푸른길 공원의 대기 환경 특성에 관한 연구

민경우,이경석,박옥현,윤관주,김도술,박세일,정원삼,이대행,조영관,Min, Kyoung-Woo,Lee, Kyoung-Soek,Park, Ok-Hyun,Yoon, Kwan-Ju,Kim, Do-Sool,Park, Se-Il,Jeung, Won-Sam,Lee, Dae-Hang,Cho, Young-Gwan 한국환경보건학회 2015 한국환경보건학회지 Vol.41 No.3

Objectives: This study aimed to survey the characteristics of air quality and meteorological conditions in a greenway park. Methods: We measured meteorological and health related factors, including noise, particulate matter ($PM_{10}$) and selected gaseous air pollutants at three locations in a greenway park and on a general roadside as comparison. The measurements were repeated four times from April to October 2014. Results: The average air temperature in the greenway park was $20.7^{\circ}C$ which was $1-2^{\circ}C$ lower than on the general roadside. The average $PM_{10}$ concentration in the greenway park was $85.0{\mu}g/m^3$, a level 2-3 times lower than that at the roadside. The noise level at the greenway site was 4.4 dB(A)- 23.0 dB(A) lower than at the roadside. The average CO, $CO_2$, $SO_2$ and NOx concentrations in the greenway park were lower than at the roadside. The average phytoncide and anions concentrations in the greenway park were higher than at the roadside. Conclusions: The urban forest of the greenway park may have some impact on air quality and meteorological conditions.

공동주택 주차장의 축적먼지 중 미량원소성분 분석과 오염원 평가

배건호(Gun Ho Bae),정철수(Cheol Su Jung),박규태(Kyu Tae Park),이명숙(Myoung Sook Lee),신동찬(Dong Chan Shin),김용혜(Yong Hye Kim),윤민혜(Min Hye Yoon),한영진(Young Jin Han),최혁(Hyuek Choi),백성옥(Sung Ok Baek) 大韓環境工學會 2011 대한환경공학회지 Vol.33 No.10

공동주택 주차장의 먼지오염실태를 연구하기 위하여 2010년 3월말에서 6월초까지 대구지역 공동주택 36곳의 지상주차장(36지점)과 지하주차장(36지점)을 대상으로 채취한 총 72개의 시료를 100 μm 이하로 체거름하고 산추출한 후 ICP로 14개원소를 분석하였다. 농축계수를 이용한 미량원소성분의 발생원 평가결과는 지상주차장과 지하주차장 모두 Fe, K, Mg, Mn, Na, V의 성분은 자연적인 발생원에 의한 영향을 받고 있는 반면에 Cd, Cr, Cu, Ni, Pb, Zn의 성분은 인위적인 발생원에 의한 영향을 받고 있는 것으로 나타났다. 한편 Ca은 지상주차장의 경우에는 자연적인 발생원의 영향을 받았고, 지하주차장의 경우에는 인위적인 발생원의 영향을 받은 것으로 나타났다. 미량원소성분의 농도분석 결과는 자연적인 발생원과 관련된 성분이 인위적인 발생원과 관련된 성분보다 매우 높은 농도를 보였다. 인위적인 발생원성분의 기여도는 지하주차장이 지상주차장보다 높았으며, 미량원소성분의 평균농도 또한 지하주차장이 지상주차장보다 높았다. 오염지수를 이용한 중금속성분의 오염도를 평가한결과는 지하주차장이 지상주차장보다 5.5배정도 높게 오염된 것으로 나타났다. 미량원소성분간의 상관성 분석결과는 지상주차장이 지하주차장에 비해 유의한 상관성을 나타내는 항목이 많았으며, 특히 자연적 발생원 성분간 유의한 상관성이 더욱 크게 나타났다. 또한 유해 중금속성분과 지하주차장의 영향인자간의 상관성을 분석한 결과는 주차대수(공간)가 적은 지점이 큰 지점보다, 환기장치를 가동하지 않은 지점이 가동한 지점보다, 그리고 최근 도색년도와 청소일이 오래된 지점이 상대적으로 유해중금속을 많이 함유하고 있었다. In order to investigate the degree of apartment parking lot dust contamination, total 72 samples of parking lot dust (36 from ground parking lots and 36 from the underground parking lots) were collected in Daegu city from the end of March to the early June 2010. The dust samples were sieved below 100 μm, and analysed by ICP for 14 elements after an acid extraction. Results obtained from the source assessment of trace element using enrichment factor showed that Fe, K, Mg, Mn, Na and V were influenced by natural sources, while Cd, Cr, Cu, Ni, Pb and Zn were influenced by anthropogenic sources in both the ground parking lot and the underground parking lot. And results showed that Ca were influenced by natural sources in the ground parking lot, but influenced by anthropogenic sources in the underground parking lot. The measured values were remarkably higher in components from natural sources than in components from anthropogenic sources. Underground parking lot dust was more affected by anthropogenic sources and contaminated compared with the ground parking lot dust. Pollution index of heavy metals revealed that underground parking lot dust was 5.5 times more contaminated with heavy metal components than the ground parking lot dust. The results of correlation analysis among trace elements indicated that components in the ground parking lot were more correlated than those in the underground parking lot, and especially more correlated with natural sources-natural sources. Analysis for correlations between components and influencing factors in the underground parking lot showed that concentrations of heavy metals were higher with smaller number of parking spaces and no ventilation system, and older apartments in last paint and cleaning had relatively higher contents of heavy metals than those of recently painted and cleaned.

