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16주간의 자전춤 참여가 중년비만고혈압여성의 관상동맥위험인자에 미치는 영향
곽정자(Kwak Jung-Ja),김종경(Kim Jong-Kyung),최현민(Choi Hyun-Min),노호성(Nho Ho-Sung) 한국체육과학회 2008 한국체육과학회지 Vol.17 No.2
It is generally known that cardiovascular and metabolic diseases such as hypertension, diabetes, hyperlipidemia increase morbidity and mortality in postmenopausal women. This study investigated the effects of Jajun-Dance to coronary heart disease of middle age women with hypertension. Thirteen sedentary women (55.8±5.2 yrs) were recruited for this study, and completed 16 weeks of Jajun-Dance program. All subjects were diagnosed as essential hypertension patients. Blood-sugar level (FBG), total cholesterol (TC), triglyceride (TG), systolic blood pressure (SBP), diastolic blood pressure (DBP) and visceral fat area (VFA) were measured. The Jajun-Dance program included 10 minutes warm up (exercise for flexibility), 40 minutes Jajun-Dance, and 10 minutes cool down. The subjects participated in Jajun-Dance program three times a week. Exercise was maintained at exercise intensity corresponding to rating of perceived exertion (RPE) 13-15. The results showed that FBG, SBP, and DBP (6.0 ㎜Hg) were significantly decreased after Jajun-Dance program. TG and VFA tended to decrease, but there were no significant differences. This study suggests that hypertensive middle-aged women could modify coronary risk factors with regular exercise, and that the aerobic Jajun-Dance program could effectively reduce high blood pressure.
주용진,최성문,최영자,성호석 ( Yoing Jin Joo,Sung Moon Choi,Young Ja Choi,Ho Suk Sung ) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.5
A Case of Ehlers-Danlos syndrome Yoing Jin Joo, M.D., Sung Moon Choi, M.D., Young Ja Choi*, M.D., Ho Suk Sung, M.D. Department of Dermatology, Clooego of Medicine, Inje University, Pusan, Korea We presented a case of Ehlers-Danlos syndrome in a 25-year old female, who had hyperextensibility of skin, skin fragility, cigarette paper-like atrophic scar, joint hyperextensibility and skeletal abnormality of scoliosis since birth. There was no family history. Microscopic and electron microscopic examinations of the skin biopsy specimens from normal appearing skin on the forearm and the site of subcutaneous nodule was compatible with finding of Ehlers-Danlos syndrome. Although the manifestations of this case including marked extensibility of skin, joint, skin fraility and atrophic scar might be in accord with type Ⅰ(gravis) Ehlers-Danlos syndrome, skeletal abnormality of scoliosis did not correspond to this type, but to type Ⅳ(hydroxylysine deficient) Ehlers-Danlos syndrome. We consider this case as a type Ⅳ Ehlers-Danlos syndrome.
