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      • Re-categorizing the Factors of Traffic Crashes Based on a Literature Review

        Joonho Park,Jaehyun So 대한교통학회 2024 대한교통학회 학술대회지 Vol.90 No.-

        This study aimed to identify and reclassify factors influencing traffic crashes through a literature review. Existing factors influencing traffic crashes have been broadly categorized into human factors, vehicle factors, and environmental factors. However, recent advancements in technology and the establishment of standards for various environmental factors necessitate a reclassification of factors influencing traffic crashes. Therefore, literature related to the analysis of traffic crash causes was collected, with a final selection of 62 documents for review. The literature review involved collecting various factors used in the literature and analyzing the significance of each factor in relation to traffic crashes. The review of the 62 documents resulted in the identification of a total of 70 factors significant to traffic crashes. These 70 factors identified through the literature review were grouped based on their characteristics. Ultimately, the 70 factors were classified into 6 groups and 19 subgroups. The findings of this study contribute to the novel identification and reclassification of factors influencing traffic crashes, with the potential to contribute to a clearer understanding and better management of traffic crash causes in the future.

      • Engineering of the electrode structure of thin film solid oxide fuel cells

        Park, Joonho,Lee, Yeageun,Chang, Ikwhang,Lee, Wonyoung,Cha, Suk Won Elsevier 2015 THIN SOLID FILMS - Vol.584 No.-

        <P><B>Abstract</B></P> <P>In this study, we systematically examined the effects of anode structures in nanoporous template-based thin film solid oxide fuel cells on the electrochemical performance. The fuel cells were fabricated by sequential sputtering of the anode, the electrolyte and the cathode on an anodic aluminum oxide substrate without pinhole problems. Systematic investigation showed the substantial impacts of the porosity and the thickness of the Pt anodes on the reactivity at the anode/electrolyte interface and the mass transport in the electrode, which are closely related to the activation and the concentration overpotentials of fuel cells, respectively. Our results provide the fundamental insights into tailoring the anode structures for improved fuel cell performance.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We fabricated thin film SOFCs on the AAO by sequential sputtering. </LI> <LI> The effects of the anode structures on the cell performance were examined. </LI> <LI> We confirmed that higher porosity in the anode can improve the cell performance. </LI> <LI> Optimizing the anode structure in consideration of the AAO pores is required. </LI> </UL> </P>

      • KCI등재

        Imaging Predictors of Survival in Patients with Single Small Hepatocellular Carcinoma Treated with Transarterial Chemoembolization

        Park Chan,Kim Jin Hyoung,Kim Pyeong Hwa,Kim So Yeon,Gwon Dong Il,Chu Hee Ho,Park Minho,Hur Joonho,Kim Jin Young,Kim Dong Joon 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.2

        Objective: Clinical outcomes of patients who undergo transarterial chemoembolization (TACE) for single small hepatocellular carcinoma (HCC) are not consistent, and may differ based on certain imaging findings. This retrospective study was aimed at determining the efficacy of pre-TACE CT or MR imaging findings in predicting survival outcomes in patients with small HCC upon being treated with TACE. Besides, the study proposed to build a risk prediction model for these patients. Materials and Methods: Altogether, 750 patients with functionally good hepatic reserve who received TACE as the first-line treatment for single small HCC between 2004 and 2014 were included in the study. These patients were randomly assigned into training (n = 525) and validation (n = 225) sets. Results: According to the results of a multivariable Cox analysis, three pre-TACE imaging findings (tumor margin, tumor location, enhancement pattern) and two clinical factors (age, serum albumin level) were selected and scored to create predictive models for overall, local tumor progression (LTP)-free, and progression-free survival in the training set. The median overall survival time in the validation set were 137.5 months, 76.1 months, and 44.0 months for low-, intermediate-, and high-risk groups, respectively (p < 0.001). Time-dependent receiver operating characteristic curves of the predictive models for overall, LTP-free, and progression-free survival applied to the validation cohort showed acceptable areas under the curve values (0.734, 0.802, and 0.775 for overall survival; 0.738, 0.789, and 0.791 for LTP-free survival; and 0.671, 0.733, and 0.694 for progression-free survival at 3, 5, and 10 years, respectively). Conclusion: Pre-TACE CT or MR imaging findings could predict survival outcomes in patients with small HCC upon treatment with TACE. Our predictive models including three imaging predictors could be helpful in prognostication, identification, and selection of suitable candidates for TACE in patients with single small HCC.

      • Effect of the thickness of sputtered gadolinia-doped ceria as a cathodic interlayer in solid oxide fuel cells

        Park, Taehyun,Lee, Yoon Ho,Cho, Gu Young,Ji, Sanghoon,Park, Joonho,Chang, Ikwhang,Cha, Suk Won Elsevier 2015 THIN SOLID FILMS - Vol.584 No.-

