Bioprocess Production of Sea Cucumber Rice Wine and Characterization of Functional Components and Antioxidant Activities

Shuai He,Lin Wang,Hao Dong,Pei Liu,Peiyu Shi,Xuemin Li,Xingchen Ren,Ning Lv,Yanan Liu,Changhu Xue,Hong Lin,Xiangzhao Mao 한국식품과학회 2014 Food Science and Biotechnology Vol.23 No.3

A new production bioprocess for sea cucumberrice wine (SCRW) was established. The traditional productiontechnology of Chinese rice wine was combined with additionof sea cucumber hydrosylates. The optimal enzymaticconditions of sea cucumber and the fermentation process ofSCRW were determined. The weight of sea cucumberenzymatic hydrolysates was 2.5% of millet while cookingthe millet. SCRW contained abundant free amino acids (30total at 1,681.216 mg/L), oligosaccharides (4 total at10,999.380 mg/L), total phenols (658.850 mg/L), andmineral elements (9 total at 1,911.353 mg/kg), and anantioxidant activity, all of which were higher than forcontrol rice wine (CRW). Galactosamine and glucuronicacid, both sea cucumber polysaccharides, were present inSCRW, but not in CRW.

Friction and Wear of Self-mated SiC and Si3N4 in Green Water-based Lubricant

Shuai Yan,Bin Lin,Feng Liu,Fugang Yan 한국정밀공학회 2012 International Journal of Precision Engineering and Vol. No.

Hydrostatic/hybrid bearings have been used in many engineering applications. In order to address the disadvantages of lubricating oil such as pollution and resource consumption, researchers are trying to use water to replace oil in these bearings. To eliminate the corrosivity of water and increase its viscosity, additives were added in water and this new lubricant is called “green water-based lubricant”. Ceramics are considered to be very suitable tribo-pair materials in water. In order to select the best material in the green water-based lubricant and explore the effect of the additives, this paper carried out friction and wear experiments of self-mated SiC and self-mated Si3N4 in this new lubricant on a ring-toring tribometer. The results show that self-mated SiC possesses better running-in property, higher load-carrying capacity,lower friction coefficient, lower wear rate and smoother surface topography. The results show that the self-mated SiC and green water-based lubricant is a promising combination to replace the metal/oil system in hydrostatic/hybrid bearings.

RESEARCH ON THE INFLUENCE OF HYDROGEN AND OXYGEN FUEL OBTAINED FROM WATER ELECTROLYSIS ON COMBUSTION STABILITY OF SHALE GAS ENGINES

Liu Shuai,Wang Zhong,Jia He Kun,Chen Lin 한국자동차공학회 2019 International journal of automotive technology Vol.20 No.1

Hydrogen and oxygen fuel obtained from water electrolysis mainly contains H2 and O2, usually abbreviated to HHO. The compositional characteristics of HHO were analyzed by gas chromatography-mass spectrometry (GC-MS). The influence of HHO on the combustion process in the cylinder was discussed. The change law of the maximum combustion pressure and the variation of the crank angle were studied, and the nonlinear dynamic process of the combustion process was revealed. The research indicated that the cylinder pressure increased after mixing HHO and that the period of flame development and rapid combustion was shortened. With the increase in HHO content, the cycle-by-cycle variations were reduced, combustion stability improved, partial-burning and other abnormal combustion phenomena improved, the phase space trajectory distribution gradually intensified, and the engine combustion process of the cyclical variation increased.

An effective health indicator based on two dimensional hidden Markov model

Lin Li,Tingfeng Ming,Shuyong Liu,Shuai Zhang 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.4

It is still a great challenge to find an effective degradation indication for health degradation assessment. For that purpose, many computational algorithms have been motivated or suggested. These algorithms commonly use the multiple statistic-based features obtained through calculating the vibration signal to build health indicator which does not consider the internal relevancy among the features. For the purpose of building an effective degradation indicator with pronounced tendency, a novel method is proposed. With the ability of keeping the local structure of data set, Locality preserving projections (LPP) is used to reduce the dimension of the general feature set with the main information remained. Since 2-Dimensional Hidden Markov model (2-D HMM) not only take the relevance between the individuals of fault features into consideration but also capture the global characteristics of the multiple features, 2-D HMM based negative log likelihood probability is built as a new degradation index. The experimental results indicate that the proposed indicator show great abilities to make degradation performance of the bearing and is sensitive to weak defects.

