Height Effect could be a Factor for the Musculoskeletal Disorder in Cleaning Occupation

( Ming Hsu Wang ),( Wen Ko Chiou ),( Bi Hui Chen ) 한국감성과학회 2014 춘계학술대회 Vol.2014 No.-

Clearly, cleaning is a demanding repetitive occupation, which incurs a high level of musculoskeletal disorders. The phrase work-related upper limb musculoskeletal disorders includes a variety of upper limb degenerative and inflammatory diseases and disorders, which result in pain and functional impairment. Inappropriate and poor working postures, lack of task variation, poor ergonomic design of work places, poor design of cleaning tools and work organization (e.g., long working hours, low salaries and awkward schedules) are all areas where relatively simple interventions can significantly reduce the rate of exposure to occupational disease. The poor working resources make the high rate of related musculoskeletal disorders for the cleaners. The aim of this study was to compare the musculoskeletal disorders with different height of the cleaners and to evaluate the effect of height on cleaners`working postures in a school environment. Thirty motivated professional female cleaners from one university in Taiwan took part in this survey. Their age ranged from 45 to 65 years and the average length of their work experience was 6.5 years. The survey was carried out according to the following steps: Step 1: Definition of the framework/theme of the survey. Step2: Establishment of the goal, Step3: Nordic Musculoskeletal Questionnaire (NMQ) survey, Step4: Development of a cleaning task analysis, Step5: Rapid Entire Body Assessment (REBA) survey, Step6: Evaluation for NMQ and REBA.

Height effect could be a factor for the musculoskeletal disorder in cleaning occupation

Ming-Hsu Wang,Wen-Ko Chiou,Bi-Hui Chen 대한인간공학회 2014 대한인간공학회 학술대회논문집 Vol.2014 No.5

Clearly, cleaning is a demanding repetitive occupation, which incurs a high level of musculoskeletal disorders. The phrase “work-related upper limb musculoskeletal disorders” includes a variety of upper limb degenerative and inflammatory diseases and disorders, which result in pain and functional impairment. Inappropriate and poor working postures, lack of task variation, poor ergonomic design of work places, poor design of cleaning tools and work organization (e.g., long working hours, low salaries and awkward schedules) are all areas where relatively simple interventions can significantly reduce the rate of exposure to occupational disease. The poor working resources make the high rate of related musculoskeletal disorders for the cleaners. The aim of this study was to compare the musculoskeletal disorders with different height of the cleaners and to evaluate the effect of height on cleaners’ working postures in a school environment. Thirty motivated professional female cleaners from one university in Taiwan took part in this survey. Their age ranged from 45 to 65 years and the average length of their work experience was 6.5 years. The survey was carried out according to the following steps: Step 1: Definition of the framework/theme of the survey. Step2: Establishment of the goal, Step3: Nordic Musculoskeletal Questionnaire (NMQ) survey, Step4: Development of a cleaning task analysis, Step5: Rapid Entire Body Assessment (REBA) survey, Step6: Evaluation for NMQ and REBA. Base on this research result, it can be concluded that different heights with the cleaners can lead to different musculoskeletal disorders and base on the different heights could provide the different protection devices and recommendations which, in turn, leads to the cleaners’ better health and better cleaning results.

Antiproliferative and Antitumorigenic Activity of Toona sinensis Leaf Extracts in Lung Adenocarcinoma

Chih-Jen Yang,Yu-Jung Huang,Cheng-Yuan Wang,Chuan-Sheng Wang,Pei-Hui Wang,Jen-Yu Hung,Tung-Heng Wang,Hseng-Kuang Hsu,Hurng-Wern Huang,S.P. Anand Kumar,Ming-Shyan Huang,Ching-Feng Weng 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.1

