국화와 칼, 술, 그리고 시

秦惠蘭(Qin Hui Lan) 한국동서비교문학학회 2002 동서 비교문학저널 Vol.0 No.7

Multicolour carbon dots with excitation‑independent emission by microwave solvothermal reaction

Xiao‑Lan Wei,Qin‑Ling Shi,Lan Jiang,Yu Qin 한국탄소학회 2023 Carbon Letters Vol.33 No.1

Carbon dots (CDs) with tunable fluorescence emissions have been developed from a wide range of small organic molecules with various bottom-up syntheses. However, most of them were prepared under high temperatures and high pressures with long reaction times and tedious purification processes. In addition, previously reported carbon dots frequently displayed excitation-dependent emissions, which restrict their further applications. Herein, we present a simple and rapid microwaveassisted solvothermal synthesis of multicolour carbon dots with excitation-independent emissions. In ethylene glycol, the green (G)-CDs emitting at 537 nm with a quantum efficiency (QY) of 15% were obtained by using a single precursor of phloroglucinol, and blue (B)- and yellow (Y)-CDs emitting at 436 nm and 557 nm with QYs of 55% and 28% were derived with additives of o- and m-phenylenediamine, respectively. Analyses of their chemical structures and optical processes suggest that highly polymeric carbon dots were uniformly formed from the small molecules and their fluorescences were predominantly originated from rapid direct recombination. Furthermore, emissions at different wavelengths were mainly attributed to different degrees of oxidation (13.9%, 15.2% and 16.4% oxygen in B-, G- and Y-CDs, respectively) and different proportions of pyrrolic nitrogen (10.4% and 1.40% in B- and Y-CDs, respectively). To demonstrate the application feasibility, the obtained carbon dots were utilized for ion detection and anti-counterfeiting. Based on static quenching of the carbon dots’ fluorescence, micro amounts of ferric ion in water samples were detected selectively and reproducibly. Moreover, the anti-counterfeiting pattern constructed by the carbon dots emitted fluorescence under ultraviolet illumination, but concealed perfectly under daylight. This achievement is of great potential for developing multicolour carbon dots of high qualities.

중국 유학생의 한국 대학생활 적응 예측모형

림금란(Lin Qin Lan),김희경(Kim, Hee Kyung) 한국간호교육학회 2011 한국간호교육학회지 Vol.17 No.3

Purpose: On the basis of the theoretical framework of a combination of Roy’s adaptation theory and Lazarus & Folkman’s theory of stress - appraise coping, the purpose of this study was to predict effect factors of adaptation to university life of Chinese international students in Korea. After this, a model of adaptation to university life of Chinese international students in Korea was constructed. Methods: A questionnaire was used to survey 369 Chinese international students from one university in Korea, which was analyzed by using PASW Statistics 18.0 and LISREL 8.7. Results: This theoretical model explained adaptation to university life of Chinese international students at 75.0% in Korea. Physical symptoms, loneliness, acculturation stress and self-efficacy directly affected the adaptation to university life. Korean language proficiency indirectly affected adaptation to university life through self-efficacy. Conclusion: Results of this study provided theoretical basis for the future health care of university- centered health centers. For improving adaptation to university life of Chinese international students in Korea, education and nursing measures for reducing physical symptoms, loneliness and acculturation stress, and improving Korean language proficiency and self-efficacy are proposed for further research and development.

Reports ; Adrenergic receptor β2 activation by stress promotes breast cancer progression through macrophages M2 polarization in tumor microenvironment

( Jun-fang Qin ),( Feng-jiao Jin ),( Ning Li ),( Hai-tao Guan ),( Lan Lan ),( Hong Ni ),( Yue Wang ) 생화학분자생물학회 2015 BMB Reports Vol.48 No.5

Stress and its related hormones epinephrine (E) and norepinephrine (NE) play a crucial role in tumor progression. Macrophages in the tumor microenvironment (TME) polarized to M2 is also a vital pathway for tumor deterioration. Here, we explore the underlying role of macrophages in the effect of stress and E promoting breast cancer growth. It was found that the weight and volume of tumor in tumor bearing mice were increased, and dramatically accompanied with the rising E level after chronic stress using social isolation. What is most noteworthy, the number of M2 macrophages inside tumor was up-regulated with it. The effects of E treatment appear to be directly related to the change of M2 phenotype is reproduced in vitro. Moreover, E receptor ADRβ2 involved in E promoting M2 polarization was comprehended simultaneously. Our results imply psychological stress is influential on specific immune system, more essential for the comprehensive treatment against tumors. [BMB Reports 2015; 48(5): 295-300]

Effects of Gastric Cancer Cells on the Differentiation of Treg Cells

Hu, Jing-Lan,Yang, Zhen,Tang, Jian-Rong,Fu, Xue-Qin,Yao, Lan-Jie Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8

