Asymptotical Outer Synchronization for the Controlled Complex Dynamic Networks with Unknown Bounded Interaction

Qingfeng Chen,Yinhe Wang,Xiao Tang 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.4

This paper investigates the problem of asymptotical outer synchronization for two complex dynamic networks (CDNs), one of which is called as the drive network and another is as the response network. Compared with the existing literature, the unknown bounded state interaction between the two CDNs is focused with the unknown and non-dissipative outer coupling configuration matrices of the drive-response networks, and thus the dynamic models of CDNs with interaction are proposed more general in structural form. Then, combined with the matrix analysis and Lyapunov stability methods, the relevant mathematical assumptions are proposed based on actual engineering background, with which the adaptive outer synchronization controller is synthesized in this paper. Therefore, the matrix straightening operation in the existing literature is avoided in this paper, which leads to the clearer structure of the designed controller. Finally, the effectiveness of the proposed method is verified by numerical simulation with the comparative example.

Identification of DNA methylation and genetic alteration simultaneously from a single blood biopsy

Chen Xiaomin,Liu Jiahui,Li Jun,Xie Yinpeng,Yu Zichen,Shen Lu,Liu Qingfeng,Wu Wei,Zhao Qiang,Lin Haoxiang,Liu Gaotong,Luo Qiuping,Yang Ling,Huang Yi,Zhao Meiru,Yi Xin,Xia Xuefeng 한국유전학회 2023 Genes & Genomics Vol.45 No.5

Background High-throughput sequencing of blood cell-free DNA (cfDNA) techniques offer an opportunity to characterize and monitor cancer rapidly in a non-invasive and real-time manner. Nonetheless, there lacks a tool within therapeutic arsenal to identify multi-omics alterations simultaneously from a single biopsy. In current times, bisulfite-based sequencing detects 5mC and 5hmC at single-base resolution is the golden standard of DNA methylation, while the degradation of DNA and biased sequencing data are the problems of this method. Objective To identify the consistency analysis of methylation and genetic variation with single library, we presented a platform detecting multi-omics data simultaneously from a single blood biopsy using bisulfite-free method of genomic methylation sequencing (GM-seq) mediated by TET enzyme. Methods We detected methylomic and genetic changes simultaneously from a single blood biopsy in NA12878 and randomly chose ten blood biopsies from colorectal cancer or lung cancer patients to validate the ability of GM-seq. Results Similar cytosine methylation level between whole genome bisulfite sequencing (WGBS) and GM-seq were identified in NA12878. Moreover, longer insert size, CpGs coverage and GC distribution were outperformed than WGBS. In addition, the comparison of the single nucleotide polymorphism (SNP), insertion-deletion (Indel) and copy number variation (CNV) in NA12878 or ctDNA from liver cancer between GM-seq and whole genome sequencing (WGS) show a good consistency, indicating that this method is feasible for detecting genetic variation in blood. Conclusion In conclusion, our work demonstrated a method for identification of the methylated modification and genetic variations simultaneously from a single blood biopsy.

Mechanical Property and Microstructure of Fly Ash-Based Geopolymer Activated by Sodium Silicate

Qingfeng Lv,Jingjing Yu,Fengling Ji,Liuyang Gu,Yi Chen,Xiaokang Shan 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.5

Sodium silicate is one of the common alkali activators of geopolymers. The modulus, concentration and dosage of sodium silicate have significant effects on the activation of fly ash, the strength and microstructure of geopolymer. In this paper, unconfined compressive strength test, X-ray diffraction analysis (XRD), Fourier transform infrared light (FTIR), 29Si nuclear magnetic resonance (29Si NMR), scanning electron microscope and energy disperse spectroscopy (SEM-EDS), and physisorption experiment (BET) were carried out to study the effects of the sodium silicate modulus and dosage on the mechanical property and microstructure of fly ash-based geopolymer. The results indicated that the main product of the geopolymer activated by sodium silicate was hydrated sodium aluminosilicate (N-A-S-H). When modulus value decreased and meanwhile dosage of sodium silicate increased, the reorganization and polymerization of gel products were accelerated so that the integrity and continuity of the microstructure of geopolymer were improved, and then the strength increased. When the modulus of sodium silicate was 3.28, the maximum value of the strength was at the dosage of 10%. According to this study, it was investigated that modulus value and dosage of sodium silicate had obvious influence on the alkali- activated reaction of fly ash, which can provide an engineering reference for the special soil solidification with geopolymers.

