Further Study on Infectivity of Zoophilic and Anthropophilic Strains of Schistosoma Japanicum to Different Races of Oncomelania hupensis Snails

Lee, K.M.,Fan, P.C.,Wu, C.C.,Liu, C.Y. INSTITUTE OF TROPICAL MEDICINE YONSEI UNIVERSITY 1994 YONSEI REPORTS ON TROPICAL MEDICINE Vol.25 No.1

In the present study, Oncomelnia snails were collected from Chen-shan District of I-lan County, Pu-yen District of Chang-hua County, Chang-hu District of Yun-lin County, Pali District and A-li-lao of Taipei County, and Liu-kuei District of Kao-hsiung County. The Oncomelania snails from A-li-lao were infected with Hupei/China strain of Schistosoma japonicum (anthropophilic type). The remaining five races of Oncomelania snails were infected with Han-pao/Taiwan strain of S. japonicum (zoophilic type). Each snail was infected with five miracidia and examined six times after infection. Except for the snails from Liu-Kuei, those from the other five areas were found positive. The infection rate of the snails infected with the zoophilic strain of S. japonicum was the highest in those from Pa-li (42.9%), followed by Chang-Hu (38.4%), Pu-Yen (17.1%). and Chen-Shan (10%). The Oncomelania snails from A-li-lao infected with the anthropophilic strain of S. japonicum gave an infection rate of 53%. The snails from A-il-lao and Pa-li were O. hupensis chiui and those from the other four areas were O. hypensis formosana. In contrast to the order of infection rate. the size of the Chang-hua strain of O. h. formosana was the largest (6.3×2.9mm ) and the A-li-lao strain of O. h. chiui was the smallest (4.2×2.3mm). The Pa-li strain of O. h. chiui snails was middle size (4.8×2.7mm). The infection rate and the size of snails were turned out to be negatively correlated.

A Joint Control Strategy for Automobile Active Grille Shutter and Cooling Fan

Liu Chuanbo,Wang Zhengju,Fan Chaojie,Zhang Ruonan,Man Xingjia 한국자동차공학회 2021 International journal of automotive technology Vol.22 No.6

As an emerging technology improving fuel consumption, active grille shutter (AGS) has been applied in engine cooling system. For the reason of unreasonable matching method of grille opening and cooling fan, the problem of engine overcooling is widespread. As components with similar function of adjusting cooling air flow, the AGS and the cooling fan are separated from each other in parameter matching and operation which reduce cooling efficiency and fuel economy. To achieve precise cooling and improve fuel economy, a joint control strategy for AGS and cooling fan was proposed by using computational fluid dynamics. In order to verify the feasibility of the strategy, the fuel economy tests were carried out at 0 km/h, 90 km/h and 120 km/h, respectively. The results showed that the fuel consumption under the three working conditions was reduced by 0.01 L/ 100 km, 0.07 L/ 100 km and 0.13 L/ 100 km, respectively, indicating that the proposed strategy can significantly reduce fuel consumption.

Enhancement on antioxidant and antibacterial activities of Brightwell blueberry by extraction and purification

Liu Haonan,Wu Han,Wang Ying,Wang Fan,Liu Xiaoli,Zhou Jianzhong 한국응용생명화학회 2021 Applied Biological Chemistry (Appl Biol Chem) Vol.64 No.6

A blueberry anthocyanin extract was obtained from Brightwell blueberry fruits cultivated in eastern China and the extraction and purification conditions were optimized. The components of the anthocyanin extract were identified using ultra-performance liquid chromatography-electrospray ionization interface-mass spectrometer. The antioxidant and antibacterial activities of the blueberry fruit supernatant (BFS), blueberry anthocyanin crude extract (BCE), and blueberry anthocyanin rich extract (BRE) were evaluated. The extraction yield was 1.79 ± 0.0014 mg/g under the following optimal conditions: 1:20 solid-to-liquid ratio (v/w), 24 h, 34 °C, and 90% ethanol containing 0.21% (v/v) hydrochloric acid. With regard to purification, anthocyanin purity increased 19.1-fold. Nine fractions were identified as the glycosides of delphinidin, cyanidin, petunidin, and malvidin. The biological activities of the blueberry anthocyanin extract were improved through extraction and purification. Compared with BFS and BCE, BRE had a higher DPPH radical scavenging activity ( EC50 = 0.51 mg/mL), ABTS antioxidant capacity ( EC50 = 0.32 mg/mL), and oxygen radical absorbance capacity (0.43 mmol Trolox/g). Furthermore, BRE (2 mg/mL) showed a maximum of 84.64 ± 0.35% reduction in the biofilm biomass of Listeria monocytogenes and the inhibition zone given by BRE against Escherichia coli was 16.04 ± 0.38 mm. BRE showed the highest antioxidant capacities and obvious antibacterial effects against foodrelated microorganisms than the other samples. Therefore, BRE can be used as a natural antioxidant and antibacterial agent and has potential health advantages and food industry applications.