Toona sinensis is a traditional Chinese herb, and the extracts of T. sinensis leaf possess a variety of biological functions. This study attempted to test the antiproliferative effect of TSL-1 (a bioactive fraction of T. sinensis) in H441 cells (lung adenocarcinoma). The data showed that the antiproliferative effect of TSL-1 on H441 cells is prominent using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. TSL-1-induced apoptosis was confirmed by cell morphology, sub-G1 peak accumulation, cleavage of poly(ADP)-ribose polymerase, and propidium iodide-annexin V double staining. Furthermore, decreased Bcl-2 accompanied by increased Bax (in western blotting) was found with TSL-1 treatment of H441 cells. TSL-1 treatment-induced G1 arrest was concurrent with the down-regulation of protein levels of cyclin D1 and cyclin-dependent kinase 4 in H441 cells. Peroral and intraperitoneal administrations of TSL-1 were performed to evaluate the therapeutic efficacy, and peroral administration of TSL-1 was also used to elucidate the therapeutic efficacy in the H441 cell xenograft model in vivo. The data revealed that TSL-1 treatment inhibited H441 tumor growth in both therapeutic and preventive experiments. Taken together, these results demonstrate that TSL-1 possesses the capability of preventing and alleviating lung cancer proliferation in vitro and in vivo with proven nephrological and hepatic safety and has the potential to be developed as an anti–lung cancer drug.

Epidemiological trend in inflammatory bowel disease in Taiwan from 2001 to 2015: a nationwide population-based study

Hsu-Heng Yen,Meng-Tzu Weng,Chien-Chih Tung,Yu-Ting Wang,Yuan Ting Chang,Chin-Hao Chang,Ming-Jium Shieh,Jau-Min Wong,Shu-Chen Wei 대한장연구학회 2019 Intestinal Research Vol.17 No.1

Background/Aims: Incidences of inflammatory bowel disease (IBD), ulcerative colitis (UC), and Crohn’s disease (CD), havebeen increasing in Asia. In this study, we report the relevant clinical characteristics and determined the epidemiological trend ofIBD in Taiwan from 2001 to 2015. Methods: A retrospective study was conducted to analyze data recorded from January 2001through December 2015 in the registered database compiled by the National Health Insurance and provided by the Ministry ofHealth and Welfare, Taiwan. Results: A total of 3,806 patients with catastrophic IBD illness were registered from 2001 to 2015 inTaiwan (CD, 919; UC, 2,887). The crude incidence of CD increased from 0.17/100,000 in 2001 to 0.47/100,000 in 2015, whereasthat of UC increased from 0.54/100,000 in 2001 to 0.95/100,000 in 2015. The prevalence of CD increased from 0.6/100,000 in2001 to 3.9/100,000 in 2015, whereas that of UC increased from 2.1/100,000 in 2001 to 12.8/100,000 in 2015. The male-to-femaleratio in the study sample was 2.19 for CD and 1.62 for UC. The median age of those registered with CD was lower than that ofthose registered for UC: 38.86 and 44.86 years, respectively. A significantly greater increase in CD incidence rate was identifiedamong 20 to 39-year-old compared with other age groups. Conclusions: Using Taiwan’s nationwide insurance database, we determinedthat the number of patients with CD increased more rapidly during the study period than the number of patients withUC, especially among age 20 to 39-year-old, resulting in a decreased UC-to-CD ratio. (Intest Res 2019;17:54-62)

Effective Decomposing Approach for Historical XML Documents

Ming Shien Cheng,PingYu Hsu,MinTzu Wang 보안공학연구지원센터 2012 International Journal of Control and Automation Vol.5 No.3

Implementation of point-of-care platforms for rapid detection of porcine circovirus type 2

Chiao-Hsu Ke,Mao-Yuan Du,Wang-Ju Hsieh,Chiu-Chiao Lin,James Mingjuh Ting,Ming-Tang Chiou,Chao-Nan Lin The Korean Society of Veterinary Science 2024 Journal of Veterinary Science Vol.25 No.2

