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RISS 인기검색어
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- 저자 : Kemin Li (검색결과 3 건)
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Li Ping,Chang Xuelian,Chen Xiaoyu,Tang Tiantian,Liu Yajing,Shang Yu,Qi Kemin 한국미생물학회 2022 The journal of microbiology Vol.60 No.8
The maturation of infant gut microbiota has lifelong implications on health, which has been proposed as the major events during the first year of life. However, little is known about their dynamic colonization and influencing elements among the first two-year infancy as well as into the adulthood. So based on the 16S rRNA sequencing data among 30 healthy breast-feeding mother-infant pairs with normal ranges of growth and development indicators from birth to two years old, the dynamic colonization of gut microbiota and its influencing factors were discussed using this birth cohort. Among these, we identified that the diversity of gut microbiota was significantly increased from six-month to two-year subgroups. The significantly dynamic trends of gut microbiota at the phylum (genus) level were that the percents of Firmicutes (Faecalibacterium, Blautia, Enterococcus, Subdoligranulum, Agathobacter, unidentified_Erysipelotrichaceae, Staphylococcus, unidentified_Ruminococcaceae, and Fusicatenibacter), Bacteroidetes and Verrucomicrobia were increased, while Actinobacteria (Bifidobacterium) and Proteobacteria (unidentified- Enterobacteriaceae and Klebsiella) were decreased with the increased ages from six months to two years old, which might simultaneously modulate the host pathways, such as the higher percents of chemoheterotrophy and fermentation, and lower percentages of nitrate_reduction, aerobic_chemoheterotrophy and so on. Furthermore, there were significant associations between maternal (milk microbiota, pre-pregnancy BMI, BMI increment during the pregnancy)/infant characteristics (BMI at birth and BMI gain), and the compositions of gut microbiota. However, no differences of gut microbiota were shown between the different sex and productive mode subgroups. Overall, the colonization of gut microbiota is significantly matured into the adulthood with the increased ages to two-years old and regulated by the above maternal/infant characteristics, which will provide a new direction for the host-gut microbiota interplay during the first two years of life.
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Conceptual configuration and seismic performance of high-rise steel braced frame
Shengfang Qiao,Xiaolei Han,Kemin Zhou,Weichen Li 국제구조공학회 2017 Steel and Composite Structures, An International J Vol.23 No.2
Conceptual configuration and seismic performance of high-rise steel frame-brace structure are studied. First, the topology optimization problem of minimum volume based on truss-like material model under earthquake action is presented, which is solved by full-stress method. Further, conceptual configurations of 20-storey and 40-storey steel frame-brace structure are formed. Next, the 40-storeystructure model is developed in Opensees. Two common configurations are utilized for comparison. Last, seismic performance of 40-storey structure is derived using nonlinear static analysis and nonlinear dynamic analysis. Results indicate that structural lateral stiffness and maximum roof displacement can be improved using brace. Meanwhile seismic damage can also be decreased. Moreover, frame-brace structure using topology optimization is most favorable to enhance lateral stiffness and mitigate seismic damage. Thus, topology optimization is an available way to form initial conceptual configuration in high-rise steel frame-brace structure.
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National screening programs for cervical cancer in Asian countries
Eiko Saitoh Aoki,Rutie Yin,Kemin Li,Neerja Bhatla,Seema Singhal,Dwiana Ocviyanti,Kumiko Saika,서민아,김미선,Wichai Termrungruanglert 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.3
Cervical cancer is still one of the most common female cancers in Asia and the leading cause of cancer-related deaths in low- and middle-income countries. Nowadays, national screening programs for cervical cancer are widely provided in Asian countries. We reviewed the National Cancer Screening Program (NCSP) in China, India, Indonesia, Japan, Korea, and Thailand. The NCSP were established at varying times, from 1962 in Japan to 2014 in Indonesia. The primary screening method is based on cytology in all countries except for India and Indonesia. In India and Indonesia, visual inspection of the cervix with acetic acid (VIA) is mainly used as a primary screening method, and a “see and treat” strategy is applied to women with a positive VIA result. The starting age of NCSP ranges from 18 years in China to 30 years in Thailand. The screening interval is 2 years in all countries except for China and Indonesia, in which it is 3 years. Uptake rates of NCSP vary from 5.0%–59.7%. Many women in low- and middle-income countries still do not participate in NCSP. To improve uptake rates and thereby prevent more cases of cervical cancer, Asian countries should continue to promote NCSP to the public using various approaches.
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