Dependency Distance as a Metric of Language Comprehension Difficulty

Hai Tao Liu 서울대학교 인지과학연구소 2008 Journal of Cognitive Science Vol.9 No.2

Linguistic complexity is a measure of the cognitive difficulty of human language processing. The present paper proposes dependency distance, in the framework of dependency grammar, as an insightful metric of complexity. Three hypotheses are formulated: (1) The human language parser prefers linear orders that minimize the average dependency distance of the recognized sentence (2) There is a threshold that the average dependency distance of most sentences or texts of human languages does not exceed (3) Grammar and cognition combine to keep dependency distance within the threshold. Twenty corpora from different languages with dependency syntactic annotation are used to test these hypotheses. The paper reports the average dependency distance in these corpora and analyzes the factors which influence dependency distance. The findings-that average dependency distance has a tendency to be minimized in human language and that there is a threshold of less than 3 words in average dependency distance and grammar plays an important role in constraining distance-support all three hypotheses, although some questions are still open for further research.

Reactive Synthesis of ZrB₂-based Ultra High Temperature Ceramics

Liu, Hai-Tao,Zhang, Guo-Jun The Korean Ceramic Society 2012 한국세라믹학회지 Vol.49 No.4

Reactive processing, such as reactive hot pressing (RHP) and reactive spark plasma sintering (R-SPS), is effective densification method to prepare $ZrB_2$-based ultra high temperature ceramics (UHTCs). The present paper reviewed some typical reactive processing of $ZrB_2$-based UHTCs. All the reactions from the starting materials in the reactive processing are thermodynamically favorable, which generate enough energy and driving force for the densification of the final products under a relatively low temperature. Besides, compared with non-reactive processing, anisotropic $ZrB_2$ grains, such as $ZrB_2$ platelets, can only be obtained in the reactive processing, resulting in an improvement of the mechanical properties.

Reactive Synthesis of ZrB2-based Ultra High Temperature Ceramics

Hai-Tao Liu,Guo-Jun Zhang† 한국세라믹학회 2012 한국세라믹학회지 Vol.49 No.4

Reactive processing, such as reactive hot pressing (RHP) and reactive spark plasma sintering (R-SPS), is effective densification method to prepare ZrB2-based ultra high temperature ceramics (UHTCs). The present paper reviewed some typical reactive processing of ZrB2-based UHTCs. All the reactions from the starting materials in the reactive processing are thermodynamically favorable, which generate enough energy and driving force for the densification of the final products under a relatively low temperature. Besides, compared with non-reactive processing, anisotropic ZrB2 grains, such as ZrB2 platelets, can only be obtained in the reactive processing, resulting in an improvement of the mechanical properties.

Whole Brain Radiotherapy Plus Chemotherapy in the Treatment of Brain Metastases from Lung Cancer: A Meta-analysis of 19 Randomized Controlled Trails

Liu, Wen-Jing,Zeng, Xian-Tao,Qin, Hai-Feng,Gao, Hong-Jun,Bi, Wei-Jing,Liu, Xiao-Qing Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7

Objective: To evaluate the efficacy and safety of whole brain radiotherapy (WBRT) plus chemotherapy versus WBRT alone for treating brain metastases (BM) from lung cancer by performing a meta-analysis based on randomized controlled trials (RCTs). Methods: The PubMed, Embase, CENTRAL, ASCO, ESMO, CBM, CNKI, and VIP databases were searched for relevant RCTs performed between January 2000 and March 2012. After quality assessment and data extraction, the meta-analysis was performed using the RevMan 5.1 software, with funnel plot evaluation of publication bias. Results: 19 RCTs involving 1,343 patients were included. The meta-analyses demonstrated that compared to WBRT alone, WBRT plus chemotherapy was more effective with regard to the objective response rate (OR = 2.30, 95% CI = 1.79 - 2.98; P < 0.001); however, the incidences of gastrointestinal reactions (RR = 3.82, 95% CI = 2.33 - 6.28, P <0.001), bone marrow suppression (RR = 5.49, 95% CI = 3.65 - 8.25, P < 0.001), thrombocytopenia (RR = 5.83, 95% CI = 0.39 - 86.59; P = 0.20), leukopenia (RR = 3.13, 95% CI = 1.77 - 5.51; P < 0.001), and neutropenia (RR = 2.75, 95% CI = 1.61 - 4.68; P < 0.001) in patients treated with WBRT plus chemotherapy were higher than with WBRT alone. There was no obvious publication bias detected. Conclusion: WBRT plus chemotherapy can obviously improve total efficacy rate, butalso increases the incidence of adverse reactions compared to WBRT alone. From the limitations of this study, more large-scale, high-quality RCTs are suggested for further verification.

