韓國産 景天科 植物에 關한 本草學的 考察

朴柱性,新民敎,宋昊埈 圓光大學校 韓醫學硏究所 1994 원광한의학 Vol.4 No.1

For the purpose of developing Korean Herbalogy with the plants of Crassulacea which grow wild and is planted in Korea, the these and writings in hirbalogy, from literature of successive generations, have been throughly investigative and the results obtained were as follows; 1. There were totaled to 9 genera and 55 species in Korea and among them medicinal plants are 5 genera, 17species. Some 31% in total but the number of species may be added because of the similiar plants. 2. According to sum of 55 species in Crassulacea family, they were classified into Sekum genera 33, Orastachys 8, Rhodiola genera 4, Bryophyllum genera 3 etc. 3. According to the oriental names which can be used for medical purpose, the medicinal plants belonging to the Crassulacea family were classified as Herba 10, Radix 4, Folium 3, Flos 1. Thus it was noticed that Herba was the main kind. 4. According to nature of medicinal plants, they were classified into cold, cool, 6: balance, 3 ; warmth, 1. Thus it was noticed that cold, cool is the main in nature of medicinal plants. 5. According to properties and principal curative action, they were classified into drugs to remove dramatic swelling 9 drugs for hemostatis 7, to remove toxic heat with febri fugal and detoxicant drugs 6. From this result, it was revealed that the plants for medical purpose in Crassulacea was 31% of the whole, in which Herba was mostly abundunt. It is considered that many experiments and clinical apporaches must be continued to use Crassulacea plants widely.

大學 敎養敎育 改善을 위한 基礎 調査硏究 : 仁荷大學校 學生을 對象으로

朴州信 仁荷大學校 學生生活硏究所 1993 學生生活硏究 Vol.13 No.-

상호상관 함수를 이용한 지중선로 고장점 추정

朴星完,林泳範,鄭州桓,成洛煥,金喆煥,申明徹 成均館大學校 科學技術硏究所 1994 論文集 Vol.45 No.2

This paper is intended as an investigation of fault location for underground line. Over the past few decades a considerable number of studies have been made on protection of underground line. However, these approaches require the interruption of electric power supply from source for fault location estimation. Therefore, we proposed fault location algorithm for underground line protection without interruption of electric power supply. Cross correlation function is used in this algorithm. Also, EMTP data is used to demonstrate the capability of the proposed fault location algorithm.

大學生의 政治意識에 관한 調査硏究 : 仁荷大學生을 中心으로

朴州信 仁荷大學校 學生生活硏究所 1991 學生生活硏究 Vol.11 No.-

치아 우식증의 조기 진단을 위한 QLF-D 개발

박형주,김종수,유승훈,신지선 大韓小兒齒科學會 2011 大韓小兒齒科學會誌 Vol.38 No.4

QLF-D system composed with DSLR(digital single-lens reflex) camera, and the images of natural enamel caries and artificial caries was developed from 2 days to 14 days captured by QLF-D system. The correlation between lesion depth of the polarized microscope and luminosity ratio of QLF-D image was analyzed and the results were summarized as follows: 1. The Pearson correlation value between the lesion depth of polarized microscope images and luminosity ratio of QLF-D images was 0.969(p<0.01). 2. From Regression analysis of lesion depth from polarized image by demineralized period, the equation was y = 8.67x - 1.16(p<0.05). 3. From Regression analysis of luminosity ratio from QLF-D image by demineralized period, the equation was y = 3.53x + 6.42(p<0.05). From the results, QLF-D system can detect the enamel caries at the very early stage and can monitor the progression of demineralization and remineralization. For the convenient use of QLF-D system in the laboratory, the image analysing software was needed to analyze of interest site of enamel caries lesion. 저자는 DSLR(digital single-lens reflex) 카메라를 이용한 QLF-D 시스템을 고안하여, 사람의 유구치에 자연 발생된 법 랑질 초기 우식증을 관찰하고, 유구치 법랑질 시편을 대상으로 2일부터 14일까지 인공 탈회시킨 후 탈회 기간에 따른 상관관 계를 편광 현미경 소견과 비교 분석한 결과 다음과 같은 결과를 얻었다. 1. 탈회 기간에 따른 편광 현미경 상의 병소 깊이와 QLF-D 영상의 광밀도 값 비율 간의 피어슨 상관 계수는 0.969였다 (p<0.01). 2. 편광현미경에서 측정된 병소 깊이의 탈회 기간에 대한 회귀분석 결과 y=8.67x-1.16의 회귀 방정식이 산출되었다 (p<0.05). 3. QLF-D 영상에서 측정된 광도값 비율의 탈회 기간에 대한 회귀분석 결과 y=3.53x+6.42의 회귀 방정식이 산출되었다 (p<0.05).