Background: Porcine circovirus type 2 (PCV2) infection is ubiquitous around the world. Diagnosis of the porcine circovirus-associated disease requires clinic-pathological elements together with the quantification of viral loads. Furthermore, given pig farms in regions lacking access to sufficient laboratory equipment, developing diagnostic devices with high accuracy, accessibility, and affordability is a necessity. Objectives: This study aims to investigate two newly developed diagnostic tools that may satisfy these criteria. Methods: We collected 250 specimens, including 170 PCV2-positive and 80 PCV2-negative samples. The standard diagnosis and cycle threshold (Ct) values were determined by quantitative polymerase chain reaction (qPCR). Then, two point-of-care (POC) diagnostic platforms, convective polymerase chain reaction (cPCR, qualitative assay: positive or negative results are shown) and EZtargex (quantitative assay: Ct values are shown), were examined and analyzed. Results: The sensitivity and specificity of cPCR were 88.23% and 100%, respectively; the sensitivity and specificity of EZtargex were 87.65% and 100%, respectively. These assays also showed excellent concordance compared with the qPCR assay (κ = 0.828 for cPCR and κ = 0.820 for EZtargex). The statistical analysis showed a great diagnostic power of the EZtargex assay to discriminate between samples with different levels of positivity. Conclusions: The two point-of-care diagnostic platforms are accurate, rapid, convenient and require little training for PCV2 diagnosis. These POC platforms can discriminate viral loads to predict the clinical status of the animals. The current study provided evidence that these diagnostics were applicable with high sensitivity and specificity in the diagnosis of PCV2 infection in the field.

Combined Assessment of Serum Alpha-Synuclein and Rab35 is a Better Biomarker for Parkinson’s Disease

Hung-Li Wang,Chin-Song Lu,Tu-Hsueh Yeh,Yu-Ming Shen,Yi-Hsin Weng,Ying-Zu Huang,Rou-Shayn Chen,Yu-Chuan Liu,Yi-Chuan Cheng,Hsiu-Chen Chang,Ying-Ling Chen,Yu-Jie Chen,Yan-Wei Lin,Chia Chen Hsu,Huang-Li 대한신경과학회 2019 Journal of Clinical Neurology Vol.15 No.4

Background and Purpose It is essential to develop a reliable predictive serum biomarker for Parkinson’s disease (PD). Te accumulation of alpha-synuclein (αSyn) and up-regulated expression of Rab35 participate in the etiology of PD. Te purpose of this investigation was to determine whether the combined assessment of serum αSyn and Rab35 is a useful predictive biomarker for PD. Methods Serum levels of αSyn or Rab35 were determined in serum samples from 59 sporadic PD patients, 19 progressive supranuclear palsy (PSP) patients, 20 multiple system atrophy (MSA) patients, and 60 normal controls (NC). Receiver operating characteristics (ROC) curves were calculated to determine the diagnostic accuracy of αSyn or/and Rab35 in discriminating PD patients from NC or atypical parkinsonian patients. Results The levels of αSyn and Rab35 were increased in PD patients. The serum level of Rab35 was positively correlated with that of αSyn in PD patients. Compared to analyzing αSyn or Rab35 alone, the combined analysis of αSyn and Rab35 produced a larger area under the ROC curve and performed better in discriminating PD patients from NC, MSA patients, or PSP patients. When age was dichotomized at 55, 60, 65, or 70 years, the combined assessment of αSyn and Rab35 for classifying PD was better in the group below the cutof age than in the group above the cutof age. Conclusions Combined assessment of serum αSyn and Rab35 is a better biomarker for discriminating PD patients from NC or atypical parkinsonian patients, and is a useful predictive biomarker for younger sporadic PD patients.