Active control of amplitude and phase of high-power RF systems in EAST ICRF heating experiments

Zhu Guanghui,Liu Lunan,Mao Yuzhou,Zhang Xinjun,Guo Yaoyao,Ai Lin,Jiang Runhao,Qin Chengming,Zhang Wei,Yang Hua,Yuan Shuai,Wang Lei,Ju Songqing,Wang Yongsheng,Sun Xuan,Yang Zhida,Wang Jinxin,Cheng Yan 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.2

The EAST ICRF system operating space has been extended in power and phase control with a low-level RF system for the new double-strap antenna. Then the multi-step power and periodic phase scanning experiment were conducted in L-mode plasma, respectively. In the power scanning experiment, the stored energy, radiation power, plasma impedance and the antenna's temperature all have positive responses during the short ramp-ups of PL;ICRF. The core ion temperature increased from 1 keV to 1.5 keV and the core heating area expanded from jZj 5 cmto jZj 10 cm during the injection of ICRF waves. In the phasing scanning experiment, in addition to the same conclusions as the previous relatively phasing scanning experiment, the superposition effect of the fluctuation of stored energy, radiation power and neutron yield caused by phasing change with dual antenna, resulting in the amplitude and phase shift, was also observed. The active control of RF output facilitates the precise control of plasma profiles and greatly benefits future experimental exploration.

Induction Chemotherapy Plus Concurrent Chemoradiotherapy versus Concurrent Chemoradiotherapy Alone in Locoregionally Advanced Nasopharyngeal Carcinoma in Children and Adolescents: A Matched Cohort Analysis

Yang Li,Lin-Quan Tang,Li-Ting Liu,Shan-Shan Guo,Yu-Jing Liang,Xue-Song Sun,Qing-Nan Tang,Jin-Xin Bei,Jing Tan,Shuai Chen,Jun Ma,Chong Zhao,Qiu-Yan Chen,Hai-Qiang Mai 대한암학회 2018 Cancer Research and Treatment Vol.50 No.4

Purpose The purpose of this study was to evaluate the long-term clinical outcome and toxicity of induction chemotherapy (IC) followed by concomitant chemoradiotherapy (CCRT) compared with CCRT alone for the treatment of children and adolescent locoregionally advanced nasopharyngeal carcinoma (LACANPC). Materials and Methods A total of 194 locoregionally advanced nasopharyngeal carcinoma patients younger than 21 years who received CCRT with or without IC before were included in the study population. Overall survival (OS) rate, progression-free survival (PFS) rate, locoregional recurrence-free survival (LRFS) rate, and distant metastasis-free survival (DMFS) rate were assessed by the Kaplan-Meier method and a log-rank test. Treatment toxicities were clarified and compared between two groups. Results One hundred and thiry of 194 patients received IC+CCRT. Patients who were younger and with more advanced TNM stage were more likely to receive IC+CCRT and intensive modulated radiotherapy. The addition of IC before CCRT failed to improve survival significantly. The matched analysis identified 43 well-balanced patients in both two groups. With a median follow-up of 51.5 months, no differences were found between the IC+CCRT group and the CCRT group in 5-year OS (83.7% vs. 74.6%, p=0.153), PFS (79.2% vs. 73.4%, p=0.355), LRFS (97.7% vs. 88.2%, p=0.083), and DMFS (81.6% vs. 81.6%, p=0.860). N3 was an independent prognostic factor predicting poorer OS, PFS, and DMFS. The addition of IC was associated with increased rates of grade 3 to 4 neutropenia. Conclusion This study failed to demonstrate that adding IC before CCRT could provide a significant additional survival benefit for LACANPC patients. Further investigations are warranted.

Physiological response of red macroalgae Pyropia yezoensis (Bangiales, Rhodophyta) to light quality: a short-term adaptation

Xuefeng Zhong,Shuai Che,Congying Xie,Lan Wu,Xinyu Zhang,Lin Tian,Chan Liu,Hongbo Li,Guoying Du The Korean Society of Phycology 2023 ALGAE Vol.38 No.2

Light quality is a common environmental factor which influences the metabolism of biochemical substances in algae and leads to the response of algal growth and development. Pyropia yezoensis is a kind of economic macroalgae that naturally grows in the intertidal zone where the light environment changes dramatically. In the present study, P. yezoensis thalli were treated under white light (control) and monochromatic lights with primary colors (blue, green, and red) for 14 days to explore their physiological response to light quality. During the first 3 days of treatment, P. yezoensis grew faster under blue light than other light qualities. In the next 11 days, it showed better adaptation to green light, with higher growth rate and photosynthetic capacity (reflected by a higher rETR_max = 61.58 and E_k = 237.78). A higher non-photochemical quenching was observed in the treatment of red light than others for 14 days. Furthermore, the response of P. yezoensis to light quality also results in the difference of photosynthetic pigment contents. The monochromatic light could reduce the synthesis of all pigments, but the reduction degree was different, which may relate to the spectral absorption characteristics of pigments. It was speculated that P. yezoensis adapted to a specific or changing light environments by regulating the synthesis of pigments to achieve the best use of light energy in photosynthesis and premium growth and metabolism.

