A New Approach to Objective Evaluation of the Success of Nasal Septum Perforation

Ozturk, Sinan,Zor, Fatih,Ozturk, Serdar,Kartal, Ozgur,Alhan, Dogan,Isik, Selcuk Korean Society of Plastic and Reconstructive Surge 2014 Archives of Plastic Surgery Vol.41 No.4

Background Perforations in the nasal septum (NSP) give rise not only to disintegration of the septum anatomy but also impairment in normal nasal physiology. The successes of these surgical techniques are usually equated to anatomical closure of the perforation. The goal of this study is to evaluate the subjective and objective results of our surgical technique for septal perforation surgery. Methods All NSPs in the six patients were closed by inferior turbinate flap. The Nasal Obstruction Symptom Evaluation (NOSE) instrument was used to evaluate the preoperative and postoperative subjective sensation of nasal obstruction. Measurement of preoperative and postoperative nasal airway resistance was performed using active anterior rhinomanometry which is an objective test. Wilcoxson signed rank test and Spearman correlation test were used to analyze correlation between NOSE scores and rhinomanometric measurements. Results The full closure of the septal perforations was noted in 100% of patients. The total NOSE score was 14 preoperatively and one postoperatively. The improvement in NOSE scores was statistically significant ($P{\leq}0.002$). The mean preoperative total resistance (ResT150) value was $0.13Pa/cm^3s^{-1}$, which is below the normal range ($0.16-0.31Pa/cm^3s^{-1}$), while the mean postoperative ResT150 value was $0.27Pa/cm^3s^{-1}$. The correlation between the improvement in NOSE scores and improvements in ResT150 values was statistically significant. Conclusions Surgical approaches should aim to solve both the anatomical and physiological problems of NSP. The application of subjective and objective tests in the postoperative period will help surgeons assess the applied techniques.

The Relationship between Angiotensin-II Type 1 Receptor Gene Polymorphism and Repolarization Parameters after a First Anterior Acute Myocardial Infarction

Onder Ozturk,Unal Ozturk,Sebnem Nergiz,M. Zulkif Karahan 대한심장학회 2016 Korean Circulation Journal Vol.46 No.6

Background and Objectives: Genetic influence on T-wave peak to End (Tpe) time in patients with a first anterior acute myocardial infarction (AMI) is uncertain. A polymorphism in the angiotensin-II type 1 receptor (AT1R) gene was discovered recently. The polymorphism consists of an A or C variant, given three different possible genotypes: AA, AC, CC. The purpose of this study was to determine the effects of polymorphism of the AT1R gene polymorphism on Tpe after a first anterior AMI. Subjects and Methods: The subjects were 142 patients (110 men, 32 women, 58±13 years) with a first anterior AMI; ten patients were excluded from this study. Based on the polymorphism of the AT1R gene, they were classified into two groups: Group 1 (AA genotype) of 91 patients and group 2 (AC and CC genotype) of 41 patients. A 12-lead resting ECG was recorded at admission to the coronary care unit in patients with anterior AMI and were manually measured with a ruler. QTc, QTd, QTcd, Tpe, Tpe/QT parameters were measured. Results: There was no significant difference in the baseline characteristics of patients (p>0.05). We found significant reduction in QTc, QTd, QTcd, Tpe, Tpe/QT indices Group 1 (AA genotype) (mean 66±28 ms) than group 2 (AC and CC genotype) (mean 95±34 ms) (p<0.05). Conclusion: In patients with a first anterior AMI, AT1R gene polymorphisms may influence on repolarization parameters. Although further studies are required.

A New Approach to Objective Evaluation of the Success of Nasal Septum Perforation

Sinan Ozturk,Fatih Zor,Serdar Ozturk,Ozgur Kartal,Dogan Alhan,Selcuk Isik 대한성형외과학회 2014 Archives of Plastic Surgery Vol.41 No.4

