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좀비 드라마의 부권 서사: <워킹 데드>의 남성성과 부성 분석
김태형 ( Kim¸ Taehyung ) 대한영어영문학회 2021 영어영문학연구 Vol.47 No.2
The research examines the logic of the patriarchal society that runs throughout the narrative of the television series The Walking Dead. Males in the zombified world often strike out the living dead through violence, which affects people’s sometimes unethical and deadly behaviors toward other human beings. The family and community also take advantage of such masculine violence for their survival. The protagonist of the series, Rick Grimes, becomes the head of the family and survivor group by eliminating or winning over competitors for the name of the father. Rick’s son, Carl, stands up for his biological father among other father figures, supporting Rick’s patrilineal system. Women in the community need toughness and masculinity to adapt to the changed circumstances; mother figures in Rick’s family die providing house work, which is especially undervalued in a zombie apocalypse. Carl has to decide not between his mother and his father in an Oedipal triad but between fathers as a consequence of his mother’s absence. The logic of patriarchy takes up the main narrative of the series, and the longing for the missing Rick ultimately proves the father’s symbolic authority in his absence. (Kunsan National University)
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Kim, TaeHyung,Tyndel, Marc S.,Kim, Hyeoung Joon,Ahn, Jae-Sook,Choi, Seung Hyun,Park, Hee Jeong,Kim, Yeo-kyeoung,Kim, Soo Young,Lipton, Jeffrey H.,Zhang, Zhaolei,Kim, Dennis (Dong Hwan) American Society of Hematology 2017 Blood Vol. No.
<P>Somatic mutations commonly detected in a variety of myeloid neoplasms have not been systematically investigated in chronic myeloid leukemia (CML). We performed targeted deep sequencing on a total of 300 serial samples from 100 CML patients; 37 patients carried mutations. Sixteen of these had evidence of mutations originating from preleukemic clones. Using unsupervised hierarchical clustering, we identified 5 distinct patterns of mutation dynamics arising following tyrosine kinase inhibitor (TKI) therapy. This study demonstrates that patterns of mutation acquisition, persistence, and clearance vary but have a number of interesting correlations with clinical outcomes. Mutation burden often persisted despite successful TKI response (pattern 1), providing indirect evidence that these mutations also originated from preleukemic mutations, whereas patients exhibiting mutation clearance (pattern 3) showed mixed clinical outcomes. Unsurprisingly, patients acquiring new mutations during treatment failed TKI therapy (pattern 2). These patterns show that CML mutation dynamics following TKI therapy are markedly distinct from other myeloid neoplasms. In summary, clinical implications of mutation profiles and dynamics in CML should be interpreted with caution.</P>
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Kim, Tae-Gon,Kim, Taehyung,Kim, Jaegyeom,Kim, Seung-Joo,Im, Seoung-Jae American Chemical Society 2014 The Journal of Physical Chemistry Part C Vol.118 No.23
<P>The crystal structure of β-Ca<SUB>3</SUB>SiO<SUB>4</SUB>Cl<SUB>2</SUB> was determined by the <I>ab initio</I> structure determination method based on the synchrotron powder XRD data for the first time, and the luminescence properties of a Eu<SUP>2+</SUP>-doped β-Ca<SUB>3</SUB>SiO<SUB>4</SUB>Cl<SUB>2</SUB> phosphor were characterized. β-Ca<SUB>3</SUB>SiO<SUB>4</SUB>Cl<SUB>2</SUB> was found to be monoclinic (space group <I>P</I>2<SUB>1</SUB>/<I>c</I>) with the lattice parameters, <I>a</I> = 5.91234(1) Å, <I>b</I> = 10.20128(1) Å, <I>c</I> = 10.98866(1) Å, β = 90.3423(1)°. This structure can be considered as an intergrowth structure built up from alternating stacks of two layered sublattices, <SUB>∞</SUB><SUP>2</SUP>[Ca<SUB>2</SUB>SiO<SUB>4</SUB>] and <SUB>∞</SUB><SUP>2</SUP>[CaCl<SUB>2</SUB>], along the [100] direction. In this structure, the Ca atoms occupy three crystallographically distinct sites: Ca1O<SUB>4</SUB>Cl<SUB>3</SUB>, Ca2O<SUB>5</SUB>Cl<SUB>2</SUB>, and Ca3O<SUB>3</SUB>Cl<SUB>4</SUB>. The photoluminescence of the Eu<SUP>2+</SUP>-doped Ca<SUB>3</SUB>SiO<SUB>4</SUB>Cl<SUB>2</SUB> phosphor excited at 450 nm blue light shows the 150 nm wide-band emission peaked at 635 nm with about 70% quantum efficiency. The photoluminescence properties, such as centroid shifts, crystal-field splitting, and Stokes shifts, were correlated with the crystal structure through the calculation of shared-electron populations reflecting the bond covalency between Ca and O/Cl. Effects of doping concentrations on the luminescence spectra and temperature stability were also discussed based on the inhomogeneous energy transfer property determined by the structural geometric factor.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jpccck/2014/jpccck.2014.118.issue-23/jp5002379/production/images/medium/jp-2014-002379_0011.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/jp5002379'>ACS Electronic Supporting Info</A></P>
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Kim Taehyung,Kim Jeongun,Kim Engchan 한국물리학회 2022 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.81 No.11