The aim of this study was evaluated the prevalence of Treg cells in peripheral blood in patients with gastric cancer, and investigate the effect of gastric cancer cells on their differentiation. ELISA was employed to assess the concentrations of TGF-${\beta}$ and IL-10 in gastric cancer patients' serum. Then, mouse gastric cancer cells were co-cultured with T lymphocytes or T lymphocytes + anti-TGF-${\beta}$. Flow cytometric analysis and RT-PCR were then performed to detect Treg cells and TGF-${\beta}$ and IL-10 expression in gastric cancer cells. Our data showed that the expression of TGF-${\beta}$ and IL-10 in the patients with gastric cancer was increased compared to the case with healthy donors. The population of Treg cells and the expression levels of TGF-${\beta}$ and IL-10 in the co-culture group were much higher than in the control group (18.6% vs 9.5%) (P<0.05). Moreover, the population of Treg cells and the expression levels of TGF-${\beta}$ and IL-10 in the co-culture systerm were clearly decreased after addition of anti-TGF-${\beta}$ (7.7% vs 19.6%) (P<0.01). In conclusion, gastric cancer cells may induce Treg cell differentiation through TGF-${\beta}$, and further promote immunosuppression.

Degradation Model and Evaluation Criteria for the Seismic Behavior of Corrosion H-section Steel Column

Guang-chong Qin,Tao Lan,Qing Qin,Shan-hua Xu,Zong-xing Zhang 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.8

The cross section would be reduced and the material properties of the steel structure would be deteriorated under the corrosion environment, which will have different effects on the earthquake resistant behavior. This paper takes corroded H-steel column as the research object. Firstly, the influence on the failure mode, bearing capacity, hysteretic properties, ductility and hysteretic energy is analyzed from specific factors which consist of different width-to-thickness on flange, different height-to-thickness on web and different axial compression ratios by FEA. The results show that, the area of the hysteresis loop diminishes gradually, the bearing capacity decrease clearly, the accumulative energy dissipation and ductility coefficient decreased continuously, and the degradation laws of buckling load, peak load, hysteretic energy and ductility coefficient of corroded H-steel columns are thereby established. When the thickness of flange decreased by 30%, the peak load decreased by 32% and hysteretic energy decreased by 77%. However, the peak load decreased by 14% and hysteretic energy decreased by 40% when the thickness of web decreased by 30%. When the axial compression ratio is 0.6, and the mass loss ratio of corroded H-steel columns reached 22%, the peak load and hysteretic energy decreased by 28% and 51% respectively. Secondly, the hysteretic model of load-displacement of corroded H-steel members under cyclic loading is proposed based on the simulation results and the degradation model of characteristic point of skeleton line was given. Finally, the evaluation criteria are proposed based on the seismic performance objectives, and the classification of failure types as well as the overall performance evaluation of corroded steel members are carried out.

중국 관상동맥질환자의 심장재활지식, 교육요구도 및 자가간호행위

림금란(Lin Qin Lan),김희경(Kim, Hee Kyung),이현주(Lee, Hyun Ju) 한국간호교육학회 2009 한국간호교육학회지 Vol.15 No.2

여성독거노인의 우울과 삶의 질과의 관계

림금란(Lin Qin Lan),김희경(Kim, Hee Kyung),안정선(Ann, Jung Sun) 한국노년학회 2011 한국노년학 Vol.31 No.1

