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환경 및 시간경과에 따른 건축용 단열재의 열전도율 변화에 관한 실험적 연구
이승언,강재식,정영선,최현중 대한건축학회 2003 대한건축학회논문집 Vol.19 No.12
The objective of this research is to provide the basic experimental data for thermal insulation design standard of buildings and for test criterion. We tested the thermal conductivity of insulation materials which was the insulation materials in domestic buildings with environmental condition change and long-time elapse. In research, we measured change of thermal conductivity with change of contained water rate by weight, test temperature change and the passage of time. the specimens of insulation materials were kept in test condition, which was influenced by the outside environment during long-time elapse test. The result of the research shows 1)the contained water rate of artificial mineral fiber insulations is higher than others, 2)thermal conductivity rises as test temperature goes up, 3)the thermal conductivity of the extruding insulations and hardened Urethane foam changes with environmental condition and time elapse. As a result, the test methods and standards for thermal conductivity properties have much room for consideration.
구내 표준 방사선사진을 이용한 구내방사선촬영기의 선질 평가
이상섭,권혁락,심우현,오승현,이지연,전국진,김기덕,박창서 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.3
Purpose : This study was to evaluate the beam quality of intraoral X-ray equipments used at Yonsei University Dental Hospital (YUDH) using the half value layer (HVL) and the characteristic curve of intraoral standard X-ray film. Materials and Methods : The study was done using the intraoral X-ray equipments used at each clinical department at YUDH. Aluminum filter was used to determine the HVL. Intraoral standard film was used to get the characteristic curve of each intraoral X-ray equipment. Results : Most of the HVLs of intraoral X-ray equipments were higher than the least recommended thickness, but the REX 601 model used at the operative dentistry department and the X-707 model used at the pediatric dentistry department had HVLs lower than the recommended thickness. The slopes of the characteristic curves of films taken using the PANPAS 601 model and REX 601 model at operative dentistry department, the X-705 model of prosthodontic dentistry department, and the REX601 model at the student clinic were relatively low. Conclusion : HVL and the characteristic curve of X-ray film can be used to evaluate the beam quality of intraoral X-ray equipment. In order to get the best X-ray films with the least radiation exposure to patients and best diagnostic information in clinical dentistry, X-ray equipment should be managed in the planned and organized fashion. (Korean J Oral Maxillofac Radiol 2000; 30: 183-188)
건축 단열재의 장기 경년변화에 따른 열전도율 변화에 관한 실험 연구 Ⅱ
최현중,정영선,김경우,강재식,이승언 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1
The objective of this study is to test for thermal conductivity of architecture insulation materials in domestic buildings with environmental condition change. In study, we measured change of thermal conductivity with test temperature change, long-time leaving and change of contained water rate. For long-time leaving test, the specimens of building insulation materials were kept in test conditions, which were influenced by the outside environment. The results of the study show 1) the contained water rate of artificial mineral fiber insulations was big for others, 2) thermal conductivity rose as test temperature(median) grew up and 3) the extruding insulations and hardened Urethane foam changed thermal conductivity with environmental condition and time elapse.
Pt-Catalyzed Growth of Amorphous SiOx Nanowires
Hyoun Woo Kim,Ik-Mo Lee,Jae-Won Soh,Jong Woo Lee,Keun Hyeung Lee,Mi Kyoung Park,Sang-Eon Park,Seung Hyun Shim,Wan In Lee 한국물리학회 2007 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.50 No.I
We have fabricated SiO$_x$ nanowires on a large scale through a Pt-catalyzed process. The scanning electron microscopy (SEM) investigation revealed that the nanowires had diameters in the range of 30 $\sim$ 130 nm. X-ray diffraction (XRD), selected area electron diffraction (SAED), and energy-dispersive X-ray (EDX) analyses indicated that the nanowires were amorphous and consisted only of Si and O elements. The growth of the SiO$_x$ nanowires was most likely controlled by the base-growth mechanism with the assistance of the underlying Pt layer. The room-temperature PL spectrum measurement showed a broad emission band, peaking around 3.0 eV. This simple heating method, with the effectiveness of the Pt catalyst, can be applied to a wide range of substrate materials, which may contribute to producing various useful nanostructures.