A short-term supranutritional vitamin E supplementation alleviated respiratory alkalosis but did not reduce oxidative stress in heat stressed pigs

Fan Liu,Pietro Celi,Surinder Singh Chauhan,Jeremy James Cottrell,Brian Joseph Leury,Frank Rowland Dunshea 아세아·태평양축산학회 2018 Animal Bioscience Vol.31 No.2

Objective: Heat stress (HS) triggers oxidative stress and respiratory alkalosis in pigs. The objective of this experiment was to study whether a short-term supranutritional amount of dietary vitamin E (VE) can mitigate oxidative stress and respiratory alkalosis in heat-stressed pigs. Methods: A total of 24 pigs were given either a control diet (17 IU/kg VE) or a high VE (200 IU/kg VE; HiVE) diet for 14 d, then exposed to thermoneutral (TN; 20°C, 45% humidity) or HS (35°C, 35% to 45% humidity, 8 h daily) conditions for 7 d. Respiration rate and rectal temperature were measured three times daily during the thermal exposure. Blood gas variables and oxidative stress markers were studied in blood samples collected on d 7. Results: Although HiVE diet did not affect the elevated rectal temperature or respiration rate observed during HS, it alleviated (all p<0.05 for diet×temperature) the loss of blood CO2 partial pressure and bicarbonate, as well as the increase in blood pH in the heat-stressed pigs. The HS reduced (p = 0.003) plasma biological antioxidant potential (BAP) and tended to increase (p = 0.067) advanced oxidized protein products (AOPP) in the heat-stressed pigs, suggesting HS triggers oxidative stress. The HiVE diet did not affect plasma BAP or AOPP. Only under TN conditions the HiVE diet reduced the plasma reactive oxygen metabolites (p<0.05 for diet× temperature). Conclusion: A short-term supplementation with 200 IU/kg VE partially alleviated respiratory alkalosis but did not reduce oxidative stress in heat-stressed pigs.

Correction method for calculating junction temperature considering parasitic effects in SiC MOSFETs

Fan Liu,Mingxing Du,Jinliang Yin,Chao Dong,Ziwei Ouyang 전력전자학회 2023 JOURNAL OF POWER ELECTRONICS Vol.23 No.4

The turn-on change rate of drain current diDS(on)/dt is an electrical parameter that is suitable for the online monitoring of junction temperature in SiC MOSFETs. In practical applications, the change of an external circuit changes the temperature-sensitive characteristic of diDS(on)/dt. In this paper, a SiC MOSFET in a Buck converter is taken as the research object. First, it is theoretically derived and experimentally verified that the power loop inductance and drive loop resistance are parasitic parameters that affect the temperaturesensitive characteristic of diDS(on)/dt. Second, according to the spectrum peak characteristics caused by the drain–source turn-off oscillation voltage of the SiC MOSFET, the theoretical relationship between the diDS(on)/dt temperature-sensitive characteristic and the peak of the drain–source turn-off oscillation voltage is studied. It is concluded that the spectrum peak can reflect the change of the diDS(on)/dt temperature-sensitive characteristic caused by the change of the parasitic parameters. Based on the above research, a model of a modified diDS(on)/dt temperature-sensitive characteristic considering parasitic effect is established in this paper. Through experimental verification, this model can largely eliminate the junction temperature monitoring error caused by the change of the external circuit.

Tissue distribution of marbofloxacin in pigs after a single intramuscular injection

Fan Yang,Yiming Liu,Zhili Li,Yuqin Wang,Baobao Liu,Zhensheng Zhao,Bianhua Zhou,Guoyong Wang 대한수의학회 2017 Journal of Veterinary Science Vol.18 No.2

Tissue distribution of marbofloxacin was studied in pigs after a single intramuscular injection at 2.5 mg/kg body weight. Samples of plasma, muscle, liver, kidney, heart, lung, and muscle at the injection site were randomly collected from five pigs at 2, 6, 10, 24, 48, 72, and 96 h after administration. Marbofloxacin concentrations were determined by using high-performance liquid chromatography with ultraviolet detection and were subjected to non-compartmental analysis to obtain kinetic parameters. The elimination half-life (t1/2lz) of marbofloxacin at the injection site was 22.12 h, while those in kidney, plasma, liver, lung, heart, and muscle were 16.75, 21.48, 21.84, 24.00, 24.45, and 28.91 h, respectively. Areas under the concentration-time curve from 0 h to ∞ (AUC0–∞s) were calculated to be 31.17 hㆍmgㆍmL−1 for plasma and 32.97, 33.92, 34.78, 37.58, 42.02, and 98.80 hㆍmgㆍg−1 for heart, muscle, lung, liver, kidney, and injection site, respectively. The peak concentration (Cmax) of marbofloxacin was 1.62 µg/mL in plasma and 1.71, 1.74, 1.86, 1.93, 2.45, and 7.64 µg/g in heart, lung, muscle, kidney, liver, and injection site, respectively. The results show that marbofloxacin was fast absorbed, extensively distributed, and slowly eliminated from pigs after a single intramuscular administration.

