Augered, Cast-In-Place Piles in the United States

Michael W. O’ Neill,Min Gu Kim 한국지반공학회 2002 지반 : 한국지반공학회지 Vol.18 No.8

Evolving Cancer Classification in the Era of Personalized Medicine: A Primer for Radiologists

Ailbhe C. O’Neill,Jyothi P. Jagannathan,Nikhil H. Ramaiya 대한영상의학회 2017 Korean Journal of Radiology Vol.18 No.1

Traditionally tumors were classified based on anatomic location but now specific genetic mutations in cancers are leading to treatment of tumors with molecular targeted therapies. This has led to a paradigm shift in the classification and treatment of cancer. Tumors treated with molecular targeted therapies often show morphological changes rather than change in size and are associated with class specific and drug specific toxicities, different from those encountered with conventional chemotherapeutic agents. It is important for the radiologists to be familiar with the new cancer classification and the various treatment strategies employed, in order to effectively communicate and participate in the multi-disciplinary care. In this paper we will focus on lung cancer as a prototype of the new molecular classification.

Combatting Student Alienation: Community Building in the Academic Philosophy Café

Rory O’Neill,Wang Huiling 강원대학교 인문과학연구소 2021 Journal of Humanities Therapy Vol.12 No.1

AMPK and Exercise: Glucose Uptake and Insulin Sensitivity

Hayley M. O’Neill 대한당뇨병학회 2013 Diabetes and Metabolism Journal Vol.37 No.2

AMPK is an evolutionary conserved sensor of cellular energy status that is activated during exercise. Pharmacological activation of AMPK promotes glucose uptake, fatty acid oxidation, mitochondrial biogenesis, and insulin sensitivity; processes that are reduced in obesity and contribute to the development of insulin resistance. AMPK deficient mouse models have been used to provide direct genetic evidence either supporting or refuting a role for AMPK in regulating these processes. Exercise promotes glucose uptake by an insulin dependent mechanism involving AMPK. Exercise is important for improving insulin sensitivity; however, it is not known if AMPK is required for these improvements. Understanding how these metabolic processes are regulated is important for the development of new strategies that target obesity-induced insulin resistance. This review will discuss the involvement of AMPK in regulating skeletal muscle metabolism (glucose uptake, glycogen synthesis, and insulin sensitivity).

AMPK and Exercise: Glucose Uptake and Insulin Sensitivity

Hayley M. O’Neill 대한당뇨병학회 2013 Diabetes and Metabolism Journal Vol.37 No.1

AMPK is an evolutionary conserved sensor of cellular energy status that is activated during exercise. Pharmacological activation of AMPK promotes glucose uptake, fatty acid oxidation, mitochondrial biogenesis, and insulin sensitivity; processes that are reduced in obesity and contribute to the development of insulin resistance. AMPK deficient mouse models have been used to provide direct genetic evidence either supporting or refuting a role for AMPK in regulating these processes. Exercise promotes glucose uptake by an insulin dependent mechanism involving AMPK. Exercise is important for improving insulin sensitivity; however,it is not known if AMPK is required for these improvements. Understanding how these metabolic processes are regulated is important for the development of new strategies that target obesity-induced insulin resistance. This review will discuss the involvement of AMPK in regulating skeletal muscle metabolism (glucose uptake, glycogen synthesis, and insulin sensitivity).

엠마우스 복지관 사례를 통한 가톨릭교회의 사회복지

천노엘 신부(Rev. Patrick Noel O’neill ) 전남대학교 종교문화연구소 2007 종교문화학보 Vol.4 No.-

이 글은 아일랜드에서 사제서품을 받고 1957년에 한국에 와 50년간 지체장애인공동체인 엠마우스공동체를 일구어온 천노엘 신부의 사회복지 활동의 과정을 일부 소개하고, 정신지체장애인의 복지를 위해 필요하고 요청되는 것이 무엇인지를 언급한 것이다. 장애인들은 인간다운 대우를 받지 못해 왔으며, 특히 정신지체장애인은 심지어 죽음마저도 비인격적인 경우가 적지 않다. 저자에 의하면, 장애인을 위한 사회복지는 대규모 수용시설보다 지역사회 중심의 소집단 복지서비스가 적합하다. 그는 1981년에 국내 최초로, 3인으로 구성된 정신지체인 그룹홈을 시작함으로써 이것을 실천해 오고 있다. 처음에는 이해해주는 사람이 거의 없었지만, 점차 나아져 1989년부터는 정부의 지원을 받게 되었고, 1995년에는 사회복지법인으로 법적 인정도 받게 되었다. 장애인 복지에서 가장 중요한 것은 취업이라고 저자는 주장한다. 아직은 이것을 이해하지 못하는 사람들이 너무 많지만, 장애인들도 비장애인들과 똑같은 욕구를 갖고 있다는 사실을 비장애인들이 인지하는 것이 중요하다. 장애인 복지의 궁극적 목표인 지역사회 참여와 통합은 장애인들이 진정으로 원하는 욕구와 서비스가 충족될 때 실현 가능하다. 모두가 서울대에 입학할 수는 없으며, 모두가 일등이 될 수는 없다. 정신지체장애인은 어느 면에서는 실패자들일 수 있지만, 건전한 사회라면 실패자를 위한 자리가 꼭 마련되어야 하며, 실패자들을 환영하는 사회가 되어야 한다. 정신지체장애인들은 오히려 가장 정직한 사람들이다. 근년 들어 엠마우스친구들의 적극적인 지역사회 참여 활동으로 점차 그들의 사회적 가치를 인정받아 가고 있지만, 가장 근원적으로는 지역사회의 비장애인들이 장애인들에 대한 편견을 없애고 긍정적으로 바라보는 인식이 필요하다. The Christian religion was born and nourished within a Jewish milieu and was greatly influenced by Jewish culture. When you read the Old Testament which is a history of the Jewish People you see that the Jews had a special concern for the marginalized peoples in society and offered services to the poor and the weak. The corporal works of mercy as found in the Old Testament are the foundation for the evolution of human services. Old Testament rituals had no internal worth unless they were accompanied with concern for the weak ones of society. Jesus Christ during his lifetime expressed in word and deed this concern for the needs of the poor and the marginalized. In the Mathew Chapter 25(35-37). we read that on the Final Day we will be judged on how we treated our neighbour in need. From the Early Church times up to the Middle Ages Christian believers were very much involved in caring for the needy. For them caring for the poor and the needy was caring for the Hidden Christ. “What you do to the least of those little ones you do unto Me”. In this period the poor and needy were cared for within the local community, and were treated as a person with dignity(Hidden Christ) and respect. All those services were done voluntarily. Around the Middle Ages and on to the 18century, due to pestilence, extensive costly wars, and the Industrial Revolution, poverty became a major social issue, and the manner of offering services to the marginalized ones changed. Rather than community based services segregation and congregation of the poor and the weak became the model of services. Due to the Enlightment christian fervour and devotion began to decrease, you had huge numbers of large segregated institutions being build and staffed by payed carers. In a word the Judea-Christian model of Human Services was dying. With the turn of the twentieth century you saw the birth of many new nations as they won freedom from their old colonizers-you saw the human rights movement lead by Dr. Martin King and the great document of-Gaudium et Spes from Vatican 11. The basic Christian believe-that man is made in Gods image-was bringing about a greater awareness of the dignity of man. Hence the model for Judea-Christian human services is recognizing the dignity of the human person and offering them services in the local community where they will not feel the wound of segregation. Answering the Cry of Humanity is the role of Christian human services.