Minimal heating dose: a novel biological unit to measure infrared irradiation
Lee, Hyoun Seung,Lee, Dong Hun,Cho, Soyun,Chung, Jin Ho Blackwell Publishing Ltd 2006 Photodermatology, photoimmunology & photomedicine Vol.22 No.3
<P>Background and Objective</P><P>Infrared (IR) rays, which comprise approximately 40% of the solar radiation which reaches the earth's surface, have received relatively scant attention. As no standard method has yet been agreed upon for the biological evaluation of IR irradiation, the objective of this study is to suggest a new unit for IR irradiation.</P><P>Methods</P><P>The skin temperature of 38 Korean volunteers was measured after IR irradiation with varying irradiance.</P><P>Results</P><P>Skin temperature after IR irradiation at an irradiance of 2.02 W/cm<SUP>2</SUP> remained unchanged after 652±22 s (mean±standard error), which corresponds, in this case, to a total radiation dose of IR 1317.3±44.84 J/cm<SUP>2</SUP>. This quantity was designated as the minimal heating dose (MHD). We also demonstrated that MHD increased with increasing IR irradiance at lower IR irradiance (1.17 and 2.02 W/cm<SUP>2</SUP>), whereas it became constant at higher irradiance (2.87 and 3.22 W/cm<SUP>2</SUP>). No statistically significant correlations were detected between MHD and volunteers' ages, erythema index, or melanin index.</P><P>Conclusion</P><P>We propose ‘MHD’ as a biological unit for the measurement of IR irradiation.</P>
Lee, Hyoun Wook,Lee, Eun Hee,Ha, Seung Yeon,Lee, Chang Hun,Chang, Hee Kyung,Chang, Sunhee,Kwon, Kun Young,Hwang, Il Seon,Roh, Mee Sook,Seo, Jeong Wook Blackwell Publishing Asia 2012 Pathology international Vol.62 No.9
<P>MicroRNA (miRNA) has a critical effect on tumorigenesis through post‐transcriptional modification and is considered to be potential biomarkers for cancer diagnosis and treatment monitoring. We evaluated the expression pattern of three selected miRNAs (miR‐21, miR‐155, and let‐7a) to evaluate their potential roles by quantitative reverse transcription‐polymerase chain reaction using formalin‐fixed and paraffin‐embedded tissues of 63 surgically resected pulmonary neuroendocrine (NE) tumors (19 typical carcinoids (TCs), 6 atypical carcinoids (ACs), 19 large cell NE carcinomas (LCNECs), and 19 small cell lung carcinomas (SCLCs). Control amplification for U6 small nuclear RNA (U6) was performed in all samples. Normalized Ct values were calculated (Ct<SUB>Experimental miRNA</SUB>‐Ct<SUB>U6</SUB>) for each case and recorded. The expression levels of miR‐21 and miR‐155 were significantly higher in high‐grade NE carcinomas (LCNECs and SCLCs) than in carcinoid tumors (TCs and ACs) (each <I>P</I> < 0.001). The expression level of miR‐21 in carcinoid tumors with lymph node metastasis was significantly higher than in carcinoid tumors without lymph node metastasis (<I>P</I>= 0.010). To the best of our knowledge, the present study is the first to examine the expression patterns of miR‐21 and miR‐155 as an adjunctive diagnostic tool or clinically relevant biomarkers for pulmonary NE tumors.</P>
Development of the Bovine Corneal Opacity Test in Korea
( Hyoun Kyoung Lee ),( Kyoung Jin Noh ),( Seung Hyeok Seok ),( Min Won Baek ),( Hui Young Lee ),( Dong Jae Kim ),( Yi Rang Na ),( Sung Hoon Park ),( Dutta Noton Kumar ),( Byoung Hee Lee ),( Bae Hwan K 한국동물실험대체법학회 2007 한국동물실험대체법학회 학술대회집 Vol.2007 No.1
The Bovine Corneal Opacity and Permeability (BCOP) assay have been proposed as reliable alternatives to the Draize test. Wider use of the method requires extensive international harmonization study for the validation of the BCOP assay as alternatives. The aim of this work is to establish the BCOP assay in Korea for the international harmonization. In this study, six chemicals and three cosmetics were selected for the test. The eye irritation of the chemicals has already evaluated by the ECVAM(European Centre for the Validation of Alternative Methods). We evaluate the eye irritation of them by the only bovine corneal opacity in the BCOP assay. The Draize test was also preformed for comparative purpose in three chemicals and three cosmetics. For opacity alone, values obtained for three chemicals showed a correlation of r=0.994 (p=0.001) with our Draize score. A correlation coefficient between our Draize score and the ECVAM`s Draize score was 0.982 (p=0.003). The bovine corneal opacity values of additional three chemicals showed a correlation of r=0.968 (p<0.001) with ECVAM`s Draize score. All of three cosmetics were evaluated as non-irritants by the bovine corneal opacity values and our Draize score. These results indicate the international harmonization of the BCOP assay is possible. In further study, the international harmonization study has to be organized with more chemicals and products in more countries.
Establishment of the Neutral Red Uptake Assay as Alternatives to the Draize test and its Validation
( Hyoun Kyoung Lee ),( Kyoung Jin Noh ),( Seung Hyeok Seok ),( Min Won Baek ),( Hui Young Lee ),( Dong Jae Kim ),( Yi Rang Na ),( Sung Hoon Park ),( Dutta Noton Kumar ),( Byoung Hee Lee ),( Bae Hwan K 한국동물실험대체법학회 2007 한국동물실험대체법학회 학술대회집 Vol.2007 No.1
The necessity of using animals to test whether new chemicals and products are eye irritants has been questioned over the last 20 years. During this process, numerous non-animal methods have been proposed as reliable alternatives to the Draize test. The neutral red uptake assay is the in vitro method to test the eye irritation of chemicals and products. We need to validate the neutral red uptake assay as alternatives for the international harmonization. Therefore, we studied for the establishment of the neutral red uptake assay in Korea. In this study, we evaluated the eye irritation of five chemicals and three cosmetics by the Draize test and the neutral red uptake assay. The results of the neutral red uptake assay showed a correlation of r=−0.893(p=0.107) with our Draize score in two chemicals. And the results of the neutral red uptake assay showed correlation of r=0.892(p=0.017) with the Draize score obtained from the ECVAM (European Centre for the Validation of Alternative Methods) in additional three chemicals. All of three cosmetics were evaluated as non-irritants by our Draize test and the neutral red uptake assay. As a result, the neutral red uptake assay was established in Korea. For the international harmonization, the validation study has to be performed with more chemicals and products in more countries.