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- 저자 : Naresh, R. (검색결과 203 건)
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Evaluation of Ascorbic Acid Treatment in Clinical and Subclinical Mastitis of Indian Dairy Cows
Naresh, Ram,Dwivedi, S.K.,Swarup, D.,Patra, R.C. Asian Australasian Association of Animal Productio 2002 Animal Bioscience Vol.15 No.6
A study was carried out to assess the therapeutic effect of ascorbic acid in mastitis of dairy cows. The herd with a population of 250-275 lactating cows was screened for clinical and subclinical mastitis for a period of 5 months. Based on inclusion and exclusion criteria, eighteen animals each with clinical and subclinical mastitis in one quarter only were selected as study population. Twelve cows (group A) with normal udder and health were also selected as a healthy control. Clinical mastitis cows were grouped as B (n=12) and C (n=6). Cows of group B were treated with ascorbic acid at 25 mg/kg, subcutaneously for 5 consecutive days and intramammary infusion (Ampicillin sodium 75 mg and Cloxacillin sodium 200 mg/infusion) based on antibiotic sensitivity test, till complete recovery. Group C cows received only intramammary infusion till the complete recovery. Eighteen subclinical mastitis cows were divided in group D (n=12) and E (n=6). Cows of group D were treated with ascorbic acid at 25 mg/kg subcutaneously for 5 consecutive days while group E did not receive any treatment. California mastitis test (CMT), somatic cell count (SCC), physical changes of udder and milk were used to diagnose and classify the mastitis. Evaluation of the therapy was based on CMT score and physical changes of udder and milk. Sample size calculation was also performed but was not followed for control groups due to scarcity of cases. Adequate blinding was done when and where required to avoid the biases. Confounding variables like herd, age of the cow, stage of the lactation, season and geographical region were duly considered and adequate blocking was followed. Ascorbic acid was administered in clinical and subclinical cases even after cure considering its immunostimulatory and healing inducing effects. The recovery rate was faster in cases of clinical mastitis treated with ascorbic acid along with an intramammary infusion (group B) than the quarters of group C cows. Quarter wise the average duration/number (3.16${\pm}$0.11 days) of antimicrobial intramammary infusion was significantly (p<0.01) less in group B than that of average duration/number (5.33${\pm}$0.20 days) of group C. Subclinical mastitis cows treated with ascorbic acid showed 83.33% recovery while 16.77% did not respond to treatment till last day of study. Cows of group E (untreated) did not recovered from the mastitis. Subjective parameters viz. swelling, pain reflex of udder and physical changes in milk from quarter of ascorbic acid treated cows (group B) disappeared earlier than that of group C cows. It is concluded from this study that the ascorbic acid might be useful as an adjunct in case of clinical mastitis to get quick recovery with less number of intramammary infusions. High recovery rate in subclinical mastitis quarters of group D cows is appreciable and opens a new avenue to conduct further trials in a larger population in various field conditions. However, the pharmacology of ascorbic acid with particular reference to health of mammary gland needs to be investigated.
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Multi-response optimization for milling AISI 304 Stainless steel using GRA and DFA
Naresh, N.,Rajasekhar, K. Techno-Press 2016 Advances in materials research Vol.5 No.2
The objective of the present work is to optimize process parameters namely, cutting speed, feed rate, and depth of cut in milling of AISI 304 stainless steel. In this work, experiments were carried out as per the Taguchi experimental design and an $L_{27}$ orthogonal array was used to study the influence of various combinations of process parameters on surface roughness (Ra) and material removal rate (MRR). As a dynamic approach, the multiple response optimization was carried out using grey relational analysis (GRA) and desirability function analysis (DFA) for simultaneous evaluation. These two methods are considered in optimization, as both are multiple criteria evaluation and not much complicated. The optimum process parameters found to be cutting speed at 63 m/min, feed rate at 600 mm/min, and depth of cut at 0.8 mm. Analysis of variance (ANOVA) was employed to classify the significant parameters affecting the responses. The results indicate that depth of cut is the most significant parameter affecting multiple response characteristics of GFRP composites followed by feed rate and cutting speed. The experimental results for the optimal setting show that there is considerable improvement in the process.
