An Improved Collaborative Filtering Recommendation Algorithm

Shulin Liu 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.3

An improved CF algorithm based on the classification of items is introduced to overcome the problems caused by the data sparseness and inaccuracy of the user neighbors. The new algorithm first rates the unrated items by applying the item classification, and then calculates the user similarity within classes for nearest-neighbors, after which it could recommend the items based on the final prediction.

A UPS BASED ON A NEW SPWM GENERATOR

Liu Shulin,Liu Jian 전력전자학회 1998 ICPE(ISPE)논문집 Vol.- No.-

A new SPWM control method for Uninterrupted Power System(UPS) is presented A triangle waveform is used as the reference signal The desired SPWM control signal can be obtained more easily with a group of comparators The output AC voltage can be regulated by controlling the lower reference and the upper reference of the comparators according to the feedback voltage Basic principle, an actual circuit and the experimental results on a 500W UPS for computer system is discussed as an example.<br/>

The role of roxadustat in chronic kidney disease patients complicated with anemia

( Jie Liu ),( Fan Yang ),( Yousuf Waheed ),( Shulin Li ),( Kun Liu ),( Xinglei Zhou ) 대한내과학회 2023 The Korean Journal of Internal Medicine Vol.38 No.2

The incidence of chronic kidney disease (CKD) is increasing worldwide and the current prevalence rate is 13.4%. There are > 120 million CKD patients in China and this number is expected to increase. One of the main abnormalities in patients with CKD and kidney impairment is decreased synthesis of erythropoietin (EPO), which causes anemia and affects iron metabolism. The probability of developing is higher in anemia patients with CKD than in the general population, and the incidence increases as kidney function decreases. Deficient EPO production by the kidney is the most important cause of renal anemia. Notably, anemia in patients with CKD has multiple causes, such as bleeding caused by platelet dysfunction, iron deficiency due to digestive and absorption disorders of the gastrointestinal tract, and shorter red blood cell life. Anemia is also a leading cause of hospitalization in patients with CKD. A new oral medication to treat renal anemia, the hypoxia-inducible factor prolyl hydroxylase inhibitor called roxadustat (FG-4592), regulates iron metabolism and promotes erythropoiesis. This drug has a therapeutic effect on patients with CKD. Roxadustat showed advantages over EPO in clinical experiments. This review summarizes the mechanisms of action, clinical applications, effectiveness, and safety of roxadustat.

A retrospective study on the efficacy of Roxadustat in peritoneal dialysis patients with erythropoietin hyporesponsiveness

Jie Liu,Shuang Li,Fan Yang,Tianyu Li,Rui Li,Yousuf Waheed,Chen Meng,Shulin Li,Kun Liu,Yanshan Tong,Haisheng Xu,Chuankuo Tian,Xinglei Zhou 대한내과학회 2024 The Korean Journal of Internal Medicine Vol.39 No.3

Background/Aims: Roxadustat, an oral medication for treating renal anemia, is a hypoxia-inducible factor prolyl hydroxylase inhibitor used for regulating iron metabolism and promoting erythropoiesis. To investigate the efficacy and safety of roxadustat in patients undergoing peritoneal dialysis (PD) with erythropoietin hyporesponsiveness. Methods: Single-center, retrospective study, 81 PD patients (with erythropoietin hyporesponsiveness) were divided into the roxadustat group (n = 61) and erythropoiesis-stimulating agents (ESAs) group (n = 20). Hemoglobin (Hb), total cholesterol, intact parathyroid hormone (iPTH), brain natriuretic peptide (BNP), related indicators of cardiac function and high-sensitivity C-reactive protein (hs-CRP) were collected. Additionally, adverse events were also recorded. The follow-up period was 16 weeks. Results: The two groups exhibited similar baseline demographic and clinical characteristics. At baseline, the roxadustat group had a mean Hb level of 89.8 ± 18.9 g/L, while the ESAs group had a mean Hb level of 95.2 ± 16.0 g/L. By week 16, the Hb levels had increased to 118 ± 19.8 g/L (p < 0.05) in the roxadustat group and 101 ± 19.3 g/L (p > 0.05) in the ESAs group. The efficacy of roxadustat in improving anemia was not influenced by baseline levels of hs-CRP and iPTH. Cholesterol was decreased in the roxadustat group without statin use. An increase in left ventricular ejection fraction and stabilization of BNP were observed in the roxadustat group. Conclusions: For PD patients with erythropoietin hyporesponsiveness, roxadustat can significantly improve renal anemia. The efficacy of roxadustat in improving renal anemia was not affected by baseline levels of hs-CRP0 and iPTH.

