http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
A Case of High-degree Atrioventricular Block in a Patient with Ankylosing Spondylitis
( Sang Rok Lee ),( Hyung Wook Park ),( Sang Yub Lim ),( Seo Na Hong ),( Kye Hun Kim ),( Il Suk Sohn ),( Young Joon Hong ),( Ju Han Kim ),( Weon Kim ),( Young Keun Ahn ),( Myung Ho Jeong ),( Jeong Gwan 대한내과학회 2005 대한내과학회 추계학술대회 Vol.69 No.10
Fault Current Limiting Characteristics of Flux-lock Type SFCL with Several Secondary Windings
Lim, Sung-Hun,Park, Chung-Ryul,Han, Byoung-Sung,Park, Hyoung-Min,Cho, Yong-Sun,Choi, Hyo-Sang The Korean Institute of Electrical and Electronic 2005 Transactions on Electrical and Electronic Material Vol.6 No.5
We investigated fault current limiting characteristics of the flux-lock type superconducting fault current limiter (SFCL), which consisted of a primary winding and several secondary windings connected in series between $high-T_C$ superconducting (HTSC) thin films. Each YBCO thin film has a 2 mm wide and 42 cm long meander line with 14 stripes of different length. The power imbalance due to the slight difference of Ie between YBCO current limiting elements causes the significant power burden on YBCO element with lower $I_C$. We confirmed from our experiments that the mutual coupling between the primary winding and secondary windings of the flux-lock type SFCL reduced the power imbalance between YBCO current limiting elements compared with the resistive type SFCL connected in series.
Lim, Tae-Gyu,Kim, Jong-Eun,Lee, Sung-Young,Park, Jun Seong,Yeom, Myung Hun,Chen, Hanyong,Bode, Ann M.,Dong, Zigang,Lee, Ki Won MDPI 2014 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.15 No.11
<P>Soy isoflavone is an attractive source of functional cosmetic materials with anti-wrinkle, whitening and skin hydration effects. After consumption, the majority of soy isoflavones are converted to their metabolites in the human gastrointestinal tract. To understand the physiological impact of soy isoflavone on the human body, it is necessary to evaluate and address the biological function of its metabolites. In this study, we investigated the effect of 6,7,4'-trihydroxyisoflavone (6,7,4'-THIF), a major metabolite of daidzein, against solar UV (sUV)-induced matrix metalloproteinases (MMPs) in normal human dermal fibroblasts. MMPs play a critical role in the degradation of collagen in skin, thereby accelerating the aging process of skin. The mitogen-activated protein/extracellular signal-regulated kinase (MEK)/extracellular signal-regulated kinase (ERK), mitogen-activated protein kinase (MKK)3/6/p38 and MKK4/c-Jun <I>N</I>-terminal kinases (JNK) signaling pathways are known to modulate MMP-1 function, and their activation by sUV was significantly reduced by 6,7,4'-THIF pretreatment. Our results also indicated that the enzyme activity of protein kinase C (PKC)α, an upstream regulator of MKKs signaling, is suppressed by 6,7,4'-THIF using the<I> in vitro</I> kinase assay. Furthermore, the direct interaction between 6,7,4'-THIF and endogenous PKCα was confirmed using the pull-down assay. Not only sUV-induced MMP-1 expression, but also sUV-induced signaling pathway activation were decreased in PKCα knockdown cells. Overall, we elucidated the inhibitory effect of 6,7,4'-THIF on sUV-induced MMPs and suggest PKCα as its direct molecular target.</P>
Thrombospondins Mediate the Adhesion of Osteoblast to Extracelluar Matrix
Lim, Dong-Jin,Bae, In-Ho,Jeong, Byung-Chul,Kim, Sun-Hun,Park, Bae-Keun,Kang, Un-Chul,Lee, Shee-Eun,Song, Sang-Hun,Koh, Jeong-Tae KOREAN ACADAMY OF ORAL BIOLOGY 2008 International Journal of Oral Biology Vol.33 No.3
Thrombospondins (TSP-l, TSP-2) are secretory extracellular glycoproteins that are involved in a variety of physiological processes such as tumor cell adhesion, invasion, and metastasis. The present study was undertaken to elucidate the involvement of thrombospondins in the adhesion of osteoblast-like cells using the TSP-l or TSP-2 antisense MG63 and MC3T3-El cell lines. For downregulation of TSPs expression, we prepared antisense constructs for TSP-l and TSP-2 using the pREP4 an episomal mammalian expression vector, which be able to produce the specific antisense oligonucleotides around chromosome. MG63 and MC3T3-El osteoblast-like cells were transfected with the antisense constructs and nonliposomal Fugene 6, and then selected under hygromycin B (50 μg/ml) treatment for 2 weeks. Western blot analysis revealed that expression of the TSP proteins was downregulated in the antisense cell lines. The cell adhesion assay showed that adhesive properties of TSP-l and TSP-2 antisense MG63 cells on the polystyrene culture plate were reduced to 17% and 21% of the control cells, respectively, and those of the TSP-l and TSP-2 antisense MC3T3-El cells also decreased to 19% and 27% of control, respectively. Adhesion of TSP-l and TSP-2 antisense MC3T3-El cells on Type I collagen-coated culture plate decreased to 27% and 76%, respectively. These results indicate that TSP-l and TSP-2 proteins may have an important role in adhesion of osteoblast-like cells to extracellular matrix.
Bridge Type Fault Current Limiter using Switching Operation of HTSC Thin Film
Sung-Hun Lim,Hyo-Sang Choi,Byoung-Sung Han 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.45 No.3
In this paper, we propose a bridge type fault current limiter (FCL) using switching operation of high-TC superconducting (HTSC) thin lm. The proposed bridge type FCL consists of HTSC thin lm, a diode bridge and a dc reactor. A controller for the operation of an interrupter is required in the conventional bridge type FCL to prevent the continuous increase of fault current after a fault happens. On the other hand, the proposed bridge type FCL can limit the fault current without the interrupter and the controller for its operation by the resistance generated when the gradually increasing fault current exceeds the HTSC thin lm's critical current. We calculated the time when the gradually increasing fault current would be limited by the resistance generated in the HTSC thin lm after a fault happened and conrmed that it could be dependent on the amplitude of the source voltage. The experimental results agreed well with the calculated ones from simulation.
Comparative Study of Current Limiting Characteristics for Hybrid Type and Flux-Lock Type SFCLs
Sung-Hun Lim 한국전기전자재료학회 2007 Transactions on Electrical and Electronic Material Vol.8 No.5
In this paper, we compared the current limiting characteristics of both the hybrid type and the flux-lock type superconducting fault current limiters (SFCLs), which have a magnetic coupling structure between a primary winding and several secondary windings. The limiting impedances of two SFCLs were derived from each equivalent circuit considering the design parameters of SFCL such as the self-inductance of secondary winding and the resistance of high-TC superconducting (HTSC) element. Through the comparison for the limiting impedances of two SFCLs considering the dependence of the HTSC element’s resistance on the applying voltage into the SFCL, the hybrid type SFCL was confirmed to have larger limiting impedance with smaller resistance of HTSC element than the flux-lock type SFCL. It was expected from the analysis that the hybrid type SFCL was more advantageous than the flux-lock type SFCL from the viewpoint of the fault current limiting level.