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Nguyen Thi Mai Tho,Bui The Huy,Dang Nguyen Nha Khanh,Ho Nguyen Nhat Ha,Vu Quang Huy,Ngo Thi Tuong Vy,Do Manh Huy,Duong Phuoc Dat,Nguyen Thi Kim Phuong 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.12
Novel highly active visible-light photocatalysts in the form of zinc bismuth oxide (ZnBi2O4) and graphite hybrid composites were prepared by coupling via a co-precipitation method followed by calcination at 450 oC. The asprepared ZnBi2O4-graphite hybrid composites were tested for the degradation of rhodamine B (RhB) solutions under visible-light irradiation. The existence of strong electronic coupling between the two components within the ZnBi2O4- graphite heterostructure suppressed the photogenerated recombination of electrons and holes to a remarkable extent. The prepared composite exhibited excellent photocatalytic activity, leading to more than 93% of RhB degradation at an initial concentration of 50mg·L1 with 1.0 g catalyst per liter in 150min. The excellent visible-light photocatalytic mineralization of ZnBi2O4-1.0graphite in comparison with pristine ZnBi2O4 could be attributed to synergetic effects, charge transfer between ZnBi2O4 and graphite, and the separation efficiency of the photogenerated electrons and holes. The photo-induced h+ and the superoxide anion were the major active species responsible for the photodegradation process. The results demonstrate the feasibility of ZnBi2O4-1.0graphite as a potential heterogeneous photocatalyst for environmental remediation.
Nguyen Thu Hien,Nguyen Duc Quan,Kim Lien Nguyen Thi,Thi Thanh Ngan Nguyen,Nguyen Thi Phuong Mai,Tran Ngoc Dung,Nguyen Huy Hoang 한국유전학회 2023 Genes & Genomics Vol.45 No.4
Background Androgens and androgen receptor (AR) are critical regulators of the masculinization process in male sexual development. The absence of a functioning AR results in the development of the androgen insensitivity syndrome (AIS), a rare disorder of sexual development (DSD) characterized by the external genitalia feminization, gynecomastia, and impaired spermatogenesis. Objective To determine the AR gene mutations associated with male DSD in four unrelated Vietnamese patients. Methods To detect the disease-causing mutations, whole exome sequencing (WES) was performed on four patients diagnosed with AIS. Sanger sequencing was then used for validation of the identified mutations. Finally, 12 web-based tools, three-dimensional protein modeling software, and the guidelines issued by the American College of Medical Genetics and Genomics were used to assess the potential pathogenicity of these mutations. Results Four distinct novel mutations, namely c.1834T > A (p.Cys612Ser), c.2122 C > G (p.Leu708Val), c.2630T > G (p.Phe877Cys), and c.2641 C > A (p.Leu881Met) in the AR gene, were identified in four AIS patients using WES. The in silico analysis results revealed that the Cys612, Leu708, Phe877, and Leu881 sites are important for an appropriate response to androgens of the AR, and mutation at these sites can have adverse effects on the AR functions, androgen–AR interaction, and AR signaling pathway. Conclusions WES and in silico analyses strongly suggested that four novel AR mutations are pathogenic and have led to the development of AIS in the four Vietnamese patients under consideration.
Truong Giang Nguyen,Thanh Khiem Nguyen,Ham Hoi Nguyen,Hong Son Trinh,Tuan Hiep Luong,Minh Trong Nguyen,Van Duy Le,Hai Dang Do,Kieu Hung Nguyen,Van Minh Do,Quang Huy Tran,Cuong Thinh Nguyen 한국간담췌외과학회 2024 Annals of hepato-biliary-pancreatic surgery Vol.28 No.1
Backgrounds/Aims: Parenchymal-sparing anatomical hepatectomy (Ps–AH) based on portal ramification of the right anterior section (RAS) is a new technique to avoid unnecessarily transecting too much liver parenchyma, especially in cases of major anatomical hepatectomy. Methods: We prospectively assessed 26 patients with primary hepatic malignancies having undergone major Ps–AH based on portal ramification of the RAS from August 2018 to August 2022 (48 months). The perioperative indications, clinical data, intra-operative index, pathological postoperative specimens, postoperative complications, and follow-up results were retrospectively evaluated. Results: Among the 26 patients analyzed, there was just one case that had intrahepatic cholangiocarcinoma The preoperative level of α– Fetoprotein was 25.2 ng/mL. All cases (100%) had Child–Pugh A liver function preoperatively. The ventral/dorsal RAS was preserved in 19 and 7 patients, respectively. The mean surgical margin was 6.2 mm. The mean surgical time was 228.5 minutes, while the mean blood loss was 255 mL. In pathology, 5 cases (19.2%) had microvascular invasion, and in the group of HCC patients, 92% of all cases had moderate or poor tumor differentiation. Six cases (23.1%) of postoperative complications were graded over III according to the Clavien–Dindo system, including in three patients resistant ascites or intra-abdominal abscess that required intervention. Conclusions: Parenchymal-sparing anatomical hepatectomy based on portal ramification of the RAS to achieve R0-resection was safe and effective, with favorable short-term outcomes. This technique can be used widely in clinical practice.