Reduced graphene oxide/polypyrrole composite: an advanced electrode for high-performance symmetric/asymmetric supercapacitor

Liu Guijing,Shi Yanying,Wang Lei,Song Yadong,Gao Shanmin,Liu Dong,Fan Leqing 한국탄소학회 2020 Carbon Letters Vol.30 No.4

Polypyrrole (PPy) decorated on reduced graphene oxide (rGO) flms is successfully prepared with pyrrole (Py) monomers and rGO through one-step combining oxidation with polymerization reaction. Compared with the pure individual compo�nents, rGO/PPy compound turns out better electrochemical characteristics owing to the introduction of rGO sheets, which improves the specifc surface area and the conductivity of composite material. When the amount of rGO is 10% of the total, the rGO/PPy compound delivers the best capacitance of 389.3 F g−1 at 1.0 A g−1 in a three-electrode system and 266.8 F g−1 at 0.25 A g−1 in the symmetric supercapacitor system. In addition, asymmetric device (rGO/PPy//AC) has been success�fully fabricated using optimized rGO/PPy compound as positive electrode, activated carbon as negative electrode (AC) and 1 M Na2SO4 aqueous solution as electrolyte. The device obtains long cycle stability under the high-voltage region from 0 to 1.6 V, meanwhile displaying the satisfed energy density of 19.7 Wh kg−1 at 478.1 W kg−1. Besides, the rGO/PPy//AC device presents satisfactory rate capability and long life time.

Research on Color Gray Code Encoding and Color Components Correction in 3D Measurement for Color Object

Fan Jianying,Liu Linchao,Gao Yang,Zhang Zeliang,Yu Lei,Liu Wei 보안공학연구지원센터(IJSIP) 2013 International Journal of Signal Processing, Image Vol.6 No.5

Association of a novel antisense lncRNA TP73-AS1 polymorphisms and expression with colorectal cancer susceptibility and prognosis

Fan Jiayao,Xu Huiqing,Liu Bing,Jing Fangyuan,He Qingfang,Zheng Shasha,Shi Haining,Jiao Lefei,Fan Chunhong 한국유전학회 2022 Genes & Genomics Vol.44 No.7

Background: TP73-AS1 is a novel antisense long noncoding RNA and plays an important role in cell proliferation and cancer development. However, the link between TP73-AS1 and colorectal cancer (CRC) has not yet been reported. Objective: To explore the association of genetic variants in TP73-AS1 and its expression with CRC susceptibility and prognosis. Methods: A case-control study (including 507 CRC cases and 503 controls) and bioinformatics analysis were conducted. Results: rs9800 polymorphism was significantly related to higher risk in CRC [adjusted odds ratio (AOR) = 1.33, 95% confidence interval (CI) = 1.02-1.75, P = 0.034 in heterozygote codominant model]. There was no difference between TP73-AS1 polymorphisms and different tumor node metastasis (TNM) stages in the adjusted model. Moreover, TP73-AS1 expression level was positively related to different TNM stages. After adjusted for age, gender and TNM, higher TP73-AS1 expression levels were related to shorter recurrence-free survival time [hazard ratio (HR) = 1.66, 95% CI = 1.02-2.71, P = 0.043]. Conclusion: TP73-AS1 polymorphisms and expression may be associated with susceptibility and prognosis of CRC.

Effect of Cu on Pore Structure of Al–Si Foam

Fan Deng,Jianzhong Fan,Yanqiang Liu,Xuehan Lu,Shaohua Wei,Junhui Nie 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.12

The alloy composition is an important factor effecting the pore structure of aluminum foam. In this paper, the powder compactfoaming method was used, and different content of Cu element powders were added to the alloy Al–9Si, for investigatingthe effect of alloying element on foaming process. With the Cu content of Al–Si–Cu alloy increasing, the expansion ratio isincreased, the time required to reach maximum expansion is shortened, and the number of fissure-like pores at early foamingstage is decreased. This improving action is related to the higher volume fraction of liquid phase in same melting temperaturecaused by increasing Cu content in alloy. Comparing different Al–Si–Cu alloys with different Cu content at same expansionratio, the higher Cu content, the smaller pore size and the thinner cell wall. This beneficial effect on pore structure is attributedto the addition of Cu that is benefit to increasing the viscosity of Al–Si–Cu alloy during foaming. And at same expansionrate, the more content of Cu in Al–Si–Cu alloy, the higher compressive strength of aluminum foam.