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- 검색키워드
- 저자 : Seam, Rajeev K. (검색결과 31 건)
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Noh, Seam,Kim, Jihee,Hur, Jin,Hong, Yongseok,Han, Seunghee Springer-Verlag 2018 Environmental science and pollution research inter Vol.25 No.7
<P>The monomethylmercury (MMHg) concentrations, water quality parameters (e.g., pH, suspended particles, total phosphorus, sulfate, and chlorophyll-a), and compositions of dissolved organic matter (DOM) were analyzed to understand how the quality of DOM is related to the MMHg distributions in the surface waters of 14 reservoirs. The excitation-emission matrix (EEM) fluorescence spectroscopy identified six fluorescence peaks, and a parallel factor analysis (PARAFAC) of EEM spectra identified three components of DOM: microbial humic-like (C1), terrestrial humic-like (C2), and protein-like DOM (C3). Using the observation data, the principal component analysis (PCA) were carried out to understand the relative importance of the fluorescence properties of DOM, representing DOM quality, on the MMHg distribution. The loading plot of PCA showed a strong positive correlation between the MMHg and protein regions of the EEM spectra and no correlation between MMHg and the terrestrial humic regions of the EEM, suggesting that autochthonous DOM production is a key factor in increasing MMHg concentration in reservoir water. The preliminary mass flux estimation, which was carried out to identify the major sources of MMHg in Okjeong reservoir, revealed that the major sources are sediment diffusion and water column methylation. Because the studied reservoirs are located remotely from a large-sized river and industrial region, most MMHg in reservoir water is likely diffused from the surface sediment or produced in the water column, and these sources tend to increase in reservoirs enriched with autochthonous DOM. It is suggested that EEM fluorescence can improve our ability to trace the major sources of MMHg in diverse reservoirs.</P>
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( Chan Seam Gil ),( Moon Sik Jang ),( Seok Hyun Eom ) 한국미생물생명공학회(구 한국산업미생물학회) 2017 Journal of microbiology and biotechnology Vol.27 No.8
The bioactivities of boxthron fruits, a source of oriental medicine, are well known, whereas phytochemical studies of the boxthorn stem are rare. In this study, the stem extract of boxthorn (Lycium chinense Miller) and its subfractions were evaluated for their effects on nitric oxide (NO) inhibition and procollagen type I peptide (PIP) synthesis. A phenolic amide isolated from the stem extract was also assayed for these effects. The compound, N-trans-feruloyltyramine, was identified by <sup>1</sup>H, <sup>13</sup>C, and 2D-nuclear magnetic resonance analyses. In NO inhibition, the chloroform fraction (CF) exhibited the strongest inhibitory activity (MIC<sub>50</sub> = 24.69 μg/ml) among the subfractions of the ethanol extract (EE). N-transferuloyltyramine isolated from the CF showed strong NO inhibitory activity, presenting with an MIC<sub>50</sub> of 31.36 μg/ml. The EE, CF, and N-trans-feruloyltyramine shown to have NO inhibition activity were assayed for the activity of PIP synthesis. The EE and CF showed relatively high PIP values of 38.8% and 24.21% at 100 μg/ml, respectively. The PIP value for 20 μg/ml N-trans-feruloyltyramine showed a 36% increase compared with the non-treated control, whereas that treated with 20 μg/ml ascorbic acid as a positive control showed a 13% increase. The results suggest that the proper stem extract of boxthorn stem could be efficiently used to produce good cosmetic effects.
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Noh, Seam,Kim, Chan-Kook,Kim, Younghee,Lee, Jong-Hyeon,Han, Seunghee Elsevier 2017 Science of the Total Environment Vol.580 No.-
<P><B>Abstract</B></P> <P>We investigated monomethylmercury (MMHg) concentrations in 448 samples of four common fish species (barbel steed, largemouth bass, leopard mandarin, and bluegill) and the trophic states of 14 artificial reservoirs in South Korea in order to understand how trophic states of reserviors affect MMHg concentrations in fish. The trophic state index (TSI) of each reservoir was determined using empirical equations based on the monthly chlorophyll-a, total phosphorus, and Secchi depth, collected over a three-year period. The length-normalized MMHg concentrations in fish showed a negative correlation with the TSI based on chlorophyll-a (r<SUP>2</SUP> =0.90) and total phosphorus (r<SUP>2</SUP> =0.75) that may be a result of particle dilution of MMHg in surface waters. This study revealed that MMHg accumulation in fish was better correlated with TSI than MMHg in water, therefore, we suggest that the measurement of TSI based on chlorophyll-a and total phosphorus is an effective way to predict MMHg bioaccumulation across diverse reservoirs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Fish MMHg showed a negative correlation with lake trophic state index. </LI> <LI> It might be a result of particle dilution of MMHg at the base of food chains. </LI> <LI> Measuring trophic state is a practical tool to predict MMHg bioaccumulation. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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현대외식공간에 적용된 전통 이미지 표현 방법 사례 연구
이샘(Lee, Seam),신선하(Shin, Sun-Ha),유예나(Yoo, Ye-Na),안세윤(An, Se-Yun) 한국실내디자인학회 2015 한국실내디자인학회 학술대회논문집 Vol.2015 No.5
There is a growing trend to use tradition elements such as traditional Korean cuisine and culture as major items. in the restaurant industry of large companies. This study aims to investigate the cases of expression method which traditional images are applied to the modern restaurant spaces. We only focus on the authentic Korean food brands among the Korean buffet restaurant franchises which are run from 2013. The designs of restaurant spaces are classified into space elements and sensitive elements to analyze the expression method of the traditional images. The purpose of this study is to show a guideline for the future plans to use traditional images in modern restaurant space and lay the groundwork for making a effective plan in spatial composition. It would broaden the scope of the study to other franchises and commercial space. It is expected that in the study of further research on the traditional image of commercial space have been applied.