The Prognostic Value of Treatment-Related Lymphopenia in Nasopharyngeal Carcinoma Patients

Li-Ting Liu,Qiu-Yan Chen,Lin-Quan Tang,Shan-Shan Guo,Ling Guo,Hao-Yuan Mo,Ming-Yuan Chen,Chong Zhao,Xiang Guo,Chao-Nan Qian,Mu-Sheng Zeng,Jin-Xin Bei,Jing Tan,Shuai Chen,Ming-Huang Hong,Jian-Yong Shao 대한암학회 2018 Cancer Research and Treatment Vol.50 No.1

Purpose This study was conducted to evaluate the prognostic value of treatment-related lymphopenia in patients with nasopharyngeal carcinoma (NPC). Materials and Methods A total of 413 consecutive stage II-IVb NPC patients treated with concurrent chemoradiotherapy (CCRT) were enrolled. The overall survival (OS), progression-free survival (PFS), and distant metastasis-free survival (DMFS) were calculated with the Kaplan-Meier method, and differences were compared using the log-rank test. Results A minimum (mini)–absolute lymphocyte counts (ALC) of < 390 cells/μL or ALC after 3 months of CCRT (post3m-ALC) < 705 cells/μL was significantly associated with worse outcome than mini-ALC ! 390 cells/μL (OS, p=0.002; PFS, p=0.005; DMFS, p=0.004) or post3m-ALC ! 705 cells/μL (OS, p < 0.001; PFS, p < 0.001; DMFS, p=0.001). Patients with lymphopenia (mini-ALC < 390 cells/μL and post3m-ALC < 705 cells/μL) had a worse prognosis than those without lymphopenia (mini-ALC ! 390 cells/μL and post3m-ALC ! 705 cells/μL) (OS, p < 0.001; PFS, p < 0.001; DMFS, p < 0.001). Multivariate analysis revealed that post3m-ALC was an independent prognostic factor for OS (hazard ratio [HR], 1.76; 95% confidence interval [CI], 1.12 to 2.78; p=0.015), PFS (HR, 1.86; 95% CI, 1.23 to 2.82; p=0.003), and DMFS (HR, 1.87; 95% CI, 1.13 to 3.08; p=0.014). Multivariate analysis also revealed that patients with lymphopenia had a high risk of death (HR, 3.79; 95% CI, 1.75 to 8.19; p=0.001), disease progression (HR, 2.93; 95% CI, 1.59 to 5.41; p=0.001), and distant metastasis (HR, 3.89; 95% CI, 1.67 to 9.10; p=0.002). Multivariate analysis performed with time dependent Cox regression demonstrated ALC was an independent prognostic factor for OS (HR, 0.995; 95% CI, 0.991 to 0.999; p=0.025) and PFS (HR, 0.993; 95% CI, 0.988 to 0.998; p=0.006). Conclusion Treatment-related lymphopenia was a poor prognostic factor in NPC patients.

A new recombined porcine reproductive and respiratory syndrome virus virulent strain in China

Jian-guo Dong,Lin-yang Yu,Pei-pei Wang,Le-yi Zhang,Yan-ling Liu,Peng-shuai Liang,Chang-xu Song 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.1

Porcine reproductive and respiratory syndrome (PRRS) is one of the most important swine diseases worldwide. In the present study, a new virulent strain of PRRS virus (PRRSV), GDsg, was isolated in Guangdong province, China, and caused high fever, high morbidity, and high mortality in sows and piglets. The genome of this new strain was 15,413 nucleotides (nt) long, and comparative analysis revealed that GDsg shared 82.4% to 94% identity with type 2 PRRSV strains, but only 61.5% identity with type 1 PRRSV Lelystad virus strain. Phylogenetic analysis indicated that type 2 PRRSV isolates include five subgenotypes (I, II, III, IV, and V), which are represented by NADC30, VR-2332, GM2, CH-1a, and HuN4, respectively. Moreover, GDsg belongs to a newly emerging type 2 PRRSV subgenotype III. More interestingly, the newly isolated GDsg strain has multiple discontinuous nt deletions, 131 (19 + 18 + 94) at position 1404–1540 and a 107 nt insertion in the NSP2 region. Most importantly, the GDsg strain was identified as a virus recombined between low pathogenic field strain QYYZ and vaccine strain JXA1-P80. In conclusion, a new independent subgenotype and recombinant PRRSV strain has emerged in China and could be a new threat to the swine industry of China.

Studies on the influence factors of wind dynamic responses on hyperbolic cooling tower shells

Jun-Feng Zhang,Qing-Shuai LIU,Yao-Jun Ge,Lin Zhao 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.72 No.5

Wind induced dynamic responses on hyperbolic cooling tower (HCT) shells are complicated functions of structure and wind properties, such as the fundamental frequency fmin, damping ratio ζ, wind velocity V, correlationship in meridian direction and so on, but comprehensions on the sensitivities of the dynamic responses to these four factors are still limited and disagree from each other. Following the dynamic calculation in time domain, features of dynamic effects were elaborated, focusing on the background and resonant components σB and σR, and their contributions to the total rms value σT. The σR is always less than σB when only the maximum σT along latitude is concerned and the contribution of σR to σT varies with responses and locations, but the σR couldn’t be neglected for structural design. Then, parameters of the above four factors were artificially adjusted respectively and their influences on the gust responses were illustrated. The relationships of σR and the former three factors were expressed by fitted equations which shows certain differences from the existing equations. Moreover, a new strategy for wind tunnel tests aiming at surface pressures and the following dynamic calculations, which demands less experiment equipment, was proposed according to the influence from meridian correlationship.