Three-dimensional (3D) printing technology has been widely used to fabricate customized phantom for patients. High-density structures, such as bone, are not easy to reproduce with regular flaments and require high-density materials. In this study, we use polylactic acid+ (PLA+) flaments and fve metal flaments (bronze, copper, aluminum, iron, and tungsten) containing metal powder to investigate variations in the Hounsfeld unit (HU) values refected in computed tomography images under flament and printing output conditions. Samples were produced to verify the element composition using each flament, and scanning electron microscopy–energy dispersive spectroscopy (SEM–EDS) analyses were performed. The variations of HU values according to the infll patterns were verifed using PLA+, and six flaments were used to verify the variation in HU values according to the infll rate. SEM–EDS analysis shows that all flaments contain C and O elements in common and account for the largest proportion. In the case of metal flaments, additional elements were observed: Cu (1.77%) in bronze, Na (0.45%) and Al (4.48%) in aluminum, Ca (0.7%) and Fe (2.54%) in iron, and W (1.61%) in tungsten. Linearity was confrmed according to the infll rates using various infll patterns. The results showed high linearity of 0.99 or higher in the determination coefcient (R-squared; R2 ) of most patterns. However, in the case of the full honeycomb (R2=0.8825) and fast honeycomb (R2=0.9606) patterns, HU values increased rapidly or gradually at a certain infll rate, indicating a relatively low determination coefcient. The measurement of the variation in HU value according to the type of flament and the degree of flling showed that the higher the degree of flling, regardless of the type of flament, the higher the HU value. For a 100% fll ratio, the average HU value of the cube output to each flament was measured diferently at−28.7, 526.3, 70.1,−32.3, and 3061 HU for PLA+, bronze, copper, iron, and tungsten, respectively. This study will help express various HU values using 3D printing. Moreover, metal flaments will positively afect reproducing dense anatomical structures, such as bones, which have been difcult to express in previous studies.
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Kim, TaeHyung,Tyndel, Marc S.,Zhang, Zhaolei,Ahn, Jaesook,Choi, Seunghyun,Szardenings, Michael,Lipton, Jeffrey H.,Kim, Hyeoung-Joon,Kim Dong Hwan, Dennis Elsevier 2017 Leukemia research Vol.59 No.-
<P><B>Abstract</B></P> <P><B>Objective</B></P> <P>The development of tyrosine kinase inhibitors (TKIs) has significantly improved the treatment of chronic myeloid leukemia (CML). However, approximately one third of patients are resistant to TKI and/or progress to advanced disease stages. TKI therapy failure has a well-known association with <I>ABL1</I> kinase domain (KD) mutations, but only around half of TKI non-responders have detectable <I>ABL1</I> KD mutations.</P> <P><B>Method</B></P> <P>We attempt to identify genetic markers associated with TKI therapy failure in 13 patients (5 resistant, 8 progressed) without <I>ABL1</I> KD mutations using whole-exome sequencing.</P> <P><B>Results</B></P> <P>In 6 patients, we detected mutations in 6 genes commonly mutated in other myeloid neoplasms: <I>ABL1</I>, <I>ASXL1</I>, <I>DNMT3A</I>, <I>IDH1</I>, <I>SETBP1</I>, and <I>TP63</I>. We then used targeted deep sequencing to validate our finding in an independent cohort consisting of 100 CML patients with varying drug responses (74 responsive, 18 resistant, and 8 progressed patients). Mutations in genes associated with epigenetic regulations such as <I>DNMT3A</I> and <I>ASXL1</I> seem to play an important role in the pathogenesis of CML progression and TKI-resistance independent of <I>ABL1</I> KD mutations.</P> <P><B>Conclusion</B></P> <P>This study suggests the involvement of other somatic mutations in the development of TKI resistant progression to advanced disease stages in CML, particularly in patients lacking <I>ABL1</I> KD mutations.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Acquisition of somatic mutation is associated with TKI therapy failure and progression in CML patients. </LI> <LI> Exome sequencing revealed mutations in 6 genes: <I>ABL1, ASXL1, DNMT3A, IDH1, SETBP1,</I> and <I>TP63.</I> </LI> <LI> Somatic mutations is responsible for TKI resistance esp. lacking <I>ABL1</I> KD mutations. </LI> </UL> </P>
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김태형(Taehyung Kim),김진(Jin Kim),금재성(Jaesung Keum),태재호(Jaeho Tae),김선홍(Sunhong Kim),홍대희(Daehie Hong) 대한설비공학회 2008 대한설비공학회 학술발표대회논문집 Vol.2008 No.2
Since tunnel construction order was placed one by one, various sensors and actuators installed at the RTU and higher level system in each tunnel maintenance office had their own protocols depending on construction company. The TGMS testbed established on the extended region of Yong-dong Highway, for example, did not have consistent protocol between each automation levels and management levels without considering the functions and/or roles of each level. The management sever in each tunnel was simply networked to the TGMS server. Therefore, it is impossible to implement a new control algorithm as well as to integrate each other since each tunnel was constructed by different company. So, if the construction company is out of business, there is no way to maintain the corresponding tunnel effectively. In order to solve this problem, all the necessary standard protocols was established between automation level and management levels. These interface standards provide the clear classification between individual tunnel system and tunnel management system. So, even if construction company is different, its effect is minimized, so that it is expected to successfully establish PC based TGMS.
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