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Role of Coflex as an Adjunct to Decompression for Symptomatic Lumbar Spinal Stenosis
Naresh Kumar,Siddarth M Shah,Yau Hong Ng,Vinodh Kumar Pannierselvam,Sudeep DasDe,Liang Shen 대한척추외과학회 2014 Asian Spine Journal Vol.8 No.2
Study design: Prospective cohort study. Purpose: To assess whether additional implantation of Coflex following spinal decompression provided better clinical outcomes compared to decompression alone for symptomatic lumbar spinal stenosis (LSS) and to determine whether improvement in clinical outcomes correlated with changes in the radiological indices studied. Overview of Literature: Literature on benefits of additional Coflex implantation compared to decompression alone for symptomatic LSS is limited. Methods: Patients with symptomatic LSS who met the study criteria were offered spinal decompression with Coflex implantation. Those patients who accepted Coflex implantation were placed in the Coflex group (n=22); while those opting for decompression alone, were placed in the comparison group (n=24). Clinical outcomes were assessed preoperatively, six-months, one-year and two-years postoperatively, using the Oswestry disability index, 100 mm visual analogue scale (VAS)-back pain and VAS-leg pain, and short form- 36 (SF-36). Radiological indices (disc height, foraminal height and sagittal angle) were assessed preoperatively, six months, one year, and two years postoperatively. Results: Both groups showed statistically significant (p <0.001) improvement in all the clinical outcome indicators at all points in time as compared to the preoperative status. However, improvement in the Coflex group was significantly greater (p <0.001) than the comparison group. Changes in the radiological indices did not correlate significantly with the improvement in clinical outcome indicators. Conclusions: Additional Coflex implantation after spinal decompression in symptomatic LSS offers better clinical outcomes than decompression alone in the short-term. Changes in radiological indices do not correlate with the improvements in clinical outcomes after surgery for symptomatic LSS.
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Green Chemistry Approach for the Synthesis of Gold Nanoparticles Using the Fungus Alternaria sp
( Naresh Niranjan Dhanasekar ),( Ganga Ravindran Rahu ),( Kannan Badri Narayanan ),( Gurusamy Raman ),( Natarajan Sakthive ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.7
The synthesis of gold nanoparticles has gained tremendous attention owing to their immense applications in the field of biomedical sciences. Although several chemical procedures are used for the synthesis of nanoparticles, the release of toxic and hazardous by-products restricts their use in biomedical applications. In the present investigation, gold nanoparticles were synthesized biologically using the culture filtrate of the filamentous fungus Alternaria sp. The culture filtrate of the fungus was exposed to three different concentrations of chloroaurate ions. In all cases, the gold ions were reduced to Au(0), leading to the formation of stable gold nanoparticles of variable sizes and shapes. UV-Vis spectroscopy analysis confirmed the formation of nanoparticles by reduction of Au3+ to Au0. TEM analysis revealed the presence of spherical, rod, square, pentagonal, and hexagonal morphologies for 1 mM chloroaurate solution. However, quasi-spherical and spherical nanoparticles/heart-like morphologies with size range of about 7-13 and 15-18 nm were observed for lower molar concentrations of 0.3 and 0.5 mM gold chloride solution, respectively. The XRD spectrum revealed the face-centered cubic crystals of synthesized gold nanoparticles. FT-IR spectroscopy analysis confirmed the presence of aromatic primary amines, and the additional SPR bands at 290 and 230 nm further suggested that the presence of amino acids such as tryptophan/tyrosine or phenylalanine acts as the capping agent on the synthesized mycogenic gold nanoparticles.