Analysis of Key Genes and Pathways Associated with Colorectal Cancer with Microarray Technology

Liu, Yan-Jun,Zhang, Shu,Hou, Kang,Li, Yun-Tao,Liu, Zhan,Ren, Hai-Liang,Luo, Dan,Li, Shi-Hong Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

Objective: Microarray data were analyzed to explore key genes and their functions in progression of colorectal cancer (CRC). Methods: Two microarray data sets were downloaded from Gene Expression Omnibus (GEO) database and differentially expressed genes (DEGs) were identified using corresponding packages of R. Functional enrichment analysis was performed with DAVID tools to uncover their biological functions. Results: 631 and 590 DEGs were obtained from the two data sets, respectively. A total of 32 common DEGs were then screened out with the rank product method. The significantly enriched GO terms included inflammatory response, response to wounding and response to drugs. Two interleukin-related domains were revealed in the domain analysis. KEGG pathway enrichment analysis showed that the PPAR signaling pathway and the renin-angiotensin system were enriched in the DEGs. Conclusions: Our study to systemically characterize gene expression changes in CRC with microarray technology revealed changes in a range of key genes, pathways and function modules. Their utility in diagnosis and treatment now require exploration.

Size Effect on Surface Roughness in Micro Turning

Tao Zhang,Zhan-qiang Liu,Zhen-yu Shi,Chong-hai Xu 한국정밀공학회 2013 International Journal of Precision Engineering and Vol. No.

The conventional model predicts that the surface roughness decreases with feed and fits well with the measured results, even in the micro turning process. But it is observed that surface roughness increases with feed decreases when the feed is in the range of micro scale. Based on the analysis of peak-to-valley formation process, a quadratic prediction model, which divides the height of peak-tovalley into two parts: one part is piled in front of the rake face while the other is piled on the flank face and is more accurate, is established considering the effect of tool geometry, cutting parameters and pile-up of work piece. The prediction model is calibrated and verified via two groups of micro turning experiments. Results show that size effect of specific cutting energy increases the surface roughness at small feeds. The difference between the theoretical and measured results at small feeds is mainly induced by the pileup of work piece material around the rear face. The best surface roughness can be obtained when the feed per revolution equals 0.1time of the cutting edge radius.

Deformation Characteristics of Soft Soil Induced by Deep Excavation and Its Impact on Adjacent Tunnels: A Case Study in Shanghai

Tao Peng,Dongxing Ren,Chao Kang,Huanhuan Liu,Peng Xue,Hai Huang 대한토목학회 2024 KSCE Journal of Civil Engineering Vol.28 No.5

This research aims to comprehensively study the deformation characteristics of an excavation pit of 7,600 m2 (117 m long, 65 m wide and 20.8 m deep) in soft clay in Shanghai, China. The deformation characteristics of the mixing pile in both the vertical and lateral directions, ground surface movement, and surface displacement in the adjacent tunnels were comprehensively investigated. The results indicated that the maximum lateral deflection was approximately 85 mmat the end of the excavation and that the maximum lateral displacement, hm, was in the range between 0.12%He and 0.41%He. The factor of safety of the excavation was approximately 1.6, which was larger than that of most reported sites in Shanghai. The relationship between heaving and excavation depth was strong between 0.0047%He and 0.056%He, and a relatively large settlement was observed at a distance of approximately 0.2He – 0.3He. The tunnel surface of the eastbound line deformed upward and inward with a maximum horizontal convergence of 4 mm. A multilayer regression model was also validated, showing a maximum discrepancy of 26.5 mm. This research provides a valuable historical case for the documentation of the deformation characteristics of excavation pits close to existing foundation pits and tunnels.