강은실(Kang Eun-Sil),김숙자(Kim Sook-Ja),강성년(Kang Sung-Nyun),최성은(Choi Sung-Eun) 고신대학교 전인간호과학연구소 2008 전인간호과학학술지 Vol.3 No.-
The purpose of this study was to describe the spiritual well-being of nursing students to provide a basic data for the development the curriculum of Spiritual Nursing Care in nursing collages. The subjects for this study were consist of 58 nursing students in K University of Pusan city in Korea. All of them were educated about Spiritual Nursing Care for 100 minutes in a week, during totally 8 weeks in one semester. The data were collected during 7days from July 11 to July 18,2004 by using structured questionnaire method. The measurement of the spiritual well-being was performed with 6 points-index which is composed of 21 items and is modified by Sang-Soon Choi(1990)from Palau tzian & Ellison(1983) s. Its high score means that the degree of spiritual well-being of the subject is high. The data were analyzed by using the SPSS WIN 10.1 program according to the purpose of this study. The general characteristics of the subjects were analyzed by calculating the real quantity and the percentage, and the spiritual well-being scores were identified through calculating the mean value of individual domain. The significant difference of the general characteristics with the spiritual well-being was analyzed by t-test and ANOVA, Scheffe s test. The results of this study were as follow; 1.The spiritual well-being of the subjects The average value for the spiritual well-being of the subjects was 97.78(SD=±10.53) among the possible ranges of 21-126. The mean value of all items was 4.66(SD=±0.502) and high relatively. 2. The spiritual well-being according to general characteristics of subjects The analysis of the spiritual well-being according to general characteristics of the subjects showed statistically significant difference on the degree of life satisfaction in faith(F=4.327, P= .004),the degree of recognition about God s initiation in their daily life(F=3.933, P= .013),the degree of satisfaction about Nursing as their major(F=6.608, P= .000), their assurance of salvation(t=4.557,P= .037). among the personal religious actions, praising(F=3.32,p= .017), The group of nursing students responded that they were satisfied in their faith life, always God has the initiative in their daily lives personally, they were satisfied about Nursing as their major very much, and they have their assurance of salvation showed the highest degree of the spiritual well-being than any other group. In conclusion, in this study we observed that the spiritual well-being of nursing students was high relatively. The general characteristics of subjects were related to the spiritual well-being of them were the degree of satisfaction in their faith lives,their recognition about God s initiation in their daily life, their satisfaction about Nursing as their major, among the personal religious actions, regular praising and their assurance of salvation. Therefore this study s results can be used for developing a spiritual nursing education and program to strengthen nursing student s spirituality to practice in spiritual nursing care.
Choi, Ji Eun,Bae, Jun Sang,Kang, Myoung Jae,Chung, Myoung Ja,Jang, Kyu Yun,Park, Ho Sung,Moon, Woo Sung NATIONAL HELLENIC RESEARCH FOUNDATION 2017 ONCOLOGY REPORTS Vol.38 No.3
<P>Epithelial-mesenchymal transition (EMT) is known to be associated with cancer progression, metastatic spread, and therapeutic resistance and to occur at the invasive front. Cancer stem cells (CSCs) display stemness features and might be implicated in tumor initiation, local recurrence and metastasis. The present study was conducted to examine the expression status and relationships between EMT-and CSC-related proteins in the different tumor areas of primary colorectal cancer (CRC), along with their clinicopathological significance. We performed immunohistochemical staining for 4 EMT-related proteins, namely E-cadherin, beta-catenin, snail and vimentin, and two CSC-related proteins, namely CD44 and CD133, in two different tumor areas (the representative tumor center and the deepest invasive front) in 286 cases of primary CRC using tissue microarrays. Altered expression of all EMT-related proteins was more frequently observed in the invasive front than in the tumor center. Altered expression of E-cadherin, beta-catenin and vimentin significantly associated with aggressive tumor characteristics. In particular, loss of E-cadherin expression in the invasive front significantly associated with shorter disease-free survival (DFS, P=0.002) and overall survival (OS, P=0.007). Overexpression of vimentin in the invasive front significantly correlated with poor OS (P=0.028). Loss of CD44 expression both in the tumor center and in the invasive front significantly associated with unfavorable clinicopathological characteristics. In the invasive front, but not in the tumor center, combination of the altered protein expression patterns of E-cadherin, beta-catenin, vimentin, snail and CD133 significantly associated with aggressive clinicopathological factors and shorter DFS (P=0.003) and OS (P=0.005). The present data suggest that cancer cells expressing a combination of altered EMT-and CSC-related proteins may represent a potential biomarker for aggressive tumor behavior and may be a possible future candidate for molecular targeted treatments for CRC.</P>