Development Issues of An ISG PM Machine and Control System

Xiaojiang Chen,Murray Edington,Roger Thornton,Yunzhou Fang,Qingfeng Peng 전력전자학회 2007 ICPE(ISPE)논문집 Vol.- No.-

This paper focuses on addressing some practical considerations in developing an ISG PM system for hybrid electric-vehicle (HEV) applications. Extensive practical test results and theoretical analyses are presented and analyzed. Firstly, the ISG PM machine design is discussed in term of the machine size, pole-pair number, permanent magnet flux, inductance, etc. A cost-effective machine design example, which was successfully demonstrated in a mild ISG HEV application, is analyzed. Its performance test results are evaluated. Subsequently, the impacts of the position sensors on the ISG performance are investigated exclusively. Three prominent position sensor candidates are studied in detail to examine their limitation and feasibility for ISG applications. Furthermore, the control related issues are discussed. The torque control of the ISG machine is implemented through vector control algorithm. Flux-weakening control is employed to achieve a wide speed range of constant-power operation. The impact of the inverter DC-link voltage variation is explored. In addition the digital control delay influence and its effective compensation strategy are addressed.

Phylogenetic Diversity of Microbial Communities in Real Drinking Water Distribution Systems

Pinpin Lu,Chao Chen,Qingfeng Wang,Zhao Wang,Xiaojian Zhang,Shuguang Xie 한국생물공학회 2013 Biotechnology and Bioprocess Engineering Vol.18 No.1

Microbial regrowth in drinking water distribution systems (DWDS) is a major concern in the water supply industry. Detailed knowledge of the microbial community in DWDS will be of great importance for assessing the microbiological risks of drinking water. The spatial heterogeneity of microbial community structures in the bulk waters of a large real DWDS was investigated using 16S rRNA clone library analysis. The results indicate that high residual chlorine in drinking water could not control microbial regrowth in DWDS. The bacterial communities in the bulk waters were spatially heterogenic, mainly composed of Alphaproteobacteria and Betaproteobacteria (or Cyanobacteria). Microorganisms from the genera Acinetobacter, Sphingomonas and Gemella were detected,implying there is microbiological risk from drinking water. This work provides new insight into microbial ecology in DWDS.

A Phase Shift Full Bridge Converter with Information Integrated for Battery Charger

Ruwen Wang,Siyu Tong,Qingfeng Zhang,Yu Chen 전력전자학회 2023 ICPE(ISPE)논문집 Vol.2023 No.-

Bidirectional communication between the battery charger and the Lithium-ion batteries is very important to ensure the safe operation of batteries. There is a trend towards the elimination of communication lines by means of wireless technology. Noticing that the information from the charger to the battery (C2B) is simple logic signals 0 or 1, this paper proposes an idea to integrate the information directly into the power transfer path of the battery charger with phase shift full bridge structure, to save hardware cost. The information is converted to senary data and integrated into the charger through the frequency-shift modulation and the phase-shift modulation. The logical information is then demodulated by the controllers on the battery side. The proposed method achieves the C2B information transmission with no extra hardware cost and little negative effect on the charging process. The effectiveness is verified by experiments.

Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy

Ni Wang,Junyan Yang,Ruijun Chen,Yunyun Liu,Shunjie Liu,Yining Pan,Qingfeng Lei,Yuzhou Wang,Lu He,Youqiang Song,Zhong Li The Korean Society of Ginseng 2023 Journal of Ginseng Research Vol.47 No.3

Background: Alzheimer's disease (AD) is a common form of dementia, and impaired mitophagy is a hallmark of AD. Mitophagy is mitochondrial-specific autophagy. Ginsenosides from Ginseng involve in autophagy in cancer. Ginsenoside Rg1 (Rg1 hereafter), a single compound of Ginseng, has neuroprotective effects on AD. However, few studies have reported whether Rg1 can ameliorate AD pathology by regulating mitophagy. Methods: Human SH-SY5Y cell and a 5XFAD mouse model were used to investigate the effects of Rg1. Rg1 (1µM) was added to β-amyloid oligomer (AβO)-induced or APPswe-overexpressed cell models for 24 hours. 5XFAD mouse models were intraperitoneally injected with Rg1 (10 mg/kg/d) for 30 days. Expression levels of mitophagy-related markers were analyzed by western blot and immunofluorescent staining. Cognitive function was assessed by Morris water maze. Mitophagic events were observed using transmission electron microscopy, western blot, and immunofluorescent staining from mouse hippocampus. The activation of the PINK1/Parkin pathway was examined using an immunoprecipitation assay. Results: Rg1 could restore mitophagy and ameliorate memory deficits in the AD cellular and/or mouse model through the PINK1-Parkin pathway. Moreover, Rg1 might induce microglial phagocytosis to reduce β-amyloid (Aβ) deposits in the hippocampus of AD mice. Conclusion: Our studies demonstrate the neuroprotective mechanism of ginsenoside Rg1 in AD models. Rg1 induces PINK-Parkin mediated mitophagy and ameliorates memory deficits in 5XFAD mouse models.