Gingerol Inhibits Cisplatin-induced Vomiting by Down Regulating 5-Hydroxytryptamine, Dopamine and Substance P Expression in Minks

Qiu-hai Qian,Wen-hui Chen,Wang Yue,Yao-xia Wang,Zhi-hong Yang,Zhan-tao Liu 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.4

Objective: To investigate the antiemetic effect of gingerol and its multi-targets effective mechanism on 5-hydroxytryptamine (5-HT), dopamine (DA) and substance P (SP). The antiemetic effect of gingerol was investigated on a vomiting model of mink induced by cisplatin (7.5 mg· kg−1, i.p.) in 6 h observation. The levels of 5-HT, DA and distribution of substance P in the area postrema and ileum were measured by high performance liquid chromatography (HPLC) and immunohistochemistry respectively. The frequency of cisplatin induced retching and vomiting was significantly reduced by pretreatment with gingerol in a dose-dependent manner (P<0.05). Cisplatin produced a significant increase in 5-HT and DA levels in the area postrema and ileum of minks (P<0.05), and this increase was significantly inhibited by gingerol in a dose-dependent manner (P<0.05). Substance P-immunoreactive was mainly situated in the mucosa and submucosa of ileum as well as in the neurons of area postrema, and gingerol markedly suppressed the increase immunoreactivity of substance P induced by cisplatin in a dose-dependent manner (P<0.05). Gingerol has good activity against cisplatin-induced emesis in minks possibly by inhibiting central or peripheral increase of 5-HT, DA and substance P.

Research on Machining Deformation of 7050 Aluminum Alloy Aircraft Rib Forging

Yaoqiong Liu,Hai Gong,Yongbiao He,Tao Zhang,Yanjie Sun,Xiaolong Liu 한국정밀공학회 2022 International Journal of Precision Engineering and Vol.23 No.5

T-type rib strip was the key connective component between the fuselage and wing of the aircraft and the main processes for preparation of T-type rib strip consisted of forging forming, solution quenching, cold pressing and machining. The variation of residual stress and its effect on the deformation during the final machining process was quite complex. In this study, the numerical models of solution quenching, cold pressing and machining of T-type rib strip was established. The variation of residual stress on the deformation of T-type rib strip was studied. The results show that the maximum quenching stress of the T-type rib was about − 200 MPa at the surface and 150 MPa in the core. A reduction of 60% of the average residual stress can be achieved during the cold pressing process with a reduction rate of 3% and a friction coefficient of 0.3. Compared with direct machining after quenching, the deformation of machining after solution quenching and cold pressing was greatly reduced and the reduction rate reached 65.04%.

Enhancing mucosal immunity in mice by recombinant adenovirus expressing major epitopes of porcine circovirus-2 capsid protein delivered with cytosine-phosphate-guanosine oligodeoxynucleotides

Hong-tao Chang,Xiu-yuan He,Yu-Feng Liu,Lu Chen,Quan-hai Guo,Qiu-ying Yu,Jun Zhao,Xin-wei Wang,Xia Yang,Chuan-qing Wang 대한수의학회 2014 Journal of Veterinary Science Vol.15 No.3

A recombinant replication-defective adenovirus expressingthe major epitopes of porcine circovirus-2 (PCV-2) capsidprotein (rAd/Cap/518) was previously constructed and shownto induce mucosal immunity in mice following intranasaldelivery. In the present study, immune responses induced byintranasal immunization with a combination of rAd/Cap/518and cytosine-phosphate-guanosine oligodeoxynucleotides(CpG ODN) were evaluated in mice. The levels ofPCV-2-specific IgG in serum and IgA in saliva, lung, andintestinal fluids were significantly higher in the groupimmunized with rAd/Cap/518 and CpG ODN than animalsimmunized with rAd/Cap/518 alone. The frequencies ofIL-2-secreting CD4+ T cells and IFN-γ-producing CD8+ T cellswere significantly higher in the combined immunizationgroup than mice immunized with rAd/Cap/518 alone. Thefrequencies of CD3+, CD3+CD4+CD8−, and CD3+CD4−CD8+T cells in the combined immunization group were similar tothat treated with CpG ODN alone, but significantly higherthan mice that did not receive CpG ODN. PCV-2 load afterchallenge in the combined immunization group wassignificantly lower than that in the phosphate-buffered salineplacebo group and approximately 7-fold lower in the grouptreated with CpG ODN alone. These results indicate thatrAd/Cap/518 combined with CpG ODN can enhance systemicand local mucosal immunity in mice, and represent apromising synergetic mucosal vaccine against PCV-2.