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Increased risk of gastric cancer in workers with occupational dust exposure
( Mo-yeol Kang ),( Jiyoun Jung ),( Jung-wan Koo ),( Inah Kim ),( Hyoung-ryoul Kim ),( Jun-pyo Myong ) 대한내과학회 2021 The Korean Journal of Internal Medicine Vol.36 No.0
Background/Aims: Workers who are exposed to dust in the workplace tend to show a higher incidence of gastric cancer. Nevertheless, scientific evidence to support an association between dust exposure and the risk of gastric cancer is inadequate. This study aimed to investigate whether or not occupational dust exposure influences the risk of gastric cancer. Methods: We collected the electronic data from the Pneumoconiosis Health Examination (PHE) program, provided by the Ministry of Employment and Labor and the Korea Workers’ Compensation and Welfare Service from 2002 to 2017. The PHE database was linked to the National Health Insurances databases. The age-standardized incidence ratio (SIR) and 95% confidence intervals (CIs) of the risk of gastric cancers were evaluated in workers with occupational dust exposure, and the results were compared to those in the general population. Results: From 2004 to 2015, 1,543 cases of gastric cancer were observed in the male participants, as compared with 1,174 of expected cases, which yielded an SIR of 1.314 (95% CI, 1.249 to 1.380). Under dust exposure, the risk of gastric cancer was increased 23.9% in the male participants (95% CI, 19.9 to 27.5), and the degree of impairment of lung function was inversely related to the risk of gastric cancer. Conclusions: Workers with occupational dust exposure were at higher risk of developing gastric cancer than the general population. Thus, future efforts for the prevention of gastric cancer are necessary for dust exposed workers.
Long working hours and cardiovascular disease: a meta-analysis of epidemiologic studies.
Kang, Mo-Yeol,Park, Hyunseung,Seo, Jeong-Cheol,Kim, Donghoon,Lim, Youn-Hee,Lim, Sinye,Cho, Soo-Hun,Hong, Yun-Chul Lippincott Williams & Wilkins 2012 Journal of Occupational and Environmental Medicine Vol.54 No.5
<P>To conduct a meta-analysis from published studies to evaluate the relationship between long working hours and the risk of cardiovascular disease (CVD).</P>
Heejoo Ko(Heejoo Ko),Dohwan Kim(Dohwan Kim),Seong-Sik Cho(Seong-Sik Cho),Mo-Yeol Kang(Mo-Yeol Kang) 한국역학회 2023 Epidemiology and Health Vol.45 No.-
OBJECTIVES: The physical activity paradox suggests that occupational physical activity (OPA), unlike leisure-time physical activity (LTPA), may detrimentally impact health. We explored the relationships of OPA and LTPA with work ability (WA) and health-related productivity loss (HRPL). METHODS: This study included 5,501 workers in Korea who were recruited in 2021 through a web-based cross-sectional questionnaire. The questionnaire was utilized to quantify OPA and LTPA in metabolic equivalents, while WA and HRPL were also measured. Non-parametric regression, using a generalized additive model (GAM), was employed to visualize the relationships of LTPA and OPA with WA and HRPL. Mean differences in WA and HRPL, in relation to OPA and LTPA, were examined using linear regression models. These models were adjusted for covariates including sex, age, body mass index, education level, alcohol consumption, smoking history, insomnia, occupation, hours worked, and income. RESULTS: The GAM and linear regression analyses revealed that higher LTPA corresponded with higher WA and lower HRPL. In contrast, as OPA increased, WA decreased and HRPL increased. However, within the group with high OPA, HRPL was not significantly lower in the high-LTPA subgroup relative to the low-LTPA subgroup (mean difference=1.92%, p=0.343). This pattern was especially pronounced among workers aged 60 years and older, with an increase in HRPL observed with increasing LTPA among the respondents with high OPA. CONCLUSIONS: High LTPA levels were associated with elevated WA and diminished HRPL. In contrast, higher levels of OPA were associated with lower WA and higher HRPL.
S-336 A Case report : Secondary hypertrophic osteoarthropathy with early stage lung cancer
( Kang Mo Gu ),( Joo Young Lee ),( Jae Chol Choi ),( Jong Wook Shin ),( Jae Yeol Kim ),( In Won Park ),( Byoung Whui Choi ),( Jae Woo Jung ) 대한내과학회 2016 대한내과학회 추계학술발표논문집 Vol.2016 No.1
Introduction:?Hypertrophic osteoarthropathy (HOA) occurs 5-10% patients with advanced lung cancer. Typical HOA characterized by clubbing of digits, periosteal new-bone formation and synovial effusion. In early stage of lung cancer, severe joint pain may be the presenting symptom of HOA and may precede clubbing of digits. We report a rare case of HOA combined with early stage of lung cancer.?Case:?A 52-year-old man with severe both knee joint pain and edema presented with a 4-month history. In physical examination, ballotment of patella and severe tenderness of knee joints were detected. Bone scan showed bilateral symmetrically increased cortical uptake along femurs and tibias suggested HOA. Laboratory findings were negative for rheumatoid factor and anti-CCP antibody, but the antinuclear antibody titer was 1:80. Joint fluid analysis showed nonspecific arthritis pattern. He suffered from chronic cough at the time knee pain started. For evaluate causes of chronic cough and HOA, chest PA and chest CT scan were done. About 4.5cm sized spiculated mass lesion in the right upper lobe was detected. Percutaneous needle biopsy confirmed adenocarcinoma. The patient received right upper lobectomy by video-assisted thoracoscopic surgery. Pathologic stage was non-small cell lung cancer stage IB (T2aN0M0). One month later, his pain was subsided without medication and bone scan showed decreased cortical uptake of involved bones.