Molecular Cloning, Expression and Characterization of Bovine UQCC and Its Association with Body Measurement Traits

Liu, Yongfeng,Zan, Linsen,Zhao, Shuanping,Huang, Honggang,Li, Yong,Tang, Zhonglin,Yang, Shulin,Li, Kui Korean Society for Molecular and Cellular Biology 2010 Molecules and cells Vol.30 No.5

Ubiquinol-cytochrome c reductase complex chaperone (UQCC) involved in the development and maintenance of bone and cartilage is an important candidate gene for body measurement traits selection through marker-assisted selection (MAS). The expression of UQCC is upregulated in many human and animal models of height as well as other stature indexes. We have cloned the cDNA sequence coding UQCC gene in bovine. Genomic structural analysis indicated that bovine UQCC shares a high similarity with human UQCC. Furthermore, Real-Time PCR analysis showed that the expression of bovine UQCC is remarkably different in diverse tissues, including high level expression in the spleen, heart and windpipe, and relatively low expression in other tissues. We also analyzed allele frequencies in different cattle breeds and an association study on the selected SNPs. SNP DraI A2691T in intron 1 and SNP Bsh1236I A3150G in intron 8 are significantly associated with Body Length (BL), Rump Length (RL), Chest Depth (CD) and Pin Bone Width (PBW). For the A2691T SNP marker, there are significant effects on the RL (p = 0.0001), CD (p = 0.0059) and PBW (p < 0.0001) in 679 individuals; with A3150G SNP marker, there are significant effects on the BL (p = 0.0047) and CD (p = 0.0454). Regarding association analysis of combination of the two SNPs, there are significant effects on the BL (p = 0.0215), CD (p = 0.0282) and PBW (p = 0.0329) in the total population. The results suggest that the UQCC gene is a candidate gene of body measurement traits in bovine reproduction and breeding, and provide data for establishing an animal model using cattle to study big animal body type.

Molecular Cloning, Expression and Characterization of Bovine UQCC and Its Association with Body Measurement Traits

Yongfeng Liu,Linsen Zan,Shuanping Zhao,Honggang Huang,Yong Li,Zhonglin Tang,Shulin Yang,Kui Li 한국분자세포생물학회 2010 Molecules and cells Vol.30 No.5

Ubiquinol-cytochrome c reductase complex chaperone (UQCC) involved in the development and maintenance of bone and cartilage is an important candidate gene for body measurement traits selection through marker-assisted selection (MAS). The expression of UQCC is upregulated in many human and animal models of height as well as other stature indexes. We have cloned the cDNA sequence coding UQCC gene in bovine. Genomic structural analysis indicated that bovine UQCC shares a high similarity with human UQCC. Furthermore, Real-Time PCR analysis showed that the expression of bovine UQCC is remarkably different in diverse tissues, including high level expression in the spleen, heart and windpipe, and relatively low expression in other tissues. We also analyzed allele frequencies in different cattle breeds and an association study on the selected SNPs. SNP DraI A2691T in intron 1 and SNP Bsh1236I A3150G in intron 8 are significantly associated with Body Length (BL), Rump Length (RL), Chest Depth (CD) and Pin Bone Width (PBW). For the A2691T SNP marker, there are significant effects on the RL (p = 0.0001), CD (p = 0.0059) and PBW (p < 0.0001) in 679 individuals; with A3150G SNP marker, there are significant effects on the BL (p = 0.0047) and CD (p = 0.0454). Regarding association analysis of combination of the two SNPs, there are significant effects on the BL (p = 0.0215), CD (p = 0.0282) and PBW (p = 0.0329) in the total population. The results suggest that the UQCC gene is a candidate gene of body measurement traits in bovine reproduction and breeding, and provide data for establishing an animal model using cattle to study big animal body type.

The Analysis on the Influence of Risk Perception on Behavioral Intention of Cycling into Tibet

( Tao Song ),( Shulin Liu ) 아시아스포츠융합과학회 2020 Asia Pacific Journal of Applied Sport Sciences Vol.1 No.3

PURPOSE The purpose of this study is to establish a structural equation model of the influence of risk perception on satisfaction and behavioral intention of cycling into Tibet, and to verify the relationship between natural risk, social risk, cultural risk, organizational risk, satisfaction and behavioral intention. METHOD Taking cycling into Tibet as the background, people cycling into Tibet in the past three years were taken as the main research samples. A total of 380 questionnaires were collected online for research and analysis through the WJX questionnaire network platform. Descriptive statistics, exploratory factor analysis, confirmatory factor analysis and structural equation model were used to analyze the collected data. RESULT The results showed that (1) cyclists cycling into Tibet were engaged in serious leisure and their natural risk perception positively affected their behavioral intentions. (2) satisfaction was an important predictor of their behavioral intentions cycling into Tibet. (3) social, cultural and organizational risk negatively affected satisfaction. CONCLUSION Satisfaction is an important factor in the behavior intention of cycling into Tibet. The results of this study provided some practical suggestions for the organization and management of cycling into Tibet, as well as suggestions for future studies, such as theoretical supports for tourists' behavioral intentions like revisiting Tibet.