THE EXTREME HOSTS OF EXTREME SUPERNOVAE

Neill, James D.,Sullivan, Mark,Gal-Yam, Avishay,Quimby, Robert,Ofek, Eran,Wyder, Ted K.,Howell, D. Andrew,Nugent, Peter,Seibert, Mark,Martin, D. Christopher,Overzier, Roderik,Barlow, Tom A.,Foster, Ka IOP Publishing 2011 The Astrophysical journal Vol.727 No.1

THE EFFECTS OF PROTEIN HYDROLYSATES FED UNDER TWO DIFFERENT FEEDING REGIMES ON THE IMMUNITY AND GROWTH OF THE SOUTH AFRICAN ABALONE Haliotis midae

Neill J. Goosen,Lourens F. de Wet,Johann F. Gorgens 한국수산과학회 양식분과 2015 한국수산과학회 양식분과 학술대회 Vol.2015 No.5

THE LOCAL HOSTS OF TYPE Ia SUPERNOVAE

Neill, James D.,Sullivan, Mark,Howell, D. Andrew,Conley, Alex,Seibert, Mark,Martin, D. Christopher,Barlow, Tom A.,Foster, Karl,Friedman, Peter G.,Morrissey, Patrick,Neff, Susan G.,Schiminovich, David IOP Publishing 2009 The Astrophysical journal Vol.707 No.2

Effect of Xylanase on Performance and Apparent Metabolisable Energy in Starter Broilers Fed Diets Containing One Maize Variety Harvested in Different Regions of China

O'Neill, H.V. Masey,Liu, N.,Wang, J.P.,Diallo, A.,Hill, S. Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.4

The objective of this study was to investigate the variability in broiler performance, apparent metabolisable energy (AME) and ileal digestible energy (IDE) between five different maize samples fed with and without xylanase at 16,000 U/kg. Various in vitro characterisations were conducted to determine if any could predict performance or AME. Samples of the maize were harvested in five diverse regions and fed individually in a mash diet as follows (g/kg): test maize 608.3; soya bean meal (SBM) 324.1; poultry fat 25.2; salt 4.6; met 2.6; lys 1.6; thr 0.5; limestone 9.7, dical 18.4; vit/min 5.0; CP 210 and ME (kcal/kg) 3,085. The diets were fed to 720 broilers with 6 replicates, each containing 12 birds per treatment, from 0 to 18 d of age. Maize samples were analysed for starch, protein, crude fibre, fat, protein solubility index (PSI) and vitreousness using near infra red reflectance spectroscopy (NIR). They were also assayed using an in vitro starch digestibility method. The results showed that there was no effect of harvest region on the feed intake (FI), body weight gain (BWG) or feed conversion ratio (FCR) of the broilers over the 18 d period (p = 0.959, 0.926, 0.819 respectively). There was an improvement in all parameters with the addition of xylanase (FI p = 0.011; BWG and FCR p<0.001). There was a significant positive effect of xylanase on IDE, AME, IDE Intake (IDEI) and AME intake (AMEI) (p<0.0001 in all cases). Although there was no significant effect of maize source, there was a strong trend towards variability in IDE (p = 0.066) and AME (p = 0.058). There were no significant correlations (p<0.05) between any proximate or physiochemical values and any performance or AME values. This may suggest that none of those selected were suitable predictors for performance or AME. The broilers performed well according to the breed guidelines, with slightly increased FI, increased BWG and similar FCR prior to the addition of xylanase. When FCR and BWG were analysed with FI as a covariate, xylanase addition remained significant suggesting that the improvement in BWG and FCR was driven by an increase in digestibility and nutrient availability.