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Minkyoung Shin,Jungsoon Choi,Munkhtsetseg Luvsan J-INSTITUTE 2022 International Journal of Human & Disaster Vol.7 No.1
Purpose: In the present time, the interest in looks has rapidly increased regardless of gender and age, and we are living through the age of priority over looks. An individual s looks is not merely a simple caring, but has also become a social competitiveness, which increases the interest in looks and enhances the body image and self-esteem. The purpose of this study is to examine and understand the effect of the body image and the interest in looks perceived by female college students on the empathy of overcoming disaster targeting the female college students. Method: As for the research method, a questionnaire was used targeting female college students in Seoul, Gyeonggi, Incheon, and other areas. The questionnaire was consisted of body image, interest in looks, and interpersonal variables, while the frequency analysis was performed to examine the general characteristics of the re-search subjects, and the multiple regression analysis was performed to examine the interpersonal relationship between the body image and the interest in looks. Results: First, in terms of the effect of the female college student s body image on the empathy of overcoming disaster, it turned out that among the body images, the interest in looks turned out to have an effect on cognitive empathy, emotional empathy, and attitude empathy, and among the body images, the body satisfaction turned out to have effect on the emotional empathy and attitude empathy. Second, in terms of the effect of the female college student s body image on the empathy of overcoming disaster, aesthetic orientation turned to have effect on the cognitive empathy, emotional empathy, and the attitude empathy among the interest in looks, and self-expression among the interest in looks turned out to affect the emotional empathy only. Conclusion: Given the current ‘COVID-19’ crisis, many problems have ravaged the world, and as disasters pro-long, the interest in overcoming disasters has also grown. At the same time, the interest in looks is rapidly increasing due to the priority over looks. Hence, this study has examined the effect of body image and interest in looks perceived by the female college students on the empathy of overcoming disaster, and recognizes the importance of empathy for the interest in looks, and hence, more research would be required.
Epigenetic modulation of the muscarinic type 3 receptor in salivary epithelial cells.
Shin, Yong-Hwan,Jin, Meihong,Hwang, Sung-Min,Choi, Seul-Ki,Namkoong, Eun,Kim, Minkyoung,Park, Moon-Yong,Choi, Se-Young,Lee, Jong-Ho,Park, Kyungpyo United States and Canadian Academy of Pathology [e 2015 Laboratory investigation Vol.95 No.2
<P>Muscarinic receptors, particularly the type 3 subtype (M3R), have an important role in exocrine secretion. M3R normally function in HSG cells originated from human submandibular gland ducts, but not in A253 and SGT cells, derived from human submandibular carcinoma and salivary gland adenocarcinoma. However, the underlying mechanism of this suppression has remained elusive. In this study, we examined whether M3R function is suppressed by epigenetic modulation of the receptor. To this end, we investigated the mRNA transcript and protein levels of the M3R using reverse transcriptase-PCR, western blot, and confocal microscopy analyses. Global DNA methylation assays, methylation-specific PCR, and bisulfite sequencing were also performed to understand the epigenetic status of the M3R CpG island. We found that A253 cells expressed all subtypes of muscarinic receptors, except M3R, on the mRNA level. However, treatment of cells with 5-aza-2'-deoxycytidine (5-Aza-CdR), a DNA-demethylating agent, increased the expression levels of both M3R mRNA transcript and protein in proportion to the incubation period. 5-Aza-CdR completely restored the carbachol-induced calcium response, which was not observed in untreated A253 cells. In untreated A253 cells, all CG pairs from the 1st to 14th were methylated and 5-Aza-CdR treatment demethylated one of the methylated CG pairs. We also examined the methylation pattern of M3R CpG island in human cancer tissue. Interestingly, the result was very similar to those of A253 cells. All CG pairs in M3R CpG island were also methylated. Another salivary gland tumor cell line, SGT, also showed the similar methylation pattern, heavy methylation in M3R CpG island. It is concluded that CpG island in M3R is hypermethylated in cancer cell lines and human cancer. Our results further suggest that 5-Aza-CdR could potentially be used to restore the function of M3R, suppressed in some cancer cell types.</P>
정민경(Minkyoung Jeong),권용석(Yongseok Kwon),전동근(Dongkeun Jun),이명철(Myungchul Lee),김지남(Jeenam Kim),신동혁(Donghyeok Shin),김완섭(Wan-seop Kim),최현곤(Hyungon Choi) 대한두경부종양학회 2021 대한두경부 종양학회지 Vol.37 No.1
Intraosseous hemangioma is a rare, benign vascular tumor of endothelial origin. It accounts for fewer than 1% of all hemangiomas, and very rarely occurs in the face. Intraosseous hemangioma usually presents as an asymptomatic lesion, but symptoms can occur due to the mass effect. The authors describe a case of intraosseous hemangioma of the zygoma with a review of the relevant literature. A 44-year-old man presented with a chief complaint of painless swelling on the left zygomatic region that had been slowly growing for the past year. On physical examination, a hard, non-movable mass in a deep layer was palpated. On computed tomography performed to evaluate its layers and extent, trabeculation was found inside the mass, but the lack of destruction of the surrounding bone suggested that the mass was benign. Complete surgical excision was performed under local anesthesia. After complete excision of the mass, slight erosions remained on the cortical bone of the zygoma, but because it was small enough not to cause a facial deformity such as depression or asymmetry, no additional reconstructive procedure was performed. There were no symptoms or recurrence during a 8-month follow-up period.
우리나라 구강건강 의료의 질 지표 개발을 위한 기초연구
신호성(Hosung Shin),김민경(Minkyoung Kim),김보라(Bo-Ra Kim) 대한치과의사협회 2022 대한치과의사협회지 Vol.60 No.11
The aims of this study were to evaluate quality indicators that can be applied to the dental care delivery system in Korea. This study was performed with a three-step process. Firstly, authors searched for quality indicators developed in dentistry field. Among them, 80 quality indicators were selected as the indicators that used in dental institutions, and then 33-item preliminary list was extracted through evaluation by 9 experts consisted of dental clinicians and professors (college of dentistry and department of dental hygiene). Based on this 33-item preliminary list, a Delphi process was conducted twice by a stakeholder group consisting of 17 panels (dentists, dental hygienists, dental technicians, professors of dental colleges, and dental hygiene professors). Each item of the preliminary list was classified into 5 domains of importance, relevance, feasibility, reliability, and sensitivity. The panels were asked to rate from 0 to 3-point (very unnecessary - very appropriate) to the 5 domains of all items. As a result, the sealant treatment item received the most consent, and the item of whether unnecessary antibiotics is prescribed received the lowest preference. Among the 33 items, the items that received a score of 2.5 or higher were sealant, brushing, fluoride application, caries prevention, periodontal management, regular check-up, continuity of treatment, and evaluation of current symptoms. This study was performed as basic research. Based on international consensus on the definition of the quality of oral health care, development of new measures is necessary to produce quality indicators that suitable for the dental setting in Korea.