Effect of Physical Activity on the Association Between Diet and Constipation: Evidence From the National Health and Nutrition Examination Survey 2007-2010

Shijun Lai,Changdong Zhu,Xiaoqing Zhou,Qingfeng Zeng,Lihua Huang,Xiaodong Cao,Qiang Zhou,Yuhua Zhong,Jinjing Huang,Guifang Zeng,Hong Chen 대한소화기 기능성질환∙운동학회 2024 Journal of Neurogastroenterology and Motility (JNM Vol.30 No.3

Background/AimsPrevious studies have shown that diet and physical activity can influence constipation. However, the combined effect of diet and physical activity on constipation remains unclear. MethodsConstipation was defined based on stool consistency and frequency, while overall diet quality was assessed using Healthy Eating Index (HEI)-2015 scores. Participants were categorized into low (metabolic equivalent [MET]-min/wk < 500) and high physical activity groups (MET-min/wk ≥ 500). The association between diet and constipation across physical activity groups was analyzed using survey logistic regression and restricted cubic splines. ResultsHigher HEI-2015 scores were associated with reduced constipation risk in the high physical activity group when constipation was defined by stool consistency (odds ratio [OR], 0.98; 95% confidence interval [CI], 0.97-0.99). However, in the low physical activity group, increased HEI-2015 scores did not significantly affect constipation risk (OR, 1.01; 95% CI, 0.97-1.05). Similar results were found when constipation was defined based on stool frequency. In the high physical activity group, increased HEI-2015 scores were significantly associated with a reduced constipation risk (OR, 0.96; 95% CI, 0.94-0.98). Conversely, in the low physical activity group, increased HEI-2015 scores did not affect the risk of constipation (OR, 0.96; 95% CI, 0.90-1.03). ConclusionsOur findings suggest that a higher HEI-2015 score is negatively associated with constipation among individuals with high physical activity levels but not among those with low physical activity levels. This association was consistent when different definitions of constipation were used. These results highlight the importance of combining healthy diet with regular physical activity to alleviate constipation.

Performance optimization of flexible a-Si:H solar cells with nanotextured plasmonic substrate by tuning the thickness of oxide spacer layer

Xiao, Huapeng,Wang, Jun,Huang, Hongtao,Lu, Linfeng,Lin, Qingfeng,Fan, Zhiyong,Chen, Xiaoyuan,Jeong, Chaehwan,Zhu, Xufei,Li, Dongdong Elsevier 2015 Nano energy Vol.11 No.-

<P><B>Abstract</B></P> <P>Plasmonic thin film solar cells deposited on periodically textured photonic crystal substrates have been extensively studied since the substantially enhanced light absorption. The reduction of parasitic absorption losses in the metal and spacer layers becomes one of the key issues to achieve high efficiency solar cells. Herein, plasmonic amorphous silicon (a-Si:H) flexible thin film solar cells with different thickness of oxide spacer layers are systematically investigated. An increase of the spacer layer thickness leads to an evolution in surface morphology of AZO and final devices. More intriguingly, the increase of spacer layer thickness reduces the absorption in Ag layer while induces more absorption in spacer layer. The highest light absorption in silicon layer is observed as applying 100nm spacer layer, which is further verified by electrical measurements. Our observations demonstrate a versatile and convenient route towards rational design of light harvesting nanostructure for high performance plasmonic solar cells based on a broad range of materials.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Amorphous silicon thin film solar cells are constructed on patterned substrates. </LI> <LI> The devices properties are studied as a function of spacer layer thickness. </LI> <LI> An increase of spacer layer thickness reduces the absorption loss of Ag layer. </LI> <LI> The device with 100nm spacer layer confines more incident light in silicon layer. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Purification efficiency of eight aquatic plant species in an artificial floating island system in relation to extracellular enzyme activity and microbial community

Lei Li,You Feng,Jinye Li,Qing Li,Ting Liu,Qingfeng Chen 대한환경공학회 2022 Environmental Engineering Research Vol.27 No.6

The floating island system exploits the combination of aquatic plants, microorganisms, and extracellular enzymes to purify wastewater. We investigated the purification efficiency of eight aquatic plant species cultured in wastewater. The relationships of plant purification capacity with extracellular enzyme activity and microbial community were analyzed to explore the crucial factors that affect the plant purification capacity and the mechanism of pollutants removal in different plant systems. Three plant species, namely Oenanthe javanica, Thalia dealbata, and lris pseudacorus, were most effective for purification of ammonium-nitrogen (NH₄<SUP>+</SUP>-N), total phosphate (TP), and chemical oxygen demand (COD) with maximum efficiencies of 76.09, 85.87, and 89.10%, respectively. Urease, alkaline phosphatase (AP), and β-glucosidase activities were significantly and positively correlated with root system development (P < 0.05). Activities of urease and AP were positively correlated with NH₄<SUP>+</SUP>-N and TP removal, respectively. The magnitude of urease and AP activity was generally consistent with the plant’s capacity to remove NH₄<SUP>+</SUP>-N and TP. β-Glucosidase activity and COD removal were not significantly correlated. The dominant microbial phylum in each species treatment was Proteobacteria. Alphaproteobacteria and Bacteroidia showed > 1% relative abundance and greater involvement in degradation of pollutants in the experimental system.