Background: Perforations in the nasal septum (NSP) give rise not only to disintegration ofthe septum anatomy but also impairment in normal nasal physiology. The successes of thesesurgical techniques are usually equated to anatomical closure of the perforation. The goal ofthis study is to evaluate the subjective and objective results of our surgical technique forseptal perforation surgery. Methods: All NSPs in the six patients were closed by inferior turbinate flap. The NasalObstruction Symptom Evaluation (NOSE) instrument was used to evaluate the preoperativeand postoperative subjective sensation of nasal obstruction. Measurement of preoperative andpostoperative nasal airway resistance was performed using active anterior rhinomanometrywhich is an objective test. Wilcoxson signed rank test and Spearman correlation test were usedto analyze correlation between NOSE scores and rhinomanometric measurements. Results: The full closure of the septal perforations was noted in 100% of patients. The totalNOSE score was 14 preoperatively and one postoperatively. The improvement in NOSE scoreswas statistically significant (P≤0.002). The mean preoperative total resistance (ResT150) valuewas 0.13 Pa/cm3s-1, which is below the normal range (0.16–0.31 Pa/cm3s-1), while the meanpostoperative ResT150 value was 0.27 Pa/cm3s-1. The correlation between the improvement inNOSE scores and improvements in ResT150 values was statistically significant . Conclusions: Surgical approaches should aim to solve both the anatomical and physiologicalproblems of NSP. The application of subjective and objective tests in the postoperative periodwill help surgeons assess the applied techniques.

NO<SUB>x</SUB> emission modeling at cement plants with co-processing alternative fuels using ANN

Betul OZTURK,Onur OZTURK,Aykan KARADEM?R 대한환경공학회 2022 Environmental Engineering Research Vol.27 No.5

The use of wastes as alternative fuel (AF) at the cement plants for clinkerization processes has increased in recent years as sustainable waste management. Such co-processing of AFs at cement plants causes some changes in the composition of the plant emissions, depending on waste type, kiln thermal power, thermal substitution rate, etc. Emissions of nitrogen oxides (NOx) are among the major environmental concerns in these plants. The paper includes a modeling study of NOx emissions at a cement plant during the co-processing of AFs. Due to the non-linear characteristic of the relationship between operational parameters and NOx emissions, the artificial neural network (ANN) approach was applied and studied. The study showed that NOx emissions can be predicted satisfactorily by using ANN at cement plants. Therefore, the model proposed may be used by cement plant operators to estimate their emission levels before starting the use of a new fuel source.

ON ALMOST ALPHA-COSYMPLECTIC MANIFOLDS WITH SOME NULLITY DISTRIBUTIONS

Ozturk, Hakan The Honam Mathematical Society 2019 호남수학학술지 Vol.41 No.2

The object of the paper is to investigate almost alpha-cosymplectic (${\kappa},{\mu},{\nu}$) spaces. Some results on almost alpha-cosymplectic (${\kappa},{\mu},{\nu}$) spaces with certain conditions are obtained. Finally, we give an example on 3-dimensional case.

Site-directed Mutagenesis of Five Conserved Residues of Subunit I of the Cytochrome cbb₃ Oxidase in Rhodobacter capsulatus

Ozturk, Mehmet,Gurel, Ekrem,Watmough, Nicholas J.,Mandaci, Sevnur Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.5

Cytochrome $cbb_3$ oxidase is a member of the heme-copper oxidase superfamily that catalyses the reduction of molecular oxygen to the water and conserves the liberated energy in the form of a proton gradient. Comparison of the amino acid sequences of subunit I from different classes of heme-copper oxidases showed that transmembrane helix VIII and the loop between transmembrane helices IX and X contain five highly conserved polar residues; Ser333, Ser340, Thr350, Asn390 and Thr394. To determine the relationship between these conserved amino acids and the activity and assembly of the $cbb_3$ oxidase in Rhodobacter capsulatus, each of these five conserved amino acids was substituted for alanine by site-directed mutagenesis. The effects of these mutations on catalytic activity were determined using a NADI plate assay and by measurements of the rate of oxygen consumption. The consequence of these mutations for the structural integrity of the $cbb_3$ oxidase was determined by SDS-PAGE analysis of chromatophore membranes followed by TMBZ staining. The results indicate that the Asn390Ala mutation led to a complete loss of enzyme activity and that the Ser333Ala mutation decreased the activity significantly. The remaining mutants cause a partial loss of catalytic activity. All of the mutant enzymes, except Asn390Ala, were apparently correctly assembled and stable in the membrane of the R. capsulatus.