본 연구의 목적은 여성독거노인의 우울과 삶의 질과의 관계에서 사회적 지지와 사회적 활동의 역할 즉 조절효과와 매개효과를 검정하여 그들의 우울을 줄이고 삶의 질을 높이기 위한 기초자료를 제공하는데 있다. 서술적 조사연구로써 K시의 여성독거노인 129명을 대상으로 2010년 6월부터 7월 까지 설문지를 이용하여 자료수집하고, SPSS Win 18.0 program으로 통계처리 하였다. 연구결과 여성독거노인의 평균 연령은 77.5세, 평균 독거기간은 14년이었다. 여성독거노인의 우울은 2.65점(±.42)으로 보통이상의 우울을 경험하고, 삶의 질은 2.80점(±.57), 사회적 지지는 3.34점(±.57)으로 보통정도의 삶을 영위하며 중간정도의 사회적 지지를 받는다고 생각하였다. 사회적 활동 중 여가활동은 3.75점(±1.08), 봉사활동은 3.80점(±.00)으로, 여가활동 시 보통이상의 만족도를 가지며, 경제활동은 2.84점(±1.00)으로 경제활동 시 보통정도의 만족도를 가지는 것으로 나타났다. 여성독거노인의 우울과 삶의 질은 역 상관관계(r=-.745, p=.004)이며, 사회적 지지(r=.544, p=.000), 여가활동(r=.480, p=.024)과 경제활동(r=.711, p=.001)은 순 상관관계를 나타내었다. 또한 사회적 지지와 사회적 활동의 조절효과는 없었고 사회적 활동의 매개효과도 없었다. 그러나 사회적 지지의 매개효과는 있는 것으로 나타났다. 즉 사회적 지지와 사회적 활동의 조절효과가 없어서 사회적 지지와 사회적 활동이 여성독거노인의 우울과 상호작용하여 삶의 질을 높일 수 있다고 할 수 없다. 사회적 지지의 매개효과는 존재하는 것으로 나타나, 여성독거노인의 우울은 사회적 지지를 통하여 그 정도가 완화되며 사회적 지지가 높을수록 삶의 질이 높아지는 것으로 나타났다. 추후 사회적 지지 프로그램을 개발하여 여성독거노인의 우울과 삶의 질에 영향을 미치도록 유도하며, 사회적 활동에 대한 조절효과와 매개효과에 대한 반복연구가 필요하다. The purpose of this study was to examine the moderating and mediating effects of social support and social activity on the relationship between depression and quality of life in elderly women living alone. Subjects were 129 elderly living alone at K city in C province, from June to July, 2010. The data was analyzed using the SPSS program for descriptive statistics, Pearson's correlation coefficient and stepwise multiple regression. The degree of depression of elderly living alone was above the average(2.65), and that of quality of life was average(2.80). The correlated factors of quality of life among elderly women living alone included depression(r=-.745, p=.004), social support(r=.544, p=.000), leisure activity(r=.480, p=.024), and economic activity(r=.711, p=.001). Social support was an important mediator between the depression and quality of life in elderly women living alone. The moderating effects of social support and social activity between depression and quality of life in elderly women living alone were not significant. This study suggests that social support considered in enhancing the quality of life programs designed for elderly living alone. Further research needs to be done to refine moderating and mediating effects of social support, social activity including leisure activity, economic activity and volunteer activity.

Radiation stability and radiolysis mechanism of hydroxyurea in HNO3 solution: Alpha, beta, and gamma irradiations

Qin Yilin,Liao Wei,Lan Tu,Li Fengzhen,Li Feize,Yang Jijun,Liao Jiali,Yang Yuanyou,Liu Ning 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.12

Hydroxyurea (HU) is a novel salt-free reductant used potentially for the separation of U/Pu in the advanced PUREX process. In this work, the radiation stability of HU were systematically investigated in solution by examining the effects of the type of rays (a, b, and g irradiations), the absorbed dose (10 e50 kGy), and the HNO3 concentration (0e3 mol L1 ). The influence degree on HU radiolysis rates followed the order of the absorbed dose > the ray type > the HNO3 concentration, but the latter two had moderate effects on HU radiolysis products where NH4 þ and NO2 were found to be the most abundant ones, suggesting that the differences of a, b, and g rays should be considered in the study of irradiation effects. The radiolysis mechanism was explored using density functional theory (DFT) calculations, and it proposed the dominant radiolysis paths of HU, indicating that the radiolysis of HU was mainly a free radical reaction among $H, eaq e , H2O, intermediates, and the radiolytic free radical fragments of HU. The results reported here provide valuable insights into the mechanistic understanding of HU radiolysis under a, b, and g irradiations and reliable data support for the application of HU in the reprocessing of spent fuel.

Structural behavior of the stiffened double-skin profiled composite walls under compression

Ying Qin,Yong-Wei Li,Xu-Zhao Lan,Yu-Sen Su,Xiang-Yu Wang,Yuan-De Wu 국제구조공학회 2019 Steel and Composite Structures, An International J Vol.31 No.1

Steel-concrete composite walls have been proposed and developed for applications in various types of structures. The double-skin profiled composite walls, as a natural development of composite flooring, provide structural and architectural merits. However, adequate intermediate fasteners between profiled steel plates and concrete core are required to fully mobilize the composite action and to improve the structural behavior of the wall. In this research, two new types of fasteners (i.e., threaded rods and vertical plates) were proposed and three specimens with different fastener types or fastener arrangements were tested under axial compression. The experimental results were evaluated in terms of failure modes, axial load versus axial displacement response, strength index, ductility index, and load-strain relationship. It was found that specimen with symmetrically arranged thread rods sustained more stable axial strain than that with staggered arranged threaded rods. Meanwhile, vertical plates are more suitable for practical use since they provide stronger confinement to profiled steel plate and effectively prevent the steel plate from early local buckling, which eventually enhance the composite action and increase the axial compressive capacity of the wall. The calculation methods were then proposed and good agreement was observed between the test results and the predicted results.