Numerical analysis of the dynamic behavior of a rotor-bearing-brush seal system with bristle interference

Yuan Wei,Shulin Liu 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.8

To minimize leakage and maintain the efficiency of turbomachinery, brush seal can be installed with zero clearance or interference as the flexibility. This leads to contact between the rotor and bristle pack, and may cause self-excited vibration, even instability. In this study, to establishment a mathematical model of the rotor system, a seal force model with bristle interference is proposed and the nonlinear oilfilm force is applied in view of short bearing assumption. The influences of main factors containing rotor rotational speed, installing interval, disc mass, and disk eccentricity on the nonlinear characteristics of the rotor-bearing-brush seal system are conducted by adopting bifurcation diagram, spectrum cascade, axis orbit, and Poincaré map. The results indicate that the vibration amplitude of the system with bristle interference is a bit larger than that without interference. The system stability is enhanced with smaller disk mass at a higher rotational speed. The proposed model could provide valuable reference for the design of a rotor-bearing-seal system.

An Improved Defect Detection Algorithm of Jean Fabric Based on Optimized Gabor Filter

Shuangbao Ma,Wen Liu,Changli You,Shulin Jia,Yurong Wu 한국정보처리학회 2020 Journal of information processing systems Vol.16 No.5

Aiming at the defect detection quality of denim fabric, this paper designs an improved algorithm based on theoptimized Gabor filter. Firstly, we propose an improved defect detection algorithm of jean fabric based on themaximum two-dimensional image entropy and the loss evaluation function. Secondly, 24 Gabor filter bankswith 4 scales and 6 directions are created and the optimal filter is selected from the filter banks by the onedimensionalimage entropy algorithm and the two-dimensional image entropy algorithm respectively. Thirdly,these two optimized Gabor filters are compared to realize the common defect detection of denim fabric, suchas normal texture, miss of weft, hole and oil stain. The results show that the improved algorithm has betterdetection effect on common defects of denim fabrics and the average detection rate is more than 91.25%.

Effect of Chito-oligosaccharide Supplementation on Immunity in Broiler Chickens

Deng, Xingzhao,Li, Xiaojing,Liu, Pai,Yuan, Shulin,Zang, Jianjun,Li, Songyu,Piao, Xiangshu Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.11

This study was conducted to determine the effects of dietary supplementation of either 100 mg/kg chito-oligosaccharide (COS) or chlortetracycline (CTC) with corn-soybean-fish meal on immunity in broiler chickens. A total of 147 one-day old male broiler chicks were randomly allocated to 3 treatments with 7 replicate pens per treatment and 7 birds per pen. The experimental diets consisted of a control diet based on corn, soybean and fish meal without COS and any antibiotic supplement and similar diets supplemented with either CTC (80 mg/kg from d 1 to 21 and 50 mg/kg from d 22 to 42) or COS (100 mg/kg from d 1 to 42). During the entire experimental period, all birds had ad libitum access to diets and water. The main immune organ indices, T-lymphocyte proliferation, serum cytokine concentrations, serum NO level and serum iNOS activity were measured on d 21 and d 42. On d 21, broilers fed 100 mg/kg COS had improved (p<0.01) indices of spleen, thymus, and bursa of Fabricius compared with the control and CTC birds. Birds receiving 100 mg/kg COS had higher (p<0.05) serum concentrations of $IL-1{\beta}$, IL-6, IgM, NO and iNOS than birds on the control treatment. Serum $Ca^{2+}$ level of birds fed 100 mg/kg COS tended to be higher (p = 0.049) than in birds fed CTC. On d 42, the birds fed 100 mg/kg COS had higher (p<0.05) concentrations of TNF-${\alpha}$ and IgM in serum than birds in both the CTC and control treatments. Birds fed 100 mg/kg COS had a higher concentration of IFN-$\gamma$ than the control group. In conclusion, dietary supplementation of COS appeared to improve the immunity of broilers by promoting the weight of the main immune organs, increasing IgM secretion, stimulating microphages to release $TNF-{\alpha}$, $IL-1{\beta}$, IL-6 and IFN-$\gamma$, and activating iNOS to induce NO.