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      • KCI등재

        The Effect of Financial Innovation and Supervision on the Performance -Evidence from Commercial Banks in China-

        ( Liu Qian ),( Shim Hyeong Sop ),( Jin Shan Yue ) 한중사회과학학회 2021 한중사회과학연구 Vol.19 No.4

        As one of the three modules of the financial industry, the banking industry has a wide impact, and a special and important position in the entire financial system and the national economy. In the context of the turbulent international financial situation and the rapid changes in financial technology, China’s banking industry is facing challenges in various aspects. Chinese commercial banks need to accelerate the pace of innovation within the appropriate regulatory scope to improve their core competitiveness. This study investigates the impact of financial innovation and financial supervision on commercial banks’ business performance. We use panel data on 40 listed commercial banks in China during 2011-2020 and utilize a regression model. The findings show that both financial innovation and financial supervision have a positive impact on commercial banks’ commercial performance. Furthermore, strengthening financial supervision has a facilitating effect on financial innovation to improve bank performance.

      • KCI등재

        Adsorption and recycling of Cd(II) from wastewater using straw cellulose hydrogel beads

        Fudong Wang,Jin Li,Yuan Su,Qian Li,Baoyu Gao,Qinyan Yue,Weizhi Zhou 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.80 No.-

        Environment-friendly straw cellulose hydrogel beads (SCHBs) were applied for Cd(II) recovery andrecycling from solution. The SCHBs presented good adsorption capacity for Cd(II) of 95.62 mg/g at 313.5 K. These Cd(II) loaded SCHBs were recycled for CdS in-situ synthesis and employed as photocatalyst in thedegradation of methylene blue under visible light irradiation. Both TEM and SEM images confirmed thatthe recycled CdS nanoparticles within SCHBs are smaller than 20 nm in size, and XRD patterns wereconsistent with the metallic crystallinity of CdS. The recycled SCHBs-CdS composites exhibited excellentphotocatalytic degradation ability and reusability.

      • KCI등재

        Dynamic analysis of Ca^(2+) level during bovine oocytes maturation and early embryonic development

        Su Li Liang,Qian Jun Zhao,Xiang Chen Li,Ya Ping Jin,Yi Peng Wang,Xiao Hua Su,Wei Jun Guan,Yue Hui Ma 대한수의학회 2011 Journal of Veterinary Science Vol.12 No.2

        Mammalian oocyte maturation and early embryo development processes are Ca^(2+)-dependent. In this study, we used confocal microscopy to investigate the distribution pattern of Ca^(2+) and its dynamic changes in the processes of bovine oocytes maturation, in vitro fertilization (IVF), parthenogenetic activation (PA) and somatic cell nuclear transfer (SCNT) embryo development. During the germinal vesicle (GV) and GV breakdown stage, Ca^(2+) was distributed in the cortical ooplasm and throughout the oocytes from the MI to MII stage. In IVF embryos, Ca^(2+)was distributed in the cortical ooplasm before the formation of the pronucleus. In 4-8 cell embryos and morulas, Ca^(2+) was present throughout the blastomere. In PA embryos, Ca^(2+) was distributed throughout the blastomere at 48 h, similar to in the 4-cell and 8-cell phase and the morula. At 6 h after activation, there was almost no distribution of Ca^(2+) in the SCNT embryos. However, Ca^(2+) was distributed in the donor nucleus at 10 h and it was distributed throughout the blastomere in the 2-8 cell embryos. In this study, Ca^(2+) showed significant fluctuations with regularity of IVF and SCNT groups, but PA did not. Systematic investigation of the Ca^(2+) location and distribution changes during oocyte maturation and early embryo development processes should facilitate a better understanding of the mechanisms involved in oocyte maturation, reconstructed embryo activation and development, ultimately improving the reconstructed embryo development rate.

      • SCIESCOPUSKCI등재

        Ginsengenin derivatives synthesized from 20(R)-panaxotriol: Synthesis, characterization, and antitumor activity targeting HIF-1 pathway

        Guo, Hong-Yan,Xing, Yue,Sun, Yu-Qiao,Liu, Can,Xu, Qian,Shang, Fan-Fan,Zhang, Run-Hui,Jin, Xue-Jun,Chen, Fener,Lee, Jung Joon,Kang, Dongzhou,Shen, Qing-Kun,Quan, Zhe-Shan The Korean Society of Ginseng 2022 Journal of Ginseng Research Vol.46 No.6