Hospital-Based Surveillance of Infection-Related Mortality in South Korea
Choi, Jun Yong,Cheong, Hee-Jin,Chun, Byung Chul,Park, Hye Kyung,Lee, Han Sung,Lee, Hagyung,Kim, Sang IL,Kim, Min Ja,Kim, Sung Soo,Chang, Hyun-Ha,Lee, Sun Hee,Park, Kyung Hwa,Chung, Doo Ryeon,Chung, Ji SAGE Publications 2009 Public health reports Vol.124 No.6
The Influence of Flip-flops Gait on the Muscle Activity of Tibilalis anterior and Gastrocnemius
Choi, Jung Hyun,Song, Mi Ri,Lee, Joong Hyun,Kim, Hong Rae,Park, Si Eun,Kim, Ji Sung,Kwak, Dae Young,Lee, Sang Bin,Kim, Nyeon Jun,Koo, Ja Pung,Kim, Soon Hee International Academy of Physical Therapy Research 2013 Journal of International Academy of Physical Ther Vol.4 No.2
The fact that flip-flops, one of many different types of unstable shoes, are light and relatively easy to put on, accounts for their popularity among people. But because flip-flops rely heavily on the support of a single thong between your first and second toes, they impose a huge amount of pressure onto lower leg. Thus in the following experiment we tried to examine the different effects of flip-flops and running shoes in terms of their effect on muscle activity and fatigue of tibialis anterior and gastrocnemius during walking. In order to measure an electromyogram we used Free EMG system. 10 men and 10 women in running shoes ran on treadmills for 15 minutes at 4.8km/h, 2 days later the same experiment was carried out, but this time, in flip-flops. p value turned out to be greater than .05 and thus there was no considerable difference between the effects of flip-flops and running shoes on muscle activity and fatigue during walking. Therefore we conclude that despite the fact that flip-flops are considered unstable, their effects on muscle activity and fatigue of tibialis anterior and gastrocnemius are negligible.
DEVELOPMENTALLY REGULATED EXPRESSION OF THE RICE CALMODULIN PROMOTER IN TRANSGENIC TOBACCO PLANTS
Choi, Young-Ju,Lim, Chae-Oh,Koo, Ja-Choon,Lee, Sang-Hyeung,Kang, Mi-Sun,Bahk, Jeong-Dong,Cho, Moo-Je Gyeongsang National University Chinju, Korea 1992 Plant molecular biology and biotechnology research Vol.1992 No.
Choi, Ji-Young,Lee, Sang-Hyoung,Park, Chan-Young,Heo, Won-Do,Kim, Jong-Cheol,Kim, Min-Chul,Chung, Woo-Sik,Moon, Byeong-Cheol,Cheong, Yong-Hwa,Kim, Cha-Young,Yoo, Jae-Hyuk,Koo, Ja-Choon,Ok, Hyun-Mi,Chi Plant molecular biology and biotechnology research 2002 Plant molecular biology and biotechnology research Vol.2002 No.-
Plants express numerous calmodulin (CaM) isoforms that exhibit differential activation or inhibition of CaM-dependent enzymes in vitro; however, their specificities toward target enzyme/protein binding are uncertain. A random peptide library displaying a 22-mer peptide on a bacteriophage surface was constructed to screen peptides that specifically bind to plant CaM isoforms(soybean calmodulin(ScaM)-1 and SCaM-4 were used in this study)in a Ca^(2+)-dependent manner. The deduced amino acid sequence analyses of the respective 80 phage clones that were independently isolated via affinity panning revealed that SCaM isoforms require distinct amino acid sequences for optimal binding. SCaM-1-binding peptides conform to a 1-5-10 ((FILVW)XXX(FILV)XXXX(FILVW)) motif(where X denotes any amino acid), whereas SCaM-4-binding peptide sequences conform to a 1-8-14 ((FILVW)XXXXXX(FAILVW)XXXXX(FILVW) motif. Theses motifs are classified based on the positions of conserved hydrophobic residues. To examine their binding properties further, two representative peptides from each of the SCaM isofrom-binding sequences were synthesized and analyzed via gel mobility shift assays, Trp fluorescent spectra analyses, and phosphodiesterase competitive inhibition experiments. The results of these studies suggest that SCaM isoforms possess different binding sequences for optimal target interaction, which therefore may provide a molecular basis for CaM isoform-specific function in plants. Furthermore, the isolated peptide sequences may serve not only as useful CaM-binding sequence references but also as potential reagents for studying CaM isoform-specific function in vivo.