Increase in Aminotransferase Levels during Urinary Tract Infections in Children

Park, Ju Yi,Ko, Kyung Ok,Lim, Jae Woo,Cheon, Eun Jeong,Yoon, Jung Min The Korean Society of Pediatric Gastroenterology 2013 Pediatric gastroenterology, hepatology & nutrition Vol.16 No.2

Purpose: The aim of this study was to evaluate the prevalence of increased aminotransferase levels and to identify associated factors in children admitted to hospital with urinary tract infections (UTIs). Methods: The study included children with a diagnosis of UTI who were admitted to the Konyang University Hospital from January 2007 to May 2011. The total number of patients was 249 and the mean age was $15.88{\pm}28.21$ months. UTI was defined as a positive urine culture (> $10^5$/colony forming unit [CFU]) with pyrexia. Patients were treated by intravenous antibiotics, such as ampicillin/sulbactam, aminoglycoside, cephalosporins or vancomycin. Patients with neonatal jaundice or other liver disease were excluded. We investigated the relationship of aminotransferase levels with the type of antibiotic, degree of vesicoureteral reflux (VUR), and causative organisms. Results: Children with increased aminotransferase levels were younger than those with normal levels (p=0.001), but white blood cell count, platelet count, causative organisms, type of antibiotics and presence of VUR were not associated with aminotransferase levels. Aminotransferase levels became normal within 1 month after discharge without special measures, except in 1 case. Conclusion: We found that many children with UTI have abnormal aminotransferase levels. In most cases, this change is mild and self-limiting. We conclude that increased aminotransferase level increase during UTI do not require unnecessary tests and excessive treatment.

Nocardioides currus sp. nov., isolated from a mobile car air-conditioning system

Park, Yu Jin,Jeong, Sang Eun,Jung, Hye Su,Park, So Yoon,Jeon, Che Ok Microbiology Society 2018 International journal of systematic and evolutiona Vol.68 No.9

Wg/Wnt1 and Erasp link ER stress to proapoptotic signaling in an autosomal dominant retinitis pigmentosa model

Park Jung-Eun,Lee Jiyoun,Ok Soonhyuck,Byun Seunghee,Chang Eun-Ju,Yoon Sung-Eun,Kim Young-Joon,Kang Min-Ji 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