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Fotedar, Vikas,Seam, Rajeev K.,Gupta, Manoj K.,Gupta, Manish,Vats, Siddharth,Verma, Sunita Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1
Background: Breast cancer is an increasing health problem in India. Screening for early detection should lead to a reduction in mortality from the disease. It is known that motivation by nurses influences uptake of screening methods by women. This study aimed to investigate knowledge of breast cancer risk factors & early detection methods and the practice of screening among nurses in Indira Gandhi Medical College, Shimla, Himachal Pradesh. Materials and Methods: A cross-sectional study was conducted using a self-administered questionnaire to assess the knowledge of breast cancer risk factors, early detection methods and practice of screening methods among 457 nurses working in a Indira Gandhi Medical College, Shimla-H.P. Chi square test, Data was analysed using SPSS version 16. Test of significance used was chi square test. Results: The response rate of the study was 94.9%. The average knowledge of risk factors about breast cancer of the entire population is 49%. 10.5% of nurses had poor knowledge, 25.2% of the nurses had good knowledge, 45% had very good knowledge and 16.3% of the nurses had excellent knowledge about risk factors of breast cancer and early detection methods. The knowledge level was significantly higher among BSC nurses than nurses with Diploma. 54% of participants in this study reportedly practice BSE at least once every year. Less than one-third reported that they had CBE within the past one year. 7% ever had mammogram before this study. Conclusions: Results from this study suggest the frequent continuing medical education programmes on breast cancer at institutional level is desirable.
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Thakur, Priyanka,Seam, Rajeev Kumar,Gupta, Manoj Kumar,Rastogi, Madhup,Gupta, Manish,Bhattacharyya, Tapesh,Sharma, Mukesh,Revannasiddaiah, Swaroop Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.10
Purpose: Blood hemoglobin levels are known to influence response to radiotherapy. This retrospective analysis compared the effect of hemoglobin levels upon response to radiation among patients treated with radiation alone (by accelerated hyperfractionated radiotherapy) versus those treated with concurrent cisplatin chemoradiotherapy. Materials and Methods: Among patients treated for locally advanced carcinoma of the cervix (LACC) during 2009-10, a total of 60 fulfilled the eligibility criteria. In this time frame, external beam radiotherapy was delivered with either concurrent chemoradiotherapy (CRT, n=31) (45Gy over 25 fractions, with weekly cisplatin at 40mg/m2), or with accelerated hyperfractionated radiotherapy (AHRT, n=29) (20Gy over 10 daily fractions over the first two weeks, followed by 30Gy over 20 fractions over the next two weeks, with two fractions of 1.5Gy per day, without the use of chemotherapy). Mean weekly hemoglobin (MWH) levels of all patients were calculated as the arithmetic means of weekly recorded blood hemoglobin levels. As per MWH, patients in both of the AHRT or the CRT groups were classified into two subgroups-those with MWH between 10-10.9g/dL, or with MWH>11g/dL. Complete response (CR) to external beam RT phase (prior to brachytherapy) was declared after clinical examinations and computed tomography. The CR rate was noted for both MWH sub-groups within each of the AHRT and CRT groups. Results: Within the AHRT group, patients with MWH>11g/dL had a much better CR rate in comparison to those with MWH:10-10.9g/dL (80% vs. 21.1%) which was statistically significant (p 0.0045). Within the CRT group, there was no significant difference in the outcomes within the MWH>11g/dL and MWH:10-10.9g/dL sub-groups (CR rates of 80% vs. 61.9%, p=0.4285). Conclusions: The importance of maintaining a minimum hemoglobin level of 11g/dL during RT is much greater for patients treated with RT alone, than for patients treated with concurrent chemoradiotherapy. Enhanced haemoglobin levels during RT may to an extent negate the ill-effects that may otherwise arise due to non-use of concurrent chemotherapy.