Threshold magnetoresistance in anistropic magnetic 2D transition metal dichalcogenides

Xu, Hongjun,Hsu, Ming-Chien,Fuh, Huei-Ru,Feng, Jiafeng,Han, Xiufeng,Zhao, Yanfeng,Zhang, Duan,Wang, Xinming,Liu, Fang,Liu, Huajun,Cho, Jiung,Choi, Miri,Chun, Byong Sun,Ó,Coileá,in, Cormac The Royal Society of Chemistry 2018 Journal of Materials Chemistry C Vol.6 No.12

<P>Recently many novel magnetoresistance (MR) phenomena have been reported from studies of two dimensional (2D) materials. Here, we report on the exotic transport behavior of VS2. A large negative and quadratic MR of −10% is observed for an in-plane magnetic field B up to 14 T. Remarkably, when the applied field deviates from the in-plane orientation there is a threshold field, Bc, and the MR shows a plateau of near zero MR. When B < Bc, only a single state exists and the transition between quantum spin states is forbidden. Our work sheds new light on the MR of magnetic 2D materials with localized states and may spur further investigations.</P>

Hypoglycemia Revisited in the Acute Care Setting

Shih-Hung Tsai,Der-Ming Chu,Yen-Yue Lin,Chin-Wang Hsu,Chien-Sheng Cheng 연세대학교의과대학 2011 Yonsei medical journal Vol.52 No.6

Hypoglycemia is a common finding in both daily clinical practice and acute care settings. The causes of severe hypoglycemia (SH) are multi-factorial and the major etiologies are iatrogenic, infectious diseases with sepsis and tumor or autoimmune diseases. With the advent of aggressive lowering of HbA1c values to achieve optimal glycemic control, patients are at increased risk of hypoglycemic episodes. Iatrogenic hypoglycemia can cause recurrent morbidity, sometime irreversible neurologic complications and even death, and further preclude maintenance of euglycemia over a lifetime of diabetes. Recent studies have shown that hypoglycemia is associated with adverse outcomes in many acute illnesses. In addition, hypoglycemia is associated with increased mortality among elderly and non-diabetic hospitalized patients. Clinicians should have high clinical suspicion of subtle symptoms of hypoglycemia and provide prompt treatment. Clinicians should know that hypoglycemia is associated with considerable adverse outcomes in many acute critical illnesses. In order to reduce hypoglycemia-associated morbidity and mortality, timely health education programs and close monitoring should be applied to those diabetic patients presenting to the Emergency Department with SH. ED disposition strategies should be further validated and justified to achieve balance between the benefits of euglycemia and the risks of SH. We discuss relevant issues regarding hypoglycemia in emergency and critical care settings.

Apply the combination of anthropometric health indicators and Sheldon`s somatotype in health promotion

Wen-Ko Chiou,Ming-Hsu Wang,Bi-Hui Chen 대한인간공학회 2014 대한인간공학회 학술대회논문집 Vol.2014 No.5

The concept of somatotyping is a unique method for the classification of human physique that was first invented by Sheldon and modified by Heath and Carter. Somatotype is also widely used as a tool to estimate the nutritional status of populations and to monitor the growth and diseases of individuals. Human bodies compose from many parts and it is difficult to judge the healthy status from the single index. The body image compose form the multiple indexes could help people to judge the healthy status from the anthropometry data. The aim of this study was to develop body image templates in both genders from the 3D anthropometry data to evaluate the human healthy status. This study collected the dimensions from anthropometry and body image among 90 Taiwanese participants in the Keelung Chang Gung Memorial Hospital, Taiwan. This research uses the 3D whole body photography system to collect the anthropometry dimensions and analyze the data from the Beauty3D software. Collecting the 5 indexes, including body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR), waist-height ratio (WHtR) and waist-thigh ratio (WTR) and to judge the indexes for normal and abnormal status by the WHO standards. Using the multiple indexes to category the body health into 4 levels. The results show that 4 body image templates in both genders were created, and the difference between the different templates and genders were discovered. The body image templates showed the human body images come from the different health status. It can be concluded that different body image templates from the multiple dimensions can lead to judge the human healthy status and base on the different templates could provide the visual judgment for the different body types for the health status.