The endoplasmic reticulum (ER) is a subcellular organelle essential for cellular homeostasis. Perturbation of ER functions due to various conditions can induce apoptosis. Chronic ER stress has been implicated in a wide range of diseases, including autosomal dominant retinitis pigmentosa (ADRP), which is characterized by age-dependent retinal degeneration caused by mutant rhodopsin alleles. However, the signaling pathways that mediate apoptosis in response to ER stress remain poorly understood. In this study, we performed an unbiased in vivo RNAi screen with a Drosophila ADRP model and found that Wg/Wnt1 mediated apoptosis. Subsequent transcriptome analysis revealed that ER stress-associated serine protease (Erasp), which has been predicted to show serine-type endopeptidase activity, was a downstream target of Wg/Wnt1 during ER stress. Furthermore, knocking down Erasp via RNAi suppressed apoptosis induced by mutant rhodopsin-1 (Rh-1P37H) toxicity, alleviating retinal degeneration in the Drosophila ADRP model. In contrast, overexpression of Erasp resulted in enhanced caspase activity in Drosophila S2 cells treated with apoptotic inducers and the stabilization of the initiator caspase Dronc (Death regulator Nedd2-like caspase) by stimulating DIAP1 (Drosophila inhibitor of apoptosis protein 1) degradation. These findings helped identify a novel cell death signaling pathway involved in retinal degeneration in an autosomal dominant retinitis pigmentosa model.

Complete Spinal Cord Injury Treatment Using Autologous Bone Marrow Cell Transplantation and Bone Marrow Stimulation with Granulocyte Macrophage-Colony Stimulating Factor: Phase I/II Clinical Trial

Yoon, Seung Hwan,Shim, Yu Shik,Park, Yong Hoon,Chung, Jong Kwon,Nam, Jung Hyun,Kim, Myung Ok,Park, Hyung Chun,Park, So Ra,Min, Byoung-Hyun,Kim, Eun Young,Choi, Byung Hyune,Park, Hyeonseon,Ha, Yoon Wiley (John WileySons) 2007 Stem Cells Vol.25 No.8

<P>To assess the safety and therapeutic efficacy of autologous human bone marrow cell (BMC) transplantation and the administration of granulocyte macrophage-colony stimulating factor (GM-CSF), a phase I/II open-label and nonrandomized study was conducted on 35 complete spinal cord injury patients. The BMCs were transplanted by injection into the surrounding area of the spinal cord injury site within 14 injury days (n = 17), between 14 days and 8 weeks (n = 6), and at more than 8 weeks (n = 12) after injury. In the control group, all patients (n = 13) were treated only with conventional decompression and fusion surgery without BMC transplantation. The patients underwent preoperative and follow-up neurological assessment using the American Spinal Injury Association Impairment Scale (AIS), electrophysiological monitoring, and magnetic resonance imaging (MRI). The mean follow-up period was 10.4 months after injury. At 4 months, the MRI analysis showed the enlargement of spinal cords and the small enhancement of the cell implantation sites, which were not any adverse lesions such as malignant transformation, hemorrhage, new cysts, or infections. Furthermore, the BMC transplantation and GM-CSF administration were not associated with any serious adverse clinical events increasing morbidities. The AIS grade increased in 30.4% of the acute and subacute treated patients (AIS A to B or C), whereas no significant improvement was observed in the chronic treatment group. Increasing neuropathic pain during the treatment and tumor formation at the site of transplantation are still remaining to be investigated. Long-term and large scale multicenter clinical study is required to determine its precise therapeutic effect. Disclosure of potential conflicts of interest is found at the end of this article.</P>

Block copolymer multiple patterning integrated with conventional ArF lithography

Park, Seung Hak,Shin, Dong Ok,Kim, Bong Hoon,Yoon, Dong Ki,Kim, Kyoungseon,Lee, Si Yong,Oh, Seok-Hwan,Choi, Seong-Woon,Jeon, Sang Chul,Kim, Sang Ouk Royal Society of Chemistry 2010 SOFT MATTER Vol.6 No.1