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Naresh Gurajarapu,V. Naga Bhushana Rao,I. N. Niranjan Kumar 보안공학연구지원센터 2014 International Journal of u- and e- Service, Scienc Vol.7 No.6
Turbine blades are considered to be the heart of turbine and play a vital role in extracting energy from high temperature and high pressure gases. Without blades there would be no power and the slightest fault in blading would mean a reduction in efficiency and costly repairs. In this regard, an attempt has been made to analyze the failed marine gas turbine blade. Static structural and Steady state thermal analyses have been analyzed using ANSYS 14.5 to predict the probable conditions which leads blade failure. To investigate the causes of high pressure temperature (HPT) turbine blade failures, a turbine blade of 30 MW gas turbine engine intended for operation onboard ship has been considered for the analysis. Before failure, this gas turbine blade was operated for about 10000 hours while its service life was expected to be around 15000 hours. To improve the life time of a blade, prediction of failure criteria has been analyzed. In addition, a comparative analysis has also been made to determine the strength and suitability of a HPT blade made of Nickel based super alloy X under examination. This material has been compared with other two materials such as Nimonic alloy 80A and Inconel 625. Based on the results of comparative study, it is concluded that Nickel based super alloy X can be a suitable material for the manufacturing of gas turbine blades.
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Naresh, R.,Dwivedi, S.K.,Dey, S.,Swarup, D. Asian Australasian Association of Animal Productio 2001 Animal Bioscience Vol.14 No.4
A study was undertaken to record the utilization of some micro-elements during inflammation of the mammary gland. Two groups of twenty five animals each suffering from subclinical and clinical mastitis were selected for the study. All the animals were maintained on identical diets. Blood zinc level in cows with subclinical mastitis ($5.66{\pm}0.52$) was significantly (p<0.05) lower than that of healthy cows ($8.46{\pm}1.10ppm$). No significant difference was, however, recorded in blood copper and cobalt levels between healthy and mastitic cows.
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( Naresh Singhal ),( Anthea Johnson ) 대한상하수도학회 2006 공동춘계 학술발표회 논문집 Vol.2006 No.-
Rapid urbanisation in Auckland, and other urban parts of New Zealand, has resulted in increased generation of stormwater containing dissolved pollutants such as heavy metals and synthetic organics, which can be difficult to remove in conventional filters. In addition, the accumulation of contaminants can lead to decreased filter performance. Bioretention systems may offer a solution. These systems generally consist of an engineered permeable soil with specific vegetation and associated microorganisms. During a storm event, runoff entering the bioretention system infiltrates the soil, where sediments and dissolved pollutants are retained. In the period between rain events, contaminants are mobilized by compounds produced by plants and bacteria. Subsequently, plants can take up the dissolved contaminants via their root network. Additionally, pollutants can be degraded by plants and the associated microbial communities in the rhizosphere. Plant matter can be regularly harvested for disposal. While the design and implementation of such systems appear to be simple, this simplicity is deceptive as suggested by the variable and often poor performance of such systems in practice. The processes occurring in the rhizosphere are varied and complex. This paper presents a review of the processes occurring in a stormwater bioretention system with the objective of motivating discussion on ways to improve the performance of such systems.
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Naresh Dangi,Un Taek Lim 한국응용곤충학회 2015 한국응용곤충학회 학술대회논문집 Vol.2015 No.04
Lethal concentration of Beauveria bassiana (Strain GHA, Botanigard, Arysta LifeScience) against Riptortus pedestris (F.) (Hemiptera: Alydidae) was compared with that of its’ parasitoid Ooencyrtus nezarae Ishii (Hymenoptera: Encyrtidae). Five concentrations of the mycoinsecticide, i.e., 5×108, 1×108, 2×107, 4×106, and 8×105 conidia/ml, were used. Glass scintillation vial was coated with 100 μl solution, and insects were released and assessed up to 12 hours. The LC50 and LC20 of second instar R. pedestris were 1.8×1010 and 1.5×108 conidia/ml, and those of O. nezarae were 1.9×107 and 2.8×106 conidia/ml, respectively. The mortality of O. nezarae was observed 3.9 times higher than R. pedestris in higher concentration. This result shows that O. nezarae is more susceptible to the mycoinsecticide than R. pedestris.
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