Effects of Perceived Parental Attitudes on Children's Views of Smoking

Ozturk, Candan,Kahraman, Seniha,Bektas, Murat Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.4

Background: The aim of this study was to examine the effects of perceived parental attitudes on children's discernment of cigarettes. Materials and Methods: The study sample consisted of 250 children attending grades 6, 7 and 8. Data were collected via a socio-demographic survey questionnaire, the Parental Attitude Scale (PAS) and the Decisional Balance Scale (DBS). Data analysis covered percentages, medians, one-way analysis of variance (ANOVA) and post-hoc tests using a statistical package. Results: There were 250 participants; 117 were male, 133 were female. The mean age was $13.1{\pm}0.98$ for the females and $13.3{\pm}0.88$ for the males. A statistically significant difference was found in the children's mean scores for 'pros' subscale on the Decisional Balance Scale (DBS) according to perceived parental attitudes (F=3.172, p=0.025). There were no statistically significant differences in the DBS 'cons' subscale scores by perceived parental attitudes. Conclusions: It was determined that while perceived parental attitudes affect children's views on advantages of smoking, they have no effect on children's views on its disadvantages.

Effects of Cigarette Smoking across Three Generations and of Perceptions of the Smoking-Cancer Relationship on the Cigarette Smoking Status of Turkish University Students

Ozturk, Candan,Bektas, Murat,Mert, Ozlem Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11

Background: This descriptive and cross-sectional study aimed to investigate effects of cigarette smoking across three generations and perceptions of the smoking-cancer relationship on the cigarette smoking status of Turkish university students. Materials and Methods: The study sample comprised of 434 university students studying in different departments of a university. Data were collected using a socio-demographic data collection form and the Decisional Balance Scaleqand evaluated using the Mann-Whitney U test, CHAID and multiple regression analyses. Results: The average age of the students participating in the study is 19.6+.5.0, some 11.3% of the students reporting that they smoked cigarettes. No statistically significant relationship was ascertained between the cigarette smoking statuses of the students based on the cigarette smoking status of their grandparents (p=0.144). but there was alink to that of their parents (p=0.002). The difference between the cigarette smoking ratios of the students based on their perceptions of smoking-cancer relationship was statistically significant (p<0.001). Believing that there is a relationship between smoking and cancer decreased likelihood of cigarette smoking 3.7 fold. Cigarette smoking by grandparents, and believing that there is a relationship between smoking and cancer, and cigarette smoking by parents explained 8.3% of the cigarette smoking status of the students. Conclusions: While cigarette smoking by grandparents only indirectly influences cigarette smoking by the students, believing that there is a relationship between smoking and cancer, and cigarette smoking by parents are influential variables in determining cigarette smoking by Turkish students.

Optimum cost design of RC columns using artificial bee colony algorithm

Ozturk, Hasan Tahsin,Durmus, Ahmet Techno-Press 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.45 No.5

Optimum cost design of columns subjected to axial force and uniaxial bending moment is presented in this paper. In the formulation of the optimum design problem, the height and width of the column, diameter and number of reinforcement bars are treated as design variables. The design constraints are implemented according to ACI 318-08 and studies in the literature. The objective function is taken as the cost of unit length of the column consisting the cost of concrete, steel, and shuttering. The solution of the design problem is obtained using the artificial bee colony algorithm which is one of the recent additions to metaheuristic techniques. The Artificial Bee Colony Algorithm is imitated the foraging behaviors of bee swarms. In application of this algorithm to the constraint problem, Deb's constraint handling method is used. Obtained results showed that the optimum value of numerical example is nearly same with the existing values in the literature.

The Contagion of Covid-19 Pandemic on The Volatilities of International Crude Oil Prices, Gold, Exchange Rates and Bitcoin

OZTURK, M. Busra Engin,CAVDAR, Seyma Caliskan Korea Distribution Science Association 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.3

In the international markets, financial variables can be volatile and may affect each other, especially in the crisis times. COVID-19, which began in China in 2019 and spread to many countries of the world, created a crisis not only in the global health system but also in the international financial markets and economy. The purpose of this study is to analyze the contagious effect of the COVID-19 pandemic on the volatility of selected financial variables such as Bitcoin, gold, oil price, and exchange rates and the connections between the volatilities of these variables during the pandemic. For this aim, we use the ARMA-EGARCH model to measure the impact of volatility and shocks. In other words, it is aimed to measure whether the impact of the shock on the financial variables of the contagiousness of the epidemic is also transmitted to the markets. The data was collected from secondary and daily data from September 2th 2019 to December 20th, 2020. It can be said that the findings obtained have statistically significant effects on the conditional variability of the variables. Therefore, there are findings that the shocks in the market are contaminated with each other.