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      • Late Holocene glacial advance and ice shelf growth in Barilari Bay, Graham Land, west Antarctic Peninsula

        Christ, Andrew J.,Talaia-Murray, Manique,Elking, Natalie,Domack, Eugene W.,Leventer, Amy,Lavoie, Caroline,Brachfeld, Stefanie,Yoo, Kyu-Cheul,Gilbert, Robert,Jeong, Sun-Mi,Petrushak, Stephen,Wellner, J Geological Society of America 2015 Geological Society of America bulletin Vol.127 No.1

        <P>Three marine sediment cores were collected along the length of the fjord axis of Barilari Bay, Graham Land, west Antarctic Peninsula (65°55′S, 64°43′W). Multi-proxy analytical results constrained by high-resolution geochronological methods (<SUP>210</SUP>Pb, radiocarbon, <SUP>137</SUP>Cs) in concert with historical observations capture a record of Holocene paleoenvironmental variability. Our results suggest early and middle Holocene (>7022–2815 cal. [calibrated] yr B.P.) retreated glacial positions and seasonally open marine conditions with increased primary productivity. Climatic cooling increased sea ice coverage and decreased primary productivity during the Neoglacial (2815 to cal. 730 cal. yr B.P.). This climatic cooling culminated with glacial advance to maximum Holocene positions and expansion of a fjord-wide ice shelf during the Little Ice Age (LIA) (ca. 730–82 cal. yr B.P.). Seasonally open marine conditions were achieved and remnant ice shelves decayed within the context of recent rapid regional warming (82 cal. yr B.P. to present). Our findings agree with previously observed late Holocene cooling and glacial advance across the Antarctic Peninsula, suggesting that the LIA was a regionally significant event with few disparities in timing and magnitude. Comparison of the LIA Antarctic Peninsula record to the rest of the Southern Hemisphere demonstrates close synchronicity in the southeast Pacific and southern most Atlantic region but less coherence for the southwest Pacific and Indian Oceans. Comparisons with the Northern Hemisphere demonstrate that the LIA Antarctic Peninsula record was contemporaneous with pre-LIA cooling and sea ice expansion in the North Atlantic–Arctic, suggesting a global reach for these events.</P>

      • KCI등재후보

        Visual Evoked Potentials in Guillain-Barré Syndrome

        Levent Güngör,,İnci Güngör,Hilal Eser Öztürk,Musa Kazım Onar 대한신경과학회 2011 Journal of Clinical Neurology Vol.7 No.1

        Background and Purpose:Guillain-Barré syndrome (GBS) is an acute demyelinating polyneuropathy with various clinical features. Optic neuritis occurs in rare cases. In this study we determined the incidence and patterns of visual evoked potential (VEP) abnormality in GBS in association with ophthalmologic findings. Methods:Thirty-two patients with a diagnosis of GBS were included in the study. The correlation between pathologic VEPs and categories of neurologic deficit and electrophysiological findings were examined statistically. Results:The patients ranged in age from 19 to 77 years. Five cases (16%) had abnormal VEPs. All five of these patients exhibited increased P100 latency differences between the two eyes. Other abnormalities were prolonged p100 latency, increased interocular amplitude difference, and distorted p100 configuration. Pathologic signs on ophthalmologic examination were observed in 80% of patients with abnormal VEPs. VEP abnormality was never present in pure axonal forms. There was no significant correlation between pathologic VEP and cerebrospinal fluid protein level or categories of neurologic deficits. Conclusions:Involvement of the optic pathways is not a frequent finding in GBS. When present it is always asymmetric and generally accompanied with pathologic findings on ophthalmologic examination. VEPs may be abnormal in different clinical variants of GBS, and especially in demyelinating forms.

      • KCI등재
      • KCI등재

        Efficiency of MVP ECG Risk Score for Prediction of Long-Term Atrial Fibrillation in Patients With ICD for Heart Failure With Reduced Ejection Fraction

        Levent Pay,Ahmet Çağdaş Yumurtaş,Ozan Tezen,Tuğba Çetin,Semih Eren,Göksel Çinier,Mert İlker Hayıroğlu,Ahmet İlker Tekkeşin 대한심장학회 2023 Korean Circulation Journal Vol.53 No.9

        Background and Objectives: The morphology-voltage-P-wave duration (MVP) electrocardiography (ECG) risk score is a newly defined scoring system that has recently been used for atrial fibrillation (AF) prediction. The aim of this study was to evaluate the ability of the MVP ECG risk score to predict AF in patients with an implantable cardioverter defibrillator (ICD) and heart failure with reduced ejection fraction in long-term follow-up. Methods: The study used a single-center, and retrospective design. The study included 328 patients who underwent ICD implantation in our hospital between January 2010 and April 2021, diagnosed with heart failure. The patients were divided into low, intermediate and high-risk categories according to the MVP ECG risk scores. The long-term development of atrial fibrillation was compared among these 3 groups. Results: The low-risk group included 191 patients, the intermediate-risk group 114 patients, and the high-risk group 23 patients. The long-term AF development rate was 12.0% in the low-risk group, 21.9% in the intermediate risk group, and 78.3% in the high-risk group. Patients in the high-risk group were found to have 5.2 times higher rates of long-term AF occurrence compared to low-risk group. Conclusions: The MVP ECG risk score, which is an inexpensive, simple and easily accessible tool, was found to be a significant predictor of the development of AF in the long-term follow-up of patients with an ICD with heart failure with reduced ejection fraction. This risk score may be used to identify patients who require close follow-up for development and management of AF.

