 386 patients were enrolled from July 1999 to January 2000 by twenty family doctors from fifteen family practice centers. They were prescribed Moclobemide and were reevaluated at the 4th, 8th, and l2th week. Evaluation of compliance, safety and effectiveness were performed with pre-made, structured self-reported questionnaires. Evaluation of effectiveness was also performed utilizing self-rating depression scale (SDS). Results : Among 386 patients, safety was evaluated in 310 patients and effectiveness was evaluated in 239 patients. During the first 12 weeks, the number of subjects continuing with Mocclobemide was 136(37.1%). 141 subjects (38.4%) discontinued taking the drug and 90 subjects (24.5%) dropped out at the 12th week. Considering drop-out patients as ineffective cases, overall effectiveness was estimated to be 84.5%. Symptoms improved with time in patients whose follow-up were completed (P<0.01). The SDS score decreased by an average of ${6.8{\pm}9.1(12.2{\pm}19.1%)}$ after 12 weeks(p<0.01). During the study, 33(10.6%) subjects reported adverse events. The most commonly reported adverse events, in descending order, were dizziness(2.3%), headache(1.6%), insomnia(1.3%), facial edema(1.3%), constipation(1.0%), nausea(1.0%) and tremor(1.0%). The main reasons for discontinuing antidepressants were attributed to improvement of symptoms and manifestation of adverse events. Conclusion : The percentage of adherence at 12th week of Moclobemire among patients suffering from depression in the family practice outpatient clinic was shown to be 49%. The antidepressant effect and safety of Moclobemide was relatively superior.
이은재(Eun-Jae Lee),백승택(Seung-Taek Baek),최호석(Ho-Seok Choi),김영우(Young-Woo Kim),심재혁(Jae-Hyeok Shim),송상욱(Sang-Wook Song) 전력전자학회 2019 전력전자학술대회 논문집 Vol.2019 No.7
국내 전력 계통은 경제의 성장과 더불어 생활 수준의 향상에 따라 지속적인 증설과 발전이 이루어졌다. 전력설비의 밀도 측면에서 비추어보면 미국이나 일본 대비 적게는 2배에서 많게는 4배에 이르는 최고 수준의 설비 밀도를 보이고 있다. 또한 전체 전력 생산량의 40%이상이 수도권에서 소비되고 있지만 발전설비는 최대 전력 수요지인 수도권과 먼 해안에 인접한 지역에 편재되어 있기 때문에 발생하는 수요와 공급지의 불균형, 장거리 선로를 통한 전력 전송에서 야기되는 전력계통 운영 측면에서의 문제가 발생하게 된다. 최근 화두가 되고 있는 원전 축소, 노후 화력 발전소 정지, 송전선로 경과지에서의 건설 고압 송전선로 건설 반대 등의 요인으로 인하여 전력계통을 최대한 효율적이고 안정적으로 운영하여야 하는 대전제를 만족시키기 위한 방안으로 기존 AC 기반의 계통 설비에 전력변환기술을 기반으로 하는 DC 계통 및 FACTS 설비의 확대 적용하는 방안이 제시되고 있다. 본 논문에서는 다가올 MV급 이상의 전력변환설비의 개념 및 개발 현황에 대한 소개를 하고자 한다.
1995년과 2000년의 학동기와 2003년 학동전기 소아에서의 아토피피부염의 역학적 변화에 관한 전국적인 연구
오재원 ( Jae-Won Oh ),김규언 ( Kyu-Earn Kim ),편복양 ( Bok-Yang Pyun ),이혜란 ( Hae-Ran Lee ),정지태 ( Ji-Tae Choung ),홍수종 ( Soo-Jong Hong ),박강서 ( Kang-Seo Park ),이수영 ( Soo-Young Lee ),송상욱 ( Sang-Wook Song ),김철홍 ( C 대한소아알레르기호흡기학회 2003 소아알레르기 및 호흡기학회지 Vol.13 No.4
Objective : Atopic dermatitis is a chronically relapsing inflammatory skin disease. However, little is known about the prevalence of atopic dermatitis outside of North America and Europe. We evaluated the nationwide prevalence of atopic dermatitis with th