국내에서 생산 판매되는 담배 각초에 존재하는 알칼로이드 함량과 주류연의 연기성분 비교 연구

박병주,신주식,임흥빈 충북대학교 연초연구소 2006 煙草硏究 Vol.20 No.-

국내에서 시판되고 있는 69종의 궐련담배 각초를 재료로 하여 궐련담배 각초에 함유되어 있는 alkaloid 함량을 측정하고 궐련담배 주류연의 tar 및 nicotine 함량을 측정하여 비교분석한 결과는 다음과 같다. 1. 국내에서 시판되고 있는 귈련담배는 tar와 nicotine의 함량이 각각 5 mg, 0.5 mg 수준인 담배가 가장 많았다. 2. 국내에서 시판되는 궐련담배 각초 alkaloid 성분의 평균함량은 nicotine 15.7±1.8 mg/g, nornicotine 432±182 μg/g, anabasine 63±28 μg/g, myosmine 52±17 μg/g이었다. 3. Alkaloid 성분 중 nornicotine 함량은 타사 제품에 비해 A사와 군소업체 제품담배에서 유의하게 높았다. 4. 국내에서 시판되는 궐련담배 각초에 존재하는 nicotine의 주류연으로의 이행율은 10 % 이하였다. This study was carried out to compare alkaloids contents existed in tobacco shred, with major components in tobacco smoke from 69 cigarette brands being on sale in Korea. Alkaloids and cigarette smoke components were analysed by gas chromatography. Cigarette brands with the level of tar 5 mg/cig and nicotine 0.5 mg/cig in mainstream smoke were major in Korea. Mean values of nicotine, nornicotine, anabasine, and myosmine contents existed in tobacco shred from 69 cigarette brand were 15.6 ± 1.9 mg/g, 431 ± 187 ug/g, 62 ± 28 ug/g, 53 ± 16 ug/g, respectively. Nornicotine contents existed in tobacco shred of cigarette brands manufactured by A company and some small companies were relatively higher than that other three major companies. Direct transfer rates of nicotine from shred to mainstream smoke in most cigarette being on sale in Korea was lower than 10%. These results indicates that alkaloids contents in tobacco shred from cigarette have something to do with cigarette smoke components and this analysis have to fulfil periodically in order to obtain a basic information for quality evaluation of cigarette smoke in connection with smoking and healths.

2-Halobenzyl Phenyl Ether의 제조와 그 광화학

박용태,서주수,김영희,신현일 진주산업대학교 1996 論文集 Vol.35 No.-

The photochemical reaction of 2-halobenzyl phenyl ethers was studied. In order to study the photoreactivity of haloarene tethered to arene with alkyl ether group, two 2-halobenzyl phenyl ethers were prepared. when the acetonitrile solution of 2-halobenzyl ethers in pyrex immersion vessel was irrdiated by 100W medium pressure Hg-lamp, the Photo-Fires type products, o(2-halo)benzyl phenol and p-(2-halo)benzyl phenol were obtained. Photo-Fires type reaction of 2-halobenzyl phenyl ether ws supposedly due to rearrangement of 2-halobenzyl radical and phenol radical produced by C_sp3-O bond cleavage. However when the reaction was carried out in benzene/aqueous alkalic solution with vycor immersion vessel, photocyclized product along the Photo-Fries type reaction products and photoreduced product was observed.