Quasi-steady Across-wind Aerodynamic Damping of Tall Structures
Nguyen, Cung Huy,Long, Doan-Sy,Nguyen, Dinh Tung Council on Tall Building and Urban Habitat Korea 2019 International journal of high-rise buildings Vol.8 No.4
The paper presents a generalization of existing analytical approaches to determine the across-wind aerodynamic damping of tall structures through the quasi-steady theory. The theory takes into account the nature of non-uniform wind, structural mode shapes and the variation of structural parameters. Numerical applications on a prototype high-rise building and a real sculptural tower point out that the common approach may be over simplified, giving rise to inappropriate predictions of the aerodynamic damping. The role of the structural mode shapes, usually being neglected for uniform structures, is then highlighted.
Nguyen Duc Huy,Thiyagarajan Saravanakumar,하상훈,박승문 한국생물공학회 2020 Biotechnology and Bioprocess Engineering Vol.25 No.3
Enzymatic hydrolysis of hemicelluloses in biomass feedstocks requires multiple enzymes for saccharification to fermentable monosaccharides. Considering the high cost of enzymes, the need for enzymes in the cocktail for maximum saccharification can be minimized using a statistically significant experimental design. In the present study, response surface methodology was used to optimize the saccharification of wheat arabinoxylan and pretreatment of barley straw. A hemicellulase enzyme mixture consisting of recombinant xylanase (rPcXynC), arabinanase (rPcAra), and bifunctional β-xylosidase/L-arabinofuranosidase (rPcXyl) was used. A central composite design was used to evaluate and confirm the effectiveness and interactions of these enzymes along with reaction time. A 100% saccharification of 1 g of wheat arabinoxylan was achieved using 21.85 U, 6.025 U, and 182 U of rPcXynC, rPcAra, and rPcXyl, respectively, for 11.46 h. Subsequently, using pretreated barley straw as a substrate, a maximum saccharification of 42% was achieved in 12 h using an enzyme cocktail of 25 U rPcXynC, 5 U rPcAra, and 200 U rPcXyl. The total hydrolysis of pretreated barley straw was increased to 1.71% by the addition of acetyl xylan esterase as a pretreatment factor followed by optimization of enzyme cocktail. The experimental values under the optimum conditions were consistent with the predicted values and a minimum cocktail was involved for a synergistic effect of the enzymes.
Huy Hai Nguyen,Xuan Quang Duong,이승수(Seung Soo Lee),정재동(Jae Dong Chung) 대한설비공학회 2021 설비공학 논문집 Vol.33 No.8
This study aimed to estimate the performance of a storage cooling system for roving personal air conditioning where a phase change material (PCM) was used as a condenser. The modeling on direct expansion air conditioning requires two-phase analysis. We applied 1-D two phase flow method for refrigerant inside tubes and effective thermal conductivity model outside tubes for PCM. Results were compared with those of a previous experience model which assumed a fixed ratio of super-heating region (10%), two-phase region (80%), and sub-cooling region (10%). The desired system discharge power was 600 Wh. Results showed that the previous experience method had an over-estimated performance due to the assumption of constant temperature applied over whole tube length while the current model coupled with 1-D two phase model and effective thermal conductivity model could cover the detailed heat transfer involved in the roving personal air-conditioning including developing a two-phase region.
Nguyen-Huy, Chinh,Shin, Eun Woo Elsevier 2016 Fuel Vol.179 No.-
<P><B>Abstract</B></P> <P>ZrO<SUB>2</SUB>-impregnated macro–mesoporous red mud catalysts were successfully prepared for the catalytic cracking of vacuum residue (VR) in a steam atmosphere under a fixed-bed reaction condition at 500°C for 2h. Zirconia was homogeneously dispersed in the macro–mesoporous red mud, and the resulting catalyst had a high surface area, large pore volume, and highly ordered pore structure dimensions. When compared to a ZrO<SUB>2</SUB>-impregnated mesoporous red mud, the ZrO<SUB>2</SUB>-impregnated macro–mesoporous red mud catalysts exhibited better catalytic behavior for the steam catalytic cracking of VR. The presence of a macroporous structure ameliorated the catalytic activity due to improved accessibility to active hydrogenation sites and oxidative cracking, which in turn induced higher conversion values, a greater liquid yield, and a higher H/C ratio in the liquid product when compared to a ZrO<SUB>2</SUB>-impregnated mesoporous red mud catalyst. Furthermore, the ZrO<SUB>2</SUB>-impregnated macro–mesoporous red mud catalyst showed better regenerability due to both a large pore volume and the good stability of the pore structure.</P> <P><B>Highlights</B></P> <P> <UL> <LI> ZrO<SUB>2</SUB>-impregnated macro–mesoporous red mud catalysts were successfully prepared. </LI> <LI> ZrO<SUB>2</SUB>-impregnated macro–mesoporous red mud showed excellent catalytic activity. </LI> <LI> The presence of a macroporous structure enhanced the catalytic activity. </LI> <LI> The ZrO<SUB>2</SUB>(3)/MaRM-150 catalysts showed excellent regenerability. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>