<P>We present block copolymer multiple patterning as an efficient and truly scalable nanolithography for sub-20 nm scale patterning, synergistically integrated with conventional ArF lithography. The directed assembly of block copolymers on chemically patterned substrates prepared by ArF lithography generated linear vertical cylinder arrays with a 20 to 30 nm diameter, enhancing the pattern density of the underlying chemical patterns by a factor of two or three. This self-assembled resolution enhancement technique affords a straightforward route to highly ordered sub-20 nm scale features <I>via</I> conventional lithography.</P> <P>Graphic Abstract</P><P>Block copolymer multiple patterning has been developed as a truly scalable pattern resolution enhancement technique, synergistically integrated with conventional 193 nm ArF lithography. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b913853f'> </P>

L - Arginine Production by Fusant MWE 9031 of Coryneform bacteria

Park, Chung,Choi, Ok Yoon,Ok, Chi Young,Lee, Sae Bae,Lim, Bun Sam 한국농화학회 1990 Applied Biological Chemistry (Appl Biol Chem) Vol.33 No.2

In order to overproduce L-arginine, intergeneric protoplast fusion between Brevibacterium flavum and Corynebacterium glutamicum was performed. For the protoplast fusion, various amino acid analogs, sulfa drugs and/or purine base analogs resistant mutants were isolated from B. flavum ATCC 21493 and C. glutamicum ATCC 21831. The optimum conditions for protoplast fusion of these mutants were examined. Fusani MWE 9031 was found co accumulate a large amount of L-arginine in the culture medium. The concentration of accumulated L-arginine reached 32.5㎎/㎖ with a medium containing 10% glucose. Also the characteristics of culture condition in fusant MWE 9031 was investigated to compare with those of parental strains.

Densification and Dielectric Properties of Glass/Ceramic Composites Sintered with Various Borosilicate Glass

Yoon, Sang Ok,Kim, Kwan Soo,Kim, Shin,Shim, Sang Heung,Park, Jong Guk Trans Tech Publications, Ltd. 2007 Materials science forum Vol.544 No.-

<P>Al2O3 and TiO2 were sintered with three types (lead, zinc, bismuth) of borosilicate glass. Their microwave dielectric properties and sintering behavior were investigated as functions of glass type, glass addition (10~50 vol%) and sintering temperature (600~950°C for 2 hrs). Sintering characteristics were well described in terms of softening temperature, second phase, and excessive liquid. In particular, Bi2O3 addition to the glass enhanced reaction with Al2O3 and TiO2 to form liquid phase and second phase. In terms of dielectric properties glass/Al2O3 composites for application to substrates while glass/TiO2 composites for filters were shown to be appropriate.</P>

Detection of Oyster-Associated Norovirus by Microchip Electrophoresis of an Amplified cDNA

Ok-Hee Kim,Yeong-min Sin,Ki-Hyun Kim,Kun-sang Park,Dae-Byung Kim,Byung-Yoon Ahn,오호경 한국식품영양과학회 2007 Preventive Nutrition and Food Science Vol.12 No.2

Noroviruses, members of the family Caliciviridae, are often found in shellfish grown in polluted water and are emerging as a leading cause of foodborne disease worldwide. As the presence of norovirus in food commodities becomes an important medical and social issue, there are increasing needs for designing improved detection methods for the virus. In this study, we tested the Agilent 2100 Bioanalyzer for the analysis of norovirus DNA amplified from oyster samples. Microchip electrophoresis provided us with more accurate information, compared to conventional agarose gel electrophoresis, in the resolution and quantification of amplified products. The development of an improved method for food-associated noroviruses would contribute to a rapid identification of contaminated food and improve our understanding of the modes of food contamination and norovirus transmission.