        <P><B>Abstract</B></P> <P>Sputtered gadolinia-doped ceria (GDC) film was introduced as the cathodic interlayer between an yttria-stabilized zirconia (YSZ) pellet and a Pt cathode in solid oxide fuel cells (SOFCs). The fuel cells with none, 50, 100 and 150nm thick GDC interlayers were fabricated to investigate the effect of the thickness of the GDC interlayer. The performances of the SOFCs with the 100 and 150nm thick GDC interlayers operated at 450°C showed the highest performance. Through electrochemical impedance analysis, it was visualized that the GDC interlayer significantly reduced the faradaic resistance of the SOFC. The degradation of the performance from the increased ohmic resistance by adding the GDC interlayer was negligible. From the topographical images scanned by atomic force microscope, it was observed that the 50nm thick GDC interlayer did not perfectly cover the surface of the YSZ pellet, resulting in incomplete performance enhancement by the sputtered GDC.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Gadolinia-doped ceria was used as a cathodic interlayer in solid oxide fuel cells. </LI> <LI> Sputter was used to deposit gadolinia-doped ceria. </LI> <LI> Gadolinia-doped ceria interlayer improved the electrochemical performance. </LI> <LI> 100nm or thicker gadolinia-doped ceria showed a full functionality as interlayer. </LI> </UL> </P>

      • SCISCIESCOPUS
      • KCI등재

        Tenofovir alafenamide treatment may not worsen the lipid profile of chronic hepatitis B patients: A propensity score-matched analysis

        Joonho Jeong,Jung Woo Shin,Seok Won Jung,Eun Ji Park,Neung Hwa Park 대한간학회 2022 Clinical and Molecular Hepatology(대한간학회지) Vol.28 No.2

        Background/Aims: Tenofovir alafenamide (TAF) has shown less favorable effect on lipids compared to tenofovir disoproxil fumarate (TDF) in clinical trials. However, data regarding these outcomes in patients with chronic hepatitis B (CHB) are scarce. Therefore, this study aimed to evaluate the effect of TAF on the lipid in patients with CHB. Methods: A total of 237 TAF-treated CHB patients compared with TDF, inactive CHB, and non-hepatitis B virus (HBV)- infected control groups using propensity score matching (PSM). Results: Following PSM, each analysis was conducted on cohorts via the matching of 70:140 (TAF:TDF), 89:89 (TAF:inactive CHB), 140:560 (TAF:non-HBV infected control), and 368:1,472 (TDF:non-HBV-infected control). A significant decrease in the total cholesterol (TC) level was noted at 48 weeks in the TDF group compared to the TAF group (176.3±32.9 vs. 156.7±27.7, P<0.001) and the non-HBV-infected control group (175.0±29.5 vs. 156.2±28.3, P<0.001). However, no significant change in TC was observed in the TAF group and inactive CHB or non-HBV-infected control groups at 48 weeks. For the subgroup analyses of TAF vs. non-HBV-infected control subjects and inactive CHB patients whose detailed lipid profile information were available, no between-group differences in TC, low-density lipoprotein (LDL)-cholesterol, highdensity lipoprotein (HDL)-cholesterol, TC/HDL ratio, and LDL/HDL ratio were observed at 48 weeks. Conclusions: TDF seems to have a lipid-lowering effect compared to the non-HBV-infected control and TAF-treated groups. However, in real practice, TAF might not worsen the lipid profiles of subjects compared to non-HBV-infected controls and patients with inactive CHB.

      • S-91 Effect of Rebamipide, Sucralfate and Rifaximin on Radiation Intestinal Injury in Mouse

        ( Joonho Jeong ),( Won Moon ),( Seun Ja Park ),( Moo In Park ),( Sung Eun Kim ),( Jae Hyun Kim ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

        Background: Radiotherapy for malignant abdominopelvic disease results in radiation-induced enterocolitis. However, there is no well-established preventive strategy. The aim is to evaluate the suppressive effect of rebamipide, sucralfate and rifaximin on ionizing radiation (IR)-induced acute inflammation and apoptosis in the intestine of mouse. Methods: Thirty ICR mice were divided into (1) a vehicle-treated control group before sham IR, (2) a vehicle-treated group before IR, and (3-5) rebamipide, sucralfate or rifaximin-treated groups before IR. The intestine was resected at 4 hours after 4 Gy IR to the abdominopelvis. Pro-/anti-inflammatory and pro-/anti-apoptotic factors were investigated. Results: NAMPT was down-regulated after IR, which was attenuated by rebamipide, sucralfate and rifaximin (p<0.05). Activation of NF-κB and phosphorylation of MAPKs were induced by IR, which were suppressed by rebamipide, sucralfate, and rifaximin (p<0.05). TNF-α, IL-1β, and IL-6 were increased by IR, while attenuated by rebamipide, sucralfate, and rifaximin down to similar level of control group (p<0.05). The iNOS, COX-2 and PGE2 were significantly induced by IR, which were attenuated by rebamipide, sucralfate, and rifaximin (p<0.05). ICAM-1 was corresponded to above mentioned results. [Ca2+] oscillation was increased by IR, which was attenuated by rebamipide, sucralfate, and rifaximin. Proapoptotic gene (Bax, c-Myc) and antiapoptotic gene (Bcl-2, Bcl-xL) expressions were potently suppressed and induced, respectively, by rebamipide, sucralfate, and rifaximin. The release of cytochrome C was increased by IR, while it was attenuated by rebamipide, sucralfate, and rifaximin (p<0.05). Caspase 3 and caspase 7 were also elevated by IR compared to control group, however, they showed decline by rebamipide, sucralfate, and rifaximin (p<0.05). Conclusions: This study demonstrated that rebamipide, sucralfate, and rifaximin have the suppressive effects on IR-induced acute inflammation and apoptosis in the intestine of mouse. Rebamipide, sucralfate, and rifaximin may have beneficial effects in preventing acute radiation-induced enterocolitis.

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