        Background: Ginseng possesses antitumor effects, and ginsenosides are considered to be one of its main active chemical components. Ginsenosides can further be hydrolyzed to generate secondary saponins, and 20(R)-panaxotriol is an important sapogenin of ginsenosides. We aimed to synthesize a new ginsengenin derivative from 20(R)-panaxotriol and investigate its antitumor activity in vivo and in vitro. Methods: Here, 20(R)-panaxotriol was selected as a precursor and was modified into its derivatives. The new products were characterized by <sup>1</sup>H-NMR, <sup>13</sup>C-NMR and HR-MS and evaluated by molecular docking, MTT, luciferase reporter assay, western blotting, immunofluorescent staining, colony formation assay, EdU labeling and immunofluorescence, apoptosis assay, cells migration assay, transwell assay and in vivo antitumor activity assay. Results: The derivative with the best antitumor activity was identified as 6,12-dihydroxy-4,4,8,10,14-pentamethyl-17-(2,6,6-trimethyltetrahydro-2H-pyran-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl(tert-butoxycarbonyl)glycinate (A11). The focus of this research was on the antitumor activity of the derivatives. The efficacy of the derivative A11 (IC<sub>50</sub> < 0.3 µM) was more than 100 times higher than that of 20(R)- panaxotriol (IC<sub>50</sub> > 30 µM). In addition, A11 inhibited the protein expression and nuclear accumulation of the hypoxia-inducible factor HIF-1α in HeLa cells under hypoxic conditions in a dose-dependent manner. Moreover, A11 dose-dependently inhibited the proliferation, migration, and invasion of HeLa cells, while promoting their apoptosis. Notably, the inhibition by A11 was more significant than that by 20(R)-panaxotriol (p < 0.01) in vivo. Conclusion: To our knowledge, this is the first study to report the production of derivative A11 from 20(R)-panaxotriol and its superior antitumor activity compared to its precursor. Moreover, derivative A11 can be used to further study and develop novel antitumor drugs.

      • KCI등재

        Thermo-mechanical stress analysis of feed-water valves in nuclear power plants

        Wen-qing Li,Lei Zhao,Yang Yue,Jia-yi Wu,Zhi-jiang Jin,Jin-yuan Qian 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.3

        Feed-water valves (FWVs) are used to regulate the flow rate of water entering steam generators, whichare very important devices in nuclear power plants. Due to the working environment of relatively highpressure and temperature, there is strength failure problem of valve body in some cases. Based on thethermo-fluid-solid coupling model, the valve body stress of the feed-water valve in the opening processis investigated. The flow field characteristics inside the valve and temperature change of the valve bodywith time are studied. The stress analysis of the valve body is carried out considering mechanical stressand thermal stress comprehensively. The results show that the area with relatively high-velocity areamoves gradually from the bottom of the cross section to the top of the cross section with the increase ofthe opening degree. The whole valve body reaches the same temperature of 250C at the time of 1894 s. The maximum stress of the valve body meets the design requirements by stress assessment. This workcan be referred for the design of FWVs and other similar valves.

      • KCI등재

        Minimum life-cycle cost design of ice-resistant offshore platforms

        Da-yong Zhang,Gang Li,Qian-jin Yue 국제구조공학회 2009 Structural Engineering and Mechanics, An Int'l Jou Vol.31 No.1

        In China, the oil and natural gas resources of Bohai Bay are mainly marginal oil fields. It is necessary to build both ice-resistant and economical offshore platforms. However, risk is involved in the design, construction, utilization, maintenance of offshore platforms as uncertain events may occur within the life-cycle of a platform under the extreme ice load. In this study, the optimum design model of the expected life-cycle cost for ice-resistant platforms based on cost-effectiveness criterion is proposed. Multiple performance demands of the structure, facilities and crew members, associated with the failure assessment criteria and evaluation functions of costs of construction, consequences of structural failure modes including damage, revenue loss, death and injury as well as discounting cost over time are considered. An efficient approximate method of the global reliability analysis for the offshore platforms is provided, which converts the implicit nonlinear performance function in the conventional reliability analysis to linear explicit one. The proposed life-cycle optimum design formula are applied to a typical ice-resistant platform in Bohai Bay, and the results demonstrate that the life-cycle cost-effective optimum design model is more rational compared to the conventional design.

      • SCIESCOPUS

        Minimum life-cycle cost design of ice-resistant offshore platforms

        Li, Gang,Zhang, Da-Yong,Yue, Qian-Jin Techno-Press 2009 Structural Engineering and Mechanics, An Int'l Jou Vol.31 No.1

        In China, the oil and natural gas resources of Bohai Bay are mainly marginal oil fields. It is necessary to build both ice-resistant and economical offshore platforms. However, risk is involved in the design, construction, utilization, maintenance of offshore platforms as uncertain events may occur within the life-cycle of a platform under the extreme ice load. In this study, the optimum design model of the expected life-cycle cost for ice-resistant platforms based on cost-effectiveness criterion is proposed. Multiple performance demands of the structure, facilities and crew members, associated with the failure assessment criteria and evaluation functions of costs of construction, consequences of structural failure modes including damage, revenue loss, death and injury as well as discounting cost over time are considered. An efficient approximate method of the global reliability analysis for the offshore platforms is provided, which converts the implicit nonlinear performance function in the conventional reliability analysis to linear explicit one. The proposed life-cycle optimum design formula are applied to a typical ice-resistant platform in Bohai Bay, and the results demonstrate that the life-cycle cost-effective optimum design model is more rational compared to the conventional design.

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