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Bioconcentration of methylmercury in microzooplankton in a temperate river
Kim, Hyunji,Noh, Seam,Kim, Eunhee,Poopal, Rama Krishnan,Lee, Hak Young,Han, Seunghee Wiley (John WileySons) 2011 Environmental toxicology and chemistry Vol.30 No.12
<P>To understand the bioconcentration of methylmercury (MeHg) at the base of the riverine food chain, we determined levels of dissolved organic carbon, microseston, Hg, and MeHg in surface water in relation to the microzooplankton MeHg from Yeongsan River. The spatial distribution of unfiltered Hg (0.29-3.1 ng/L) and dissolved Hg (0.15-0.74 ng/L) closely followed the microseston distribution. The spatial distribution of unfiltered MeHg (0.0078-0.077 ng/L) and dissolved MeHg (0.0069-0.018 ng/L) increased with increasing distance from the river mouth and appeared to arise from the shallow wetlands surrounding the upper riverbanks and then to be transported downstream. The logarithm of the MeHg bioconcentration factor for microzooplankton ranged from 5.3 to 6.0 (5.7 0.18), and for microseston ranged from 4.0 to 5.4 (4.9 0.35). Linear correlation statistics comparing microzooplankton MeHg and river water characteristics revealed that microzooplankton MeHg concentration was most significantly correlated with unfiltered MeHg (r = 0.83) and particulate MeHg (r = 0.80) levels. This result suggests that MeHg in unfiltered river water, which is relatively easy to determine, can be used as a surrogate for MeHg in microzooplankton that may influence MeHg levels in higher-trophic-level organisms.</P>
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응급실에 내원한 발열 환자에서 암 진단 유무에 따른 임상증상의 중증도에 대한 후향적 조사 연구
이은샘,강푸름,신유경,설근희,Eun Seam Lee,Purum Kang,You Kyoung Shin,Geun Hee Seol 한국기초간호학회 2023 Journal of korean biological nursing science Vol.25 No.2
Purpose: This study aimed to understand the general characteristics and biomarkers of inflammation in adult patients who visited the emergency department with fever and to determine whether the severity of clinical symptoms varies according to cancer diagnosis. Methods: Data were collected retrospectively from 4,002 adult patients with fever who visited the emergency department at a tertiary hospital from January 2018 to December 2018 using medical records. Results: On average, cancer patients were older than non-cancer patients (p < .001), and differences were observed between cancer and non-cancer patients in the origin of fever and biomarkers associated with inflammation. A higher proportion of cancer patients than non-cancer patients had a Korean Triage and Acuity Scale level of 1 to 3 (p < .001), and more cancer patients than non-cancer patients met two or more criteria for systemic inflammatory response syndrome (p = .001). More life-saving interventions in the emergency department were required in cancer patients than in non-cancer patients (p < .001), and cancer patients spent more time in the emergency department than non-cancer patients (p < .001). Conclusion: This study showed that the general characteristics and biomarkers of inflammation differed among adult patients with fever depending on cancer diagnosis. Furthermore, among adult patients with fever, cancer patients had more severe clinical symptoms than non-cancer patients. The results of this study are hoped to be helpful as a basis of nursing knowledge for adult patients with fever in the emergency department and as evidence for the classification of severity in patients with fever according to cancer diagnosis.
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경구노출을 통한 어린이용품 중 중금속류 노출 및 위해성 평가
심기태 ( Ki-tae Sim ),노샘 ( Seam Noh ),송기봉 ( Ki-bong Song ),김일규 ( Il-gyu Kim ),석광설 ( Kwang-seol Seok ),김동훈 ( Dong-hoon Kim ) 한국환경분석학회 2017 환경분석과 독성보건 Vol.20 No.2
In this study, we evaluate the levels of 6 heavy metals (barium, cadmium, chromium, copper, lead, and nickel) in domestically distributed children`s products. We particularly focus on estimating the risk of oral exposure caused by the sucking behavior of 6-month and older infants. Our research shows that the levels of cadmium and lead in paint-coated toy products, relative accessories, and picture books exceeds domestic safety standards. Concentration of cadmium and lead is highest in the case of paint-coated toy products and accessories. The highest concentrations of cadmium, chromium, copper, and lead are observed in clay toys as the result of transferred amount due to the sucking action. Risk evaluation of direct ingestion of heavy metals shows the possibility of adverse effects caused by cadmium, lead, and nickel in accessories. In case of nondiets, the risk of oral toxicity was evaluated as being hazardous from cadmium and copper in clay toys. On comparing domestic and overseas regulatory standards, it was found that some substances exceeded the recommended standards. Most of these products are unauthorized products and their production must be regulated. This study can be used to reference data for prevention of child health hazards through the assessment of potential hazard level of heavy metals in child products.
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