大學生의 職業觀에 관한 調査硏究 : 仁荷大學生을 中心으로

朴州信 仁荷大學校 學生生活硏究所 1988 學生生活硏究 Vol.9 No.-

1988學年度 新入生 實態調査

朴州信,李相蘭 仁荷大學校 學生生活硏究所 1988 學生生活硏究 Vol.9 No.-

Gymnemic acid의 간장 및 신장의 조직에 미치는 영향에 대한 실험적 연구

박순록,신인철,강주섭,서대규 漢陽大學校 環境科學硏究所 1994 環境科學論文集 Vol.15 No.-

생체에 투여된 물질은 생체내에서 아무 변화없이 체외로 배설되는 경우도 있지만, 대부분은 체내에서 여러가지 생화학적 변화를 거쳐 배설된다. 이런 체내에서의 생화학적 변화는 주로 간장에서 일어나고, 이런 물질과 그 대산사물의 배설은 주로 신장에서 이루어지며, 일부는 다른 경로를 통하기도 한다. 그러므로, 약물의 대사 및 배설장기인 간장과 신장에 이런 물질이 축적되면 그 장기가 손상되는 악순환을 거치게 된다. 이에, 본 실험은 2000여년 전부터 오늘에 이르기까지도 인도지방에서 비만이나 당뇨병에 대한 민간요법제로 이용되어 온 Gymnema sylvestre 잎의 유효성분인 gymnemic acid의 신장과 간장의 조직에 미치는 영향을 검토하고자 실시하였다. 실험동물은 정상 Wistar계 웅성 흰쥐(체중 200gm 내외)를 사용하였고, 실험기간중에 먹이와 물은 자유로이 공급하였다. 실험군은 정상대조군과 동일한 조건하에서 15일동안 gymnema산을 각각 500㎎/㎏, 800㎎/㎏의 용량으로 하루 3회, 즉 오전 7시, 오후 2시, 오후 7시에 각각 경구투여하고, gymnema산 투여 15일째 24시간동안 절식시킨 후 경동맥사혈로 희생시킨 다음 개복하여 간우측 전엽과 우측 신장을 적출하여 일반 육안적 소견과 Hematoxylin 및 eosin 이중염색상의 광학 현미경적 소견을 관찰하여 다음과 같은 결과를 얻었다. 1. 흰쥐 신장의 육안적 소견과 Hematoxylin 및 eosin 이중염색 소견에서는 정상 대조군과 GA투여군에서 특기할 만한 소견이 관찰되지 않았다.(Fig 1-a, 1-b, 1-c). 2. GA(500㎎/㎏)투여군 흰쥐 간장에서 Hematoxylin 및 eosin 이중염색 소견상 간소엽의 중심대와 일부 중간대에서 동양혈관이 확장되었고, 간세포대의 배열이 불규칙해졌으며, 간세포내의 간세포배열이 불규칙해졌고, 공포변성이 초래된 간세포도 관찰도었다(Fig. 3-a,3-b). 3. GA(800㎎/㎏) 투여군 흰쥐 간장에서 Hematoxylin 및 eosin 이중염색 소견상 간소염 전반에 걸쳐 동양혈관이 확장되었고, 간세포대배열이 불규칙해졌으며, 간세포대내의 간세포 배열이 불규칙해졌고, 공포변성이 초래된 간세포도 관찰되었다(Fig. 4-a, 4-b). The majority of the chemicals that enter a living system is taken to elimination by hepatic biotransformation and renal excretion of its metabolites and unchanged form. But, some chemicals are also excreted into feces or through other routes. Therefore, the accumulation of the chemicals in the liver and kidney have damaged the organs. It was more than 3000 yours ago that Gymnema sylvestre. Asclepaidaceae piant indegenous to certain regionss of the tropical and subtropical countries, began to be used a popular folk medicine among native population in India in order to treat obesity and "Madhumeha(DM)" and its use still continues to today in India. Theorefore, this study has the purpose to investigate the effect of gymnemic acid(GA) Which is an effective ingredient of Gymnema sylvestre on the liver and the kidney. In the study, Wistar albino male rats weighing around 200gm were divided into three groups, basic diet group(control), GA(500㎎/㎏)group, GA(800㎎/㎏)group, and administered orally the gymnemic acid for 15 days in dose of 500㎎ and 800㎎ per ㎏ of body weight triple a day. All animals were sacrificed at 15 days after the daministration of gymnemic acid and starved for 24 hours sacrificing them, the specimens and eosin. The specimens have been examined grossly and light microscopically. The results were as follows. 1. In the gross and light microscopic observations of the kidney, the control and all experimental groups were not observed pathologic findings. 2. The gross observations of the liver of the of the control and all experimental groups wrer not observed pathologic findings. 3. The sinusoidal dilation, hepatic cord irregularity and disarrangement of hepatocyte were observed in the central zone and a part of intermediate zone of the hepatic lobule of the 15 days GA(500㎎/㎏) administered group. 4. The sinusoidal dilatation, hepatic cord irregularity, disarrangement of hepatocyte and abnormal shaped hepatocytes were observed in all zonesof the hepatic lobule of the 15 days GA(800㎎/㎏) administered gruop. Consequently, it is suggested that administration of large dose of gymnemic acid in the normal rats induces hepatic cellular damages.