      • KCI등재
      • KCI등재

        Estimation of the Compressive Strength of Concrete under Point Load and its Approach to Strength Criterions

        Levent Selçuk,H. Süleyman Gökçe 대한토목학회 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.6

        The point load strength (Is(50)) is an alternative mechanical parameter to predict the compressive strength of concrete. The scope of this investigation is to develop an empirical equation relating the point load strength and compressive strength of concrete. In this context, crushed limestone aggregates at two different strength levels were used in concrete mixture. Point load strength and compressive strength tests on concrete specimens which had 6 different compressive strengths were performed for each limestone aggregate. A series of regression analyses was applied using any general statistical package to evaluate the ratio of point load strength test to cube compressive strength of concrete, (Is(50)/fcu). The accuracy and reliability of the equation in this investigation was assessed by means of the Mean Absolute Percent Error (MAPE). The relative error can be considered reasonably well for the empirical relationship. The ratio of Is(50)/fcu was also verified by a large database collected from previous studies. The proposed equation is quite compatible with the database. Furthermore, the ratio of Is(50)/fcu indicates significant material property of concrete and defines the material constant in strength criterions. It can be used to estimate the axial compressive strength of concrete under confining stress without performing triaxial tests, considered Hoek-Brown and Johnson empirical failure criterions.

      • KCI등재

        Is SYNTAX Score Predictive of Atrial Fibrillation after On-Pump Coronary Artery Bypass Graft Surgery?

        Levent Cerit,Hamza Duygu,Kamil Gulsen,Hatice S Kemal,Barcın Ozcem,Ozlem Balcioglu,Aziz Gunsel,Ozgur Tosun,Volkan Emren 대한심장학회 2016 Korean Circulation Journal Vol.46 No.6

        Background and Objectives: The relationship of synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) score and development of atrial fibrillation (AF) after coronary artery bypass surgery (CABG) has not been studied. Therefore, we assessed the relationship between the SYNTAX score and development of AF after CABG (POAF). Subjects and Methods: The medical records of consecutive patients, who underwent CABG surgery from January 2013 to September 2015, were retrospectively reviewed for the development of AF in the postoperative period. SYNTAX score, clinical and echocardiographic parameters were evaluated. The independent variables for the development of POAF were defined and their predictive values were measured. Results: The study group consisted of 106 patients, of which 36 (34%) developed POAF. Age, hypertension, stroke, chronic obstructive pulmonary disease (COPD), heart failure (HF), diabetes mellitus (DM), left atrial diameter, neutrophil/lymphocyte ratio, platelet large cell ratio, creatinine, blood urea nitrogen and SYNTAX score were identified as important variables for the development of POAF. However, in logistic regression analysis COPD (OR=19.313, 95% CI=2.416-154.407, p=0.005), HF (OR=28.362, 95% CI=2.034-395.515, p=0.013), SYNTAX score (OR=0.863, 95% CI=0.757-0.983, p=0.026), and DM (OR=20.770, 95% CI=3.791-113.799, p<0.001) appeared as independent variables predicting the development of POAF. In receiver operation characteristic analysis, SYNTAX score (≥22.25) (AUC=0.777, 95% CI=0.676-0.877, p<0.001) was one of the strongest predictors for the development of POAF. Conclusion: The SYNTAX score level was independently associated with the development of AF after CABG.

      • KCI등재후보

        Mytilus Galloprovincialis and Metal Contaminants: Health Risk Assessment from Sinop Coasts

        Levent BAT,Ayş,ah Ö,ZTEKIN,Elif ARICI,Fatih Ş,AHIN 한국식품보건융합학회 2021 식품보건융합연구 (KJFHC) Vol.7 No.4

        The goal of this study was to quantify the content of heavy metals (Zn, Cu, Cd, Pb, Hg) in the bivalve Mytilus galloprovincialis, which was obtained from the Black Sea s Sinop peninsula, as well as estimate the health risks. Concentrations of heavy metals in mussels’ soft tissues ranged between 16.4-21.8, 0.52-0.93, 0.13-0.45; 0.015-0.019 and 0.006-0.011mg kg-1 wet weight for Zn, Cu, Pb, Hg and Cd, respectively. In general, metal concentrations in mussels were quite low. In mussels, Zn was the most prevalent element, followed by Cu. Regarding the monthly variation, although relatively higher tissue metal concentrations were observed in August compared to July, no statistical difference was found. The estimated daily intakes did not exceed the tolerable intakes. There was no health risk since the total hazard index was far below critical value 1. This demonstrates that eating mussels from the Sinop coasts in 2019 does not cause any health risks in infants, children, or adult. Mussels have a risk index of less than 10-6, which is considered insignificant. In conclusion, the results of this study show that there is no heavy metal pollution in the mussels collected from Sinop coasts.

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